Burden, clinical outcomes, and characteristics of tuberculosis in migrant populations in the middle East and North African region: A systematic review and meta-analyses by Taha Maatoug, Farah Seedat, Eman Elafef, Anissa Ouahchi, Ali Mtiraoui, Stella Evangelidou, Wejdene Mansour, Ana Requena-Méndez, Dominik Zenner

“…Results: Of the 779 records identified, we included 57 studies, comprising 95,190 TB cases and 3,532,359 migrants across 12 MENA countries. …”
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Mental Health and Quality of Life in Patients with Untreated Unruptured Intracranial Aneurysms: A Systematic Review and Meta-Analysis of 417,152 Patients with Trial Sequential Anal... by Plamen Penchev, Kiril Ivanov, Daniela Milanova-Ilieva, Lyubomir Gaydarski, Kiril Kostov, Nikola Boyadzhiev, Petar-Preslav Petrov, Patrice Mehandzhiev, Remzi Hyusein, Vladislav Velchev, Ilko Ilyov, Valentin Kuzmanov, Gergana Dzhikova, Desislava Dobreva, Liliana Toptchiyska, Vasilena Dimitrova, Victoria Petrova, Svetoslav Yorov, Pavel Stanchev, Martin Gyulbaharov, Noor Husain, Nikolai Ramadanov

“…<b>Introduction:</b> Unruptured intracranial aneurysms (UIAs) can induce psychological stress, leading to anxiety, depression, and impaired quality of life (QoL). Most studies on this topic are limited by small sample sizes, cross-sectional designs, and a focus on treated rather than untreated cases, leaving a gap in the literature. …”
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Diagnostic accuracy of artificial intelligence for the screening of prostate cancer in biparametric magnetic resonance imaging: a systematic review by Oksana V. Kryuchkova, Elena V. Schepkina, Natalia A. Rubtsova, Boris Y. Alekseev, Anton I. Kuznetsov, Svetlana V. Epifanova, Elena V. Zarya, Ali E. Talyshinskii

“…BACKGROUND: Based on the latest published data, 40,137 new cases of prostate cancer were reported in Russia in 2021, ranking second after lung cancer in men. …”
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Levodopa / opicapone as a complement to STN-DBS in clinical practice. A retrospective single-centre analysis. by Moritz A. Loeffler, Philipp Klocke, Idil Cebi, Alireza Gharabaghi, Daniel Weiss

“…Conclusion: These results indicate a clinical phenotype characterised by more motor fluctuations requiring a more stable dopamine replacement therapy to address the patients' disease biology. In these cases, levodopa + COMT inhibition by opicapone represents a therapeutic approach but determination of the potential clinical benefit requires further prospective studies.…”
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A possible role for immunogenetic factors in myositis developing after vaccination in the pre-covid-19 era by Eaman Alhassan, Anna Patnaik, Anna Patnaik, Ejaz A. Shamim, Ejaz A. Shamim, Ejaz A. Shamim, Janardan P. Pandey, Lisa G. Rider, Frederick W. Miller, Frederick W. Miller

“…Myositis after vaccination (MAV) is a rare clinical entity, but given immunogenetic associations with other adverse events, we explored genetic risk factors, particularly human leukocyte antigen (HLA) alleles and GM/KM immunoglobulin allotypes, that may predispose individuals to develop MAV.MethodsWe examined clinical characteristics, vaccination history, autoantibodies, HLA alleles and GM/KM allotypes from 56 patients who developed MAV, 133 myositis cases with no documented vaccination within 6 months of onset (non-MAV), and 527 healthy controls from the pre-COVID-19 era. …”
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Insights from a Pseudo-Polygyny Cohort unmasking high sperm concentration and low forward motility as potential risk factors for recurrent failure of sperm donation IVF (RFDI), a s... by Tiancheng Zhang, Fan Dong, Xu Zhang, Ping Ping, Jin Qiu, Zhen Lu, Huachun Zou, Qian Xiao, Jianhui Li, Gaoyue Zhang, Huijuan Shi, Xiangfeng Chen

“…Summary: Background: Unexplained male infertility (UMI) accounts for 15%–30% of cases of male infertility, but it is poorly understood. …”
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Predictive Accuracy of a Clinical Model for Carriage of Pathogenic/Likely Pathogenic Variants in Patients with Dementia and a Positive Family History at PUMCH by Jialu Bao, Yuyue Qiu, Tianyi Wang, Li Shang, Shanshan Chu, Wei Jin, Wenjun Wang, Yuhan Jiang, Bo Li, Yixuan Huang, Bo Hou, Longze Sha, Yunfan You, Yuanheng Li, Meiqi Wu, Yutong Zou, Yifei Wang, Li Huo, Ling Qiu, Qi Xu, Feng Feng, Chenhui Mao, Liling Dong, Jing Gao

“…<b>Methods:</b> A total of 601 Chinese patients with dementia and a family history were enrolled at Peking Union Medical College Hospital, with 476 in a retrospective derivation cohort and 125 in a temporal validation cohort. …”
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Mulberry twig alkaloids for type 2 diabetes mellitus: a systematic review and meta-analysis by Guoming Chen, Ruifeng Yang, Xiaoya Yang, Jiazhen Jiang, Yudan Guo, Mengshan Xu, Yi Chen, Yining Hou, Cheng Zhang, Ning Wang, Yibin Feng

