Themis differentially regulates T follicular helper cell differentiation during early and late stages of chronic viral infection by Yuzhen Zhu, Yuzhou Bao, Ning Wang, Qifeng Gan, Jian Tang, Yu Cong, Bowen Hou, Bowen Hou, Minxue Quan, Chaonan Yan, Siyi Liu, Shuo Lin, Xiaobin Zhang, Yanping Du, Lichao Hou, Nicholas R. J. Gascoigne, Nicholas R. J. Gascoigne, Bing Xu, Guo Fu, Guo Fu, Guo Fu, Qifan Zheng

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Multiple, not single, recipient muscle tendon transfers produce well-coordinated thumb-tip movement in lateral pinch grasp: a simulation study with application to restoration of im... by Cole D. Smith, Joseph D. Towles

“…We calculated CMC joint ab/adduction deviation from the flexion–extension plane and IP joint flexion in the plane that all muscle groups produced and compared those joint angle movements to those of the FPL when it alone drove the thumb.ResultsOf the 27 simulations, three muscle groups, each consisting of three or four muscles, generated lower IP joint flexion and CMC joint ab/adduction compared with the FPL.ConclusionThis study points to the potential of novel, multiple recipient muscle tendon transfer surgeries to outperform the current standard of care to restore lateral pinch grasp following tetraplegia.…”
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Validation of a Clinical Scale for Early Detection of Infections at the Exit Site of Central Venous Catheters for Hemodialysis by José Luis Cobo-Sánchez, Ian Blanco-Mavillard, Raquel Pelayo-Alonso, Noelia Mancebo-Salas, Ismael Fernández-Fernández, Irene Larrañeta-Inda, Ana Ulzurrun-García, Isidro Sánchez-Villar, Fernando González-García, Julia Hernando-García, Ma Jesús Rollán-de la Sota, Luís Miguel Vieira-Barbosa Lopes, Ma del Rosario Prieto-Rebollo, Carolina Sesmero-Ramos, Catalina Jaume-Riutort, Rafael Casas-Cuesta, Mateo Alcántara-Crespo, Joan Ernest de Pedro-Gómez

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Association of the blood urea nitrogen to serum albumin ratio and all-cause mortality in critical ill acute ischemic stroke patients: a retrospective cohort study of MIMIC-IV datab... by Yongwei Huang, Zongping Li, Jianjun Wang, Jianjun Wang, Decai Wang, Decai Wang, Xiaoshuang Yin

“…PurposeWe aim to ascertain the extent to which the blood urea nitrogen (BUN) to serum albumin (ALB) ratio (BAR) could be implemented to anticipate the short- and long-term prognosis of acute ischemic stroke (AIS) patients in intensive care units (ICUs).MethodsThe data was derived from the Marketplace for Intensive Care Medical Information-IV (MIMIC-IV v3.0) database, primarily pertaining to AIS patients as categorized by the International Classification of Diseases (ICD)-9 and ICD-10. …”
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Quantitative Relationships Between Basalt Geochemistry, Shear Wave Velocity, and Asthenospheric Temperature Beneath Western North America by M. Klöcking, N. J. White, J. Maclennan, D. McKenzie, J. G. Fitton

“…Forward and inverse modeling of carefully selected major, trace, and rare earth elements were used to determine melt fraction as a function of depth. …”
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Autonomous and sustainable machine learning: pursuing new horizons of intelligent systems by Witold Pedrycz

“…The carefully crafted learning process has to result with advanced models. …”
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Action Observation for Children and Adolescents with Cerebral Palsy: Hope or Hype? A Systematic Review with Meta-Analysis by José Fierro-Marrero, Carlos Donato Cabrera-López, Borja Rodríguez de Rivera-Romero, Alejandro López-Mejías, Mirari Ochandorena-Acha, Sergio Lerma-Lara, Roy La Touche

“…Cerebral palsy generates an elevated burden on both patients and health-care systems. …”
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Designing A Blockchain-Empowered Telehealth Artifact for Decentralized Identity Management and Trustworthy Communication: Interdisciplinary Approach by Xueping Liang, Nabid Alam, Tahmina Sultana, Eranga Bandara, Sachin Shetty

“… BackgroundTelehealth played a critical role during the COVID-19 pandemic and continues to function as an essential component of health care. …”
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Lifestyle factors and health outcomes associated with infertility in women: A case-control study using National Health Insurance Database by Boyoung Jeon, Taeuk Kang, Sung Wook Choi

