Comparison between the EKFC-equation and machine learning models to predict Glomerular Filtration Rate by Felipe Kenji Nakano, Anna Åkesson, Jasper de Boer, Klest Dedja, Robbe D’hondt, Fateme Nateghi Haredasht, Jonas Björk, Marie Courbebaisse, Lionel Couzi, Natalie Ebert, Björn O. Eriksen, R. Neil Dalton, Laurence Derain-Dubourg, Francois Gaillard, Cyril Garrouste, Anders Grubb, Lola Jacquemont, Magnus Hansson, Nassim Kamar, Christophe Legendre, Karin Littmann, Christophe Mariat, Toralf Melsom, Lionel Rostaing, Andrew D. Rule, Elke Schaeffner, Per-Ola Sundin, Arend Bökenkamp, Ulla Berg, Kajsa Åsling-Monemi, Luciano Selistre, Anders Larsson, Ulf Nyman, Antoine Lanot, Hans Pottel, Pierre Delanaye, Celine Vens

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Strong Hsp90α/β Protein Expression in Advanced Primary CRC Indicates Short Survival and Predicts Response to the Hsp90α/β-Specific Inhibitor Pimitespib by Sebastian B. M. Schmitz, Jakob Gülden, Marlene Niederreiter, Cassandra Eichner, Jens Werner, Barbara Mayer

“…The anti-cancer effect and chemosensitization of Pim-based therapy were prospectively confirmed in PDCS directly generated from Hsp90α/β > 40% pCRCs. Protein profiling combined with functional drug testing stratifies Hsp90α/β > 40% pCRC patients diagnosed with UICC IIb-IV for effective Pim-based therapy.…”
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Hydrogel‐embedded precision‐cut lung slices support ex vivo culture of in vivo‐induced premalignant lung lesions by Caroline Hauer, Rachel Blomberg, Kayla Sompel, Chelsea M. Magin, Meredith A. Tennis

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Value of Probiotics on Outcome in Patients Following Liver Surgery: A Systematic Review and Meta-Analysis by Robert Karitnig, Andreas Bogner, Nora Jahn, Christos Vlachos, Andri Lederer, Antonia Geisler, Robert Sucher, Hans Michael Hau

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Monocyte‐Derived Macrophages Induce Alveolar Macrophages Death via TNF‐α in Acute Lung Injury by Junjie Xiao, Fei Hou, Huan Wang, Ruixuan Wang, Ying Liu, Xiayan Wu, Lixin Xie

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Application of Macrophage Subtype Analysis in Acute Lung Injury/Acute Respiratory Distress Syndrome by Jiajia Tang, Jun Shi, Zhihai Han, Xuxin Chen

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Mitochondrial oxygen metabolism as a potential predictor of weight loss after laparoscopic sleeve gastrectomy for class III obesity by Markus Engelmann, Markus Engelmann, Juliane Götze, Juliane Götze, Philipp Baumbach, Philipp Baumbach, Charles Neu, Charles Neu, Utz Settmacher, Michael Ardelt, Hermann Kissler, Sina M. Coldewey, Sina M. Coldewey

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Constipations in elderly: diagnostics and treatment approach by Yu. O. Shulpekova

“…To illuminate principal causes and features of manifestations of constipation at elderly patients, to present a general investigation and treat- ment plan.Original positions. …”
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Chest wall strapping in a porcine model: A model for the physiology of the oversized lung allograft by Eric Abston, Michael Eberlein

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Evaluating the efficacy of Internet-Based Exercise programme Aimed at Treating knee Osteoarthritis (iBEAT-OA) in the community: a study protocol for a randomised controlled trial by Abhishek Abhishek, Sameer Akram Gohir, Paul Greenhaff, Ana M. Valdes

“…This study aims to explore the benefits of iBEAT-OA (Internet-Based Exercise programme Aimed at Treating knee Osteoarthritis) in modulating pain, function and other health-related outcomes in individuals with knee OA.Methods and analysis A randomised controlled trial was designed to evaluate the efficacy of a web-based exercise programme in a population with knee OA compared with standard community care provided by general practitioners (GPs) in the UK. …”
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PREVENTION OF STROKE IN ATRIAL FIBRILLATION: THE APPROACHES TO THE CHOICE OF ANTICOAGULANT, DEPENDING ON AGE by A. V. Ardashev, I. V. Zotova

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Impact of acute and chronic regular exercise on arterial stiffness and reflection measures in coronary artery disease patients: A Protocol for Randomized Clinical Trial by G. Kapoor, A. Swaroop, S. Singh

“…The study will be conducted at a tertiary care hospital for a continuous period of one year. …”
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Effects of Physical Exercises in Asthma: An Umbrella Review of Systematic Review and Meta‐Analysis by Fuchun Huang, Shuang Yang, Mingxuan Ma, Jialin Zhang, Hua Liu

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Non-invasive Respiratory Support in Blunt Chest Injury by T. V. Lobus, Yu. V. Marchenkov, V. V. Moroz

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Trends in the Management and Outcomes of Kidney Transplantation for Autosomal Dominant Polycystic Kidney Disease by Madhukar S. Patel, Praveen Kandula, David Wojciechowski, James F. Markmann, Parsia A. Vagefi

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Upper limb motor recovery in chronic stroke—longitudinal aggregate analysis from control group outcomes by Fabien Scalzo, Robert A. Coker, Lauren Souders, Leo Petrossian, Kern Bhugra, Lauren Sheehan, Eric C. Leuthardt, Eric C. Leuthardt, Alexander R. Carter

“…IntroductionThis study examines the effects of regular physical activity on upper extremity motor recovery during the late subacute and chronic phases of stroke.MethodsData were aggregated from 20 studies comprising 368 participants in control groups receiving usual care or general rehabilitation without specialized interventions. …”
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ERAS protocol in colorectal surgery is effective in octogenarians: A retrospective cohort study by Justin Dourado, MD, Ariel Wolf, MD, Maria Herrera Rodriguez, DO, Shruti Agarwal, BS, Karin Blumofe, MD, Jordan Moseson, DO, Jose Yeguez, MD, Andrew Ross, MD, Avraham Belizon, MD

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Sarcopenia and nutritional support for elderly and senile patients by T. N. Novikova, I. N. Pasechnik, V. Yu. Rybintsev

“…It is known that, in general, the duration of stay in intensive care units for elderly patients is much longer, and the results of treatment and rehabilitation are significantly lower than that of younger patients. …”
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The progress of the microbe-gut-brain axis in sepsis-associated encephalopathy by Chen He, Chen He, Hui Shi, Zhijie Yu, Chunhan Ma, Zhiqiang Jiao, Jin Li, Fei Yang, Fei Yang

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Depression of lncRNA NEAT1 Antagonizes LPS-Evoked Acute Injury and Inflammatory Response in Alveolar Epithelial Cells via HMGB1-RAGE Signaling by Hongchao Zhou, Xinhui Wang, Bin Zhang

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