Increased Proportion of Dual-Positive Th2–Th17 Cells Promotes a More Severe Subtype of Asthma by Wenjin Sun, Yu Yuan, Lulu Qiu, Qingping Zeng, Jingsi Jia, Xudong Xiang, Aijun Jia, Libing Ma, Shaokun Liu, Bing Xiao

Get full text

Chronic constipation in Turkish children: clinical findings and applicability of classification criteria by Sema Aydoğdu, Murat Cakir, Hasan Ali Yüksekkaya, Ciğdem Arikan, Gökhan Tümgör, Maşallah Baran, Raşit Vural Yağci

“…Additionally, 1.8% of the children were not recognized by either Iowa or Rome criteria. Functional constipation is common in primary care, and most of the children were school-aged. …”
Get full text

Treatment Adherence and Its Associated Factors in Patients with Type 2 Diabetes: Results from the Rio de Janeiro Type 2 Diabetes Cohort Study by Fernanda S. Marinho, Camila B. M. Moram, Priscila C. Rodrigues, Nathalie C. Leite, Gil F. Salles, Claudia R. L. Cardoso

“…Patients with general good adherence had lower BMI, better serum lipid profile, higher values of functional capacity, emotional and pain domains of SF-36, better occupational performance, and lower prevalence of pain or limitation in the upper and lower limbs than patients with worse adherence. …”
Get full text

Recommendations of the Russian League Against Epilepsy (RLAE) on the use of magnetic resonance imaging in the diagnosis of epilepsy by G. N. Avakyan, D. V. Blinov, A. A. Alikhanov, E. M. Perepelova, V. A. Perepelov, S. G. Burd, A. V. Lebedeva, G. G. Avakyan

“…Implementation of these recommendations in clinical practice will improve the access to high-tech medical care and optimize health care costs.…”
Get full text

Autosexual behavior as a topic for inclusion in gynecological practice by Ewa Jakubek, Grażyna Jarząbek-Bielecka, Jacek Boroch, Małgorzata Mizgier, Katarzyna Plagens-Rotman, Witold Kędzia

“…In the Aristotelian sense, medicine is a habit of practical understanding, perfected by experience in patient care, and the issue of autosexual behavior in general gynecological requires special experience and an individual approach to a patient.…”
Get full text

The potential of large language models to advance precision oncology by Shufan Liang, Jiangjiang Zhang, Xingting Liu, Yinkui Huang, Jun Shao, Xiaohong Liu, Weimin Li, Guangyu Wang, Chengdi Wang

Get full text

Evaluation of respiratory muscle dysfunction in patients with idiopathic pulmonary fibrosis: a prospective observational study with magnetic resonance imaging by Xiaoyan Yang, Hongyi Wang, Anqi Liu, Yifei Ni, Jianping Wang, Yueyin Han, Bingbing Xie, Jing Geng, Yanhong Ren, Rongguo Zhang, Min Liu, Huaping Dai

Get full text

Practical Tips for Starting a Student-Run Free Eye Clinic [version 1; peer review: 1 approved, 2 approved with reservations] by Adam Leone, Robert Porter, Alec Murphy, Cameron Reinisch, Jonathan Regenold, Courtney Linne, Lisa Kelly, Hyun Jun Kim

“…Student-run free clinics serve three primary functions: 1) providing basic medical services for the uninsured and underserved in our communities, 2) supporting the training of medical providers, and 3) advocating for medically underserved communities. …”
Get full text

Dissecting spatio‐temporal protein networks driving human heart development and related disorders by Kasper Lage, Kjeld Møllgård, Steven Greenway, Hiroko Wakimoto, Joshua M Gorham, Christopher T Workman, Eske Bendsen, Niclas T Hansen, Olga Rigina, Francisco S Roque, Cornelia Wiese, Vincent M Christoffels, Amy E Roberts, Leslie B Smoot, William T Pu, Patricia K Donahoe, Niels Tommerup, Søren Brunak, Christine E Seidman, Jonathan G Seidman, Lars A Larsen

Get full text

Themis differentially regulates T follicular helper cell differentiation during early and late stages of chronic viral infection by Yuzhen Zhu, Yuzhou Bao, Ning Wang, Qifeng Gan, Jian Tang, Yu Cong, Bowen Hou, Bowen Hou, Minxue Quan, Chaonan Yan, Siyi Liu, Shuo Lin, Xiaobin Zhang, Yanping Du, Lichao Hou, Nicholas R. J. Gascoigne, Nicholas R. J. Gascoigne, Bing Xu, Guo Fu, Guo Fu, Guo Fu, Qifan Zheng

Get full text

Long-Term Benefits of N-Butylphthalide in Preventing Ischemic Stroke Recurrence: A 12-Month Prospective Study by Liu W, Shao Y, Liu J, Hao J, Lu Y, Yang L, Wang J, Ning X

