Trial Conduct, Baseline Characteristics, and Symptom Burden of Patients in the ARISE Study by Charles L. Daley, James D. Chalmers, Patrick A. Flume, David E. Griffith, Naoki Hasegawa, Kozo Morimoto, Kevin L. Winthrop, Chau-Chyun Sheu, Korkut Avsar, Dario Andrisani, Luigi Ruffo Codecasa, Dayton W. Yuen, Mariam Hassan, Marie-Laure Nevoret, Kevin Mange

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Integrating Interpretability in Machine Learning and Deep Neural Networks: A Novel Approach to Feature Importance and Outlier Detection in COVID-19 Symptomatology and Vaccine Effic... by Shadi Jacob Khoury, Yazeed Zoabi, Mickey Scheinowitz, Noam Shomron

“…Studies have shown that individuals reporting sore throat may have a compromised immune system, where antibody generation is not functioning correctly. This aligns with our data, which indicates that 5% of patients with sore throats required hospitalization. …”
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To what extent is equity entrenched in HIV/AIDS-related policy documents in Ethiopia? A policy content analysis by Aklilu Endalamaw, Charles F. Gilks, Yibeltal Assefa

“…Health information systems should be designed in such a way that they generate and manage information to assess the extent of (in)equity and the progress towards equity in HIV/AIDS services.…”
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Chronic Abdominal Discomfort Syndrome (CADS): A Narrative Review of Treatment Strategies by Gupta M, Patil AS, Staats P, Schatman ME, Kalia H, Sayed D, Soin A, Baranidharan G, Kapural L, Chitneni A, Verrills P, Diwan S, Abd-Elsayed AA, Deer TR

“…Luke’s Rehabilitation Medical Center, Spokane, WA, USA; 3National Spine & Pain Centers, Frederick, MD, USA; 4Department of Anesthesiology, Perioperative Care & Pain Medicine, NYU Grossman School of Medicine, New York, NY, USA; 5Rochester Regional Health System, Rochester, NY, USA; 6The University of Kansas Health System, Kansas City, KS, USA; 7The Ohio Pain Clinic, Dayton, OH, USA; 8Leeds Teaching Hospitals NHS Trust, Leeds, UK; 9Carolinas Pain Institute, Winston-Salem, NC, USA; 10NewYork-Presbyterian, New York, NY, USA; 11Metro Pain Group, Clayton, VIC, Australia; 12Manhattan Spine & Pain, New York, NY, USA; 13University of Wisconsin-Madison, UW Health Pain Services, Madison, WI, USA; 14The Spine and Nerve Center of the Virginias, Charleston, WV, USA*These authors contributed equally to this workCorrespondence: Mayank Gupta, Email mayank.g@kansaspainmanagement.comAbstract: Chronic Abdominal Discomfort Syndrome (CADS) is a recently proposed term that is a subclassification of Chronic Abdominal Pain, characterized by symptoms affecting clinical, diagnostic, and functional domains. …”
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Use of ICT to Confront COVID-19 by Yousry Saber El Gamal

“…The risk of getting infected is a function of numerous factors where mathematical modeling would not yield fruitful results. …”
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Identification of nonsense variants in the genomes of 15 Murciano-Granadina bucks and analysis of their segregation in parent-offspring trios by Ke Wang, María Gracia Luigi-Sierra, Anna Castelló, Taina Figueiredo-Cardoso, Anna Mercadé, Amparo Martínez, Juan Vicente Delgado, Javier Fernández Álvarez, Antonia Noce, Mingjing Wang, Jordi Jordana, Marcel Amills

“…As a matter of fact, such a goal could only be achieved by generating a high-quality telomere-to-telomere goat reference genome combined with carefully curated annotation and functional testing of promising candidate variants.…”
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Inositol polyphosphate multikinase regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling by Chae Min Yuk, Sehoon Hong, Dongeon Kim, Mingyo Kim, Hyun-Woo Jeong, Seung Ju Park, Hyungyu Min, Wooseob Kim, Jongbu Lim, Hyo Dam Kim, Sang-Gyu Kim, Rho Hyun Seong, Seyun Kim, Seung-Hyo Lee

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Construction of mitochondrial signature (MS) for the prognosis of ovarian cancer by Miao Ao, You Wu, Kunyu Wang, Haixia Luo, Wei Mao, Anqi Zhao, Xiaomeng Su, Yan Song, Bin Li

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CFET Beyond 3 nm: SRAM Reliability Under Design-Time and Run-Time Variability by Sufia Shahin, Swati Deshwal, Anirban Kar, Mahdi Benkhelifa, Yogesh S. Chauhan, Hussam Amrouch

“…At the circuit level, a full array of 6T-static random access memory (SRAM) cells with the requisite peripheral circuits is simulated using SPICE after careful calibration of the industry-standard compact model of gate-all-around (BSIM-CMG) against the TCAD data. …”
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First trimester circulating miR-208b-3p and miR-26a-1-3p are relevant to the prediction of gestational hypertension by Andrée-Anne Clément, Cécilia LÉGARÉ, Véronique Desgagné, Kathrine Thibeault, Frédérique White, Michelle S. Scott, Pierre-Étienne Jacques, William D Fraser, Patrice Perron, Renée Guérin, Marie-France Hivert, Anne-Marie Côté, Luigi Bouchard

