CCL21-DC in situ vaccination in murine NSCLC overcomes resistance to immunotherapy and generates systemic tumor-specific immunity by Bin Liu, Rui Li, Edward B Garon, Steven M Dubinett, Kostyantyn Krysan, Tianhao Zhang, Aaron E Lisberg, Ramin Salehi-Rad, Raymond J Lim, Yushen Du, Linh M Tran, Stephanie L Ong, Zi Ling Huang, Camelia Dumitras, Stacy J Park, William Crosson, Bitta Kahangi, Jensen Abascal, Christopher Seet, Michael Oh, Maryam Shabihkhani, Manash Paul

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Randomized adaptive assessment of post COVID syndrome treatments (RAPID): a study protocol for a multicenter, randomized, controlled adaptive platform trial of treatment options fo... by Lisa Weipert, Ralph G. Telgmann, Gabriele Anton, Thomas Asendorf, Irina Chaplinskaja-Sobol, Sandra Ciesek, Oliver A. Cornely, Sonja Drescher, Carsten Finke, Tim Friede, Julia Groth, Sabine Hanß, Wolfgang Hoffmann, Cynthia Huber, Thomas Illig, Monika Kraus, Dagmar Krefting, Sebastian Kuhn, Andreas Muehler, Matthias Nauck, Jens Schaller, Ann-Cathrin Schmidt, Georg Schmidt, Birgit Sawitzki, Ralf Tostmann, Heike Valentin, Maria Vehreschild

“…Secondary endpoints include mental and physical health, intensity of fatigue, severity of mental disorder symptoms, and cognitive function. Discussion PCS is a major problem for global health care and the identification of treatment options is urgently needed. …”
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Cognitive disorders in patients with arterial hypertension in real medical practice. by T. A. Khomazyuk, V. Yu. Krotova, O. V. Sova, V. M. Yagolnik

“…Analysis of medical records testifies to the absence of attention to this issue in rehabilitation programs of hypertensive patients at the primary stage of care. The importance of timely diagnosis of cognitive disorders as a marker of early disorders of cerebral circulation and the functional state of the brain, the target organ in hypertension of 1-2 degrees was demonstrated.…”
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Cognitive disorders in patients with arterial hypertension in real medical practice by Khomazyuk T.A., Krotova V.Yu., Sova O.V., Yagolnik V.M.

“…Analysis of medical records testifies to the absence of attention to this issue in rehabilitation programs of hypertensive patients at the primary stage of care. The importance of timely diagnosis of cognitive disorders as a marker of early disorders of cerebral circulation and the functional state of the brain, the target organ in hypertension of 1-2 degrees was demonstrated.…”
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Successful Management Strategies for Lupus Nephritis in the Intensive Care Unit: A Case Series by Achmad Marwan, Bambang Pujo Semedi, Maulydia Maulydia

“…Patients with SLE undergoing immunosuppressive therapy are also at risk of developing infections, which can progress to sepsis and require more intensive care. Treatment of lupus nephritis in ICU generally necessitates intensive care, which includes hemodialysis and sepsis control. …”
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A Review of the Management, Outcomes, and Barriers to Rehabilitation in Patients With Post-intensive Care Syndrome by Arnengsih Nazir, Lynna Lidyana, Shofiyyah Sayyidah

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Diaphragmatic ultrasound-derived MV×DE: a novel predictor of postextubation adverse respiratory events in general anesthesia patients (observational study) by Jing Huang, Yanzi Yi, Xiaotian Zhang, XiaoXiao Li, Zhouquan Wu

“…Abstract Objective This study explored the potential of diaphragmatic ultrasonography in the postanaesthesia care unit (PACU) for predicting postextubation adverse respiratory events (PAREs) in patients recovering from general anaesthesia.--. …”
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Multiscale investigation of collagen structure in human skin and gel matrices using polarization resolved second harmonic generation microscopy by Mengyao Zhou, Madalena Pinto Gomes, Anouk Elgersma, H. Ibrahim Korkmaz, Bouke K. H. L. Boekema, Marie Louise Groot

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Managing Clopidogrel Resistance in Neurointervention: Surveying Current Approaches by Hyun Woo Kim, Ivo Bach, Juan Carlos Martinez Gutierrez, Adam A. Dmytriw, Salvatore D'Amato, Hussein A. Zeineddine, Albert J. Yoo, Sunil A. Sheth

