Reduced p63 expression is linked to unfavourable prognosis in muscle‐invasive urothelial carcinoma of the bladder by Kira Furlano, Henning Plage, Sebastian Hofbauer, Sarah Weinberger, Bernhard Ralla, Annika Fendler, Florian Roßner, Simon Schallenberg, Sefer Elezkurtaj, Martina Kluth, Maximilian Lennartz, Niclas C. Blessin, Andreas H. Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Stefan Koch, Nico Adamini, Sarah Minner, Ronald Simon, Guido Sauter, Joachim Weischenfeldt, Tobias Klatte, Thorsten Schlomm, David Horst, Henrik Zecha

“…Recently proposed RNA expression‐based molecular classifiers of bladder cancer identified high p63 expression as a component of a basal/squamous subtype linked to poor patient prognosis. Methods In this study, p63 protein expression was analysed by immunohistochemistry on more than 2500 urothelial bladder carcinomas in a tissue microarray format to determine its relationship with clinicopathological parameters of disease progression and patient outcome. …”
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Epidemiology of autoimmune encephalitis and comparison to infectious causes—Experience from a tertiary center by Yahel Segal, Ofer Rotschild, Yair Mina, Gadi Maayan Eshed, Tal Levinson, Yael Paran, Michal Dekel, Ronit Cohen‐Poradosu, Adi Ashkenazi, Itamar Moreno, Orna Aizenstein, Ora Halutz, Yifat Alcalay, Avi Gadoth

“…Methods All encephalitis cases, aged 18 and above, admitted to TASMC between the years 2010 and 2020 were reviewed for demographic, clinical, laboratory, and imaging data and categorized based on etiology. …”
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Anatomical Variables of the Superior Thyroid Artery on Computed Tomography Angiograms by Rodica Narcisa Calotă, Mugurel Constantin Rusu, Marius Ioan Rusu, Cătălin Constantin Dumitru, Alexandra Diana Vrapciu

“…We aimed to determine the topographic variants of the STA related to the GHHB and the artery of origin and to check their bilateral symmetry. <i>Materials and Methods:</i> Determinations were performed in a sample of 85 archived angio CT adult cases, comprising 53 men and 32 women. …”
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Review of treatment modalities and clinical outcome of giant saccular posterior cerebral artery aneurysms by Andreas Theofanopoulos, Rajiv Kumar Khajuria, Dilaware Khan, Lucas Troude, Ben Waldau, Katharina Faust, Sajjad Muhammad

“…Research question: To review treatment modalities and outcomes of patients harboring giant (>2.5 cm) PCA saccular aneurysms distal to the basilar bifurcation. Materials and methods: A systematic literature review through PubMed and Scopus to identify cases of giant saccular PCA aneurysms treated either microsurgically or endovascularly. …”
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Evaluation of 99Tcm-DTPA orbit SPECT/CT combined with thyroid function test in the treatment of radioactive iodine I-131 in patients with thyroid-associated ophthalmopathy-hyperthy... by Su Li, Mi Ping, Niu Wenqiang, Zhou Ting, Yang Wang, Chen Cheng, Huang Chenggang

“…This research evaluated the efficacy of 99Tcm-DTPA orbital SPECT/CT combined with thyroid function test in radioactive iodine I-131 (RAI) treatment of TAO-hyperthyroidism. Methods: We retrospectively studied clinical activity score (CAS), blood thyrotropine (TSH), free triiodothyronine (FT3), free thyroxine (FT4), thickness of extra-ocular muscle (EOM), and uptake rate (UR) of 99Tcm-DTPA orbital SPECT/CT of 43 patients after 6 months of treatment with 20 mCi RAI. …”
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Global epidemiology and socioeconomic correlates of hypopharyngeal cancer in 2020 and its projection to 2040: findings from GLOBOCAN 2020 by Seyed Ehsan Mousavi, Seyed Ehsan Mousavi, Mehran Ilaghi, Yasaman Mirzazadeh, Alireza Mosavi Jarrahi, Alireza Mosavi Jarrahi, Seyed Aria Nejadghaderi, Seyed Aria Nejadghaderi

