Iron Deficiency in Female Endurance Athletes: The Role of Hepcidin Regulation, Training Load, and Dietary Strategies in Optimizing Performance and Health by Małgorzata Wasilewska, Krzysztof Pietrzak, Sebastian Polok, Łukasz Bialic

“… Purpose: Examine iron deficiency (ID) mechanisms in female endurance athletes, focusing on hepcidin dysregulation, training impacts, and dietary strategies.  Materials and Methods: Systematic review of 30 years of research on IL-6/hepcidin pathways, menstrual iron loss, supplementation (oral/IV), and dietary iron bioavailability. …”
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Effects of virtual reality technology on balance function for older adults living in nursing homes: Meta analysis by Shu Jiaojiao, Xiarepa·Abudula, Halimire·Abudujilili, Yang Ruiqi, Asiguli·Tuersun, Ayisha·Jilili, Zhang Jing, Palida·Maimaiti

“…[Results] Finally, 14 studies were included with a total sample size of 588 cases. …”
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Reliability of the Grading System for Voiding Cystourethrograms in the Management of Vesicoureteral Reflux: An Interrater Comparison by Süleyman Çelebi, Seyithan Özaydın, Cemile Beşik Baştaş, Özgür Kuzdan, Cankat Erdoğan, Mehmet Yazıcı, İsmail Caymaz, Serdar Sander

“…Here, we assessed the effectiveness of the current VUR grading system. Methods. A series of 40 voiding cystourethrogram (VCUG) studies were selected. …”
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Impact of Cancer Subtype and Cancer Therapy Exposures on SARS‐CoV‐2 Outcomes in the Omicron and Subvariant Era by Katelyn M. Atkins, Minhao Wang, Katrina D. Silos, Sandy Y. Joung, Asneh Singh, Olivia Peony, Jordan O. Gasho, Yeran Lee, Kenia Gastelum, Beatrice Alessandra Filart, Alan C. Kwan, Marilyn Mendez, Yunxian Liu, Patrick Belen, John C. Prostko, Edwin C. Frias, Joseph E. Ebinger, Sonia Sharma, Kimia Sobhani, Susan Cheng

“…ABSTRACT Introduction Amidst highly transmissible SARS‐CoV‐2 variants that continue to circulate in the community, individuals with cancer exhibit variations in immunity and susceptibility for reasons that remain poorly understood. Methods In a longitudinal cohort study with ongoing SARS‐CoV‐2 serological and outcomes surveillance, we examined adults receiving cancer treatment (cases, n = 229) or who were free of cancer and other major comorbidities (controls, n = 800), prior to the Omicron era onset and onwards (September 24, 2021–March 10, 2024). …”
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Long-Term Results of Cabergoline Add-on Long-Acting Somatostatin Analogue Therapy in Acromegaly Patients by Mehmet Muhittin Yalçın, Gizem Bedir Keser, Meriç Coşkun, Afruz Babayeva, Emrah Çeltikçi, Mehmet Arda İnan, Emetullah Cindil, Aylar Poyraz, Ethem Turgay Cerit, Alev Eroğlu Altınova, Müjde Aktürk, Füsun Baloş Törüner, Mehmet Ayhan Karakoç, İlhan Yetkin

“…Objective: To investigate the efficacy of the dopamine agonist cabergoline in uncontrolled acromegaly despite long-acting somatostatin analog (SSA). Methods: Thirty-five patients with acromegaly who were followed up in the department of endocrinology and metabolism of our university were analyzed. …”
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Hybrid epithelial-mesenchymal status of lung cancer dictates metastatic success through differential interaction with NK cells by Ugo Pastorino, Massimo Milione, Paola Orecchia, Massimo Moro, Gabriella Sozzi, Monica Parodi, Giovanni Centonze, Fabio Murianni, Francesca Andriani, Ilaria Roato, Cecilia Gardelli, Melissa Balsamo, Giulia Taiè, Andrea Petretto, Chiara Lavarello ‎, Luca Roz, Massimo Vitale, Giulia Bertolini

