Blurring the lines: an empirical examination of the interrelationships among acceptability, appropriateness, and feasibility by Zoe Fehlberg, Zornitza Stark, Marlena Klaic, Stephanie Best

“…To categorize interrelationships and generate feedback loops, survey data were analyzed using descriptive and correlation statistics and interpreted alongside interview data analyzed using content analysis. …”
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Methylglyoxal-induced RNA modifications decrease RNA stability and translation and are associated with type 2 diabetes by Edwin De Jesus Lopez Gonzalez, SWT Lai, Kelani Sun, Caree R. Carson, Carlos Hernandez-Castillo, Tala Zoukari, Kassandra Lopez, Jianying Zhang, Thomas Blevins, John Termini, Sarah C. Shuck

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Artificial intelligence and health empowerment in rural communities and landslide- or avalanche-isolated contexts: real case at a fictitious location by Rune Johan Krumsvik, Vegard Slettvoll

“…Therefore, all LLM recommendations and technology support were reviewed during an in-person physician examination in a family network, and the final antibiotic prescription came from the clinician, underscoring that AI functioned solely as decision support rather than autonomous care.…”
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Childcare Strategies of Single Mothers in the Face of Marketised Health Services by Frida Emilia Horta-Garduño, Ybette Karen Ramos-Gutiérrez, Itzia María Cazares Palacios

“…Mothers find it necessary to generate functional strategies to care for their children’s health, leaving aside their own physical and mental care, as it is more important for them to keep their children safe and healthy.…”
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Ultrasound-activated bimetallic PtRu alloy nanozymes for synergistic sonodynamic and chemodynamic therapy of multidrug-resistant bacterial infection by Xiang Zheng, Lingxia Pang, Youpei Wang, Qianlei Zhao, Guoquan Pan, Xiaojun He, Yafeng Liang

“…By carefully optimizing the atomic ratio of platinum (Pt, catalytic sites) to ruthenium (Ru, adsorption sites), we synthesized ultrafine bimetallic alloy nanoplatforms with enhanced functional performance. …”
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Pixel-super-resolved lens-free quantitative phase microscopy with partially coherent illumination by Yang Chen, Xuejuan Wu, Linpeng Lu, Jiasong Sun, Runnan Zhang, Wenhui Lin, Yufan Chen, Maciej Trusiak, Peng Gao, Chao Zuo

“…Abstract Lens-free on-chip microscopy (LFOCM) has been widely utilized in digital pathology, drug screening, point-of-care testing (POCT), and quantitative phase imaging (QPI) due to its high throughput imaging capability and compactness. …”
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A systematic review and meta-analysis of urinary incontinence following successful obstetric fistula repair: findings from five countries in sub-Saharan Africa by Gedion Asnake Azeze, Kirubel Eshetu Haile, Natnael Atnafu Gebeyehu, Sintayehu Solomon Kena, Tewodros Getachew Tsegaye, Amanuel Yosef Gebrekidan, Yitateku Alelgn, Gizachew Ambaw Kassie, Yordanos Sisay Asgedom

“…Urinary incontinence following the repair of obstetric fistula remains a significant health problem and can greatly damage a women’s ability to function confidently. There are approximately two million women suffering from urinary incontinence following obstetric fistula repair, most of whom are primarily in Africa. …”
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Effect of oral sodium bicarbonate supplementation on urine TGF-𝜷 in normal serum bicarbonate CKD, a randomized controlled trial by Nipon Ngupis, Bancha Satirapoj, Theerasak Tangwonglert, Ouppatham Supasyndh, Paramat Thimachai, Narongrit Siriwattanasit

“…Abstract The consequences of chronic subclinical metabolic acidosis, characterized by an increase in single nephron ammonium generation, contribute to the progression of chronic kidney disease (CKD). …”
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Lost microbes of COVID-19: Bifidobacterium, Faecalibacterium depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severity by Eamonn MM Quigley, Thomas J Borody, Sabine Hazan, Neil Stollman, Huseyin S Bozkurt, Sonya Dave, Andreas J Papoutsis, Jordan Daniels, Brad D Barrows

“…Objective The study objective was to compare gut microbiome diversity and composition in SARS-CoV-2 PCR-positive patients whose symptoms ranged from asymptomatic to severe versus PCR-negative exposed controls.Design Using a cross-sectional design, we performed shotgun next-generation sequencing on stool samples to evaluate gut microbiome composition and diversity in both patients with SARS-CoV-2 PCR-confirmed infections, which had presented to Ventura Clinical Trials for care from March 2020 through October 2021 and SARS-CoV-2 PCR-negative exposed controls. …”
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The model of saving the mental health of the adolescent population in the city of Kirov by M V Zlokazova, N V Semakina

