The lived experience of withdrawal from Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants: A qualitative interview study by Raqeeb Mahmood, Vuokko Wallace, Professor Nicola Wiles, Professor David Kessler, Katherine S. Button, Graeme Fairchild

Get full text

Risk Factors for Acute Exacerbation in Patients with COPD Group E in Ningbo: Risk Analysis of Irregular Review, Cardiovascular Complications, and Lung Function Decline by Qian Y, Sun C, Zhang L, Cai C, Sun M, Zhang J, Huang J, Ma H, Tan L, Zhao Y, Wang S, Lv D

“…Yang Qian,1 Chao Sun,1 Liang Zhang,2 Chenting Cai,1 Mengqing Sun,1 Jiaqian Zhang,1 Jian Huang,3 Hongying Ma,1 Lin Tan,1 Yun Zhao,1 Shanshan Wang,1 Dan Lv1 1The First Affiliated Hospital of Ningbo University, Ningbo, 315010, People’s Republic of China; 2Ningbo Municipal Center for Disease Control and Prevention, Ningbo, 315000, People’s Republic of China; 3School of Big Data and Software Engineering, Zhejiang Wanli University, Ningbo, 315100, People’s Republic of ChinaCorrespondence: Dan Lv, The First Affiliated Hospital of Ningbo University, 59 Liuting Street, Ningbo City, Zhejiang Province, People’s Republic of China, Email fylvdan@nbu.edu.cnObjective: To understand the high-risk factors for disease progression in patients in the chronic obstructive pulmonary disease (COPD) group E in Ningbo, and to explore the impact of and treatment on the prognosis of these patients.Methods: We retrospectively analyzed the clinical data of 101 COPD patients in terms of general demographics, physical baseline data, lung function, disease treatment, and prognosis and used crosstab analysis and logistic regression analysis to understand the characteristics of the population of patients at high risk of acute exacerbation of COPD (AECOPD) and the associated risk factors.Results: Univariate analysis demonstrated that frequent acute exacerbation (AE) in the COPD group E population was significantly associated with more severe airflow limitation, a lower FEF75%, higher mMRC scores, and irregular disease management (P< 0.05). …”
Get full text

Myths and facts about functional neurological disorders: a cross-sectional study of knowledge and awareness among medical students and healthcare professionals in Iraq by Ahmed Hashim, Essam M Al-Sibahee, Sajjad Al-Badri, Nabeel Al-Fatlawi

“…Background Functional neurological disorder (FND) is a complex condition with neurological symptoms but no clear structural or biochemical explanation. …”
Get full text

Standardized evaluation of hand‐off documentation of ICU boarders in the emergency department by Joshua Kolikof, Daniel Shaw, Bryan Stenson, Anne Grossestreuer, Leon Sanchez, David Chiu

“…Our secondary outcome included variability in written quality as a function of the number of separate and distinct ED teams at the point of the transition of care. …”
Get full text

Investigating the feasibility and acceptability of the HOLOBalance system compared with standard care in older adults at risk for falls: study protocol for an assessor blinded pilo... by Matthew Liston, Christoph Maurer, Doris-Eva Bamiou, Dimitris Kikidis, Gregory Genna, Dimitris Gatsios, Dimitris Fotiadis, Marousa Pavlou

Get full text

The impact of war-related traumatic events on the functional psycho-emotional state of student youth in a front-line city: preliminary findings of the study by T.V. Peresypkina, V.G. Nesterenko, K.G. Pomohaibo, T.V. Merkulova

“…Also, the anonymous questionnaire included questions from the «W-A-M» – (well-being, activity, mood) test to assess the main components of the functional psycho-emotional state. Results. An anonymous study conducted among young students showed that among the consequences, a significant place is occupied by a decline in health, the acquisition of health-destructive habits by young people, a decrease in academic performance, limited access to medical and psychological care, and a significant level of migration, which even after a year and a half causes a level of maladjustment and stress. …”
Get full text

Prospective randomized, placebo-controlled study: role of branched-chain amino acids infusion as adjunct therapy post-liver surgery for patients in the intensive care unit by Eman Ibrahim El-Desoki Mahmoud, Faten Farid Awdallah

Get full text

Patient satisfaction with health status in rheumatoid arthritis based on remote assessment: a pilot OPTIMA study (Patient-reported Outcomes, Severity and Medical care in Arthritis) by E. Yu. Polishchuk, A. E. Karateev, H. R. Makhmudov, K. S. Kalashnikov, N. A. Bulgakova, A. M. Lila

Get full text

WCN25-1022 LONG-TERM KIDNEY FUNCTION BEYOND 12 MONTHS AND KIDNEY RELAPSE AFTER INITIATION OF TREATMENT FOR ANCA-ASSOCIATED VASCULITIS by Lisa Uchida, Vanja Ivkovic, Anna Matyjek, Duvuru Geetha, Balazs Odler, Carmel Hawley, Zachary S. Wallace, Carol McAlear, Mats Junek, Peter A. Merkel, Michael Walsh, David R.W. Jayne, Andreas Kronbichler

Get full text

Data linkage of German statutory health insurance claims data and care needs assessments preceding a population-based cohort study on nursing home admission by Karin Wolf-Ostermann, Dominik Domhoff, Kathrin Seibert, Susanne Stiefler, Dirk Peschke

“…The resulting dataset contains relevant information from both health services provision and functional status of care dependent people and is suitable for further analyses with critical reflection of representativity.…”
Get full text

