Autoimmune hepatitis developed after acute liver failure due to hepatitis A. A case-report by Reina S. Velez-Ramirez, Yenni Joseline Cruz-Ramirez, Francisco I. Garcia-Juarez

“…The diagnosis of hepatitis A and acute liver failure was made.The patient suffers rapid clinical and biochemical deterioration, with multiple organ failure requiring admission to an intensive care unit and advanced life management area due to acute respiratory failure syndrome, general support stockings and three sessions of single-step albumin dialysis were indicated. …”
Get full text

OPTIMIZATION OF IMID-BASED THERAPIES by Murat Çınarsoy

“…In this case, it is clear that multiple myeloma treatment optimization cannot be achieved by considering multiple myeloma treatment only as applying the appropriate drug combination.In order to ensure the optimization of IMID-based therapies, it is necessary to take a broad perspective.This perspective should include the correct selection of the patient to be treated with IMID, the development and implementation of IMID forms that will increase patient compliance, the use of techniques to predict the development of resistance, side effect management during treatment, preventing the increase in disease burden with appropriate maneuvers by following the disease burden after treatment, and drug-free follow-up.It is recommended to avoid thalidomide in the presence of peripheral neuropathy, to prefer other agents instead of lenalidomide in the presence of renal function loss, and to avoid pomalidomide in patients with COPD.Nex-20, a once-monthly subcutaneous formulation of lenalidomide, is expected to be an important breakthrough in improving patient compliance.Prediction of which patients will develop resistance will be very useful in order to have the best treatment outcomes.Calculation of miRNA risk scores, measurement of lenalidomide metabolite levels in urine, measurement of cereblon levels in blood, or immunohistochemical detection of cereblon levels are some of the methods currently being tried to predict disease resistance.Patients who develop anemia should be treated with erythropoietin, skin reactions should be treated with steroids and antihistamines, diarrhea should be treated with loperamide and colestyramine, and in general, the drug should be discontinued and the same dose or a lower dose should be insisted upon.An important part of treatment is maintenance therapy with lenalidomide. …”
Get full text

Oral Health Differences Between Middle-Aged and Older Adults in South Korea by Yoonjung Ji, Wonhee Baek

“…The number of teeth exhibited the most positive association with oral health in both middle-aged (P < .001, β = 0.20, GDI = 5.30) and older (P < .001, β = 0.23, GDI = 7.40) adults. However, cognitive function, dental visits, body mass index, severe pain, functional limitations, and cognitive function exhibited distinct patterns between the age groups. …”
Get full text

Genetics and Traumatic Brain Injury: Findings from an Exome-Based Study of a 50-Patient Case Series by Alesya S. Gracheva, Darya A. Kashatnikova, Ivan V. Redkin, Vladislav E. Zakharchenko, Artem N. Kuzovlev, Lyubov E. Salnikova

Get full text

The main trends of dynamics of incomes of Russians in times of economic crisis by O. L. Petryakova

“…In article it is summarized that as a result of falling of the standard of living of a family begin to reduce consumption of paid services of education, health care that can lead to deterioration in performance of educational function and health protection of a family.…”
Get full text

The Impact of Anhedonia on the Disease Burden of Major Depressive Disorder in the Asia–Pacific Region: A Cross‐Sectional Real‐World Study by Keira Herr, Michael Berk, Wei‐Lieh Huang, Tadafumi Kato, Jung Goo Lee, Chong Guan Ng, Zhen Wang, Thomas Webb, Mami Kasahara‐Kiritani, Lawrence Vandervoort

“…Multivariate/generalized linear regression modeling (GLMs) and mediation analysis were used to assess anhedonia's impact on HRQoL/function, HRU, and work productivity. …”
Get full text

Ten-Year Outcomes after Acute STEMI Treated with Primary PCI – the Role of Acute Biomarkers and Other Parameters in Predicting Clinical Severity and Prognosis by Marko Mornar Jelavić, Zdravko Babić, Dorijan Babić, Diana Balenović, Ronald Lipovšćak, Hrvoje Pintarić

Get full text

T-Follicular Helper Cells and Their Role in Autoimmune Diseases by Michalis Christodoulou, Eleni Moysidou, Georgios Lioulios, Stamatia Stai, Christina Lazarou, Aliki Xochelli, Asimina Fylaktou, Maria Stangou

Get full text

Co-Design of a Health Screening Program Fact Sheet by People Experiencing Homelessness and ChatGPT: Focus Group Study by Nóra Radó, Orsolya Németh, Sándor Békási

