Smart transplants: emerging role of nanotechnology and big data in kidney and islet transplantation, a frontier in precision medicine by Rajkiran Deshpande, Titus Augustine, Titus Augustine

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Assessing the quality of life of adolescents with sickle cell disease and their transition to adult medicine: experience in a remote area of the Democratic Republic of Congo by Benoît Mbiya-Mukinayi, Corneille Kalala-Mushinta, Schadrac Kalombo-Munganga, Alexandre Kalala-Mwanza, Steve Kasongo-Tshiala, John Mpoyi-Kalenda, Béatrice Gulbis

“…The majority, 92% of the adolescents, were unaware of the transition, and 68% did not feel ready to move from pediatric care to adult care. Conclusion These findings highlight the importance of considering the quality of life of sickle cell adolescents and their transition to adult medicine in Mbujimayi, highlighting the challenges they face and the factors that affect their well-being in general. …”
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Model of quality of life in a group of people with chronic low back pain by Urszula Ziętalewicz, Kamilla Bargiel-Matusiewicz

“…We conducted a cross-sectional study in which a multi-module self-administered questionnaire examining biological factors, personality traits, personal values, body assessment, symptoms of depression and anxiety, functional status, general perception of health, life satisfaction, received social support, economic support, satisfaction of health care and sociodemographic factors was adopted. …”
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A Triple Threat: A Case Report Detailing Surgical Management for Hypertrophic Cardiomyopathy, Flail Mitral Valve and Severe Pulmonary Hypertension by Cass G. G. Sunga, Kai-Chun Yang, Shakirat Oyetunji, Erik R. Swenson, Kavita Khaira

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DIRECTIONS FOR IMPROVING THE QUALITY OF POSTGRADUATE EDUCATION OF PHYSICIANS by Н. Каспрук, С. Батрановська, С. Мельничук, Т. Унгурян, Т. Копчук, А. Петрюк

“…The study encompassed various specialties, including General Practice–Family Medicine, Dermatovenereology, Anesthesiology and Intensive Care, and Dentistry. …”
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Risk factors for voriconazole-associated hepatotoxicity in patients with liver dysfunction: a retrospective nested case–control study by Jing Ren, Xinfeng Cai, Wei Ge, Jinlin Guo, Shan Wang, Qinhui Wang, Linna Liu, Le Yang, Qi Yang

“…The univariate analysis revealed trough voriconazole plasma concentration (VPC), voriconazole treatment duration, activated partial thromboplastin time, and intensive care unit admission as variables for the final analysis. …”
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Mobile health-based remote interaction management intervention for patients with low anterior resection syndrome: study protocol for a randomised controlled trial by Ting Wang, Peng Zhou, Min Fu, Shihui Yu, Shaohua Hu, Hongye He, Xueying Pang, Danqiao Yin, Degang Zhu

“…The improvement of LARS largely depends on patient self-management behaviour; however, insufficient information about supportive care and weak awareness of self-management lead to poor self-management behaviour. …”
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Mortality and exacerbation risk according to GOLD and STAR severity stages of COPD: a 5-year multicenter prospective cohort study by Hiroaki Ogata, Kazuya Tsubouchi, Tomotsugu Takano, Katsuyuki Ichiki, Ryo Torii, Shohei Takata, Noriaki Nakagaki, Makoto Yoshida, Yasuhiko Kitasato, Kazunori Tobino, Eiji Harada, Hiroshi Wataya, Hiroshi Ishii, Takashige Maeyama, Masayuki Kawasaki, Masaki Fujita, Kazuhiro Yatera, Yoshiaki Zaizen, Yoichi Nakanishi, Isamu Okamoto

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Development of an electrocardiographic prediction model for outflow tract idiopathic premature ventricular contraction with decreased left ventricular ejection fraction by Pinliang Liao, Xiaolian Cai, Wen Zhang, Min Ou, Heling Ren, Maoqin Shu

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Shear Stress Triggers Angiogenesis of Late Endothelial Progenitor Cells via the PTEN/Akt/GTPCH/BH4 Pathway by Shao-Hong Wu, Feng Zhang, Shun Yao, Lu Tang, Hai-Tao Zeng, Ling-Ping Zhu, Zhen Yang

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Healthcare utilization and disease burden in children with metachromatic leukodystrophy in Germany by Christiane Kehrer, Andrea Bevot, Pascal Martin, Christa Raabe, Saskia Gregor, Ingeborg Krägeloh-Mann, Samuel Groeschel

“…Gallbladder polyposis was seen in 52%. General well-being did not strongly correlate with motor function, whereas pain was associated with reduced well-being. …”
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Heart remodeling in patients with acute Q-wave myocardial infarction in the presence of left bundle branch block by V. D. Syvolap, Ya. V. Zemlyaniy

“…Abstract The prevalence of left bundle branch block (LBBB) in the general population is 0.1–0.8 %, and in patients with ST-segment elevation Q-wave myocardial infarction (Q-MI) varies from 1 % to 15 %. …”
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Current Evidence on the Usefulness of Potential Therapies in the Prevention of COPD Exacerbations: Beyond the Use of Bronchodilator Therapy and Inhaled Corticosteroids by Juan Marco Figueira-Gonçalves, Francisco Javier Callejas-González, Rafael Golpe, Luis Máiz-Carro, Marta Marín-Oto, Javier de Miguel-Díez, Guillermo Samuel Loscertales-Vacas, José María Tordera-Mora, Álvaro Hurtado-Fuentes