Federated data health networks hold potential for accelerating emergency research by Prashant Mahajan, Charles Macias, Amie Barda, Christopher M. Fung

“…Abstract Multi‐center research networks often supported by centralized data centers are integral in generating high‐quality evidence needed to address the gaps in emergency care. …”
Get full text

Analysis of Drug and Health Resource Use Before and After COVID-19 Lockdown in a Population Undergoing Treatment for Depression or Anxiety by Ana Lear-Claveras, Ana Clavería, Ana Clavería, Ana Clavería, Sabela Couso-Viana, Sabela Couso-Viana, Patrice Nabbe, Bárbara Oliván-Blázquez, Bárbara Oliván-Blázquez, Bárbara Oliván-Blázquez

Get full text

Ovarian tissue cryopreservation for a girl with combined severe hemolytic anemia due to pyruvate kinase deficiency: a case report and literature review by Lingling Jiang, Xiangyan Ruan, Juan Du, Jiaojiao Cheng, Yanglu Li, Muqing Gu, Yanqiu Li, Fengyu Jin, Jinshan Zhang, Jianji Xu, Alfred O. Mueck

Get full text

Functional Outcome of Percutaneous K-wiring vs Closed Reduction and Plaster Casting in Treatment of Unstable Distal Radius Fractures: A Comparative Study by R Sahaya Jose, M Syed Moosa, N Kattu Bava

“…However, patients treated with K-wire fixation generally exhibited better functional outcomes, as indicated by lower DASH scores, improved range of motion, and fewer complications such as stiffness and moderate pain. …”
Get full text

Study protocol of the BLANKET trial: a cluster randomised controlled trial on the (cost-) effectiveness of a primary care intervention for fear of cancer recurrence in cancer survi... by Niek J de Wit, Charles W Helsper, Yvonne L Luigjes-Huizer, Marije L van der Lee

“…Therefore, there could be a role for general practitioners (GPs) and mental health workers (MHWs) working in primary care in supporting patients with FCR. …”
Get full text

Predictive Validity of Hospital-Associated Complications of Older People Identified Using Diagnosis Procedure Combination Data From an Acute Care Hospital in Japan: Observational S... by Seigo Mitsutake, Tatsuro Ishizaki, Shohei Yano, Takumi Hirata, Kae Ito, Ko Furuta, Yoshitomo Shimazaki, Hideki Ito, Alison Mudge, Kenji Toba

“… BackgroundA composite outcome of hospital-associated complications of older people (HAC-OP; comprising functional decline, delirium, incontinence, falls, and pressure injuries) has been proposed as an outcome measure reflecting quality of acute hospital care. …”
Get full text

Impact of a pharmacy-led screening and intervention in people at risk of or living with chronic kidney disease in a primary care setting: a cluster randomised trial protocol by Natasa Gisev, Sanjyot Vagholkar, Kamal Sud, Judy Mullan, Ines Krass, Anh Tran, Rita McMorrow, Wubshet Tesfaye, David W. Johnson, Connie Van, Vincent L. Versace, Judith Fethney, Breonny Robson, Lukas Kairaitis, Mariam Fathima, Vivien Tong, Natali Coric, Ronald L. Castelino

“…The trial consists of two arms: (1) Control Group: a risk assessment using the QKidney CKD risk assessment tool, and (2) Intervention Group: a risk assessment using the QKidney CKD plus Point-of-Care Testing for kidney function markers (serum creatinine and estimated glomerular filtration rate), followed by a QUM service. …”
Get full text

What factors are associated with informal carers’ psychological morbidity during end-of-life home care? A systematic review and thematic synthesis of observational quantitative stu... by Tracey Shield, Kerin Bayliss, Alexander Hodkinson, Maria Panagioti, Alison Wearden, Jackie Flynn, Christine Rowland, Penny Bee, Morag Farquhar, Danielle Harris, Gunn Grande

“…Impact of caring responsibilities (14 studies): impact on carers’ lives, task difficulty and general burden had clear associations with worse carer mental health. …”
Get full text

GLIMPSE: An Ultrafaint ≃105 M⊙ Pop III Galaxy Candidate and First Constraints on the Pop III UV Luminosity Function at z ≃ 6–7 by Seiji Fujimoto, Rohan P. Naidu, John Chisholm, Hakim Atek, Ryan Endsley, Vasily Kokorev, Lukas J. Furtak, Richard Pan, Boyuan Liu, Volker Bromm, Alessandra Venditti, Eli Visbal, Richard Sarmento, Andrea Weibel, Pascal A. Oesch, Gabriel Brammer, Daniel Schaerer, Angela Adamo, Danielle A. Berg, Rachel Bezanson, Rychard Bouwens, Iryna Chemerynska, Adélaïde Claeyssens, Miroslava Dessauges-Zavadsky, Anna Frebel, Damien Korber, Ivo Labbe, Rui Marques-Chaves, Jorryt Matthee, Kristen B. W. McQuinn, Julian B. Muñoz, Priyamvada Natarajan, Alberto Saldana-Lopez, Katherine A. Suess, Marta Volonteri, Adi Zitrin

“…Detecting the first generation of stars, Population III (Pop III), has been a long-standing goal in astrophysics, yet they remain elusive even in the JWST era. …”
Get full text

Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis by Jing Chen, Ning Pan, Li-Xin Wang, Xiaohe Zhou, Chengdong Wu, Xuru Wang, Xiaotong Sun, Bohao Chen, Shiya Zheng, Yiting Wei, Yuyang Wu, Fengjiao Zhu, Jinpeng Chen, Huabiao Chen

Get full text