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Innovations in Minimally Invasive Management of Esophageal Atresia and Tracheoesophageal Fistula by Adrian Surd, Rodica Muresan, Carmen Iulia Ciongradi, Lucia Maria Sur, Lia Oxana Usatiuc, Kriszta Snakovszki, Camelia Munteanu, Ioan Sârbu

“…Objective: This narrative review provides a comprehensive overview of the evolution and current status of MIS techniques for EA/TEF, assessing their clinical outcomes, technical challenges, and implications for patient care. Methods: A structured literature search was conducted to identify clinical studies, reviews, and reports on thoracoscopic, robotic-assisted, and endoscopic approaches to EA/TEF. …”
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The Spectrum and Frequency of Inner Ear Anomalies in Patients with Congenital Hearing Impairment in Yakutia by L. A. Klarov, N. A. Barashkov, F. M. Teryutin, G. P. Romanov, M. M. Popov, A. V. Solov’ev, N. V. Luginov, A. V. Tobokhov, P. M. Kotlyarov

“…To analyze the spectrum and frequency of inner ear anomalies in patients with congenital hearing impairment in Yakutia.Material and methods. A total of 165 patients with congenital hearing impairment were surveyed. …”
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<i>Mycobacterium Ulcerans</i> Ulcer: Current Trends in Antimicrobial Management and Reconstructive Surgical Strategies by Bryan Lim, Omar Shadid, Jennifer Novo, Yi Mon, Ishith Seth, Gianluca Marcaccini, Roberto Cuomo, Daniel P. O’Brien, Warren M. Rozen

“…Surgical interventions in select cases are crucial, with timing being a significant factor in functional outcomes. …”
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Onychomycosis Endonyx: A Systematic Review by Ernesto De-La-Rosa-Garibay, Roberto Arenas, Martha Y. Herrera-Castro, Alicia Valdez-Gaona, Gabriela Moreno-Coutiño, Paola Berenice Zarate-Segura, Fernando Bastida-González, Erick Martínez-Herrera, Rodolfo Pinto-Almazán

“…The other 47.3% of the studies lacked a traceable criterion for the diagnosis of these cases. …”
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A systematic review of the effects of housing support on social welfare outcomes in pregnancy and early childhood by Kathleen Brew, Jessica Heerde, Anna Price, Karen McLean

“…Participants: and setting: Provision of housing support for clients experiencing homelessness while pregnant or parenting young children (0–7 years) in high-income countries. Methods: A systematic search of databases CINAHL and SocIndex for peer reviewed studies, with independent double-screening of retrieved studies and full-text review of eligible studies. …”
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Advancing Bilateral Limbal Deficiency Surgery: A Comprehensive Review of Innovations with Mucosal Cells by Zahra Bibak-Bejandi, Mohammad Soleimani, Zohreh Arabpour, Emine Esra Karaca, Elmira Jalilian, Hassan Asadigandomani, Reyhaneh Bibak-Bejandi, Ali R. D’jalilian

“…Besides alternative surgical methods for bilateral limbal deficiency, such as KLAL (keratolimbal allograft), living-related conjunctival limbal allograft (LR-CLAL), and keratoprosthesis, regenerative medicine often necessitates the use of alternative sources of limbal cells in cases where access to fellow eye source cells is limited. …”
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Experience with nusinersen as a pathogenetic therapy in adult patients with spinal muscular atrophy 5q in the Republic of Bashkortostan by S. V. Umutbaev, L. Sh. Murzabaeva, M. A. Kutlubaev, A. V. Shishigin, T. N. Sharipov, E. V. Sayfullina, R. V. Мagzhanov