“…Here we characterize the pro-metastatic mechanics of non-small cell lung cancer (NSCLC) H-cells and their subset of cancer-initiating cells (CICs), dissecting crucial interactions with NK cells.Methods Human lung cancer cell lines and sublines representative of E, M, or H states, assessed by proteomics, were analyzed in vivo for their tumor-forming and disseminating capabilities. …”
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Self-monitoring of blood pressure following a stroke or transient ischaemic attack (TASMIN5S): a randomised controlled trial by R. J. McManus, A. Smith, E. Temple, L. M. Yu, J. Allen, R. Doogue, G. A. Ford, L. Glynn, B. Guthrie, P. Hall, L. Hinton, F. D. R. Hobbs, J. Mant, B. McKinstry, G. Mead, K. Morton, T. Rai, C. Rice, C. Roman, A. Stoddart, L. Tarassenko, C. Velardo, M. Williams, L. Yardley, on behalf of the TASMIN5S investigators

“…This trial aimed to determine whether self-monitoring of hypertension with telemonitoring and a treatment escalation protocol, results in lower BP than usual care in people with previous stroke or transient ischaemic attack (TIA). Methods Unblinded randomised controlled trial, comparing a BP telemonitoring-based intervention with control (usual care) for hypertension management in 12 primary care practices in England. …”
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NSAID exposure delays time-to-pregnancy in patients with spondyloarthritis: an analysis of the GR2 prospective cohort by Beatrice Banneville, Arsène Mekinian, Jérémie Sellam, François Goffinet, Maxime Dougados, Eric Hachulla, Nathalie Costedoat-Chalumeau, Laure Gossec, Anna Molto, Frédéric Lioté, Emmanuel Maheu, Amélie Denis, Anne-Sophie Korganow, Christelle Sordet, Emmanuelle Dernis, Martin Soubrier, Xavier Mariette, Christophe Richez, Benjamin Chaigne, Hubert Marotte, Laurent Perard, Olivier Fain, Nicolas Schleinitz, Patrick Jégo, Elisabeth Pasquier, Sabine Berthier, Claire Grange, Marc Lambert, Jonathan London, Hélène Maillard, François Maurier, Alexis Régent, Vincent Sobanski, Grégory Pugnet, Emmanuel Chatelus, Jacques Morel, Rene-Marc Flipo, Emanuelle Dernis, Alban Deroux, Marc Fabre, Marion Couderc, Nihal Martis, Martin Michaud, Raphaele Seror, Sophie Georgin-Lavialle, Léa Savey, Hervé Levesque, Jean-Loup Pennaforte, Rakiba Belkhir, Maria Letizia Urban, Sandra Desouches, Elisabeth Gervais, Augustin Latourte, Aline Frazier, Sabrina Hamroun, Matthieu Mahevas, Bertrand Godeau, Marc Michel, Cédric Lukas, Pascal Cathébras, Geoffrey Urbanski, Holy Bezanahary, Cecile Yelnik, Ygal Benhamou, Thierry Thomas, Nicolas Martin-Silva, Gaëlle Leroux, Veronique Le Guern, Claire Larroche, Azeddine Dellal, Guillaume Moulis, Emilie Berthoux, Fleur Cohen, Guillaume Direz, Nicole Ferreira-Maldent, Antoine Froissart, Vincent Langlois, Agnès Portier, Mélanie Roriz, Boris Bienvenu, Alice Berezne, Claire Cazalets, Aurelie Hummel, Pascal Coquerelle, Laurence Loeuillet, Noémie Jourde-Chiche, Claire Blanchard-Delaunay, Moez Jallouli, Cristina Belizna, Isabelle Durieu, Gaëlle Guettrot-Imbert, Catherine Deneux-Tharaux, Elisabeth Elefant, Laetitia Dunogeant, Anne Gompel, Lisa Biale, Agathe Masseau, Elodie Chauvet, Juliette Delforge, Christian Lavigne, Marie-Agnès Timsit, Delphine Lariviere, Evangeline Pillebout, Antoinette Perlat, Jean-Maxime Piot, Vassilis Tsatsaris, Mathilde de Menthon, Claire de Moreuil, Gaetan Sauvetre, Loïc Raffray, Jeremy Ora, Celine Lartigau-Roussin, Nathalie Tieulé, Sara Melboucy-Belkhir, Antoine Baudet, Constance Beaudouin-Bazire, Anne Calas, Olivia Chandesris, Jérémy Chatelais, Marine Driessen, Aurélie Du Thanh, Cécile Durant, Phillipe Goupille, Constance Guillaud-Danis, Stéphane Jobard, Laurence Josselin-Mahr, Thomas Le Gallou, Valentine Loustau, Hélène Petit Bauer, Vincent Poindron Geneviève Plu-Bureau, Jeremy Sellam, Katia Stankovic-Stojanovic

