Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography by Vineeta Das, Furu Zhang, Andrew J. Bower, Joanne Li, Tao Liu, Nancy Aguilera, Bruno Alvisio, Zhuolin Liu, Daniel X. Hammer, Johnny Tam

“…Methods Here, we introduce parallel discriminator generative adversarial network (P-GAN), an artificial intelligence (AI) method designed to recover speckle-obscured cellular features from a single AO-OCT volume, circumventing the need for acquiring a large number of volumes for averaging. …”
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Neobacillus driksii sp. nov. isolated from a Mars 2020 spacecraft assembly facility and genomic potential for lasso peptide production in Neobacillus by Asif Hameed, Francesca McDonagh, Pratyay Sengupta, Georgios Miliotis, Shobhan Karthick Muthamilselvi Sivabalan, Lukasz Szydlowski, Anna Simpson, Nitin Kumar Singh, Punchappady Devasya Rekha, Karthik Raman, Kasthuri Venkateswaran

“…N. driksii grew at 4°C to 45°C, pH range of 6.0 to 9.5, and 0.5% to 5% NaCl. The major cellular fatty acids are iso-C15:0 and anteiso-C15:0. …”
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Structural and functional state of blood lymphocytes in patients with infectious mononucleosis with different course by Ya. V. Kolesnyk, T. O. Briukhanova, M. Yu. Sliepchenko, O. A. Nakonechna, O. H. Sorokina

“…It is determined that the indicators of cellular and humoral parts of the immune system affect the course of IM. …”
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Folate-Modified Smart Responsive Nanosystems for Enhancing Anti-Tumor Therapy Through Calcium Overload and Chemotherapy by Tang Y, Huang J, Cui C, Yang F, Li K, Gao B, Fu S, Yang X

“…Cellular experiments demonstrated that the synergistic effect of tumor cell calcium overload and chemotherapy resulted in tumor cell death. …”
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Development of Chrome-Doped Hydroxyapatite in a PVA Matrix Enriched with Amoxicillin for Biomedical Applications by Steluta Carmen Ciobanu, Daniela Predoi, Simona Liliana Iconaru, Krzysztof Rokosz, Steinar Raaen, Coralia Bleotu, Mihai Valentin Predoi

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Diagnostic value of galectin-3 in heart transplant recipients with myocardial complications by O. P. Shevchenko, A. A. Ulybysheva, N. P. Mozheiko, O. E. Gichkun, E. A. Stakhanova, V. P. Vasilieva, A. O. Shevchenko

“…Their ages ranged from 16 to 71 (average 48 ± 12) years, of which 106 (85%) were men and 18 (15%) were women. …”
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Changes in Neutrophil Membranes Induced by Plasma from Newborns with Infection by V. A. Inozemtsev, I. V. Obraztsov, E. A. Sherstyukova, S. S. Kandrashina, M. A. Shvedov, M. E. Dokukin, V. A. Sergunova

“…We quantified nuclear and membrane surface areas, the intensity of neutrophil extracellular trap (NET) formation, and membrane arithmetic average roughness (Ra).Results. A standardized protocol for neutrophil preparation and evaluation was developed. …”
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A distributed hybrid model for agricultural water-land resource matching by Shufang Wang, Mohamed Khaled Salahou, Liping Wang, Honghui Sang, Shiwei Li, Yuping Lv

“…In this study, a distributed hybrid model (VIC-RCM) based on the Variable Infiltration Capacity-3Layers (VIC-3L), Random Forest Cellular Automata Markov model (RF-CA-Markov), and Global Climate Models (GCMs) was developed. …”
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Competence-based curriculum reform of Principles of Genetic Engineering in biomedical education for promoting the construction of first-class majors and disciplines: a qualitative... by Zuquan Hu, Hongmei Liu, Ying Peng, Mei Luo, Jian Peng, Xiaoyan Peng, Sha Ou, Yun Wang, Lina Zeng, Zhu Zeng

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Exploring common genomic biomarkers to disclose common drugs for the treatment of colorectal cancer and hepatocellular carcinoma with type-2 diabetes through transcriptomics analys... by Sabkat Mahmud, Alvira Ajadee, Arnob Sarker, Reaz Ahmmed, Tasfia Noor, Md Al Amin Pappu, Md Saiful Islam, Md Nurul Haque Mollah

“…Genetic association studies based on average of Log2 fold-change (aLog2FC) of cDEGs suggested a genetic association among CRC, HCC and T2D. …”
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<i>Drosophila</i> as a Model for Human Disease: Insights into Rare and Ultra-Rare Diseases by Sergio Casas-Tintó

