COMPARATIVE ANALYSIS OF THE SEMIOTICS OF DISSEMINATED PULMONARY TUBERCULOSIS AND EXOGENOUS ALLERGIC ALVEOLITIS IN ACCORDANCE WITH THE DATA OF COMPUTED TOMOGRAPHY by R. B. Amansakhedov, I. V. Limarova, A. V. Perfiliev, R. Yu. Abdullaev, A. T. Sigaev, A. E. Ergeshov

“…Objective: to improve the differential diagnosis of disseminated pulmonary tuberculosis (DPT) and exogenous allergic alveolitis (EAA) via comparative investigation of their computed tomography (CT) semiotics and identification of the most informative diagnostic criteria. Material and methods. 70 patients, including 40 patients with DPT in a phase of infiltration and 30 patients with acute EAA, were studied using a Somatom Emotion 16 multi-slice spiral CT scanner (Siemens). …”
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Abstract 219: Determining the Proportion of Patients with Poor Premorbid mRS presenting with Large Volume Stroke by Madheea Siddiqi

“…Cases presenting with ASPECTS<6 as assigned by a neuroradiologist were identified. …”
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A rare germline mutation reverses the suppressive effect of GPC5 thereby promoting lung adenocarcinoma development and tumorigenesis by Zhifa Zheng, Zhifa Zheng, Zhifa Zheng, Zhifa Zheng, Lina Zhao, Lina Zhao, Lina Zhao, Lina Zhao, Sen Zhao, Zhihong Wu, Zhihong Wu, Zhihong Wu, Nan Wu, Nan Wu, Nan Wu

“…Background and ObjectiveGlypican-5 (GPC5) has been well-characterized as a tumor suppressor in lung adenocarcinoma (LUAD); however, the functional implications of its germline mutations in cancer pathogenesis remain largely unexplored. In this study, we identified and characterized a pathogenic GPC5 variant (c.776C&gt;T, p.Pro259Leu) within a Chinese LUAD pedigree, systematically investigating its oncogenic mechanisms through comprehensive molecular and cellular analyses.MethodsOur investigation employed a multifaceted approach beginning with the recruitment of a LUAD-affected family cohort (n=4 patients, 1 healthy control), followed by exome sequencing of matched blood and FFPE tumor samples. …”
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A systematic review and functional in-silico analysis of genes and variants associated with amyotrophic lateral sclerosis by Carlos A. Arreola-Aldape, Carlos A. Arreola-Aldape, Carlos A. Arreola-Aldape, Jose A. Moran-Guerrero, Jose A. Moran-Guerrero, Guillermo K. Pons-Monnier, Guillermo K. Pons-Monnier, Rogelio E. Flores-Salcido, Rogelio E. Flores-Salcido, Emmanuel Martinez-Ledesma, Emmanuel Martinez-Ledesma, Luis M. Ruiz-Manriquez, Luis M. Ruiz-Manriquez, K. Rebeca Razo-Alvarez, K. Rebeca Razo-Alvarez, Daniela Mares-Custodio, Daniela Mares-Custodio, Pablo J. Avalos-Montes, Pablo J. Avalos-Montes, Jose A. Figueroa-Sanchez, Jose A. Figueroa-Sanchez, Rocio Ortiz-Lopez, Rocio Ortiz-Lopez, Rocio Ortiz-Lopez, Hector R. Martínez, Hector R. Martínez, Raquel Cuevas-Diaz Duran, Raquel Cuevas-Diaz Duran

“…However, there is considerable phenotypic heterogeneity, and its diagnosis is based on clinical criteria. Moreover, most ALS cases remain unexplained, suggesting a complex genetic background.MethodsTo better understand the molecular mechanisms underlying ALS, we comprehensively analyzed, filtered and classified genes from 4,293 abstracts retrieved from PubMed, 7,343 variants from ClinVar, and 33 study accessions from GWAS catalog. …”
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Combined Cataract and Vitrectomy Surgery in Pediatric Patients by Armando J. Ruiz-Justiz, Vanessa Cruz-Villegas, Stephen G. Schwartz, Victor M. Villegas, Timothy G. Murray

“…<i>Purpose:</i> To review the current literature on the combined use of cataract surgery (or lensectomy) and vitrectomy in pediatric patients, with a focus on clinical indications, surgical techniques, outcomes, and complications across various pediatric ocular pathologies. <i>Methods:</i> A narrative review of published studies addressing the use of combined lensectomy and vitrectomy (LV) in pediatric patients was conducted. …”
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Evidence of pathogens associated with travelers’ diarrhea in Thailand: a systematic review by Wanida Mala, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Kinley Wangdi, Polrat Wilairatana, Manas Kotepui

