A Survey of 5G Core Network User Identity Protections, Concerns, and Proposed Enhancements for Future 6G Technologies by Paul Scalise, Michael Hempel, Hamid Sharif

“…Fifth-Generation (5G) cellular networks extensively utilize subscriber identifiers throughout the protocol stack, thereby linking subscribers to their activities on the network. …”
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Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT by Neil McHugh, Laura Bojke, Mel Brooke Turfrey, Rachel Charlton, Myka Ransom, Laura C Coates, Howard Collier, Claire Davies, Emma Dures, Philip Helliwell, Jana James, Anya Lissina, Vishnu B Madhok, Alison L Nightingale, Jonathan Packham, Catherine Smith, Eldon Spackman, Cerys Tassinari, William Tillett, Sarah T Brown

“…Conclusion The benefit of early detection of psoriatic arthritis in a primary care psoriasis population remains unproven. Surveillance for undiagnosed psoriatic arthritis generally detects mild cases as measured by physical function. …”
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Efficacy of Combined High-Intensity Laser Therapy and Collagenase Chemonucleolysis in Lumbar Disc Herniation Management: a Prospective Randomized Controlled Trial by Peng Song, Chao Ma, Chenchen Xu, Yongjun Zhang, Yan Yuan

“…Conclusions Our findings demonstrate that high-intensity laser therapy augmentation of collagenase chemonucleolysis significantly improves early postoperative pain and functional outcomes in patients with lumbar disc herniation. …”
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Dynamic URP: Revisiting Urethral Retro-Resistance Pressure for Contemporary Sphincter-Targeted Therapy by Nicole Fleischmann

“…ΔURP has the potential to revive and repurpose a once-abandoned method into a clinically actionable biomarker for next-generation continence care.…”
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BioImpedance Spectroscopy to maintain Renal Output: the BISTRO randomised controlled trial by Simon J Davies, David Coyle, Elizabeth Lindley, David Keane, John Belcher, Fergus Caskey, Indranil Dasgupta, Andrew Davenport, Ken Farrington, Sandip Mitra, Paula Ormandy, Martin Wilkie, Jamie MacDonald, Mandana Zanganeh, Lazaros Andronis, Ivonne Solis-Trapala, Julius Sim

“…The primary outcome was time to anuria; secondary outcomes were rate in decline of residual kidney function, blood pressure, dialysis-related symptoms (Integrated Palliative Care Outcome Scale-Renal), quality of life (EuroQol) and incremental cost per additional quality-adjusted life-year gained. …”
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Hybridization Chain Reaction-Enhanced Ultrasensitive Electrochemical Analysis of miRNAs with a Silver Nano-Reporter on a Gold Nanostructured Electrode Array by Bin Wang, Huiqiang Ma, Mingxing Zhou, Xian Huang, Ying Gan, Hong Yang

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Harnessing Digital Health Technologies to Combat Climate Change‐Related Health Impacts by Yuhang Li, Ge Wu, Puxi Gong, Chang Liu, Lizhong Liang, Mengchun Gong, Zhirong Zeng

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Designing and validating a clinical decision support algorithm for diabetic nephroprotection in older patients by Simon LeClerc, Nicolas Fernandez, Kelley Kilpatrick, Cheryl Sadowski, Noor Alsalemi, Naoual Elftouh, Jean-Philippe Lafrance, Sherilyn Houle

“…The aim of this research is to design and validate a CDS algorithm for prescribing renin-angiotensin-aldosterone system inhibitors (RAASi) for older patients with diabetes.Methods The design of the CDS tool included the following phases: (1) gathering evidence from systematic reviews and meta-analyses of randomised clinical trials to determine the number needed to treat (NNT) and time-to-benefit (TTB) values applicable to our target population for use in the algorithm. (2) Building a list of potential cases that addressed different prescribing scenarios (starting, adding or switching to RAASi). (3) Reviewing relevant guidelines and extracting all recommendations related to prescribing RAASi for DKD. (4) Matching NNT and TTB with specific clinical cases. (5) Validating the CDS algorithm using Delphi technique.Results We created a CDS algorithm that covered 15 possible scenarios and we generated 36 personalised and nine general recommendations based on the calculated and matched NNT and TTB values and considering the patient’s life expectancy and functional capacity. …”
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Lessons From Gattinoni by Andrea Castellví-Font, MD, Tai Pham, MD, PhD, Bhakti Patel, MD, Eddy Fan, MD, PhD

