Transfusion Therapy in Critically Ill Children by Tai-Tsung Chang

“…The characteristics of hemorrhagic diseases are so varied that their therapy should depend on the specific needs associated with the underlying disease. In general, platelet transfusion is not needed when a patient has platelet count greater than 10,000/mm3 and is without active bleeding, platelet functional deficiency or other risk factors such as sepsis. …”
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The Impact of Chronic Pelvic Pain and Bowel Morbidity on Quality of Life in Cervical Cancer Patients Treated With Radio (Chemo) Therapy. A Systematic Literature Review by Natuhwera G, Ellis P

“…There is limited population-based and longitudinal research about the topic, and on chronic pelvic pain in general, which limits generalisability. Longitudinal studies with more extended periods of follow-up are needed.Keywords: chronic pelvic pain, bowel morbidity, cervical cancer, quality of life, radio (chemo) therapy…”
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Intraoperative low-dose esketamine on postoperative quality of recovery in patients undergoing open gynecologic surgery: a double-blinded, parallel-group, placebo- controlled trial by Zhi-Yu Geng, Yan Zhang, Xin Yan, Jun Hu, Ran Cui, Lin-Lin Song, Hui-Cheng Song

“…We aimed to evaluate the effect of low-dose esketamine on quality of recovery when used as part of multimodal analgesia in patients undergoing open gynecologic surgery.Methods 140 female patients undergoing gynecologic laparotomy under general anesthesia were randomly assigned to receive intraoperative infusion of either 0.25 mg/kg/h esketamine (study group) or an equivalent volume of normal saline (control group). …”
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Towards a definition of refractory/therapy-resistant/intractable constipation in children: a cross-sectional, questionnaire-based, online survey by Marc A Benninga, Morris Gordon, Shaman Rajindrajith, Vassiliki Sinopoulou, Merit Tabbers, Carlos Velasco, Wathsala Hathagoda, Mansour Abdulshafea

“…Background The Rome criteria define childhood functional constipation but do not address refractory constipation. …”
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User Acceptance of a Home Robotic Assistant for Individuals With Physical Disabilities: Explorative Qualitative Study by Linda Sørensen, Dag Tomas Sagen Johannesen, Helinä Melkas, Hege Mari Johnsen

“… BackgroundHealth care is shifting toward 5 proactive approaches: personalized, participatory, preventive, predictive, and precision-focused services (P5 medicine). …”
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Interpretation and classification of FBN1 variants associated with Marfan syndrome: consensus recommendations from the Clinical Genome Resource’s FBN1 variant curation expert panel... by A. Drackley, C. Somerville, P. Arnaud, L. M. Baudhuin, N. Hanna, M. L. Kluge, K. Kotzer, C. Boileau, L. Bronicki, B. Callewaert, A. Cecchi, H. Dietz, D. Guo, S. Harris, O. Jarinova, M. Lindsay, L. Little, B. Loeys, G. MacCarrick, J. Meester, D. Milewicz, T. Morisaki, H. Morisaki, D. Murdock, M. Renard, J. Richer, L. Robert, M. Ouzounian, L. Van Laer, J. De Backer, L. Muiño-Mosquera

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Evaluating the effect of immune checkpoint inhibitor treatment on chronic obstructive pulmonary disease in lung cancer patients by Anet Greib, Songzhu Zhao, Michelle Ploch, Jonathan Henricks, Robert Easterling, Meghana Moodabagil, Gabrielle Lopez, Mingjia Li, Evelyn G. Goodyear, John Sharp, Asrar Alahmadi, Jacob Kaufman, Regan Memmott, Kai He, Peter Shields, David P. Carbone, Gregory A. Otterson, Carolyn J. Presley, Lai Wei, Dwight H. Owen, Kevin Ho

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Augmenting neurocognitive remediation therapy to Preventive Cognitive Therapy for partially remitted depressed patients: protocol of a pragmatic multicentre randomised controlled t... by Huibert Burger, Claudi Bockting, Marlies Brouwer, Gert J Geurtsen, Amanda M Legemaat, Johanne G J van der Stappen, Maria Semkovska, Isidoor O Bergfeld, Nicoline Lous, Damiaan A J P Denys

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Evaluating the Effectiveness of an Intelligent mHealth Intervention for Child Unintentional Injury Prevention: Protocol for a Cluster Randomized Controlled Trial by Yang Yuan, Yuying Jing, Jiyu Li, Jieyi He, David C Schwebel, Peishan Ning, Zhenzhen Rao, Li Li, Guoqing Hu