“…Wei Liu,1,* Yingzhe Shao,1,* Jie Liu,2,* Juan Hao,1 Yuting Lu,3 Li Yang,1 Jinghua Wang,1,4,5 Xianjia Ning1,4,5 1Department of Neurology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China; 2Department of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, People’s Republic of China; 3School of Basic medical Sciences, Tianjin Medical University, Tianjin, 300070, People’s Republic of China; 4Laboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, 300052, People’s Republic of China; 5Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin, 300052, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xianjia Ning; Jinghua Wang, Department of Neurology, Tianjin Medical University General Hospital, Laboratory of Epidemiology, Tianjin Neurological Institute &Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, 154 Anshan Road, Heping District, Tianjin, 300052, People’s Republic of China, Tel +86-22-60817505 ; +86-22-60817504, Fax +86-22-60817448, Email xning@tmu.edu.cn; jwang3@tmu.edu.cnPurpose: This study evaluated the effects of 12 months of NBP treatment on stroke recurrence and examined the influence of age and gender on its efficacy.Methods: A prospective cohort of 1109 patients with non-cardioembolic ischemic stroke (IS) within six months was divided into NBP (n = 538) and control (n = 571) groups. …”
Get full text

Post-covid-19 conditions in adults: systematic review and meta-analysis of health outcomes in controlled studies by Christa Scheidt-Nave, Maria-Inti Metzendorf, Luis Ignacio Garegnani, Juan Victor Ariel Franco, Katharina Heldt, Rebekka Mumm

Get full text

The effect of abdominal massage applied after surgery on gastrointestinal symptoms and comfort level by Semiha Küçükaydınoğlu, Nuray Turan

“…Data were collected via the Patient Information Form, Functional Independence Measure (FIM), Bristol Stool Scale, Gastrointestinal Symptom Rating Scale (GSRS), and General Comfort Scale (GCS). …”
Get full text

Improving the Admission Department Performance under Reformation of the Secondary Medical Service Market by Oleh Skorba, Jean-Pierre Segers

“…They considered the development of the Ukrainian medical services market and determined the quality of medical care. This study examined the functioning of the admission department of the central district hospital. …”
Get full text

Comparative Analysis of Multidisciplinary Complementary Intervention Versus Routine Physiotherapy Rehabilitation to Reduce Kinesiophobia in Patients with Knee Osteoarthritis Underg... by Hung Tzu-Han, Liu Mei-Chun, Kuo Ya-Wen, Lee Jiann-Der

Get full text

The contribution of a short electrocardiographic diastolic interval to diastolic dysfunction and HFpEF by A. M. L. N. van Ommen, L. R. Bear, C. Carlos Sampedrano, N. C. Onland-Moret, M. J. Cramer, F. H. Rutten, E. Dal Canto, I. I. Tulevski, G. A. Somsen, N. K. Sweitzer, R. Coronel, H. M. den Ruijter

Get full text

Enhancing access to specialist appointments in tertiary healthcare in Shanghai, China: a structured reservation pathway using digital health technologies by Li Li, Tao Zheng, Enhong Dong, Minjie Chen, Xiaojing Zhao, Binyuan Zhang, Xuji Zhao, Weijun Shao, Yiling Fan

“…The outcome analysis employed a mixed-methods approach, integrating quantitative analysis with statistical and machine learning techniques, including multivariate logistic regression, random forest (RF) and artificial neural network (ANN) analysis.Setting This study was conducted at Renji Hospital, a premier general tertiary care institution in Shanghai, China, where the innovative PRP system was implemented. …”
Get full text

Gait Rehabilitation for Early rheumatoid Arthritis Trial (GREAT): lessons learnt from a mixed-methods feasibility study and internal pilot trial by Gordon J Hendry, Lindsay Bearne, Linda Fenocchi, Nadine E Foster, Sally Gates, Emma Godfrey, Samantha Hider, Lisa Jolly, Helen Mason, Alex McConnachie, Iain McInnes, Aimie Patience, Yeliz Prior, Catherine Sackley, Mandeep Sekhon, Bethany Stanley, Jason Vickers, Jim Woodburn, Martijn PM Steultjens

“…After finding the programme generally acceptable, we planned to compare it to usual care by randomly assigning participants to either the new intervention or their regular treatment. …”
Get full text

Innovations in Robot-Assisted Surgery for Genitourinary Cancers: Emerging Technologies and Clinical Applications by Stamatios Katsimperis, Lazaros Tzelves, Georgios Feretzakis, Themistoklis Bellos, Ioannis Tsikopoulos, Nikolaos Kostakopoulos, Andreas Skolarikos

“…This review also addresses the shift toward single-port systems and the rise of telesurgery enabled by 5G connectivity, highlighting global efforts to expand expert surgical care across geographic barriers. Collectively, these innovations represent a paradigm shift in robot-assisted urologic oncology, with the potential to enhance functional outcomes, surgical safety, and access to high-quality care.…”
Get full text

Genicular artery embolization for knee osteoarthritis: a systematic review with meta-analysis and cost-analysis by Aránzazu Hernández-Yumar, Yadira González-Hernández, Tasmania del Pino-Sedeño, Cristina Valcárcel-Nazco, Aythami de Armas-Castellano, Estefanía Herrera-Ramos, Julián Portero Navarro, Montserrat Carmona-Rodríguez, María Ximena Rojas-Reyes, María M. Trujillo-Martín

Get full text