Cytokine status in patients with sepsis by S. D. Shapoval, I. L. Savon, O. V. Trybushnyi, O. O. Maksymova, M. M. Sofilkanych

“…The aim of the work is to find out the dynamics of changes in the most important cytokines in patients with sepsis caused by diabetic foot syndrome. Materials and methods. A total of 146 patients with sepsis who received treatment in the Zaporizhzhia Purulent-Septic Center with diabetic foot beds between 2006 and 2019 were examined and followed up. …”
Get full text

Single-center register of myocardial revascularization in patients with coronary artery disease and acute coronary syndrome in the context of COVID-19 pandemic by O. V. Kamenskaya, A. S. Klinkova, I. Yu. Loginova, V. N. Lomivorotov, A. M. Chernyavskiy, V. V. Lomivorotov

“…To assess the short- and long-term outcomes of myocardial re- vascularization (MR) in patients with coronary artery disease (CAD) and acute coronary syndrome (ACS) in the context of coronavirus disease 2019 (COVID-19) pandemic.Material and methods. In the period from April to August 2020, 550 patients with CAD and ACS were included in the register. …”
Get full text

Broadening the Phenotype Spectrum of MECP2 Variants in Men by Johannes Lötjönen, Venla Kurra, Hannele Laivuori, Nina Bjelogrlić

“…We describe the clinical picture of two brothers carrying the same MECP2 variant and compare them with cases published in the literature. Methods Most of the MECP2 mutations are known to be de novo mutations, which is why the recurrence of the mutation in the couple's other children is unlikely. …”
Get full text

Stillbirth and fetal growth restriction by V. G. Volkov, M. V. Kastor

“…Aim: to estimate the rate of early-onset and late-onset fetal growth restriction (FGR) in stillbirth, identify features of placentaassociated complications and determine respective risk factors of stillbirth (especially at early gestational age).Materials and Methods. There were retrospectively studied 61 stillbirth cases in 2016–2019 that occurred in the III level obstetric hospitals: 32 early (23–31 weeks of gestation) and late (32–39 weeks) cases; 156 live births with 8–10 Apgar scores delivered at 36–41 weeks of gestation used as controls. …”
Get full text

Prognostic and clinicopathological significance of the Controlling Nutritional Status (CONUT) score in patients with lymphoma: a meta-analysis by Lili Li, Lihong Shou

“…The relationship between CONUT and clinicopathological characteristics was measured based on pooled ORs with 95% CIs.Data sources PubMed, Web of Science, Embase and Cochrane Library databases were comprehensively searched from inception through 24 March 2023.Statistical methods Either a random-effects model or a fixed-effects model was selected depending on the level of heterogeneity among the included studies.Results This meta-analysis enrolled seven articles, containing 2060 patients with lymphoma. …”
Get full text

The Burden of Human Metapneumovirus (hMPV) Disease in Older and High-Risk Adults in Developed Countries: A Systematic Literature Review by Ajoke Sobanjo-ter Meulen, Aura V. Gutierrez, Ornella Ruiz, Jennifer Eeuwijk, Hilde Vroling, Niranjan Kanesa-thasan

“…We conducted a critical review of published evidence on the burden of hMPV in older adults and adults with comorbidities. Methods Articles reporting the burden of hMPV disease in adults ⩾50 years or ⩾18 years with comorbidities in developed countries were searched in Embase and MEDLINE (1/January/2000–12/June/2023) databases. …”
Get full text

DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa by Uppala Radhakrishna, Uppala Ratnamala, Devendrasinh D. Jhala, Lavanya V. Uppala, Aaren Vedangi, Nazia Saiyed, Sushma R. Shah, Maulikkumar Patel, Rakesh M. Rawal, Tommaso Mazza, Gregor B. E. Jemec, Gianluigi Mazzoccoli, Giovanni Damiani, Giovanni Damiani

Get full text

The impact of comprehensive local therapy on treatment outcomes of non-small cell lung cancer with solitary skeletal oligometastasis by Jia-nan Jin, Zheng-bo Song, Wen-xian Wang, Yi Li, Shi-yan Wu

“…The value of comprehensive local therapy (CLT) for NSCLC with solitary skeletal oligometastasis remains to be established. Methods: Data on NSCLC cases with solitary skeletal oligometastasis were collected retrospectively between August 2008 and March 2022. …”
Get full text

