Surgical Management of Retroperitoneal Liposarcoma: Opportunities for Multimodality Treatment, Including Systemic Therapy by Steven Sun, Kenneth Cardona, William W. Tseng

“…The purpose of this review is to outline surgical management of RP LPS and highlight the multimodal treatment strategies for both primary and recurrent disease, along with considerations for their effective implementation. Methods The current medical literature was reviewed for studies focused on retroperitoneal liposarcoma and its treatment with surgery, radiation, and chemotherapy. …”
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DISTINGUISHING MEDIATED PERFORMANCE OF A CRIMINAL OFFENSE AND COMPLICATION IN A CRIMINAL OFFENSE by Oleh Omelchuk, Viktor Zakharchuk

“…The concept of such mediated performance was studied, its system was defined, and typical methods of its execution were characterized. …”
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The Good, the Bad, and the Epigenetic: Stress-Induced Metabolite Regulation and Transgenerational Effects by Saida Ibragić, Sabina Dahija, Erna Karalija

“…Recent research has revealed that these stress-induced metabolic processes are tightly regulated by epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs. Methods: This review synthesizes current findings from studies on both model and crop plants, examining the roles of key epigenetic regulators in controlling secondary metabolism under stress. …”
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A South Indian Journey on the Trivialized Healthcare Menace of Adverse Drug Reactions by Aneesha PK, Rakesh Raghavakurup, Archa Fenn, Aleena Sunny

“…Introduction:The primary objective is to encourage HCPs to report more ADRs by bringing out data on the incidence, rate and characteristics of ADRs, ADR-related hospital admissions and by exposing their impact on patient outcomes.Materials and Methods: This was a record-based retrospective cross-sectional analysis undertaken to investigate ADR monitoring and reporting in a tertiary care hospital. …”
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OPTIMAL SEQUENCE OF APPLICATION OF EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORS IN ADVANCED NON-SMALL CELL LUNG CANCER PATIENTS WITH ACTIVATING EGFR MUTATIONS by A. A. Kolomeytseva, A. A. Fedenko

“…The issue of what drug or what sequence of its administration will be the optimal treatment option for a particular patient seems relevant.Purpose: To analyze available data on the use of TKIs for the treatment of advanced EG FR-positive NSCLC patients, as well as to assess the possible mechanisms of resistance to them and determine the optimal sequence of EG FR TKI therapy.Material and Methods. The review includes data from randomized controlled trials, as well as data from real-world studies on the efficacy of EG FR TKIs and subsequent therapy options in cases of drug resistance.Results. …”
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HLA-DQA1*04:01 is related to a higher multiple sclerosis lesion load on T2/Flair MRI sequences by Fabio NORO, Soniza Vieira ALVES-LEON, Fabricia Lima FONTES-DANTAS, Paulo Roberto VALLE BAHIA, Rodrigo Ferrone ANDREIUOLO, Fernanda Cristina RUEDA LOPES, Valeria Coelho Santa Rita PEREIRA, Livia de Almeida Afonso ABI-HAILA, Renan Amaral COUTINHO, Amanda Dutra de ARAUJO, Edson MARCHIORI

“…Objective: To identify associations between findings in magnetic resonance imaging (MRI) and genetic features in a Brazilian cohort of patients with MS. Methods: We retrospectively studied data from 95 consecutive patients with MS. …”
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Causes of Uncertain Chemotherapy Outcomes in Patients with Pulmonary Tuberculosis Treated in Penitentiary Institutions of the Russian Federation by S. N. Lisovskiy, M. E. Vostroknutov, Yu. V. Mikhaylova, S. A. Sterlikov, S. B. Ponomarev

“…Reporting of the «transferred out» outcome leads to significantly worse treatment results of tuberculosis patients treated in the institutions of the Federal Penitentiary Service of Russia.The objective: to investigate the patients’ routes that led to reporting of the «transferred out» outcome, and propose measures to reduce the risk of this outcome.Subjects and Methods. We studied the places of registration and routes of 1,496 pulmonary tuberculosis patients registered for treatment in 2019 (new cases and relapses) with the outcome of «transfered out».Results. …”
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Systematic Review of Outcomes of Omental Free Flap in the Management of Lymphedema by Fizzah Arif, MBBS, Nida Sehar, MBBS, Bareera Ahmed Mian, MBBS, Safdar Ali Shaikh, FCPS (Plast), Mohammad Fazlur Rahman, FCPS (Plast)

“…However, it is unpopular due to the technicalities and the possibility of donor site–related abdominal complications during its harvest. Methods:. A systematic review was conducted on March 24, 2024, using PubMed, Scopus, and Ovid MEDLINE databases. …”
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Optimizing Mean Arterial Pressure Targets for Septic Shock Patients With Chronic Hypertension: A Narrative Review by Mutaz I. Othman, Emad M. Mustafa, Ahmed E. Abdelwahab, Ali A. Hssain, Abdulqadir J. Nashwan