“…Data analysis will be conducted using generalized linear mixed models with a Poisson link function and generalized estimating equations to assess the effectiveness of the iCURE intervention, following intention-to-treat principles. …”
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Cardiovascular Prehabilitation in Patients Awaiting Heart Transplantation— Addressing Clinical Needs (the PREHAB HTx Study) by Jennifer L. Reed, R. Kin, PhD, Heather E. Tulloch, PhD, Heather Ross, MD, Tasuku Terada, PhD, Matheus Mistura, MSc, Isabela Roque Marçal, MSc, Paul Oh, MD, Sharon Chih, MBBS, PhD

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Optimization of the treatment of patients with severe chronic urticaria by Ye.M. Dytiatkovska, N.O. Nedohybchenko

“…After the completion of treatment in patients of Group 2, nine weeks after the initiation of desloratadine therapy according to the SKINDEX-29 questionnaire, 44% of cases and 46% of very severe negative effects of urticaria on the emotional sphere and functioning remained, respectively; and in 46% of cases there was a low quality of life according to the generalized assessment of the impact of the disease at the level of "severe". …”
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Biotin interference in routine clinical immunoassays by Kuo-Chun Chiu, Jia-Rong Jhan, Hsiao-Ni Yan, Yu-Chen Liao, Wen-Hui Lu, Kuan-Yi Lee, Li-Yuan Cheng, Chung-Kang Yeh, Ya-Fen Lee, Chiung-Hui Kuo, Kuei-Pin Chung, Tzu-I Chien

“…Studies have documented biotin's significant impact on thyroid function tests and various immunoassays, prompting the need for effective mitigation strategies. …”
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Exploring NUP62’s role in cancer progression, tumor immunity, and treatment response: insights from multi-omics analysis by Lihong Chen, Youfu He, Menghui Duan, Tianwen Yang, Yin Chen, Bo Wang, Dejun Cui, Chen Li

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Fluoride Release from Pediatric Dental Restorative Materials: A Laboratory Investigation by Angelo Aliberti, Roberta Gasparro, Maria Triassi, Mirko Piscopo, Pietro Ausiello, João Paulo Mendes Tribst

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The relationship between cardiometabolic Index and diabetic kidney disease in people with diabetes by Jianping Kong, Wenting Tao, Yuhong Sun, Yong Xu, Hailun Li, Jing Li

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The importance of measuring the levels of ionized magnesium in the blood in critically ill patients by Stanojević Marija B., Parezanovic Miro, Biorac Marko, Spasić Svetolik, Kovačević Sanjin, Lopičić Srđan, Nešović Ostojić Jelena

“…Magnesium is a bioessential element with multiple physiological effects relevant for vital body functions. It stabilizes excitable membranes contributing to proper neuromuscular, cardiovascular and respiratory functions. …”
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Subjective wellbeing of primary healthcare patients in the Western Cape, South Africa by Marieanna C. le Roux, Ashraf Kagee, Marie van der Merwe, Fatima Parker

“…Participants were asked to complete a questionnaire battery consisting of the Satisfaction with Life Scale, the Coping Strategy Indicator, the Functioning Assessment of Non-Life Threatening Conditions and the Perceived Social Support Scale. …”
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Is physical therapy recommended for people with parkinson’s disease treated with subthalamic deep brain stimulation? a delphi consensus study by Matteo Guidetti, Sara Marceglia, Tommaso Bocci, Ryan Duncan, Alfonso Fasano, Kelly D. Foote, Clement Hamani, Joachim K. Krauss, Andrea A. Kühn, Francesco Lena, Patricia Limousin, Andres M. Lozano, Natale V. Maiorana, Nicola Modugno, Elena Moro, Michael S. Okun, Serena Oliveri, Marco Santilli, Alfons Schnitzler, Yasin Temel, Lars Timmermann, Veerle Visser-Vandewalle, Jens Volkmann, Alberto Priori

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Experience with the interleukin 6 inhibitor (Olokizumab) in patients with rheumatoid arthritis in real clinical practice: Influence on inflammatory activity and disease outcomes by N. A. Lapkina, A. A. Baranov, N. E. Abaytova, E. A. Leontyeva, N. V. Yaltseva, A. S. Shutov, E. L. Nasonov

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PTSD Coach as an early mobile intervention to improve cancer-related anxiety and psychosocial oncology uptake in patients newly diagnosed with head and neck cancer: pilot randomize... by Laurence Ducharme, Chris Lo, Michael Hier, Anthony Zeitouni, Karen Kost, Alex Mlynarek, Michael Antoni, Eric Kuhn, Jason E. Owen, Daren Heyland, Robert Platt, Fabienne Fuehrmann, Nader Sadeghi, Zeev Rosberger, Saul Frenkiel, Khalil Sultanem, George Shenouda, Fabio Cury, Melissa Henry

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