“…Abstract Background Thailand, a major tourist destination, exhibits variations in sanitation and food safety practices that can lead to cases of travelers’ diarrhea (TD) caused by a plethora of pathogens. …”
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Thymol and carvacrol against Klebsiella: anti-bacterial, anti-biofilm, and synergistic activities—a systematic review by Kousha Farhadi, Erta Rajabi, Hesam Aldin Varpaei, Maryam Iranzadasl, Sepideh Khodaparast, Mohammadreza Salehi

“…This review aims to illustrate the potential antimicrobial, anti-biofilm, and synergistic traits of thymol and carvacrol in combat against Klebsiella.MethodsSearching PubMed, Scopus, and Web of Science, we reviewed available evidence on the antibacterial effects of thymol, carvacrol, or combined with other compounds against Klebsiella until May 2024. …”
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Natural history of progressive vision loss in Bietti crystalline dystrophy: a model-based meta-analysis by Wenbin Wei, Qingshan Zheng, Ning Guan, Haihan Zhang, Shiyi Yin, Jinyuan Wang, Qingqing Cheng, Lingxiao Zhang, Hua Lv

“…Then, based on the final model, the natural disease progression characteristics of BCD were simulated.Result A total of 14 studies met the inclusion criteria, with a total sample size of 117 cases, including 6 studies (N=80) with East Asian populations and 9 studies (N=37) with non-East Asian populations. …”
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Preliminary Evaluation of the Safety and Immunogenicity of an Antimalarial Vaccine Candidate Modified Peptide (IMPIPS) Mixture in a Murine Model by Jennifer Lambraño, Hernando Curtidor, Catalina Avendaño, Diana Díaz-Arévalo, Leonardo Roa, Magnolia Vanegas, Manuel E. Patarroyo, Manuel A. Patarroyo

“…In spite of great efforts aimed at developing better prevention (i.e., a highly effective vaccine), diagnosis, and treatment methods for malaria, no efficient solution to this disease has been advanced to date. …”
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Efficacy of membranectomy for the treatment of chronic subdural hematoma: an updated meta-analysis by Ibraheem M. Alkhawaldeh, Mariam Abdelhady, Ahmed Aljabali, Ibrahim Serag, Hadeer Elsaeed AboElfarh, Rowan H. Elhalag, Abdulhameed Alhadeethi, Muhammad Ashraf Husain, Jenan A. Alkasasbeh, Mohamed Abouzid

“…This meta-analysis aimed to determine the benefits of Membranectomy when performed in conjunction with other neurosurgical interventions. Methods A systematic search was conducted in four electronic databases (PubMed, Cochrane Library, Web of Science, and Scopus) for eligible comparative studies until January 2024. …”
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Exclusive breastfeeding as a cornerstone for the survival and health of newborns: Sociocultural, economic, and structural influences among Indigenous Pygmy women by BAFUTANGA Emmanuel KUMBOYO, MOTOBA jean NOMUOMBANE, KUMBOTULU jeancy MISUNGU, MATATA César Fataki, MUAZUBA Florence Ambengi, Marie-Claire Ohambe Omanyondo, BASUA Félicien Mukandu

“…Purpose To analyze the sociocultural, economic, and health determinants of exclusive breastfeeding among Indigenous Pygmy women and identify barriers and strategies for improvement. Methods A systematic search was conducted in scientific databases (PubMed, Scopus, Google Scholar) to identify studies published between 2020 and 2024. …”
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The road less travelled: Skeletal muscle invasion in oral squamous cell carcinoma by Shreya Chatterjee, Anju Devi, Mala Kamboj, Anjali Narwal, Rahul Anand, Ridhi Bhola

“…Amalgamation of mitotic count and skeletal muscle invasion can put forward cogent paths in discerning the behavior of these lesions. Material &amp; methods: A total of 60 histopathologically diagnosed cases of well, moderately and poorly-differentiated OSCC cases were obtained from the archives. …”
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The efficacy of Tujia Ningxin Anmian pillow combined with auricular acupoint sticking therapy in patients with chronic heart failure complicated by sleep disorders (土家宁心安眠枕联合耳穴贴压在慢... by LONG Guimei (龙贵梅), HUANG Jia (黄佳), WU Xian (吴献), MA Chunqin (麻春琴), PENG Yanhua (彭燕华), TIAN Ru (田汝)

