MODIFICATION OF MYOCARDIUM FUNCTION AND PERFUSION AFTER LIVER TRANSPLANTATION. RESULTS OF MYOCARDIAL SCINTIGRAPHY by Y.O. Malinovskaya, E.N. Ostroumov, E.D. Kotina, Y.G. Moysyuk

“…Aim evaluated function and perfusion of myocardium in 12 cirrhotic patients before and after liver transplantation (LT).Materials and methods. ECG-gated single photon emission computed tomography (SPECT) was used.Results. …”
Get full text

Early versus delayed enteral nutrition in critically ill children under 12 years of age: A systematic review and meta-analysis of randomised controlled trials by Marianne E. Visser, Roselyn Chipojola, Sarah Gordon, Amanda Brand, Nyanyiwe Mbeye, Gertrude Kunje, Talitha Mpando, Suzgika Lakudzala, Elodie Besnier, Celeste E. Naude

“…This systematic review aimed to assess the effects of early enteral nutrition (EEN) compared to delayed enteral nutrition (DEN) in critically ill children as part of the Global Evidence, Local Adaptation (GELA) project. Methods: We searched PubMed, Embase and two trial registries (January 2000–November 2023) and included randomised controlled trials (RCTs) comparing EEN (typically within 24–48 hours of admission) to DEN (typically >48 hours of admission) in children aged one month to 12 years, and excluding studies in children with severe acute malnutrition, or conditions requiring long-term EN. …”
Get full text

Streptococcus pneumoniae serotype distribution in Bangladeshi under-fives with community-acquired pneumonia pre-10-valent pneumococcal conjugate vaccination by Stefan M. T. Vestjens, Suzan P. van Mens, Bob Meek, Tariq A. Lalmahomed, Ben de Jong, Doli Goswami, Bart J. M. Vlaminckx, Dilruba Ahmed, Bartelt M. de Jongh, Hubert P. Endtz, W. Abdullah Brooks, Ger T. Rijkers

“…Conclusions In almost a third of the studied cases S. pneumoniae was identified as a causative pathogen. …”
Get full text

Diffusion tensor MR imaging evaluation of the corpus callosum of patients with multiple sclerosis Avaliação do corpo caloso em pacientes com esclerose múltipla através de imagens d... by Fernanda Rueda, Luiz Celso Hygino Jr, Romeu Cortês Domingues, Cláudia C. Vasconcelos, Regina M. Papais-Alvarenga, Emerson L. Gasparetto

“…OBJECTIVE: To evaluate the fractional anisotropy (FA) values of the normal-appearing white matter of the corpus callosum (CC) in patients with relapsing-remitting multiple sclerosis (MS). METHOD: Fifty-seven patients with diagnosis of relapsing-remitting MS and 47 age- and gender-matched controls were studied. …”
Get full text

Predictors of Recurrence After Curative Surgery for Stage I Colon Cancer: Retrospective Cohort Analysis of the Italian Society of Surgical Oncology Colorectal Cancer Network Collab... by Giulia Turri, MD, Luigi Martinelli, MD, Daniela Rega, MD, Nicolò Tamini, MD, Lucia Paiano, MD, Simona Deidda, MD, QuocRiccardo Bao, MD, Laura Lorenzon, MD, PhD, Raffaele De Luca, MD, Caterina Foppa, MD, PhD, Valentina Mari, MD, Giovanni Taffurelli, MD, Arcangelo Picciariello, MD, PhD, Patrizia Marsanic, MD, Leandro Siragusa, MD, Francesco Bagolini, MD, Riccardo Nascimbeni, MD, Gianluca Rizzo, MD, PhD, Sara Vertaldi, MD, Michele Zuolo, MD, Giorgio Bianchi, MD, Lisa Marie Rorato, MD, Rossella Reddavid, MD, PhD, Gaetano Gallo, MD, PhD, Lorenzo Crepaz, MD, Alberto Di Leo, MD, Mario Trompetto, MD, Enrico Potenza, MD, Mauro Santarelli, MD, Nicola de’Angelis, MD, PhD, Francesco Ciarleglio, MD, Marco Milone, MD, PhD, Claudio Coco, MD, Guido Alberto Tiberio, MD, Gabriele Anania, MD, Giuseppe S. Sica, MD, PhD, Andrea Muratore, MD, Donato Francesco Altomare, MD, Isacco Montroni, MD, PhD, Maurizio De Luca, MD, Antonino Spinelli, MD, PhD, Michele Simone, MD, Roberto Persiani, MD, Gaya Spolverato, MD, Angelo Restivo, MD, Nicolò de Manzini, MD, Marco Braga, MD, Paolo Delrio, MD, Giuseppe Verlato, MD, PhD, Corrado Pedrazzani, MD, Adriana Gioia, Cristina Vacca, Dario Parini, Giovanni Tomasicchio, Marcello Calabrò, Bruno Sensi, Filomena Misuriello, Carlo Alberto Schena, Silvia Picotto