“…To analyze the experience of using nusinersen as a pathogenetic therapy for patients over 18 years of age with SMA 5q in the Republic of Bashkortostan.Materials and methods. We examined eight patients receiving pathogenetic therapy with nusinersen (SMA type 2 – 34.5 %, SMA type 3 – 65.5 %). …”
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Copy Number Variation Analysis in Turkish Patients with Congenital Bilateral Absence of Vas Deferens by Semra Kahraman, Mehmet Murad Başar, Yiğit Akın, Durkadın Demir Ekşi, Elanur Yılmaz, Mustafa Faruk Usta, Munire Erman, Özgül M. Alper

“…According to the literature, up to 88% of CBAVD cases have at least one pathogenic Cystic Fibrosis Transmembrane Conductance Regulator gene (CFTR) mutation. …”
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Delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: a narrative review by Ingrid Pereira Marques, Carolina Rouanet Cavalcanti de Albuquerque, Natalia Vasconcellos de Oliveira Souza, João Brainer Clares de Andrade, Gisele Sampaio Silva, Pedro Kurtz

“…This is more pronounced in high-grade aSAH patients who are unconscious or sedated. In such cases, additional methods may be necessary, such as transcranial Doppler (TCD), continuous electroencephalography (cEEG), or CT with perfusion (CTP). …”
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Adjuvant Second-Dose Chemotherapy before Surgery for Patients with Locally Advanced Rectal Malignancy Is Not Beneficial: A Systematic Review and Meta-Analysis by Min Chen, Xue Song, Liang-zhou Chen, Lin Xu, Yi-pu Lu, Jin-song Zhang

“…Controversy exists with regard to the efficacy of different preoperative combination chemotherapy regimens and neoadjuvant chemoradiotherapy, compared with chemoradiotherapy alone. Methods. PubMed, the Cochrane Library, and Embase databases were searched for comparative studies of patients with locally advanced rectal cancer that were published between January 1991 and January 2016. …”
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High diversity of Escherichia coli causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approach by Oliver Pearse, Allan Zuza, Edith Tewesa, Patricia Siyabu, Alice J. Fraser, Jennifer Cornick, Kondwani Kawaza, Patrick Musicha, Nicholas R. Thomson, Nicholas A. Feasey, Eva Heinz

“…We describe the genomic characteristics of a collection of neonatal E. coli isolates from a tertiary hospital in Blantyre, Malawi, with specific reference to potential protection by vaccines under development. Methods Neonatal blood or cerebrospinal fluid cultures from 2012 to 2021 identified 208 E. coli isolates, and 169 could be recovered for sequencing. …”
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Treatment of biliodigestive anastomotic strictures after transplantation of left lateral segment of the liver by A. R. Monakhov, B. L. Mironkov, M. A. Voskanov, S. V. Meshcheryakov, E. T. Azoev, K. O. Semash, T. A. Dzhanbekov, O. V. Silina, S. V. Gautier

“…Many studies have shown that biliary complications after transplantation of the left lateral segment (LLS) of the liver reduce graft and recipient survival. …”
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Secure and efficient cloudlet networks: blockchain integration with agent-based proof of trust mechanism by Nothile C. Masango, Jeffrey O. Agushaka, Mercy C. Amaefule, Olutosin Taiwo, Peiying Zhang, Absalom E. Ezugwu, Kashif Saleem, Aseel Smerat, Laith Abualigah

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Mutated Adenovirus Attacks in West Bengal, India: Risk Evaluation of Multi‐Country Outbreaks and Mitigation Strategies by Md. Ashrafur Rahman, Sydney Cronmiller, Julianne Ernest, Jonah Nguyen, Donovan Zong, Rob Davis, Amanda Rawa, Marie Roke Thomas, Rana Al Mosharrafa, Yeasna Shanjana, Md. Rabiul Islam

“…ABSTRACT Aim The human adenovirus (HAdV) is beginning to spread rapidly in children through human, surface and animal vectors. Around 12,000 cases were recognised in 2022 in West Bengal and a shocking number of cases arose throughout India and in other under‐developed areas. …”
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