“…Moreover, the involvement of generative AI technology revealed that the participants have heard about the concept of AI and text generation as a potential function, and they have not rejected its use in health care settings.…”
Get full text

Ethical considerations in prevention and management of non-communicable diseases: a narrative review by Elnaz Shahmohamadi, Aryan Ayati, Yasaman Sharifi, Pouya Ebrahimi, Ehsan Shamsi Gooshki, Shirin Djalalinia, Mahbube Ebrahimpur, Moloud Payab, Bagher Larijani

“…In addition to the practical aspects of implementing a response to NCDs, a variety of ethical considerations should be taken into account. For instance general policies, equity in care, interventional programs, and clinical/research data protection. …”
Get full text

Prevalence of Hypertension and Diabetes and Coexistence of Chronic Kidney Disease and Cardiovascular Risk in the Population of the Republic of Moldova by Igor Codreanu, Vera Sali, Sergiu Gaibu, Luminita Suveica, Sergiu Popa, Norberto Perico, Bogdan Ene-Iordache, Sergio Carminati, John Feehally, Giuseppe Remuzzi

“…Here we report data from the 2006-2007 screening program (1025 subjects from the general population) in the Republic of Moldova aimed to determine the prevalence of hypertension, diabetes, and their coexistence with microalbuminuria. …”
Get full text

Metastatic Adamantinoma of Fibula to the Lungs: A Rare Case Report by Knaj D, Ahmad G, Alshehabi Z, Ahmad IY

“…Two months later, she presented to the hospital in poor general condition. CT scan revealed extensive and progressive lesions in both lungs, leading to chest pain, hemoptysis, and hypoxia. …”
Get full text

Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease by Shulei Sun, Zhaoxiong Zhang, Haiyan Zhao

Get full text

Clinical Observation of Low-Temperature Plasma Knife Tonsil Adenoidectomy for Pediatric Snoring and Analysis of Influencing Factors by Li Guo, Yirong Hu

“…The children in group C were treated with power cutting system to remove adenoids combined with conventional peeling of bilateral tonsils, while the children in group O were treated with low-temperature plasma adenoidectomy combined with bilateral tonsillectomy, and both the groups received psychological care, preoperative preparation, health guidance, postoperative posture care and close monitoring of vital signs during the perioperative period. …”
Get full text

Oral Bacterial Lysate OM-85 Prevents Respiratory Tract Infections in Asthma: The OMRIA RWE Study by Christopoulou ME, Panteli LS, Moisidis JA, Christopoulos IA, Kasimeri ME, Tryphonidou AS, Christopoulos AI

“…Maria Elpida Christopoulou,1,2 Lilia S Panteli,1 John A Moisidis,1 Ioannis A Christopoulos,3 Maria Eleni Kasimeri,4 Amalia S Tryphonidou,1 Antonios I Christopoulos1,3 1Asthma Clinics, Primary Care Clinics for Asthma, Allergy &amp; Respiratory Health Athens, Patras, Kalavryta, Greece; 2Clinic of Pneumology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; 3Department of Respiratory Medicine, University General Hospital, Faculty of Medicine, University of Patras, Patras, Greece; 4Mid Yorkshire Teaching NHS Trust, Pinderfields Hospital, Wakefield, West Yorkshire, UKCorrespondence: Maria Elpida Christopoulou, Email maria.elpida.christopoulou@uniklinik-freiburg.de Antonios I Christopoulos, Email asthmaclinics@outlook.comBackground: OM-85 is a well-characterized bacterial lysate with antiviral properties, enhancement of airway epithelial barrier function, and tolerance induction. …”
Get full text

Cervical spinal cord injury following osteophyte excision for respiratory distress caused by diffuse idiopathic skeletal hyperostosis associated with ossification of posterior long... by Keisuke Masuda, Hideki Shigematsu, Akinori Okuda, Sachiko Kawasaki, Yusuke Yamamoto, Takahiro Mui, Yasuhito Tanaka

Get full text

The Specific Features of the Course of Critical Conditions in Miners by V. V. Moroz, Yu. A. Churlyaev, S. L. Kan

Get full text

The GluN3-containing NMDA receptors by Kunlong Xiong, Shulei Lou, Zuoyu Lian, Yunlin Wu, Zengwei Kou

Get full text

The correlations of serum uric acid with lean mass, fat mass and grip strength in adolescents aged 12-19 years by Feng Xu, Jianjun Shen, Zhongxin Zhu

Get full text