Activity outcomes after hip arthroplasty: an information tool based on patients’ experience captured in a hospital registry by S. Cole, G. Fabiano, C. Barea, S. Cullati, T. Agoritsas, N. Gutacker, A.J. Silman, D. Hannouche, A. Lübbeke, Rafael Pinedo-Villanueva

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The global and national burden of chronic kidney disease attributable to ambient fine particulate matter air pollution: a modelling study by Yan Yan, Benjamin Bowe, Yan Xie, Ziyad Al-Aly, Elena Artimovich, Miao Cai

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Pressure Properties of a New Positive Expiratory Pressure Device—OpenUp Flow a Three‐in‐One Solution by Pär Wennberg, Bengt Sundberg, Elisabeth Westerdahl

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Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects by Qiuli Xu, Xin Hua, Bingbing Li, Bei Jiang, Jiajia Jin, Ranpu Wu, Yanli Gu, Hao Xu, Qinpei Cheng, Suhua Zhu, Fang Zhang, Tangfeng Lv, Yong Song

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Lactylation-driven TNFR2 expression in regulatory T cells promotes the progression of malignant pleural effusion by Yao Liu, Qiong Zhou, Siyu Zhang, Wenbei Peng, Haolei Wang, Xuan Xiang, Linlin Ye, Xiaoshan Wei, Zihao Wang, Qianqian Xue

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Important features of retail shoes for women with rheumatoid arthritis: A Delphi consensus survey. by Peta Ellen Tehan, William J Taylor, Matthew Carroll, Nicola Dalbeth, Keith Rome

“…<h4>Objectives</h4>Footwear management aims to preserve foot function, reduce the burden of foot pain and maintain joint mobility in women with rheumatoid arthritis (RA). …”
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Impact of Coconut Oil and Its Bioactive Metabolites in Alzheimer’s Disease and Dementia: A Systematic Review and Meta-Analysis by Duaa Bafail, Abrar Bafail, Norah Alshehri, Noura Hamdi Alhalees, Ahmad Bajarwan

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LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of PD-L1 protein in non-small cell lung cancer by Wei Liu, Dong Wang, Qing Miao, Peilin Chen, Hongbing Liu, Jiawen Lv, Jie Yin, Jian Feng, Yong Song, Tangfeng Lv, Mingxiang Ye, Wenjie Yan, Liting Lv, Sutong Zhan

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Late‐Stage Skeletal Muscle Transcriptome in Duchenne Muscular Dystrophy Shows a BMP4‐Induced Molecular Signature by Hanna Sothers, Xianzhen Hu, David K. Crossman, Ying Si, Matthew S. Alexander, Merry‐Lynn N. McDonald, Peter H. King, Michael A. Lopez

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518 Modeling of cancer mutations found in pediatric DICER1 syndrome informs novel therapeutic targeting strategies by David Jee, Seungjae Lee, Dapeng Yang, Robert Rickert, Renfu Shang, Danwei Huangfu, Eric C. Lai

“…Objectives/Goals: Large-scale tumor sequencing efforts have led to annotations of novel cancer hotspot mutations that may underlie driver or cooperative function. We have sought to define the molecular consequences of such hotspots associated with pediatric DICER1 syndrome cancers, with the ultimate goal of revealing novel targets that may inform new standards of care. …”
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Cellpose as a reliable method for single-cell segmentation of autofluorescence microscopy images by Jeremiah M. Riendeau, Amani A. Gillette, Emmanuel Contreras Guzman, Mario Costa Cruz, Aleksander Kralovec, Shirsa Udgata, Alexa Schmitz, Dustin A. Deming, Beth A. Cimini, Melissa C. Skala

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A Validation Tool (VaPCE) for Postcoordinated SNOMED CT Expressions: Development and Usability Study by Tessa Ohlsen, Viola Hofer, Josef Ingenerf

“… Abstract BackgroundThe digitalization of health care has increased the demand for efficient data exchange, emphasizing semantic interoperability. …”
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A Qualitative Study Examining the Unintended Consequences from Implementing a Case Management Team to Reduce Avoidable Hospital Readmission in Singapore by Shilpa Surendran, Stephen So, Toon Wei Lim, David Bruce Matchar

“…Results: Data analysis generated seven subthemes: ineffective targeting of patient population, fund constraints, lack of patient ownership, limited post discharge follow up, comprehensive care approaches, role overlap and patient confusion. …”
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Zebrafish do not have a calprotectin ortholog. by Kona N Orlandi, Michael J Harms

“…The field would benefit from expanding the breadth of calprotectin studies into a zebrafish innate immunity model. Here, we carefully evaluated the possibility that zebrafish possess a calprotectin ortholog or a paralog that convergently evolved similar function. …”
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Costs and acceptability of simplified monitoring in HIV-suppressed patients switching to dual therapy: the SIMPL’HIV open-label, factorial randomised controlled trial by Annalisa Marinosci, Delphine Sculier, Gilles Wandeler, Sabine Yerly, Marcel Stoeckle, Enos Bernasconi, Dominique L. Braun, Pietro Vernazza, Matthias Cavassini, Marta Buzzi, Karin J. Metzner, Laurent Decosterd, Huldrych F. Günthard, Patrick Schmid, Andreas Limacher, Mattia Branca, Alexandra Calmy

“… BACKGROUND: Clinical and laboratory monitoring of patients on antiretroviral therapy is an integral part of HIV care and determines whether treatment needs enhanced adherence or modification of the drug regimen. …”
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Clinical and cost-effectiveness of non-medical prescribing: A systematic review of randomised controlled trials. by Timothy Noblet, John Marriott, Emma Graham-Clarke, Debra Shirley, Alison Rushton

“…Measurements reported on one or more outcome(s) of: pain, function, disability, health, social impact, patient-safety, costs-analysis, quality adjusted life years (QALYs), patient satisfaction, clinician perception of clinical and functional outcomes.…”
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Macrophage-derived exosomes in cancer: a double-edged sword with therapeutic potential by Long Liu, Siying Zhang, Yuqing Ren, Ruizhi Wang, Yuyuan Zhang, Siyuan Weng, Zhaokai Zhou, Peng Luo, Quan Cheng, Hui Xu, Yuhao Ba, Anning Zuo, Shutong Liu, Zaoqu Liu, Xinwei Han

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Chaperone-Mediated Responses and Mitochondrial–Endoplasmic Reticulum Coupling: Emerging Insight into Alzheimer’s Disease by Manish Kumar Singh, Minghao Fu, Sunhee Han, Jyotsna S. Ranbhise, Wonchae Choe, Sung Soo Kim, Insug Kang

“…This review focuses on the relationship between stress chaperone responses and organelle function, particularly the interaction between mitochondria and the ER, in the development of new therapies for AD and related neurodegenerative disorders.…”
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Virtual stressors with real impact: what virtual reality-based biobehavioral research can teach us about typical and atypical stress responsivity by Elizabeth A. Shirtcliff, Tor T. Finseth, Eliot H. Winer, David C. Glahn, Roselynn A. Conrady, Stacy S. Drury

“…Binary thinking about whether something is (not) real has stifled advances in understanding how to measure the dosage of a stressful environment. As a function of being programmed, individualizable, and titrated, virtual reality (VR) based stressors offer the field a platform for quantifying the dose of a stressor and generating reliable dose-response curves. …”
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Pathogenesis of Cardiac Depression in Acute Destructive Pancreatitis by A. V. Ershov, V. T. Dolgikh, O. V. Korpacheva, V. V. Rusakov, N. I. Taran, N. S. Gritsenko

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