Showing 781 - 800 results of 2,136 for search 'care function general', query time: 0.21s Refine Results
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    Towards a novel framework for identifying commonalities and differences in older people’s end-of-life trajectories: aims and interdisciplinary mixed-methods approach of the ERC-fun... by Khyati Tripathi, Emma Gobiet, Lieve Van den Block, Casper Van den Bossche, Lara Pivodic

    Published 2024-12-01
    “…Our understanding of these end-of-life trajectories is very limited, focuses predominantly on physical function and clinical predictors and neglects inter-individual differences. …”
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    Incidence and risk factors for mortality and end-stage renal disease in people with type 2 diabetes and diabetic kidney disease: a population-based cohort study in the UK by Marcus Lind, Antonio González-Pérez, David Vizcaya, Maria Saez, Luis Garcia Rodriguez

    Published 2021-03-01
    “…Introduction We aimed to determine the incidence of, and risk factors for all-cause/cardiovascular disease (CVD) mortality, and end-stage renal disease (ESRD) among people with type 2 diabetes with/without diabetic kidney disease (DKD) in the UK general population.Research design and methods We undertook a population-based cohort study using primary care UK electronic health records. …”
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    Designing and validating a clinical decision support algorithm for diabetic nephroprotection in older patients by Simon LeClerc, Nicolas Fernandez, Kelley Kilpatrick, Cheryl Sadowski, Noor Alsalemi, Naoual Elftouh, Jean-Philippe Lafrance, Sherilyn Houle

    Published 2024-09-01
    “…The aim of this research is to design and validate a CDS algorithm for prescribing renin-angiotensin-aldosterone system inhibitors (RAASi) for older patients with diabetes.Methods The design of the CDS tool included the following phases: (1) gathering evidence from systematic reviews and meta-analyses of randomised clinical trials to determine the number needed to treat (NNT) and time-to-benefit (TTB) values applicable to our target population for use in the algorithm. (2) Building a list of potential cases that addressed different prescribing scenarios (starting, adding or switching to RAASi). (3) Reviewing relevant guidelines and extracting all recommendations related to prescribing RAASi for DKD. (4) Matching NNT and TTB with specific clinical cases. (5) Validating the CDS algorithm using Delphi technique.Results We created a CDS algorithm that covered 15 possible scenarios and we generated 36 personalised and nine general recommendations based on the calculated and matched NNT and TTB values and considering the patient’s life expectancy and functional capacity. …”
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