“…Objective To explore the effects of Tujia Ningxin Anmian pillow combined with auricular acupoint pressing on sleep quality and cardiac function in patients with chronic heart failure (CHF) accompanied by sleep disorders. Methods A total of fifty CHF patients with sleep disorders were selected and randomly divided into a control group and an observation group, with 25 cases in each group. …”
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Morphofunctional retinal pigment epithelium changes in normal eye and age-related macular degeneration by R.R. Fayzrakhmanov, E.D. Bosov, V.A. Bogdanova, E.E. Vaganova, O.L. Sechina

“…To analyze features of retinal pigment epithelium in normal and pathological conditions. Material and methods. The literature review was carried out using PubMed and Sochape Library. …”
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Pharmacoeconomic Evaluation of Using One-Molar Gadolinium-Based Magnetic Resonance Contrast Agent Compared to Half-Molar Agents for the Diagnosis of Multiple Sclerosis by A. A. Alikhanov, N. L. Shimanovskiy

“…The analysis of pharmacoeconomic effectiveness showed that magnetic resonance studies of the central nervous system using gadobutrol were characterized by a reduction in the number of MS exacerbations by 70 cases. …”
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Skeletal and dental effects of skeletally anchored forsus fatigue resistant devices during class II malocclusion treatment: A meta-analysis and systematic review by Osama Eissa, Samira Diar-Bakirly, Humam Saltaji, Tarek El-Bialy

“…MATERIALS AND METHODS: Unrestricted electronic search of six databases and additional manual searches were performed up to July 2023. …”
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Title not available by João Aris Kouyoumdjian, Erik Stålberg

“…Objective:To estimate jitter parameters in myasthenia gravis in stimulated frontalis and extensor digitorum muscles using the concentric needle electrode.Methods:Forty-two confirmed myasthenia gravis patients, being 22 males (aged 45.6&#177;17.2 years-old) were studied. …”
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Endothelial damage and complement dysregulation in fetuses from pregnancies complicated by preeclampsia by Alex Ramos, Lina Youssef, Patricia Molina, Julia Martinez‐Sanchez, Ana Belen Moreno‐Castaño, Miquel Blasco, Blanca De Moner, Marta Tortajada, Marta Camacho, Maria Borrell, Francesca Crovetto, Marc Pino, Gines Escolar, Enric Carreras, Eduard Gratacos, Maribel Diaz‐Ricart, Marta Palomo, Fatima Crispi

“…Abstract Introduction Our objective was to evaluate the endothelial function profile and complement system in fetuses from preeclamptic pregnancies using ex vivo and in vitro approaches. Material and Methods A total of 66 singleton pregnancies were prospectively recruited comprising 34 cases of preeclampsia and 32 normotensive pregnancies matched for baseline characteristics. …”
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Investigating Family History Status, Frequency of BRCA1/BRCA2 Mutations and Molecular Subtypes of Breast Cancer in the Highly Consanguineous Eastern Saudi Arabia Population: Implic... by Tahani Al-Qurashi, Sarah Balghonaim, Kanza Rashid, Haya Albunyan, Hattan Alduhailan, Latiffah Almqhawi, Irtaza Fatima Zafar, Rehab Abubaker, Anees R Malik, Hani Mustafa, Yaqob Samir Taleb, Tariq Karar, Nawaf Alanazi, Abdulkareem Al-Garni, Sarah Al-mukhaylid, Zafar Iqbal

“…Given the high frequency of consanguineous marriages in this less urbanized area, we hypothesized an increase in family history and involvement of recessive genes, but lower frequencies of BRCA1/BRCA2 mutations in BC genes. Methods and Results: The study included 115 patients diagnosed with BC at King Abdulaziz Hospital, Al-Ahsa, between 2007 and 2022. …”
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Mucinous Ovarian Carcinoma: Integrating Molecular Stratification into Surgical and Therapeutic Management by Mauro Francesco Pio Maiorano, Brigida Anna Maiorano, Gennaro Cormio, Vera Loizzi

“…This review aims to integrate current evidence on the clinical management of MOC with emerging insights into its molecular biology, with a focus on how these factors influence surgical decision-making, fertility preservation, and adjuvant therapy selection. <b>Methods</b>: We performed a comprehensive narrative review of the literature, synthesizing findings from retrospective cohorts, molecular studies, and clinical guidelines relevant to the surgical, reproductive, and therapeutic management of MOC. …”
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