“…However, data on the actual incidence, risk factors, and site of recurrences are scarce. Methods:. This is a retrospective multicenter cohort study considering patients who underwent surgery at 25 Italian centers between 2010 and 2019, with a minimum follow-up of 24 months. …”
Get full text

An immunoinformatics approach in designing high-coverage mRNA multi-epitope vaccine against multivariant SARS-CoV-2 by Ernawati Arifin Giri-Rachman, Al Mirahma Febri Kurnianti, Rizarullah, Aditya Hanung Setyadi, Anita Artarini, Marselina Irasonia Tan, Catur Riani, Dessy Natalia, Reza Aditama, Husna Nugrahapraja

“…Methods: To design a multivariant vaccine, 20,567 sequences consisting of all SARS-CoV-2′s variants of concern whole genome were retrieved. …”
Get full text

Travel-related potential rabid animal post-exposure consultation at the Thai Travel Clinic, Hospital for Tropical Diseases, Bangkok, Thailand by Rachata Charoenwisedsil, Tanatorn Soravipukuntorn, Katawut Panyatanakun, Phimphan Pisutsan, Panita Looareesuwan, Punyisa Asawapaithulsert, Hisham Ahmed Imad, Sophie Schneitler, Watcharapong Piyaphanee, Wasin Matsee

“…This retrospective review aims to analyze post-exposure rabies consultations at the Thai Travel Clinic providing insights into epidemiology, risk factors, and post-exposure management for international travelers. Methods: A retrospective study included international travelers of all ages who visited the Thai Travel Clinic at the Hospital for Tropical Diseases in Bangkok, Thailand for potential rabid animal post-exposure management between January 1, 2019, and March 31, 2024. …”
Get full text

The MFGE8/integrin β3 axis mitigates experimental neutrophilic asthma by suppressing NLRP3-Caspase-1 pathway-mediated NETosis by Shanshan Wang, Tang Kun, Zhen Tian, Mengqi Huang, Yan Fan, Boyu Li, Hongyan Zheng, Rongman Xu, Meijia Wang, Jianping Zhao, Jungang Xie

“…However, the role of this glycoprotein in neutrophilic asthma has not been thoroughly investigated. Methods MFGE8 concentrations were assessed in asthmatic patients with various endotypes. …”
Get full text

Early-life tobacco smoke elevating later-life osteoporosis risk: Mediated by telomere length and interplayed with genetic predisposition by Dongsheng Di, Haolong Zhou, Zhangbo Cui, Jianli Zhang, Qian Liu, Tingting Yuan, Tingting Zhou, Xiao Luo, Danyang Ling, Qi Wang

“…The mediating role of telomere length (TL) and the interaction with genetic predisposition were also studied. Methods: Data on in utero tobacco smoke exposure (IUTSE) status and age of tobacco use initiation from the UK Biobank were used to estimate early-life tobacco smoke exposure. …”
Get full text

Healthcare-Seeking behavior for acute respiratory infections in a community population in Southwest China during the 2021–2023 influenza seasons by Qing Wang, Mingyue Jiang, Tingting Li, Yuhua Ren, Jiang Long, Jia Li, Yunshao Xu, Yanlin Cao, Jie Qian, Weizhong Yang, Mengmeng Jia, Li Qi, Luzhao Feng