“…Despite these advances, the average rare disease patient still experiences significant delay until receiving a diagnosis. …”
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Neuromorphic-enabled video-activated cell sorting by Weihua He, Junwen Zhu, Yongxiang Feng, Fei Liang, Kaichao You, Huichao Chai, Zhipeng Sui, Haiqing Hao, Guoqi Li, Jingjing Zhao, Lei Deng, Rong Zhao, Wenhui Wang

“…Abstract Imaging flow cytometry allows image-activated cell sorting (IACS) with enhanced feature dimensions in cellular morphology, structure, and composition. However, existing IACS frameworks suffer from the challenges of 3D information loss and processing latency dilemma in real-time sorting operation. …”
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The beneficial impacts of dietary Berberine-loaded chitosan nanoparticles on growth performance and health status of newly weaned rabbits facing heat stress by Fatma Mohsen Shalaby, Soha Ahmed Hassan, Ali A. El-Raghi, Amal El-Sayed Abd El Hady, Fatemah Enad Alajmi, Amina A. Hassan, Kandil Abd El Hai Attia

“…Through polynomial regression, the optimal doses of BER-CNPs were 50, 45, 46, and 50 mg/kg for average daily gain, feed conversion ratio, rectal temperature, and respiration rate, respectively. …”
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AI-Assisted Hypothesis Generation to Address Challenges in Cardiotoxicity Research: Simulation Study Using ChatGPT With GPT-4o by Yilan Li, Tianshu Gu, Chengyuan Yang, Minghui Li, Congyi Wang, Lan Yao, Weikuan Gu, DianJun Sun

“…ResultsChatGPT with GPT-4o generated 96 hypotheses, of which 13 (14%) were rated as highly novel and 62 (65%) as moderately novel. The average group score of 3.85 indicated a strong level of innovation in these hypotheses. …”
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Preweaning heat stress alters liver transcriptome and DNA methylation in dairy calves by Jimena Laporta, Bethany Dado-Senn, Anne R. Guadagnin, Lihe Liu, Francisco Peñagaricano

“…Providing mechanical cooling via fans to dairy calves in summer seems beneficial to promoting thermoregulation and liver cellular hemostasis.…”
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Transcriptomic profiling of gastrointestinal tracts in dairy cattle during lactation reveals molecular adaptations for milk synthesis by Yahui Gao, George E. Liu, Li Ma, Lingzhao Fang, Cong-jun Li, Ransom L. Baldwin, VI

“…In this study, we obtained a total of 108 transcriptome profiles from three tissues (epithelia of the colon, duodenum, and rumen) of five Holstein cows, spanning eight time points from the early, mid, late lactation periods to the dry period. On average 97.06% of reads were successfully mapped to the reference genome assembly ARS-UCD1.2. …”
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Options for correction of local immune status in patients with chronic endometritis by I. O. Borovikov, E. I. Kravcova, V. P. Bulgakova, O. I. Borovikova, M. I. Biryukova

“…Preimplantation preparation with intrauterine irrigation with a cavitated solution of rIL-2 in patients with recurrent implantation failures accomplished by chronic endometritis helps to improve the indices of local immunity, being more effective (an average of twofold), compared with the group of conventional preparation for IVF with thawed embryos. …”
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Comparative assessment of structural and tear film alterations in rabbit meibomian gland dysfunction models using chemical and electrocauterization techniques by Deeksha Prasad, Saumya Jakati, Kiran Kumar Bokara, Sayan Basu, Vivek Singh, Pragnya Rao Donthineni

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Development of a Graphene Oxide-Based Aptamer Nanoarray for Improved Neutralization and Protection Effects Against Ricin by Huafei Li, Yanwen Ai, Yanjin Wu, Ruyu Fan, Yuan Tian, Shuangqun Chen, Wei Wan, Cong Wu

“…Its performance was evaluated in terms of affinity for ricin, neutralization capacity, and therapeutic effects in cellular assays and a mouse model of ricin poisoning. …”
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Investigation of confocal microscopy for differentiation of renal cell carcinoma versus benign tissue. Can an optical biopsy be performed? by Michael C. Phung, Andrew R. Rouse, Jayce Pangilinan, Robert C. Bell, Erika R. Bracamonte, Sharfuddeen Mashi, Arthur F. Gmitro, Benjamin R. Lee

“…One such modality is confocal microscopy which allows in situ visualization of cells within a layer of tissue and imaging of cellular-level structures. The goal of this study is to validate the ability of confocal microscopy to quickly and accurately differentiate between normal renal tissue and cancer. …”
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