“…A special position in the healthcare of the Russian Federation is occupied by the protection of the health of the younger generation, therefore, in the implementation of national projects, much attention is paid to the development of infrastructure for providing multiprofessional medical care to children and the prevention of mental and somatic diseases.Purpose. …”
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Strategies and applications of antibacterial surface-modified biomaterials by Qianwei Su, Yunyun Xue, Chuyao Wang, Qirong Zhou, Yu Zhao, Jiacan Su, Baoku Zhu

“…The review also highlights current and emerging applications in medical implants, wound care, and hygienic textiles. Finally, key limitations and future opportunities are critically examined, offering insights into the rational design and clinical translation of next-generation antibacterial biomaterials.…”
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Trends and advances in Leptospira, a bibliometric analysis by Wei Wang, Wei Wang, Wei Wang, Yamin Gao, Yamin Gao, Yamin Gao, Jianyu Ji, Jianyu Ji, Jianyu Ji, Zhai Huang, Zhai Huang, Bin Xiong, Bin Xiong, Shulin Xiang, Shulin Xiang

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Integrated transportation system planning with gravitational search algorithm approach based on fuzzy mutant controller by Alireza Hosseinzadeh Kashani, Seyed Ahmad Shayannia, Mohammad Mehdi Movahedi, Soheila Sardar

“…The search algorithm was used in solving 23 standard benchmark functions, including single mode and multi-mode functions.…”
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Isoliensinine exerts antitumor effects in lung adenocarcinoma by inhibiting APEX1-driven ROS production by Cheng Chen, Cheng Chen, Cheng Chen, Chenying Shu, Dan Shen, Dan Shen, Dan Shen, Zhaowei Yan, Zeyi Liu, Zeyi Liu, Zeyi Liu, Jian-An Huang, Jian-An Huang, Jian-An Huang

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Dynamic survival prediction of end-stage kidney disease using random survival forests for competing risk analysis by Daniel Christiadi, Daniel Christiadi, Daniel Christiadi, Kevin Chai, Aaron Chuah, Bronwyn Loong, Thomas D. Andrews, Aron Chakera, Giles Desmond Walters, Giles Desmond Walters, Giles Desmond Walters, Simon Hee-Tang Jiang, Simon Hee-Tang Jiang, Simon Hee-Tang Jiang

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Super‐Enhancer‐Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T‐ALL Cell Growth and Survival by Juanjuan Yu, Zimu Zhang, Yanling Chen, Jianwei Wang, Gen Li, Yanfang Tao, Yongping Zhang, Yang Yang, Chenyue Zhang, Tiandan Li, Jia Cheng, Tongtign Ji, Zhongling Wei, Wenjuan Wang, Fang Fang, Wei Jiang, Peipei Chu, Hongli Yin, Di Wu, Xiaolu Li, Xiaodong Wang, Jun‐Jie Fan, Shaoyan Hu, Zhen‐Hong Zhu, Shuiyan Wu, Jun Lu, Jian Pan

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Dual targeting of the mitochondrial Lon peptidase 1 and the chymotrypsin-like proteasome activity as a potential therapeutic strategy in malignant astrocytoma models by Christopher Douglas, Shashi Jain, Naomi Lomeli, Javier Lepe, Kaijun Di, Nitesh Kumar Nandwana, Adil Shareef Mohammed, Thao Vu, James Pham, Maria Cristina Kenney, Bhaskar Das, Daniela A. Bota

“…Using gain- and loss-of-function genetic models, we discovered that LonP1 is both necessary and sufficient to drive BT317 drug sensitivity in established and patient-derived glioma stem-like cells by generating ROS and inducing apoptosis. …”
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Investigating the Prospects of ChatGPT in Training Medicinal Chemists and the Development of Novel Drugs by Michell O. Almeida, Artur C. G. Soares, Gustavo H. M. Sousa, Witor R. Ferraz, Gustavo Trossini

“…Furthermore, it can assist in the database cleaning process and create customized functions for performing specialized tasks. However, ChatGPT does possess some limitations, such as frequent occurrences of artificial hallucinations (a response generated by AI that comprises erroneous or misleading information presented as true), the inability to process multimodal information, and the potential for biases in its training datasets. …”
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Approaches to assess new pneumococcal vaccines for immunogenicity, development and licensure by Feroze A. Ganaie, Moon H. Nahm

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Influenza preparedness in low-resource settings: a look at oxygen delivery in 12 African countries by Janeil M Belle, Hillary J Cohen, Nahoko Shindo, Matthew L Lim, Adriana Velazquez-Berumen, Jean-Bosco Ndihokubwayo, Meena N Cherian

“…Data was stored in the WHO DataCol SQL database and computerized spreadsheet tools were used to generate descriptive statistics.  Results: Ninety-nine (43.8%) of facilities surveyed reported uninterrupted access to an oxygen source and 55 (24.6%) possessed a fully functioning oxygen concentrator.  …”
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