“…BackgroundDiabetes has emerged as a significant global health concern, with over 95% of cases categorized as type 2 diabetes mellitus (T2DM). …”
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Clinical Characteristics of EGPA Patients in Comparison to GPA Subgroup with Increased Blood Eosinophilia from POLVAS Registry by Anna Drynda, Agnieszka Padjas, Krzysztof Wójcik, Radosław Dziedzic, Grzegorz Biedroń, Katarzyna Wawrzycka-Adamczyk, Anna Włudarczyk, Joanna Wilańska, Jacek Musiał, Zbigniew Zdrojewski, Zenobia Czuszyńska, Anna Masiak, Maria Majdan, Radosław Jeleniewicz, Hanna Augustyniak-Bartosik, Katarzyna Jakuszko, Magdalena Krajewska, Alicja Dębska-Ślizień, Hanna Storoniak, Barbara Bułło-Piontecka, Witold Tłustochowicz, Joanna Kur-Zalewska, Małgorzata Wisłowska, Piotr Głuszko, Marta Madej, Ewa Jassem, Iwona Damps-Konstańska, Eugeniusz Kucharz, Marek Brzosko, Marcin Milchert, Anna Hawrot-Kawecka, Joanna Miłkowska-Dymanowska, Paweł Górski, Anna Lewandowska-Polak, Joanna Makowska, Joanna Zalewska, Lech Zaręba, Stanisława Bazan-Socha

“…To characterize the eosinophilic granulomatosis with polyangiitis (EGPA) population from the POLVAS registry depending on ANCA status and diagnosis onset, including their comparison with the granulomatosis with polyangiitis (GPA) subset with elevated blood eosinophilia (min. 400/μl) (GPA HE) to develop a differentiating strategy. Methods. A retrospective analysis of the POLVAS registry. …”
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Uniportal Robotic Lobectomy and Lymphadenectomy for Invasive Lung Cancer: A Novel Approach and Perioperative Outcomes by Shengcheng Lin, Xiangyang Yu, Yafei Xu, Yu Xin, Jie He, Zhentao Yu, Hongbo Zhao, Chenglin Yang, Kai Ma

“…Methods The clinical data of 34 consecutive patients with lung cancer who underwent improved uniportal robotic‐assisted thoracoscopic surgery (uRATS) at our hospital between November 2023 and June 2024 were reviewed retrospectively. …”
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Optical Imaging Demonstrates Tissue-Specific Metabolic Perturbations in Mblac1 Knockout Mice by Busenur Ceyhan, Parisa Nategh, Mehrnoosh Neghabi, Jacob A. LaMar, Shalaka Konjalwar, Peter Rodriguez, Maureen K. Hahn, Matthew Gross, Gregory Grumbar, Kenneth J. Salleng, Randy D. Blakely, Mahsa Ranji

“…Interestingly, the AD risk associated with MBLAC1 arises in subjects with cardiovascular morbidity, suggesting a broader functional insult arising from reduced MBLAC1 protein expression and one possibly linked to metabolic alterations. Methods: Our current studies, utilizing Mblac1 knockout (KO) mice, seek to determine whether mitochondrial respiration is affected in the peripheral tissues of these mice. …”
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Alteration, mineralization, geochemistry and fluid inclusion investigations in Joftrud prospect area, southwest of Birjand by Omid Shareipour, Azadeh Malekzadeh Shafaroudi, Maryam Javidi Moghaddam

“…Recently, Karjo (2021) has studied geochemistry of ore-veins in the area. For the first time, detailed studies of base metal mineralization and genesis of veins have been conducted. …”
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Effect of Benson’s relaxation training on fatigue and sleep quality of elderly patients after surgery for with glioma (本森放松训练对老年胶质瘤术后患者疲乏程度与睡眠质量的影响)... by GAO Yan (高严), HUANG Na (黄娜), DENG Lan (邓岚)

“…Objective Using Benson’s relaxation training to reduce the physical tension and anxiety of elderly patients with glioma after surgery, improve the quality of sleep, relieve fatigue, and improve the satisfaction of patients during hospitalization. Methods A total of 100 elderly glioma patients admitted to the hospital from April to October 2022 were studied. …”
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Estimation of the girls cost vaccination against human papillomavirus in the Siberian Federal District by O. A. Ananina, L. D. Zhuykova, L. A. Kolomiets, E. L. Choinzonov, G. A. Kononova, L. V. Pikalova