“…Methods A cross-sectional community questionnaire survey was carried out in Wanzhou, a district in southwest China, following the winter-spring influenza peaks in the 2021-2022 and 2022-2023 seasons. …”
Get full text

Is neutropenia still the main risk factor for invasive aspergillosis? A contemporary university hospital retrospective cohort of invasive aspergillosis in neutropenic and non-neutr... by Andrea Gutiérrez-Villanueva, Itziar Diego-Yagüe, Isabel Gutiérrez-Martín, Sonia García-Prieto, Edith Gutiérrez-Abreu, Román Fernández-Guitián, Isabel Castilla-Martínez, Naomi Bermejo-Moreno, Nuria Miguel-Ontañon, Jorge Calderón-Parra, Alejandro Callejas-Díaz, Alberto Díaz-de Santiago, Sara de la Fuente-Moral, Elena Múñez-Rubio, Sarela García-Masedo, Isabel Sánchez-Romero, Antonio Ramos-Martínez, Ana Fernández-Cruz

“…Methods Retrospective observational study including all adult patients admitted to the Puerta de Hierro-Majadahonda Hospital between January 2018 and April 2024 with IA. …”
Get full text

Different Gene Preferences of Maple Syrup Urine Disease in the Aboriginal Tribes of Taiwan by Jia-Woei Hou, Tsann-Long Hwang

“…Materials and methods: To identify and detect the carrier frequency of MSUD in Taiwanese Aboriginal tribes, we performed biochemical and molecular studies from peripheral blood in MSUD patients and dried blood on filter paper in the enrolled screened populations. …”
Get full text

Prevention of rabies in Southern Siberia by I. D. Zarva, A. D. Botvinkin

“…To substantiate the need for coordinating measures to prevent rabies in adjacent territories with similar conditions for the spread of this infection.Materials and Methods. We retrospectively analyzed spatiotemporal trends in rabies spread during 1950-2020 by studying available statistics from nine Siberian territories (Altai Republic, Altai Region, Tyva Republic, Khakassia, Buryatia, Krasnoyarsk Region, Transbaikal Region, Irkutsk Region and Kemerovo Region). …”
Get full text

Placental Inflammatory Changes and Bacterial Infection in Premature Neonates with Respiratory Failure by S. A. Perepelitsa, A. M Golubev, V. V Moroz, S. V. Alekseyeva, V. A. Melnichenko

“…Objective: to reveal a relationship of placental inflammatory changes to bacterial infection in premature neonates with respiratory failure. Material and methods. Bronchoalveolar aspirate was bacteriologically studied in 157 premature neonates with respiratory distress syndrome (NRDS); the total and differential leukocyte counts were measured in their peripheral blood. …”
Get full text

Beyond Anesthesia: Ketamine’s Expanding Role in Chronic Pain and Psychiatric Disorders by Christopher Zaki

“…We assess its analgesic properties, FDA-approved application in the form of Spravato (esketamine) for depression, and off-label use for analgesia and psychiatric disorders. Methods: A systematic search of PubMed, Cochrane Library, and Scopus databases identified studies on ketamine’s efficacy and safety in chronic pain and psychiatric disorders. …”
Get full text

Detectability of Chiari Malformation and Other Craniovertebral Junction Anomalies Using Computed Tomography by M. N. Mikhailova, O Yu. Kostrova, P. A. Svyatochevskiy, L. M. Merkulova, G. Yu. Struchko, Yu. I. Pavlov, A. Yu. Semenov

“…The most clinically significant is the Chiari malformation (CM), or Arnold–Chiari anomaly.Objective: to analyze the incidence of various types of CM, Kimmerle anomaly (KA) and other craniovertebral anomalies, assess its dependence on craniometric parameters according to the protocols of radiological studies and neurosurgical department data for 5 years.Material and methods. …”
Get full text

Bone mineral density and vertebral fractures in patients with systemic lupus erythematosus: A systematic review and meta-regression. by Claudia Mendoza-Pinto, Adriana Rojas-Villarraga, Nicolás Molano-González, Erick A Jiménez-Herrera, María de la Luz León-Vázquez, Álvaro Montiel-Jarquín, Mario García-Carrasco, Ricard Cervera

