Dosage of lactate in the cerebrospinal fluid in infectious diseases of the central nervous system by Hideraldo Luis Souza Cabeça, Hélio Rodrigues Gomes, Luís dos Ramos Machado, José Antonio Livramento

“…The concentration of lactate in the CSF was elevated in the group of patients with bacterial meningitis (average = 46.2 mg/dL), fungal meningitis (average = 27.3 mg/dL) and in the AIDS group (average = 23.5 mg/dL). …”
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Enhanced extracellular matrix remodeling due to embedded spheroid fluidization by Tao Zhang, Shabeeb Ameen, Sounok Ghosh, Kyungeun Kim, Mrinal Pandey, Brian C H Cheung, Minh Thanh, Alison E Patteson, Mingming Wu, J M Schwarz

“…The spheroid rheology-dependent effects are the result of cellular motility generating spheroid shape fluctuations. …”
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Immunotherapy targeting isoDGR‐protein damage extends lifespan in a mouse model of protein deamidation by Pazhanichamy Kalailingam, Khalilatul‐Hanisah Mohd‐Kahliab, SoFong Cam Ngan, Ranjith Iyappan, Evelin Melekh, Tian Lu, Gan Wei Zien, Bhargy Sharma, Tiannan Guo, Adam J MacNeil, Rebecca EK MacPherson, Evangelia Litsa Tsiani, Deborah D O'Leary, Kah Leong Lim, I Hsin Su, Yong‐Gui Gao, A Mark Richards, Raj N Kalaria, Christopher P Chen, Neil E McCarthy, Siu Kwan Sze

“…However, weekly injection of anti‐isoDGR mAb (1 mg/kg) was sufficient to significantly reduce isoDGR‐protein levels in body tissues, decreased pro‐inflammatory cytokine concentrations in blood plasma, improved cognition/coordination metrics, and extended the average lifespan of Pcmt1−/− mice. Mechanistically, isoDGR‐mAb mediated immune clearance of damaged isoDGR‐proteins via antibody‐dependent cellular phagocytosis (ADCP). …”
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Immunophenotyping of colon cancer for identification of potential antigens for colon cancer vaccines by Xuan Wang, Xuan Wang, Jingjiang Lai, Dawei Wang, Keyi Wei, Jing Yang

“…Based on molecular mechanisms, cellular features, and clinical characteristics, colon cancer was categorized into three immune subtypes (C1, C2, and C3) distinct from Thorsson’s pan-cancer subtypes (C1-C6) in pathway enrichment, with the C2 subtype exhibited significantly longer overall survival (OS) than C1 and C3 (median OS: C2 = 68 months vs. …”
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Examining the effect of intermittent cycling throughout a 3-h period on peripheral blood concentrations of haemopoietic stem and progenitor cells and cytolytic natural killer cells by Phoebe A. Cox, Fendi Pradana, Ella Noble, Samuel J. E. Lucas, Guy Pratt, Mark T. Drayson, Kevin Amin, Francesca A. M. Kinsella, Alex J. Wadley

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Dynamic Spectrum Coexistence of NR-V2X and Wi-Fi 6E Using Deep Reinforcement Learning by Kashish D. Shah, Dhaval K. Patel, Brijesh Soni, Siddhartan Govindasamy, Mehul S. Raval, Mukesh Zaveri

“…The deployment of 5G NR-based Cellular-V2X, i.e., the NR-V2X standard, is a promising solution to meet the increasing demand for vehicular data transmission in the low-frequency spectrum. …”
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A high-efficiency and stable transfection approach by using calcium phosphate in HEK293T cells by Kuang Ye, Fang Yourong, Liu Li, Wang Rong, Yan Ziqin, Li Hailong, Meng Fanguo, Sheng Qing, Ou Wenbin

“…Transfection, involving the transfer of exogenous DNA to eukaryocyte cells, is a common technique in molecular and cellular biology, including calcium phosphate transfection, electroporation, lipofection and so on. …”
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Improved Mechanical Performances of Hastelloy C276 Composite Coatings Reinforced with SiC by Laser Cladding by Yuqing Tang, Zheng Lu, Xuan Zhang, Xihuai Wang, Shengbin Zhao, Mingdi Wang

“…The optimal SiC addition was determined to be 9 wt%, yielding an average microhardness of 670.1 HV_0.5, which is 3.05 times that of the substrate and 1.19 times that of the 0 wt% SiC coating. …”
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Plasma galectins and metabolites in advanced head and neck carcinomas: evidence of distinct immune characteristics linked to hypopharyngeal tumors by Bao-Tram Thi Tran, Aurore Gelin, Sylvère Durand, Matthieu Texier, Amaury Daste, Clémence Toullec, Karim Benihoud, Ingrid Breuskin, Philippe Gorphe, Florence Garic, Catherine Brenner, Christophe Le Tourneau, Jérôme Fayette, Toshiro Niki, Muriel David, Pierre Busson, Caroline Even

“…Extra-cellular galectins 1, 3 and 9 (gal-1, −3 and −9) are known to act as soluble immunosuppressive agents in various malignancies. …”
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Guanine derivatives as promising candidates for the development of purine-based antimalarial drugs by Worlanyo Tashie, Harry P. de Koning, Nancy O. Duah-Quashie, Nancy O. Duah-Quashie, Neils B. Quashie, Neils B. Quashie, Neils B. Quashie

“…To understand their cellular targeting, molecular docking of the same analogues was performed using the structure of P. falciparum Equilibrative Nucleoside Transporter 1 (PfENT1). …”
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Consequences of coronavirus infection: Hemorheological disorders and possibilities for correction by Margarita V. Kruchinina, Andrei A. Gromov, Irina I. Logvinenko, Elina V. Kruchinina