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Can electronic monitoring with a digital smart spacer support personalised medication adherence and inhaler technique education in patients with asthma?: Protocol of the randomised... by Job F. M. van Boven, Boudewijn H.J. Dierick, Maria Achterbosch, Sandra Been-Buck, Titia Klemmeier, Susanne J. van de Hei, Paul Hagedoorn, Huib A.M. Kerstjens, Janwillem W.H. Kocks

“…After 1 month (t=0), patients are 1:1 randomised into two groups: control group (usual care) versus intervention group (personalised education). …”
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A study protocol of a comparative mixed study of the T‐Control catheter by José Medina‐Polo, Ana Belén Salamanca‐Castro, Yolanda Ramallo‐Fariña, Max Mòdol‐Vidal, Cristina Valcárcel‐Nazco, Clara Armas‐Moreno, Lilisbeth Perestelo‐Pérez, Lidia García‐Pérez, Miguel Ángel García‐Bello, Manuel Luque‐González, Marta Serrano‐Muñoz, Santiago Pérez‐García

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A phase I / IIa trial of PXS-5505, a novel pan-lysyl oxidase inhibitor, in advanced myelofibrosis by Pankit Vachhani, Peter Tan, Anne-Marie Watson, Shang-Ju Wu, Ross Baker, Stanley Cheung, Sung-Eun Lee, Chih-Cheng Chen, Tsai-Yun Chen, Hui-Hua Hsiao, Jae Hoon Lee, Lucia Masarova, Shuh Ying Tan, Jana Baskar, Brett Charlton, Alison Findlay, Dieter Hamprecht, Wolfgang Jarolimek, Joanna Leadbetter, John Miller, Kristen Morgan, Amna Zahoor, Gabriela Hobbs

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Ketogenic diet in treating sepsis-related acquired weakness: is it friend or foe? by Yanmei Miao, Leiyu Xie, Shaolin Chen, Xiaoming Zhang, Wenjie Liu, Peng Xie, Peng Xie

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Acute kidney injury in patients treated with immune checkpoint inhibitors by Joe-Elie Salem, Enriqueta Felip, Sophie Papa, Shuchi Anand, Karolina Benesova, Marlies Ostermann, Ala Abudayyeh, Omar Mamlouk, Umut Selamet, Grace Cherry, Sunandana Chandra, Sandra M Herrmann, Maria Jose Soler, Abhijat Kitchlu, Jamie S Lin, Kerry L Reynolds, Osama E Rahma, Elizabeth M Gaughan, Eva Muñoz-Couselo, Jamie S Hirsch, Pablo Garcia, Meghan D Lee, Harish Seethapathy, Ian A Strohbehn, Meghan E Sise, Wei-Ting Chang, Els Wauters, Lucy Flanders, Deborah Schrag, Thibaud Koessler, Mark Eijgelsheim, Shruti Gupta, Frank B Cortazar, Samuel A P Short, Jason M Prosek, Sethu M Madhavan, Ilya Glezerman, Shveta S Motwani, Naoka Murakami, Rimda Wanchoo, David I Ortiz-Melo, Arash Rashidi, Ben Sprangers, Vikram Aggarwal, A Bilal Malik, Sebastian Loew, Christopher A Carlos, Pazit Beckerman, Zain Mithani, Chintan V Shah, Amanda D Renaghan, Sophie De Seigneux, Luca Campedel, Daniel Sanghoon Shin, Sunil Rangarajan, Priya Deshpande, Gaia Coppock, Dwight H. Owen, Marium Husain, Clara Garcia-Carro, Sheila Bermejo, Nuttha Lumlertgul, Nina Seylanova, Busra Isik, Aydin Kaghazchi, Yuriy Khanin, Sheru K Kansal, Kai M Schmidt-Ott, Raymond K Hsu, Maria C Tio, Suraj Sarvode Mothi, Harkarandeep Singh, Kenar D Jhaveri, David E Leaf, Corinne Isnard Bagnis, Suraj S Mothi, Weiting Chang, Vipulbhai Sakhiya, Daniel Stalbow, Sylvia Wu, Armando Cennamo, Anne Rigg, Nisha Shaunak, Zoe A Kibbelaar, Harish S Seethapathy, Meghan Lee, Ian A Strohbhen, Ilya G Glezerman, Dwight H Owen, Sharon Mini, Andrey Kisel, Nicole Albert, Katherine Carter, Vicki Donley, Tricia Young, Heather Cigoi, Els Wauters Ben Sprangers, Javier A Pagan, Jonathan J Hogan, Valda Page, Samuel AP Short, A Bilal Malik, Maria Josep Carreras

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Non-clinical factors influencing discharge and admission decisions in the emergency department: a focus group study among Israeli physicians by Ofer Kobo, Itay Itzhaki, Michael J. Drescher, Jacob Glazer, Avi Israeli, Bruce E. Landon, Shuli Brammli-Greenberg

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Anesthetic Management of the Pregnant Patient Undergoing Non-Obstetric Surgery by Genevieve Monanian, Seth Greenspan, Nadir Khan Yusufzai, Bahaa Daoud, Zhaosheng Jin, Morgane Factor

“…Key factors include appropriate drug selection to minimize fetal exposure, maintenance of uteroplacental perfusion, and management of physiological changes associated with pregnancy, such as altered respiratory function and increased blood volume. Regional anesthesia is often preferred to reduce the risks of general anesthesia, although considerations such as positioning, airway management, and monitoring are crucial. …”
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