“…BMD mean difference in cases/controls: -0.0566 95% CI (-0.071, -0.0439; p = < 0.0001). …”
Get full text

Using Seroprevalence and Immunisation Coverage Data to Estimate the Global Burden of Congenital Rubella Syndrome, 1996-2010: A Systematic Review. by Emilia Vynnycky, Elisabeth J Adams, Felicity T Cutts, Susan E Reef, Ann Marie Navar, Emily Simons, Lay-Myint Yoshida, David W J Brown, Charlotte Jackson, Peter M Strebel, Alya J Dabbagh

“…Previous estimates considered the year 1996 and only 78 (developing) countries.<h4>Methods</h4>We reviewed the literature to identify rubella seroprevalence studies conducted before countries introduced rubella-containing vaccination (RCV). …”
Get full text

Challenging Behaviors in Children with Nonverbal Autism: A Questionnaire to Guide the Design of a Wearable Device for Biomarker Recording by Anne-Sophie Weber, Camilla Barbini, Olivia Vidal, Laura M. Ferrari, Dimitri Thellier, Alexandre Derreumaux, Esma Ismailova, Florence Askenazy, Susanne Thümmler

“…Nonetheless, this population remains rarely studied in clinical research. Recent methods use electrophysiological biomarkers as diagnostic tools to detect stress signals, which may be useful in anticipating situations or conditions leading to challenging behaviors in nmvASD. …”
Get full text