Antibiotic resistant Shigella is a major cause of diarrhoea in the Highlands of Papua New Guinea by Andrew R Greenhill, Carlton Guwada, Valentine Siba, Audrey Michael, Mition Yoannes, Yolandah Wawarie, Rebecca Ford, Peter M Siba, Paul F Horwood

“…., Campylobacter spp. and Yersinia enterocolitica using established culture methods. Enteric parasites were detected using microscopy. …”
Get full text

ASAP1 Promotes Epithelial to Mesenchymal Transition by Activating the TGFβ Pathway in Papillary Thyroid Cancer by Shiji Song, Zixing Leng, Xinxin Zhao, Ziping Liu, Yongshuai Li, Wenjing Zhang, Junming Yue, Yuxia Fan

“…However, its role in PTC remains unclear. Methods ASAP1 expression in PTC was evaluated using TCGA and GEO databases. …”
Get full text

Radiation therapist (RTT) perspectives on developing image-guided radiotherapy (IGRT) protocols for reirradiation by Aileen Duffton, Lynsey Devlin, Aoife Williamson, Derek Grose, Eilidh Tolmie, Linda MacLaren, Sharon McFadden, Rebecca Muirhead

“…The aim of this work was to identify ways to optimise reirradiation IGRT protocols based on RTT feedback. Methods: A quantitative and qualitative service improvement approach was selected, using a plan, do, check approach. …”
Get full text

Single-Center Outcomes of Autologous Hematopoietic Stem Cell Transplantation Accompanied by High-Dose Chemotherapy in Patients with Solid Organ Tumors by Levent Ündar, Ozan Salim, Sema Sezgin Göksu, Utku Iltar, Ünal Ataş, Orhan Kemal Yücel, Ayşe Tan Doğruel

“…Aim: In contrast to hematologic diseases, the use of hematopoietic stem cell transplantation (HCT) for solid organ tumors is limited, with recommendations available only for certain selected diagnoses and cases. Methods: Data from 16 adult patients who underwent HCT with a diagnosis of solid organ tumor between 2006-2023 were analyzed.Results: The median age of the patients was 36.5 years (21–46), and 13 (81.2%) were male. …”
Get full text

The consequences of micro-discretions and boundaries in the social prescribing link worker role in England: a realist evaluation by Stephanie Tierney, Debra Westlake, Geoffrey Wong, Amadea Turk, Steven Markham, Jordan Gorenberg, Joanne Reeve, Caroline Mitchell, Kerryn Husk, Sabi Redwood, Anthony Meacock, Catherine Pope, Kamal R Mahtani

“…We studied seven link workers based in different parts of England. …”
Get full text

Effects of Grout Defects on Seismic Behavior of Precast Concrete Shear Wall by ZHENG Wei, ZHANG Shiqian, MA Minglei, YIN Guanghua, CHEN Shaojun

“…The seismic behavior of precast concrete shear wall with grout defects were analyzed. This paper study the effect of sleeve grouting defects on the seismic performance of precast concrete shear wall, and provides a reference for the performance evaluation and subsequent treatment of sleeve grouting defects.MethodsSeven prefabricated concrete shear walls (six test specimens with grouting defects and one test specimen with full grouting) connected by reinforcement sleeve grouting were designed for low cycle repeated loading tests. …”
Get full text

The economic burden of migraine: a nationwide cost-of-illness approach from the year 2020 European Health Survey in Spain by J. Fernández-Ferro, C. Ordás-Bandera, J. Rejas-Gutiérrez, B. Ferro-Rey, S. Gómez-Lus, J.M. Láinez Andrés

“…Methods: The nationwide year-2020 European-Health-Survey-in-Spain was used; 1442 persons with migraine (77.3% women, 52.5 years) and 4288 without migraine (76.7% women, 52.8 years) were abstracted by propensity score optimal matching. …”
Get full text

Functional Status in Elderly Kidney Transplant Recipients: A Systematic Review Evaluating Physical Function, Frailty, and Cognitive Impairment as Predictors of Post-Transplant Outc... by Hachem Araji, Yazan A. Al-Ajlouni, Jana Nusier, Walid Sange, Elie El-Charabaty, Suzanne El-Sayegh