“…Examined 308 patients (154 men and 154 women), average age 53.1±13.8 years, COVID-19 convalescents, within 2 to 14 months after the disease, 50 people of comparable age and gender who had not suffered COVID-19. 42 patients from the main group who had suffered coronavirus infection received complex therapy (taking the drugs Ronocit® and Cocarnit® (World Medicine Ilac San. …”
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Leukemia risk and rate of radiation dose accumulation. Part 2: Comparative analysis of leukocytic indices and dynamics of peripheral blood values in relation to external gamma-expo... by S. F. Sosnina, A. M. Yurkin, P. V. Okatenko, S. A. Rogacheva, E. A. Gruzdeva, M. E. Sokolnikov

“…Particular features of the dynamics of the cellular composition of peripheral blood can be used as indicators of pathological hematopoiesis in exposed workers prior to clinical manifestation of leukemia.…”
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PBMC transcriptome changes in beef steers with negative or positive residual feed intake following in vitro LPS stimulation by Yarahy Leal, Samanthia Johnson, Modoluwamu Idowu, Godstime Taiwo, Taylor Sidney, Emily Treon, Deborah Ologunagba, Luke M. Gratz, Olanrewaju B. Morenikeji, Ibukun M. Ogunade

“…Negative-RFI beef steers (n =8, RFI= -2.00) and positive-RFI beef steers (n = 8, RFI = +1.59) were identified from a group of 40 crossbred beef steers (average BW = 360 ± 7.3 kg) after a 56-d RFI testing period. …”
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Cerium(IV) oxide:silver/graphene oxide (CeO2:Ag/GO) nanoparticles modulate gene expression and inhibit colorectal cancer cell growth: a pathway-centric therapeutic approach by Omid Reza Tamtaji, Amirreza Ostadian, Mina Homayoonfal, Majid Nejati, Maryam Mahjoubin-Tehran, Fatemeh Nabavizadeh, Elaheh Ghelichi, Bahareh Mohammadzadeh, Merat Karimi, Neda Rahimian, Hamed Mirzaei

“…CeO2:Ag/GO NPs induced stronger growth inhibition and apoptosis in CRC cells, which was linked to their improved cellular uptake and ability to target multiple cancer-related pathways. …”
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MORPHOLOGICAL CONDITION OF THE MUCOUS DURING THE PERIOD OF PHYSIOLOGICAL CHANGE OF THE CANINES OF THE UPPER JAW by M. Cholovskyi

“…Thus, inflammatory infiltration was everywhere either diffuse or large-focal in nature and spread significantly deeper into its own plate of the mucous membrane. Among the cellular elements of the inflammatory infiltrate, neutrophilic leukocytes were quite often found, which indicate the active phase of the inflammatory process. …”
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Expanded genome and proteome reallocation in a novel, robust Bacillus coagulans strain capable of utilizing pentose and hexose sugars by David Dooley, Seunghyun Ryu, Richard J. Giannone, Jackson Edwards, Bruce S. Dien, Patricia J. Slininger, Cong T. Trinh

“…Genome sequencing revealed that B-768 has the largest B. coagulans genome known to date (3.94 Mbp), about 0.63 Mbp larger than the average genome of sequenced B. coagulans strains, with expanded carbohydrate metabolism and mobilome. …”
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Rhaponticin inhibits the proliferation, migration, and invasion of head and neck squamous cell carcinoma (HNSCC) cells through modulation of the IL6/STAT3 signaling pathway by Hongcheng Wei, Shanshan Wang, Jiayue Wan, Sicheng Li, Wei Wang, Jiajun Zhu, Lin Jiang, Yisen Shao, Yuan Wu

“…The mechanisms by which rhaponticin influences the occurrence and progression of HNSCC were investigated through network pharmacology, molecular docking, bioinformatics analysis, and cellular experiments. Result Using network pharmacology, we identified 40 hub genes from the collected gene set. …”
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Sivelestat-Loaded Neutrophil-Membrane-Coated Antioxidative Nanoparticles for Targeted Endothelial Protection in Sepsis by Juexian Wei, Aijia Zhong, Yuting Zhang, Ehua Deng, Hengzong Mo, Hongyu Zhao, Jiayu Huang, Huaidong Peng, Kaiyin Zhang, Xiaohui Chen, Haifeng Mao, Yixin Chen, Yongcheng Zhu

“…<b>Results</b>: The optimized Siv@NMs exhibited an average particle size of approximately 150 nm, and a zeta potential of −10 mV was achieved. …”
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Structural mapping of polyclonal IgG responses to HA after influenza virus vaccination or infection by André Nicolás León, Alesandra J. Rodriguez, Sara T. Richey, Alba Torrents de la Pena, Rachael M. Wolters, Abigail M. Jackson, Katherine Webb, C. Buddy Creech, Sandra Yoder, Philip A. Mudd, James E. Crowe, Julianna Han, Andrew B. Ward

“…ABSTRACT Cellular and molecular characterization of immune responses elicited by influenza virus infection and seasonal vaccination have informed efforts to improve vaccine efficacy, breadth, and longevity. …”
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Exploring research trends in cancer immunotherapy via single-cell technologies: a scientometric perspective by Zhongxun Li, Zhongxun Li, Qi Han, Qi Han, Zimu Huang, Sen Zhang, Huina Guo, Huina Guo, Hongliang Liu, Hongliang Liu, Hongliang Liu, Xiaoya Guan, Xiaoya Guan, Hairong Li, Chunming Zhang, Chunming Zhang, Chunming Zhang

“…Research hotspots focus on tumor immune microenvironment and cellular heterogeneity. Research trends such as spatial transcriptomics, standardized processes, and T cell function are becoming increasingly popular.ConclusionIn tumor immunotherapy, single-cell sequencing is profoundly changing the research paradigm. …”
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