Impact of COVID-19 pandemic on rates of congenital heart disease procedures among children: prospective cohort analyses of 26 270 procedures in 17 860 children using CVD-COVID-UK c... by Andrew Thompson, Rui Providência, Matthew Sperrin, Swapna Mandal, Ashley Akbari, Pia Hardelid, Ruth Gilbert, Christopher Tomlinson, John Macleod, Francesco Zaccardi, Kamlesh Khunti, Naveed Sattar, Antony Palmer, Munir Pirmohamed, Rocco Friebel, Mira Hidajat, Colin Berry, Richard Williams, Johnny Downs, Neil Pearce, Anthony Khawaja, Cathie Sudlow, Adnan Tufail, Samira Bell, Huan Wang, Vahe Nafilyan, Ann John, Lois Kim, Anvesha Singh, Kazem Rahimi, Gianni D Angelini, Frank Kee, Tim Wilkinson, Shirley Sze, Nick Hall, Hector Chinoy, Elizabeth A Ellins, Gianni Angelini, Massimo Caputo, Serban Stoica, Alan Carson, Dorothea Nitsch, Sarah Steeg, David Osborn, Joseph Firth, Christina Pagel, Sonya V Babu-Narayan, Ana-Catarina Pinho-Gomes, Holly Pavey, Harry Hemingway, Mark Thomas, Mamas Mamas, Julia Hippisley-Cox, Kim Kavanagh, Ronan Lyons, Ernest Wong, Philip Stone, Hayley Evans, Donna Wakefield, Katherine Sleeman, Julian Halcox, Dexter Canoy, Mohamed Mohamed, Amar Shah, Ioanna Tzoulaki, Gareth Davies, Athina Spiliopoulou, Anna Hansell, Suzanne Mason, John Danesh, Elijah Behr, Eva Morris, Riyaz Patel, Glen Martin, Evan Kontopantelis, Pedro Machado, Katherine Brown, Tasanee Braithwaite, Maya Buch, Paz Tayal, Ify Mordi, Jianhua Wu, Simon Williams, Bernard Keavney, Ajay Shah, Krishnaraj Rathod, Alastair Proudfoot, Fu Siong Ng, Manuel Gomes, Arunashis Sau, Jonathan Sterne, Michelle Williams, John Cleland, Theresa McDonagh, Jocelyn Friday, Ramesh Nadarajah, Steffen Petersen, Rupert Payne, Angela Wood, Mark Green, David Jenkins, Akshay Shah, Jayati Das-Munshi, Alexandru Dregan, Debbie A Lawlor, Angela Henderson, Elsie Horne, Mehrdad Mizani, David Hughes, Robert Aldridge, Katharine Looker, Reecha Sofat, Norman Briffa, Sonya Crowe, Katie Harron, Amanda Marchant, Elena Nikiphorou, Vasa Curcin, Deborah Kinnear, Craig Melville, Neil Davies, Marion Bennie, Joseph Kamtchum Tatuene, David Cromwell, Daniel Bromage, Michael Allen, Kerry Pearn, Terry Quinn, John Dennis, Lorna Fraser, Sandosh Padmanabhan, Sinéad Langan, Stephen McKeever, Irene Higginson, Anna Bone, Tom Palmer, Camille Carroll, Christian Schnier, Linxin Li, Rachel Denholm, Sarah Cook, Julia Townson, Dan Jones, John Nolan, Frederick Ho, Felix Greaves, Sara Khalid, Gayan Perera, Baljean Dhillon, Antonio Cannatà, Antonio Gasparrini, Laia Bécares, Clare Gillies, Samuel Kim, Abraham Olvera-Barrios, Roy Schwartz, Jennifer Quint, Wen Shi, Nazrul Islam, Craig Smith, Spiros Denaxas, Cathie L M Sudlow, Lynn Morrice, Qi Huang, Sharmin Shabnam, Parag Gajendragadkar, Gareth Williams, Fiona Pearce, Hannah Whittaker, John Ford, Iain Marshall, Benedict Michael, Alastair Denniston, Florian Falter, Rouven Priedon, William Whiteley, Geneviève Cezard, Jane Lyons, Fatemeh Torabi, Laura North, Helen Colhoun, Majel McGranahan, Stephen Kaptoge, Martin Rutter, Laura Pasea, Eoin McKinney, Alexei Yavlinsky, Alasdair Warwick, Max Lyon, Rebecca Reynolds, Amanj Kurdi, Seb Bacon, Jessica Barrett, Joseph Newman, Muhammad Rashid, Annemarie Docherty, Joanna Davies, Deepti Gurdasani, Natasha Chilman, Sarah Onida, Carole Morris, Samantha Ip, Venexia Walker, Alvina Lai, Alex Handy, Alun Davies, Arun Pherwani, Ashkan Dashtban, Caroline Dale, Caroline Rogers, Claire Lawson, Dan O’Connell, Daniel Harris, David Brind, Deborah Lawler, Deborah Lowe, Eloise Withnell, Ewan Birney, Fabian Falck, George Nicholson, Gwenetta Curry, Haoting Zhang, Harry Wilde, Hoda Abbasizanjani, Honghan Wu, Jennifer Beveridge, Johan Thygesen, Kate Cheema, Ken Li, Livia Pierotti, Lucy Wright, Mark Barber, Mary Joan Macleod, Michalis Katsoulis, Mike Inouye, Moritz Gerstung, Myer Glickman, Paula Lorgelly, Qiuju Li, Raph Goldacre, Rohan Takhar, Ruwanthi Kolamunnage-Dona, Safa Salim, Seamus