“…Guidelines suggest 65‐75 mmHg for most cases, but higher targets may be beneficial for proper organ perfusion. …”
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RADIATION DIAGNOSIS OF RARE FORMS OF RESPIRATORY ORGAN SARCOIDOSIS by A. A. Speranskaya, O. P. Baranova, M. A. Vasilyeva, I. V. Amosov

“…Objective: to evaluate the clinical and radiological features of rare forms of sarcoidosis of the respiratory organs (SRO).Material and methods. In 2006 to 2016, the Research Institute of Interstitial and Orphan Lung Diseases followed up 599 patients with sarcoidosis. 36 patients (6.0%) of them had atypical clinical and radiation manifestations that did not correspond to the traditional radiation pattern and the existing X-ray classification of SRO. …”
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Burkholderia cepacia complex bacteremia outbreaks among non-cystic fibrosis patients in the pediatric unit of a university hospital by Sinan Tüfekci, Birol Şafak, Burçin Nalbantoğlu, Nedim Samancı, Nuri Kiraz

“…Methods. We analyzed data from six patients hospitalized at our center. …”
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An assessment of landscape‐ecological stability in agricultural regions of Ural and West Siberia by A. A. Chibilyov (jr.), Yu. A. Gulyanov, D. S. Meleshkin, D. V. Grigorevsky

“…It rises with the reduction of a tillage area in 74% of cases studied. Withdrawal from cultivation of unstable and degraded lands during the intensification of agriculture in highly fertile areas and transfer to fodder lands (including protected areas), which contribute to an increase in the proportion of stable landscape elements, can be considered as the main direction for increasing their stability and preserving biological diversity.…”
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The Management of Hisbah (Accountability) in the Crisis of Bankruptcy in Islamic Economic Law by Muhammad Sadeqi, Sobhan Abbaspour

“…For the bankruptcy private laws in most cases have been legislated in order to preserve the rights of creditors and less it refers to support business activities. …”
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Conventional and Conformal Radiotherapy with and without Beam Intensity Modulation in Patients with Stage II Hodgkin’s Lymphoma with Supradiaphragmal Lesions by YuN Vinogradova, EI Ivanova, AI Chumachenko, EV Smirnova, GI Andreev, AM Kalesnik, NA Vorob’ev, NV Il’in

“…The mean age was 30.9 years (range 18–65); the study group included 107 men and 210 women. The diagnosis in all the cases was confirmed by immunomorphologic analysis. …”
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Incidence and mortality trends of stroke and its subtypes among residents in China from 1990 to 2021: an analysis of GBD 2021 data by Wenjiao DONG, Fengxia LAI, Yao LING, Zhimei JIN, Hao CHEN, Danli KONG, Yuanlin DING

“…ObjectiveTo analyze the trends in incidence and mortality of stroke, including ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH), among Chinese residents from 1990 to 2021, and to provide a reference for stroke prevention and control strategies in China. MethodsData on the incidence and mortality of stroke, IS, ICH, and SAH among Chinese residents in 1990 and 2021 were obtained from the Global Burden of Disease (GBD) 2021 study. …”
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NAVIGATION AIDS AS TOOLS TO SUPPORT THE DEVELOPMENT OF COMPETENCES IN THE CONDITIONS OF REALIZATION OF INDIVIDUAL EDUCATIONAL TRAJECTORY by E. F. Zeer, E. Yu. Zhurlova

“…Navigators of educational process and cases of individual educational achievements assessment act as didactic means in model. …”
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Application of dicarbamin in treatment of patients by a chronic hepatitis C by D. Yu. Konstantinov, Ye. A. Konstantinova, L. L. Popova, E. A. Strebkova, A. A. Suzdaltsev

“…Aim of investigation. Studying of clinical and laboratory efficacy of dicarbamin as hematoprotector in patients with chronic hepatitis C (CHC) with 1b virus genotype at combined antiviral therapy (AVT) by pegilated interferons in combination to ribavirin.Material and methods. …”
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Retroelement co-option disrupts the cancer transcriptional programme by Jane Loong, Rachael Thompson, Callum Hall, Laura Doglio, Judith Pape, Tobias Plowman, George Kassiotis

“…These were subsequently verified in test cases by further analysis of transcriptional profiles in cancer patient data, and by in vitro studies involving restoration of gene activity, and proliferation and migration assays in cancer cell lines. …”
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Ferroptosis-Related Long Noncoding RNAs as Prognostic Marker for Colon Adenocarcinoma by Yuting Qiu, Haobo Li, Qian Zhang, Xinwei Qiao, Jing Wu

“…Methods. Gene-sequencing and clinical data for COAD were obtained from The Cancer Genome Atlas database. …”
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Inferior Alveolar Nerve Lateralization and Transposition for Dental Implant Placement. Part II: a Systematic Review of Neurosensory Complications by Boris Abayev, Gintaras Juodzbalys

“…The aim of this article is to review the scientific literature and clinical reports in order to analyse the neurosensory complications, risks and disadvantages of lateralization/transposition of the inferior alveolar nerve followed by implant placement in an edentulous atrophic posterior mandible. Material and Methods: A comprehensive review of the current literature was conducted according to the PRISMA guidelines by accessing the NCBI PubMed and PMC databases, as well as academic sites and books. …”
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