“…Through his relentless pursuit of integrating respiratory physiology into clinical practice, Professor Gattinoni inspired generations of clinicians and researchers, leaving an indelible legacy that continues to guide advancements in critical care worldwide.…”
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Severe Uncompensated Metabolic Alkalosis due to Plasma Exchange in a Patient with Pulmonary-Renal Syndrome: A Clinician’s Challenge by Mohsin Ijaz, Naeem Abbas, Dmitry Lvovsky

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The comparative effects of injecting intra-articular platelet-rich plasma and hypertonic dextrose prolotherapy in osteoarthritis knee - A randomized control trial by Neeraj Singh, Anil K. Gupta, Dileep Kumar, Sudhir Mishra, Ganesh Yadav, Shreya Singh

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Sex, diabetes status and cognition: findings from the study of longevity in diabetes by Mary E Lacy, Paola Gilsanz, Michal S Beeri, Rachel A Whitmer, Chris Moran

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Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction by Lisa Willemsen, Myrthe den Toom, Myrthe E Reiche, Marion J J Gijbels, Esther Lutgens, Bram van Os, Norbert Gerdes, Suzanne A B M Aarts

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Design and virtual implementation of a biomedical registry framework for the enhancement of clinical trials: colorectal cancer example by Athanasios Kotoulas, George Lambrou, Dimitrios-Dionysios Koutsouris

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The curious case of extinction of family physicians from the Indian Health System – An open letter to the members of the National Medical Commission: Draft competency-based medical... by Raman Kumar

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Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review by Joy Duxbury, Alina Haines-Delmont, John Baker, Peter Baker, Gary Bourlet, Elaine Craig, James Ridley, Rachel Whyte, Beth Morrison, Michaela Thomson, Anthony Tsang, Tella Lantta

“…Funding This award was funded by the National Institute for Health and Care Research (NIHR) Health and Social Care Delivery Research programme (NIHR award ref: NIHR129524) and is published in full in Health and Social Care Delivery Research; Vol. 13, No. 14. …”
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Analgesic efficacy and safety of erector spinae plane block versus serratus anterior plane block in breast surgery—a meta-analysis and systematic review of randomized controlled tr... by Samiullah Shaikh, Umm E Salma Shabbar Banatwala, Paranshi Desai, Muhammad Arham Khan, Rimsha Bint-e-Hina, Sidra Samad, Muhammad Hamza Sikandari, Ali Nawaz, Rana Ijaz, Shayan Asmat, Abeer Fatima, Harim Mirza, Noor Mahal Azam, Qurat Ul Ain Muhammad, Satesh Kumar, Mahima Khatri

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Resolution of Sterile Inflammation: Role for Vitamin C by Bassem M. Mohammed, Bernard J. Fisher, Quoc K. Huynh, Dayanjan S. Wijesinghe, Charles E. Chalfant, Donald F. Brophy, Alpha A. Fowler III, Ramesh Natarajan

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Living with, managing and minimising treatment burden in long term conditions: a systematic review of qualitative research. by Sara Demain, Ana-Carolina Gonçalves, Carlos Areia, Rúben Oliveira, Ana Jorge Marcos, Alda Marques, Ranj Parmar, Katherine Hunt

“…<h4>Background</h4>'Treatment burden', defined as both the workload and impact of treatment regimens on function and well-being, has been associated with poor adherence and unfavourable outcomes. …”
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Carbon monoxide as a cellular protective agent in a swine model of cardiac arrest protocol. by John C Greenwood, Ryan W Morgan, Benjamin S Abella, Frances S Shofer, Wesley B Baker, Alistair Lewis, Tiffany S Ko, Rodrigo M Forti, Arjun G Yodh, Shih-Han Kao, Samuel S Shin, Todd J Kilbaugh, David H Jang

“…Out-of-hospital cardiac arrest (OHCA) affects over 360,000 adults in the United States each year with a 50-80% mortality prior to reaching medical care. Despite aggressive supportive care and targeted temperature management (TTM), half of adults do not live to hospital discharge and nearly one-third of survivors have significant neurologic injury. …”
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