Kent, Sonya Babu-Narayan, Spencer Keene, Thomas Lawrence, Tianxiao Wang, Eleanor Walsh, Antonella Delmestri, Jill Pell, David Powell, Tomas Fitzgerald, Kelly Fleetwood, Ross Forsyth, Richard Fitzgerald, Yi Mu, Amy Ronaldson, Kerrie Stevenson, Shane Johnson, Richard Chin, Luisa Zuccolo, Elias Allara, Caroline Jackson, Yvonne Nartey, Kate Brown, Hannah Harrison, Peter Bath, Tom Yates, Iain Squire, Jon Shelton, Carin Van Doorn, Maria Sudell, Matthew Bown, Tom Pape, Tim Chico, Robert Fletcher, Mevhibe Hocaoglu, Owen Pickrell, Steven Zhao, Laura Sherlock, Andrew Constantine, Andrew Mason, Cameron Razieh, Steven Kerr, James Sheppard, David Selby, Emeka Chukwusa, Rachel Cripps, Paul Madley-Dowd, Patrick Bidulka, Zeljko Kraljevic, Nuria Sanchez, Martha Elwenspoek, Tanja Mueller, Yohhei Hamada, Daniel King, Han-I Wang, Tim Dong, Shubhra Sinha, Jeremy Chan, George Tilston, Verónica Cabreira, Simon Ellershaw, Simon Frain, Ruth Norris, Huw Strafford, Marie-Louise Zeissler, Nushrat Khan, Daniel Morales, Yoryos Lyratzopoulos, Jennifer Rossdale, Filip Sosenko, Sarah Wang, Johannes Heyl, Julia Ive, Petter Brodin, Matthew O’Connell, Becky White, Dominic Oliver, Stephanie Lax, Shishir Rao, Mohammad Mamouei, Ninian Lang, Libor Pastika, Benjamin Zuckerman, Samaira Khan, Xiaomin Zhong, Thomas Porter, Kurt Taylor, Charlotte Parbery-Clark, Simone Croft, Jadene Lewis, Yogini Chudasama, Lars Murdock, Pardis Biglarbeigi, Melissa Webb, Nida Ahmed, Tapiwa Tungamirai, Baboucarr Njie, Renin Toms, Rochelle Knight, Marwa AL Arab, Alexia Sampri, Ruth Watkinson, Laila Tata, Lisa Pennells, Catriona Harrison, Thomas Bolton, Ana Torralbo, Fionna Chalmers, Anna Stevenson, Andrew Lambarth, Naomi Launders, Emanuele Di Angelantonio, Ferran Espuny-Pujol, Arun Karthikeyan Suseeladevi, Rony Arafin, Zainab Karim, Martina Slapkova, Rosie Hinchliffe, Lily Benton, Alexis Webb, Annette Jackson, James Farre, Jemma Austin, Zach Welshman, Costas Kallis, Juliette Unwin, Alistair Marsland, Sara Holloway, Adejoke Oluyase Abdel Douiri, Charles Wolfe Ben Bray, Harry Watson, Javiera Leniz Martelli, Linglong Qian, Richard Killick, Arturo de la Cruz, Julian Matthewman, Thiago Silva, Zhengnan Zhu, Alex Grundmann, Adam Hollings, Angeliki Antonarou, Daniel Schofield, Elizabeth Kelly, Humaira Hussein Richardson, Jake Kasan, Nickie Wareing, Russell Healey, Shoaib Ali Ajaib, Vandana Ayyar-Gupta, Xinkai Wang, Marcos del Pozo Banos, Ami Banerjee, Andrej Ivanovic, Ashley Dickson, Chu Siyu, Emma Whitfield, Eva Keller, Evaleen Malgapo, lavien Hardy, Floriaan Schmidt, Freya Allery, Jinge Wu, Louise Choo, Luca Grieco, Matt Sydes, Tuankasfee Hama, Waty Lilaonitkul, Arun Karthikeyan Suseeladevi, Dann Mitchell Ben Gibbison, Ewan Walker, Yueying Li, Carmen Petitjean, Chimweta Chilala, Chriselda Oliver, Elena Raffetti, Eric Harshfield, Isabel Walter, Katie Saunders, Mayank Dalakoti, Megan Ritson, Millie Zhou, Rutendo Mapeta, Stelios Boulitsakis Logothetis, Xilin Jiang, Xiyun Jiang, Yanfan Li, Alice Hosking, Carlos Sanchez Soriano, Claire Tochel, Joe Mellor, Luke Blackbourn, Miguel Bernabeu Llinares, Niamh McLennan, William Berthon, Clea du Toit, Dennis Tran, Salil Deo, Francesca Zaccagnino, Eva Henning, Lana Bojanic, Zenas Yiu, Precious Onyeachu, Ralph Akyea, Aashna Uppal, Ben Lacey Ben Goldacre, Dani Prieto-Alhambra, Marta Pineda Moncusi, Paula Dhiman,ingze Gu, Salma Chaudhry, Seyed Alireza Hasheminasab, Zeinab Bidel Taleshmekaeil, Leuven Nathalie Conrad, Jen-Yu Amy Chang, Christina van der Feltz-Cornelis

“…Our aim was to assess the impact on paediatric congenital heart disease (CHD) procedures during different pandemic periods compared with the prepandemic period, to inform appropriate responses to future major health services disruptions.Methods and results We analysed 26 270 procedures from 17 860 children between 1 January 2018 and 31 March 2022 in England, linking them to primary/secondary care data. …”
Get full text