“…This systematic review examines the influence of frailty, physical functionality, and cognitive function on outcomes in elderly kidney transplant recipients. Methods: Adhering to PRISMA guidelines, a rigorous literature search was conducted across PubMed, CINAHL, Embase, PsycINFO, and the Web of Science for studies published up to October 31, 2024. …”
Get full text

Recalibrating the kidney failure risk equation for a Mediterranean European population: reducing age and sex inequality by Daniel Bundó-Luque, Daniel Bundó-Luque, Daniel Bundó-Luque, Oriol Cunillera-Puértolas, Oriol Cunillera-Puértolas, Sílvia Cobo-Guerrero, Sílvia Cobo-Guerrero, José Romano, José Romano, Ariadna Arbiol-Roca, Ariadna Arbiol-Roca, José Alberto Domínguez-Alonso, José Alberto Domínguez-Alonso, Josep Maria Cruzado, Josep Maria Cruzado, Josep Maria Cruzado, Betlem Salvador-González, Betlem Salvador-González

“…Additionally, we recalibrate KFRE-4 for predicting KF, including all patients reaching CKD stage 5, not just those on RRT.MethodsRetrospective cohort study including individuals aged ≥50 years with confirmed glomerular filtration rate (eGFR) <60 mL/min/1.73m2 and measured albumin-to-creatinine ratio (ACR). …”
Get full text

Combined use of olfactory mucosal mesenchymal stem cells conditioned medium and neural guide conduits promotes nerve regeneration in an ovine model by Rui Alvites, Rui Alvites, Rui Alvites, Rui Alvites, Bruna Lopes, Bruna Lopes, Bruna Lopes, André Coelho, André Coelho, André Coelho, Ana Catarina Sousa, Ana Catarina Sousa, Ana Catarina Sousa, Patrícia Sousa, Patrícia Sousa, Patrícia Sousa, Alícia Moreira, Alícia Moreira, Alícia Moreira, Alexandra Rêma, Alexandra Rêma, Alexandra Rêma, Maria Simões, Maria Simões, Maria Simões, Maria Simões, Carla Mendonça, Carla Mendonça, Carla Mendonça, Luís Atayde, Luís Atayde, Luís Atayde, Justina Prada, Justina Prada, Justina Prada, Isabel Pires, Isabel Pires, Isabel Pires, Bruna Silva, Bruna Silva, Filipa João, Miriam Metafune, Francesca Bertone, Stefania Raimondo, Nuno Alves, Nuno Alves, Nuno Alves, Ana Lúcia Luís, Ana Lúcia Luís, Ana Lúcia Luís, Ana Colette Maurício, Ana Colette Maurício, Ana Colette Maurício

“…IntroductionPeripheral nerve injuries remain a significant clinical challenge, particularly in severe neurotmesis injuries requiring complex therapeutic interventions to restore functionality. This study aimed to evaluate the pro-regenerative potential of combining neural guide conduits with conditioned medium from olfactory mucosa mesenchymal stem cells, compared to gold-standard surgical techniques.MethodsThe study was conducted using a validated ovine model of common peroneal nerve injury. …”
Get full text

Trends in HPV‐associated cancer incidence in Texas medically underserved regions by Thao N. Hoang, Abbey B. Berenson, Yong Shan, Fangjian Guo, Victor Adekanmbi, Christine Hsu, Xiaoying Yu, Yong‐Fang Kuo

“…Methods Cancer data from 2006 to 2019 were obtained from the TX Cancer Registry. …”
Get full text

A new classification for dislocated and displaced proximal humeral fractures by Sadaki Mitsuzawa, Hisataka Takeuchi, Kenta Ijiri, Yuya Furusho, Shinnosuke Yamashita, Yoshihiro Tsukamoto, Satoshi Ota, Eijiro Onishi, Tadashi Yasuda

“…We developed an entirely new classification, the Mitsuzawa classification, for dislocated and displaced proximal humeral fractures and tested all three classifications for their intra- and interobserver reliability. Methods Two experienced shoulder surgeons and two orthopedic residents independently evaluated the Xray (xR) values of 100 proximal humeral fractures (PHFs). …”
Get full text