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Novel pathogenic mtDNA variants in Chinese children with neurological mitochondrial disorders by Zhimei Liu, Kexin Pan, Mingzhao Wang, Yijun Jin, Wenxin Yang, Keer Chen, Chaolong Xu, Xin Duan, Ying Zou, Changhong Ren, Lifang Dai, Suzhou Zhao, Ya Wang, Lijun Shen, Fang Fang, Hezhi Fang

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Enfermedad periodontal en embarazadas atendidas en la Clínica Estomatológica Manuel Angulo Farrán by Yunaydis Tamayo Avila

“…Conclusions: periodontal health is often affected in pregnancy, which is accentuated with the progress of pregnancy. Dental care is essential in early pregnancy to prevent functional damage that may be permanent psychological from the periodontal disease leading to tooth loss.     …”
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Integrating genome and transcriptome analysis to decipher balanced structural variants in unsolved cases of neurodevelopmental disorders by Simona Mellone, Alice Spano, Denise Vurchio, Giulia Borgonovi, Giulia Borgonovi, Alessandro Ugonotti, Giulia Paglino, Alba Bianco, Sara Ronzani, Maurizio Sciancalepore, Flavia Prodam, Flavia Prodam, Amanda Papa, Maurizio Viri, Umberto Dianzani, Umberto Dianzani, Mara Giordano, Mara Giordano

“…Transcriptomic analysis demonstrated the monoallelic and significantly reduced expression of EP300.ConclusionThese findings highlight the crucial role of WGS in identifying disease-associated BCAs and underscore the complementary value of RNA-Seq in assessing their functional consequences. This integrated approach enhanced diagnostic accuracy and clinical management, paving the way for more comprehensive and personalized care in these two patients.…”
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Suppression of the T-dependent antibody response following oral exposure to selected polycyclic aromatic compounds in B6C3F1/N mice by Victor J. Johnson, Cynthia V. Rider, Michael I. Luster, Cynthia J. Willson, Shawn Harris, Billie Stiffler, James Blake, Esra Mutlu, Veronica Godfrey, Brian Burback, Reshan Fernando, Suramya Waidyanatha, Gary R. Burleson, Dori R. Germolec

“…Additionally, there are several weaknesses in existing immunotoxicity databases for PACs in experimental animals, limiting their applicability in quantitative risk assessment. Careful characterization of strong positive and clear negative PACs is needed in order to lay the foundation for generating robust immunotoxicity data for structurally diverse PACs that have not yet been evaluated.MethodsIn the current study, adult B6C3F1/N female mice were treated daily for 28 consecutive days by oral administration of B(a)P to provide dose levels ranging between 2 and 150 mg/kg bodyweight/day. …”
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The PKC-β selective inhibitor, Enzastaurin, impairs memory in middle-aged rats. by Mari N Willeman, Sarah E Mennenga, Ashley L Siniard, Jason J Corneveaux, Matt De Both, Lauren T Hewitt, Candy W S Tsang, Jason Caselli, B Blair Braden, Heather A Bimonte-Nelson, Matthew J Huentelman

“…Protein Kinase C-β is an important enzyme for a variety of neuronal functions; in particular, previous rodent studies have reported deficits in spatial and fear-conditioned learning and memory with lower levels of Protein Kinase C-β. …”
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Resilience-by-Design in 6G Networks: Literature Review and Novel Enabling Concepts by Ladan Khaloopour, Yanpeng Su, Florian Raskob, Tobias Meuser, Roland Bless, Leon Janzen, Kamyar Abedi, Marko Andjelkovic, Hekma Chaari, Pousali Chakraborty, Michael Kreutzer, Matthias Hollick, Thorsten Strufe, Norman Franchi, Vahid Jamali

“…The sixth generation (6G) mobile communication networks are expected to intelligently integrate into various aspects of modern digital society, including smart cities, homes, health-care, transportation, and factories. …”
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Identification and validation of DNA methylation-driven gene OSR1 as a novel tumor suppressor for the diagnosis and prognosis of breast cancer by Jian Xu, Biao Yang, Ling Cheng, Chen Gan, Runze Huang, Anlong Li, Han Ge, Longyu Hu, Meiwen Ling, Xinyi Zheng, Bao Zhao, Mingjun Zhang, Huaidong Cheng, Huaidong Cheng

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Artificial intelligence in Anatomy: Potential uses and challenges by Lubna Faisal

“…Thus, AI benefits students in identifying not only primitive anatomical structures, relations, functions, and innervations but also unobserved anatomical structures [7]. …”
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Molecular mechanism of PANoptosis and programmed cell death in neurological diseases by Ketian Hou, Wenhan Pan, Lianhui Liu, Qianqian Yu, Jiahao Ou, Yueqi Li, Xi Yang, Zhenlang Lin, Jun Hui Yuan, Mingchu Fang

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Association between transcranial direct current stimulation and disability and quality of life in individuals with Parkinsonism: cross-sectional study by Ravi Shankar Reddy, Ravi Shankar Reddy, Jaya Shanker Tedla, Jaya Shanker Tedla, Irshad Ahmad, Venkata Nagaraj Kakaraparthi, Snehil Dixit, Kumar Gular, Paul Silvian Samuel, Suhail Mansour Aljehani, Feras Ahmed Alarabi

“…Transcranial direct current stimulation (tDCS) has shown promise in improving motor and cognitive functions when combined with physical therapy. This study aimed to explore the association between tDCS exposure and disability levels, as well as its impact on self-reported QoL in individuals with Parkinsonism undergoing physical therapy.MethodsThis cross-sectional study enrolled 51 participants diagnosed with Parkinsonism from a tertiary care hospital’s neurology outpatient clinic. …”
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