“…Conclusions These findings underscore the need for lifestyle modifications and personalized preconception care to improve fertility outcomes. Trial registration Not available.…”
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Deletion of Tfap2a in hepatocytes and macrophages promotes the progression of hepatocellular carcinoma by regulating SREBP1/FASN/ACC pathway and anti-inflammatory effect of IL10 by Zhiwei Li, Chun Zhang, Guixiang Huang, Zixin Zhang, Qinghao Wang, Xiran Liu, Yanling Qin, Hao Zhou, Anyi Hou, Jun He, Limin Li, Xiang Hu, Xiaofeng Ding

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Stereotactic body radiotherapy: a new non-invasive way to conduct pulmonary artery denervation by Manzhen Liao, Manzhen Liao, Taoyue Yao, Yonghui Xie, Shelby Kutty, Jinqiao Liu, Wei Peng, Wei Peng, Ting Huang, Huaiyang Chen, Huaiyang Chen, Haoqin Fan, Zhenghui Xiao, Qiming Liu, Yunbin Xiao

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Multi-omics integration reveals Vha68-3 as a testicular aging-specific factor that coordinates spermatid elongation through mitochondrial metabolic homeostasis by Jun Yu, Qiuru Huang, Yangbo Fu, Lei He, Cong Shen, Xia Chen, Zhiran Li, Jiaxin Li, Chenyu Wang, Xinda Wang, Binbin Yang, Ziwen Lin, Chen Qiao, Xiaofang Tan, Xiaoqing Yang, Hao Chen, Ying Zheng, Bo Zheng, Fei Sun

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Study protocol using informatics to identify and recruit a cohort of older adults in Florida to develop teleneuropsychological norms by Glenn Smith, Ambar Perez-Lao, Gelan Ying, Ellie Mitova, Amanda Morales, David Marra, Franchesca Arias, Shellie-Anne Levy

“…They will also complete questionnaires related to sociodemographic information, depression, functionality and social determinants of health. Participants will undergo a teleneuropsychological battery examination via remote assessment. …”
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Humanized scFv Molecule Specific to an Extracellular Epitope of P2X4R as Therapy for Chronic Pain Management by Adinarayana Kunamneni, Karin N. Westlund

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Evaluation Of The Role Of Visual Evoked Potentials In Detecting Visual Impairment In Type II Diabetes Mellitus by Ruchi Kothari, Pradeep Bokariya, Smita Singh, TS Hemavaishnave

“…Both eyes of the two groups of the subjects were included in the study. Design:- Tertiary care rural hospital based, single time assessment, short term observational study. …”
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Combined metabolomic and transcriptomic analysis reveals the key genes for triterpenoid biosynthesis in Cyclocarya paliurus by Duo Chen, Xupeng Chen, Xuehai Zheng, Jinmao Zhu, Ting Xue

“…Abstract Background Cyclocarya paliurus is a high-value tree, and it contains a variety of bioactive secondary metabolites which have broad application prospects in medicine, food and health care. Triterpenoids can improve the bioactive function of C. paliurus health tea and also improve the efficacy of health care tea. …”
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A Digital Mental Health Solution to Improve Social, Emotional, and Learning Skills for Youth: Protocol for an Efficacy and Usability Study by Kayla V Taylor, Laurent Garchitorena, Carolina Scaramutti-Gladfelter, Mykayla Wyrick, Katherine B Grill, Azizi A Seixas

“…ConclusionsThe STEMSEL study plays a crucial role in assessing the feasibility and adoption of digital mental health interventions within the school-aged youth population in the United States. The findings generated from this study have the potential to dismantle obstacles to accessing mental health assistance and broaden the availability of care through evidence-based strategies. …”
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“It’s like going through life at a mediocre level”: a qualitative study of the meaning and impact of fatigue in children and young people with sickle cell disease by Brenda Agyeiwaa Poku, Karl Michael Atkin, John David Grainger, Iyamide Thomas, Rachael Oshinbolu, Abubakar Mohammed, Edith Kyewalyanga, Susan Kirk

“…Conclusions Fatigue dominates CYP’s experience of living with SCD, significantly impacting their physical, social and educational functioning and leading to isolation and stigma. Often overlooked in clinical settings, addressing fatigue should be integral to SCD care and research. …”
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Fermented Dairy Products as Precision Modulators of Gut Microbiota and Host Health: Mechanistic Insights, Clinical Evidence, and Future Directions by Yuan Gao, Yanyan Liu, Tingting Ma, Qimeng Liang, Junqi Sun, Xiaomeng Wu, Yinglong Song, Hui Nie, Jun Huang, Guangqing Mu

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Idiopathic Pulmonary Fibrosis Registry China study (PORTRAY): protocol for a prospective, multicentre registry study by Ling Zhao, Min Liu, Huaping Dai, Chen Wang, Bingbing Xie, Yanhong Ren, Jing Geng, Xuan He, Chengjun Ban, Shiyao Wang, Dingyuan Jiang, Sa Luo, Qihang Chen, Ruie Feng

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