“…Background The impact of disease activity and treatment on fertility outcomes in patients with spondyloarthritis (SpA) has been little explored. This study aimed to describe median time to pregnancy (TTP) in women with SpA and the factors influencing TTP in this population.Methods This prospective observational multicentre (63 centres) French cohort (GR2 study—NCT02450396) included consecutive women with a diagnosis of SpA (according to their rheumatologist) who wanted to become pregnant between 2015 and 2021. …”
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Distinct Profiles of CD163-Positive Macrophages in Idiopathic Interstitial Pneumonias by Masahiro Yamashita, Ryoko Saito, Shinji Yasuhira, Yuh Fukuda, Hironobu Sasamo, Tamotsu Sugai, Kohei Yamauchi, Makoto Maemondo

“…The types of cells most significantly linked to individual subtypes of idiopathic interstitial pneumonias (IIPs) remain unclear. Few studies have examined CD163+ macrophages in IIPs. …”
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Mendelian randomization analyses support causal relationship between brain imaging-derived phenotypes and risk of low back pain by Xiao-Yan Xie, Jian-Wei Lin, Jia-Yu Fang, Zhuo-Chen Chen, Peng-Cheng Li, Xiao-Yan Huang, Ming-Yan Guo, Li-Ling Lin, Ming-Hui Cao

“…Inverse variance weighted (IVW) was used as the primary MR analysis method. The MR Egger, Weighted median, Simple mode, Weighted mode, MR-RAPS, BWMR were supplemented. …”
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Reduced-dose chemotherapy followed by blinatumomab for newly diagnosed philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia: a propensity-matched comparis... by Jing Lu, Yu Zhu, Huiying Qiu, Ying Wang, Xin Zhou, Haiping Dai, Xuzhang Lu, Bin Gu, Ming Hong, Miao Miao, Ruinan Lu, Jun Wang, Qian Wu, Mengxing Xue, Yun Wang, Ailing Deng, Yaoyao Shen, Yin Liu, Xueqing Dou, Yutian Lei, Xiaofei Yang, Suning Chen

“…Methods In this retrospective study, 35 newly diagnosed Ph-negative BCP-ALL patients received reduced-dose chemotherapy followed by two weeks of blinatumomab (RDC-Blinatumomab-2W) as part of our previous clinical trial. …”
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Clinical features of the course of infective endocarditis of prosthetic valves and endocarditis of intracardiac devices by V. A. Mosina, I. V. Demko, L. I. Pelinovskaya, A. E. Ryazanov, Ya. I. Verigo, K. V. Kochkina, K. F. Kasymova

“…Both endocarditis are associated with difficulties in diagnosis, treatment and poor prognosis, which makes it relevant to analyze the clinical manifestations of these forms of endocarditis, especially in comparison with the results of other studies.Objective. To identify the features of clinical manifestations of infective endocarditis of prosthetic valves and endocarditis of intracardiac devices.Materials and methods. …”
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Treatment Of Schizophrenia With Cobenfy (KarXT): A Literature Review by Laura Kurczoba, Karolina Skonieczna, Magdalena Badziąg, Paulina Szulc, Martyna Kłossowska, Olimpia Wiciun, Olga Kądziołka, Kacper Ordon

“…The purpose of this literature review is to introduce the new psychotropic drug, discuss the mechanism of action, and present the results of the EMERGENT-1, EMERGENT-2 and EMERGENT-3 clinical trials. Materials and methods: The authors conducted an extensive review of articles available in PubMed and Google Scholar. …”
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Promising Biotechnological Applications of the Artificial Derivatives Designed and Constructed from Plant microRNA Genes by T. N. Erokhina, Ekaterina V. Ryabukhina, Irina S. Lyapina, Dmitry Y. Ryazantsev, Sergey K. Zavriev, Sergey Y. Morozov