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Early integration of palliative care in cervical cancer: Experiences from a pilot study by Treshita Dey, Anindya Mukerjee, Bhavana Rai, Minni Arora, Divyesh Kumar, GY Srinivasa, Sushmita Ghoshal

“…QoL was assessed by functional assessment of cancer therapy – general (FACT-G) questionnaire twice in both arms. …”
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Optimising laboratory monitoring of chronic conditions in primary care: a quality improvement framework by Alex J Walker, Richard Croker, Jessica Watson, Andy Brogan, Darunee Whiting, Tom Lewis

“…The main difference from previous general practitioner practice algorithms was removing the requirement for full blood count and liver function test monitoring for many conditions. …”
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Management and Outcomes in Confirmed or Suspected Acute Symptomatic Seizure: Role of Structured Outpatient Care by Vineet Punia, MarieElena Byrnes, Nicolas R. Thompson, Neishay Ayub, Clio Rubinos, Sahar Zafar, Adithya Sivaraju, Zhong Ying, Jessica R. Fesler, Stephen Hantus, Post‐Acute Symptomatic Seizure Investigation and Outcomes Network (PASSION) investigators

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Pre-infection liver function is associated with all-cause mortality among hemodialysis patients with SARS-CoV-2 Omicron variant infection by Quanchao Zhang, Caibao Lu, Han Wang, Shaofa Wu, Lili Jiang, Jie Li, Zhifen Wu, Bingshuang Tang, Bingfeng Yang, Shengli Liao, Liao Wang, Hongwei Chen, Moqi Li, Wenchang He, Yiqin Wang, Jin He, Jinghong Zhao, Ling Nie

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Environmental Levels and Degradation Behavior of Pharmaceuticals and Personal Care Products (PPCPs) in the Water Environment by Zhaohe ZHANG, Dian CHEN, Wei ZHAO, Guoli YUAN, Jun LI, Xingchun JIAO

“…Pharmaceuticals and personal care products (PPCPs) are a class of chemicals used by humans for daily life. …”
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Barriers and facilitators to optimal sepsis care – a systematized review of healthcare professionals’ perspectives by Lea Draeger, Carolin Fleischmann-Struzek, Sabine Gehrke-Beck, Christoph Heintze, Daniel O. Thomas-Rueddel, Konrad Schmidt

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Adaptation and pilot implementation of a hereditary cancer risk-assessment tool for primary care by Sukh Makhnoon, Anoop Gurram, Eyad Alrabbat, Tiwatope Ibidapo, Ying Ma, Emanuel Villa, Michael E. Bowen, Sayoni Lahiri, Celette Sugg Skinner, Sara Pirzadeh-Miller, Steven Leach

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Obesity and risk of death or dialysis in younger and older patients on specialized pre-dialysis care. by Ellen K Hoogeveen, Kenneth J Rothman, Pauline W M Voskamp, Renée de Mutsert, Nynke Halbesma, Friedo W Dekker, PREPARE-2 Study Group

“…<h4>Background</h4>Obesity is associated with increased mortality and accelerated decline in kidney function in the general population. Little is known about the effect of obesity in younger and older pre-dialysis patients. …”
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Evaluating the effectiveness of the national elderly care program in Oman: A cross-sectional study by Idris Aal Jumaa, Mohammed Al Ghafri, Nahid Bait Jamil, Jokha Al Sa'idi, Sitwat Usman Langrial, Salah Al Awaidy

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Morphology and Function of Myocardium and Skin Microcirculation 24 Hours after Clozapine Poisoning by I. A. Ryzhkov, A. S. Babkina, Z. I. Tsokolaeva, S. N. Kalabushev, V. V. Antonova, M. V. Sergeeva, A. V. Ershov

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Effect of remifentanil general anesthesia combined with thoracic paravertebral nerve block on the prognosis of elderly patients undergoing retroperitoneal laparoscopic radical neph... by LIU Haozhong, GAO Jinghao, QI Xiaomei, MA Wenru, XU Hao, WANG Pei, WANG Peng

“…Conclusion In elderly patients undergoing retroperitoneal laparoscopic radical nephrectomy, compared with remifentanil general anesthesia alone, its combination with TPVB can enhance postoperative analgesic effect and improve the quality of early postoperative recovery, with little impact on postoperative cognitive function, and it has no obvious adverse reactions.…”
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