“…To evaluate the cost-effectiveness of HPV vaccination in girls aged 9-14 years in the Siberian Federal District as a whole and in the context of subjects with a 60, 80, 90 percent target cohort.Materials and methods. We studied the size of the female population aged 9-14 years in the constituent entities of the Siberian Federal District for 2022, the average total cost of the vaccine, information on the gross regional product per capita, form C51 “Distribution of deaths by gender, age groups and causes of death” of Tomsk region, 2022. …”
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INVESTIGATION OF IMMUNOGENICITY AND SAFETY OF 23-VALENT POLYSACCHARIDE PNEUMOCOCCAL VACCINE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS by G. M. Tarasova, B. S. Belov, D. V. Bukhanova, M. V. Cherkasova, S. K. Solovyev, E. A. Aseeva, T. M. Reshetnyak, T. V. Popkova

“…Objective: to investigate the safety and immunogenicity of 23-valent polysaccharide pneumococcal vaccine (PPV-23) in patients with systemic lupus erythematosus (SLE). Subjects and methods. The investigation enrolled 30 patients with a reliable diagnosis of SLE; of them there were 27 women and 3 men at the age of 19 to 62 years. …”
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Single-round performance of colorectal cancer screening programs: a network meta-analysis of randomized clinical trials by Teruhiko Terasawa, Toshihiro Tadano, Koichiro Abe, Seiju Sasaki, Satoyo Hosono, Takafumi Katayama, Keika Hoshi, Tomio Nakayama, Chisato Hamashima

“…FIT-based programs likely detect more AN cases than gFOBT-based programs, while FS-, CTC-, and TCS-based programs may outperform FIT. …”
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Predictors of therapeutic failure in GH and prolactin co-secreting pituitary adenomas by Marta Araujo-Castro, Betina Biagetti, Edelmiro Menéndez, Iría Novoa-Testa, Fernando Cordido, Víctor Rodríguez Berrocal, Eider Pascual-Corrales, Fernando Guerrero-Pérez, Almudena Vicente, Rogelio García-Centeno, Laura González, María Dolores Ollero García, Ana Irigaray Echarri, María Dolores Moure Rodríguez, Cristina Novo-Rodríguez, María Calatayud, Rocío Villar-Taibo, Ignacio Bernabéu, Cristina Alvarez-Escola, Carmen Tenorio Jimenéz, Pablo Abellán-Galiana, Eva Venegas, Inmaculada González-Molero, Pedro Iglesias, Concepción Blanco, Fernando Vidal-Ostos De Lara, María Paz de Miguel Novoa, Elena López-Mezquita Torres, Felicia Hanzu, Cristina Lamas, Silvia Aznar Rodríguez, Anna Aulinas, José María Recio, María Dolores Aviles-Pérez, Miguel Antonio Sampedro Núñez, Rosa Camara, Miguel Paja Fano, Carmen Fajardo, Luís Cardoso, Pedro Marques, Elena Martínez-Sáez, Ignacio Ruz-Caracuel, Mónica Marazuela, Manel Puig-Domingo

“…Aim: To evaluate which factors are associated with a higher probability of failure to surgical and first-generation somatostatin receptor ligands (fgSRLs) treatment in patients with growth hormone and prolactin co-secreting pituitary adenomas (GH&PRL-PAs). Methods: Acromegaly patients with GH&PRL-PAs included in the ACRO-SPAIN study were enrolled. …”
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Meta-analyses of IL1A polymorphisms and the risk of several autoimmune diseases published in databases. by Hang Su, Na Rei, Lei Zhang, Jiaxiang Cheng

“…<h4>Background</h4>Based on published data, we aimed to quantitatively elucidate the possible genetic influence of rs17561 G/T and rs1800587 C/T polymorphisms of the IL1A (interleukin 1 alpha) gene in the susceptibility to several autoimmune diseases.<h4>Methods</h4>A series of meta-analyses were carried out. …”
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Pulsed-field ablation of atrial fibrillation with a pentaspline catheter across National Health Service England centres by Tom Wong, Mark T Mills, Shajil Chalil, Francis Murgatroyd, Scott Gall, Aruna Arujuna, David Jones, Mark O'Neill, Claire Martin, Zhong Chen, Shui Hao Chin, Dhiraj Gupta, Derick M Todd, Sarah Zeriouh, Greg Mellor, Vishal Luther, Richard Balasubramaniam, Mark Sopher, Matthew J Lovell, Riyaz Somani, Peter Calvert, Riyaz A Kaba, Saket Trivedi, Julian Boullin, Magdi Saba, Una Buckley

“…In first-time ablation cases, acute isolation of all pulmonary veins was achieved in 99.5% of patients. …”
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Efficacy and safety of neoadjuvant PD-1 inhibitors or PD-L1 inhibitors combined with chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis by Jiaojiao Yu, Jiaojiao Yu, Zhijing Wang, Mingxu Li, Hua Zhu, Xiaoxia Tang, Ke Luan, Yinhuan Zhi, Shan Yin, Yuanqi Su, Jingyan Long, Qubo He, Jieru Quan, Chenchen Li, Chenchen Li, Chenchen Li, Chenchen Li

“…BackgroundThe objective of this meta-analysis was to assess the effectiveness and safety of neoadjuvant PD-1/L1 inhibitors plus chemoradiotherapy(CRT) for locally advanced rectal cancer (LARC).Materials and MethodsDatabases including PubMed, Embase, Cochrane Library and Web of Science were examined for pertinent studies. …”
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