“…Gene silencing by artificial microRNAs (amiRNAs) is one of the potential crucial methods for the regulation of desired genes to improve horticultural plants. …”
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The compliance of specialized medical care of patients with glaucoma to clinical recommendations (CR 96/1 “Primary open-angle glaucoma”) in Russian Federation regions by V. V. Neroev, T. N. Malishevskaya, M. P. Kharlampidi, L. A. Mikhaylova, S. Yu. Petrov, A. V. Zolotarev, A. Zh. Fursova, G. V. Simonenko

“…Practically in all regions of the Russian Federation, diagnostic methods and conservative/surgical treatment techniques with proven high efficiency conform to CR 96/1 “Primary open-angle glaucoma”. …”
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Clinical Usefulness of the Serological Gastric Biopsy for the Diagnosis of Chronic Autoimmune Gastritis by Antonio Antico, Marilina Tampoia, Danilo Villalta, Elio Tonutti, Renato Tozzoli, Nicola Bizzaro

“…To assess the predictive value for chronic autoimmune gastritis (AIG) of the combined assay of anti-parietal-cell antibodies (PCA), anti-intrinsic-factor antibodies (IFA), anti-Helicobacter pylori (Hp) antibodies, and measurement of blood gastrin. Methods. We studied 181 consecutive patients with anemia, due to iron deficiency resistant to oral replacement therapy or to vitamin B12 deficiency. …”
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Comparative of metagenomic and targeted next-generation sequencing in lower respiratory tract fungal infections by Zhiyang Chen, Zhiyang Chen, Zhiyang Chen, Xin Liu, Xin Liu, Xin Liu, Li Tan, Li Tan, Li Tan, Xing Lyu, Xing Lyu, Xing Lyu, Qichen Long, Qichen Long, Qichen Long, Weimin Wu, Weimin Wu, Weimin Wu, Zhe Guo, Zhe Guo, Zhe Guo, Zhenni Liu, Zhenni Liu, Zhenni Liu, Ziyang Li, Ziyang Li, Ziyang Li, Min Hu, Min Hu, Min Hu

“…ObjectivesThis study aims to compare the diagnostic efficiency and consistency of metagenomic next-generation sequencing (mNGS) and targeted next-generation sequencing (tNGS) in patients with lower respiratory tract fungal infections.MethodsA total of 115 patients with probable pulmonary infection between September 2022 and April 2023 were enrolled at the Second Xiangya Hospital, Changsha, China, of which 61 were clinically diagnosed with invasive pulmonary fungal infection (IPFI) and 54 were non-IPFI cases. …”
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A Review of the Use of Data Analytics to Address Preeclampsia in Ecuador Between 2020 and 2024 by Franklin Parrales-Bravo, Lorenzo Cevallos-Torres, Leonel Vasquez-Cevallos, Rosangela Caicedo-Quiroz, Roberto Tolozano-Benites, Víctor Gómez-Rodríguez

“…Emphasis is placed on the statistical methods used, main findings, and the technological capabilities of the facilities where the analyses were performed. …”
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Biodiverse coffee plantations provide co‐benefits without compromising yield by Dale R. Wright, Ascelin Gordon, Ruth E. Bennett, Matthew J. Selinske, Pia E. Lentini, Georgia E. Garrard, Amanda D. Rodewald, Sarah A. Bekessy

“…Of the 16 cases that investigated pollinators and yield, 85% showed a positive relationship. …”
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Thermoguided technique of lipolysis and skin retraction with 980nm diode laser by Fabio Kamamoto, Orlando Ferrari Neto, Juliana Oliveira Gomes Reis, Carla Eunice Chineze Santos, Thomas Miliou

“…The current parameters (power and energy) in the devices allow only an indirect inference of skin temperature change. Methods: Eighty-three patients, between 17 and 75 years old, were submitted to laser lipolysis with 980nm diode, using a Flir® T540 thermocamera for temperature monitoring. …”
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