Prospective Cohort Study in Alport Syndrome Patients Under Standard Therapy by Oliver Gross, Michelle N. Rheault, James Simon, Bertrand Knebelmann, Yuqian Shen, Qi Zhang, Ali Hariri, Julie Lin, Shiguang Liu, Clifford E. Kashtan

“…Introduction: Patients with Alport syndrome (AS), a common genetic kidney disease, exhibit variable rates of decline in kidney function. Consequently, this global, multicenter, prospective observational study aimed to generate data useful for designing future interventional trials. …”
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Explanatory Model of Self-Efficacy for Cervical Cancer Screening by Angela-Cristina Yanez Corrales, Maria-Teresa Urrutia, Oslando Padilla

“…Methods: This study was conducted on 969 women aged 25–64 years who used the public health care system in Santiago, Chile. Multiple linear regression analysis was conducted to generate the explanatory model for global SE index and for each of their components as function of sociodemographic factors, factors related to interaction with the health system, risk factors for CC, family functioning, and the knowledge and beliefs of women regarding the disease and its prevention. …”
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Paternal microbiota manipulation influences offspring microbial colonization and development in a sex role-reversed pipefish by Kim-Sara Wagner, Frédéric Salasc, Silke-Mareike Marten, Olivia Roth

“…Vertical transmission is directly linked to reproductive success and entails early transmission, facilitating coexistence of host and microbes over generations. The multiple potentially interacting routes of vertical transmission are challenging to be disentangled in conventional sex-role species, as they are mostly intermingled on the maternal side, i.e., through egg production, pregnancy, birth and postnatal care. …”
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Neuro-Nutrition and Exercise Synergy: Exploring the Bioengineering of Cognitive Enhancement and Mental Health Optimization by Vicente Javier Clemente-Suárez, Alexandra Martín-Rodríguez, Agustín Curiel-Regueros, Alejandro Rubio-Zarapuz, José Francisco Tornero-Aguilera

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Near-Infrared Electronically-Controlled Variable Attenuator for W-Band Frequency Range by Suren Gigoyan, Mohammad-Reza Nezhad-Ahmadi

“…It is worth mentioning that the designed attenuator can also function as an mm-THz modulator. By carefully selecting a short carrier lifetime in doped silicon and choosing suitable LEDs, it is indeed possible to significantly increase the modulation rate.…”
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Protocol for Japan-acute retinal necrosis (J-ARN) registry: A combined prospective and retrospective cohort study. by Yoshihiko Usui, Reiko Kinouchi, Satoko Nakano, Chiharu Iwahashi, Keitaro Hase, Kenji Nagata, Masahiro Sugimoto, Eiichi Hasegawa, Kinya Tsubota, Sentaro Kusuhara, Masato Akiyama, Kenji Kashiwagi, Atsunobu Takeda, Toshikatsu Kaburaki, Hiroshi Goto, Koh-Hei Sonoda

“…A nationwide registry is needed to systematically collect data on ARN cases across Japan to improve understanding of this condition and optimize patient care. We have designed a national registry that collects data of patient characteristics, diagnosis, treatment, and visual outcome to generate evidence for the management of ARN.…”
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Fast and precise tongue pressure measurement by intraoral laser-induced graphene pressure sensor for elderly healthcare by Hyeonwoo Kim, Han Ku Nam, Tongmei Jing, Dongwook Yang, Younggeun Lee, Yong Kwon Chae, Seoung-Jin Hong, Sang Wook Kang, Young-Jin Kim

“…Tongue pressure (TP) monitoring is essential for evaluating oral functions and improving elderly healthcare, particularly in addressing challenges related to chewing, swallowing, and speech. …”
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Cold atmospheric plasma effectively kills chordoma cells through induction of intracellular reactive oxygen species by Sophie Peeters, Peter B. Wu, Blake Haist, Amber Armellini, Wi Jin Kim, Zhitong Chen, Richard Obenchain, George Ayad, Weihong Ge, Aparna Bhaduri, Graeme Sabiston, Robert M. Prins, Richard Wirz, Anthony C. Wang

“…Oftentimes, tumor infiltration into functionally critical, or difficult-to-access areas, precludes optimal resection. …”
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The Coaching for Cognition in Alzheimer's (COCOA) trial: Study design by Jared C. Roach, Junko Hara, Deborah Fridman, Jennifer C. Lovejoy, Kathleen Jade, Laura Heim, Rachel Romansik, Adrienne Swietlikowski, Sheree Phillips, Molly K. Rapozo, Maria A. Shay, Dan Fischer, Cory Funk, Lauren Dill, Michael Brant‐Zawadzki, Leroy Hood, William R. Shankle

“…Secondary outcome measures include the Functional Assessment Staging Test (FAST), a measure of function. …”
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235 Root cause analysis of barriers and facilitators to accrual to a pragmatic, EHR-embedded clinical trial by Lindsay Lennox, Bethany M Kwan, Adit A Ginde, Thomas W. Flaig, Sarah V Kautz, Matthew Mimnall, Andrew Nicklwsky, Goldie Komaie, Christine Velez, Aaron Babour, Laurie Blmberg-Romero, Cecilia C. Low Wang

“…We summarized data from the EHR by eligibility, provider encounters, and alerts, and generated CONSORT diagrams and tables to trace the enrollment pathway. …”
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THE ROLE OF PLATELET-RICH FIBRIN FACILITATES THE HEALING OF GASTROCNEMIUS MUSCLE DEFECT: A PRELIMINARY STUDY ON ANIMAL MODEL by Dwikora Novembri Utomo, Kukuh Dwiputra Hernugrahanto

“…Background: Scar formation has been a classical issue in the healing of skeletal muscle defect which will results in decrease of strength and function. Platelet-rich plasma (PRP) has been studied to enhance the healing of muscle defect. …”
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Policy Options for Contributory Health Insurance Schemes in Low and Lower-Middle Income Countries to Enable Progress Towards Universal Health Coverage by Agnes Gatome-Munyua, Joseph Kutzin, Cheryl Cashin

“…Instead, contributory health insurance has been found to exacerbate inequities in access to health care because entitlements are linked to contributions. …”
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Characterization of sucrose binding protein as a seed-specific promoter in transgenic tobacco Nicotiana tabacum L. by Nasibeh Chenarani, Abbasali Emamjomeh, Hassan Rahnama, Katayoun Zamani, Mahmoud Solouki

“…Moreover, the SBP promoter function in the seed oil content was evaluated by the expression of DGAT1. …”
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Assessing the Impact of Community-Based Rehabilitation on Pain Levels in Seniors – a Systematic Review by Anna Olech-Kuciemba, Agnieszka Wiśniowska-Szurlej

“…The analysed data indicate that rehabilitation based on exercises performed at home by seniors is effective, well-tolerated and generates lower health care costs.…”
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A low-cost printed circuit board-based centrifugal microfluidic platform for dielectrophoresis by Nicklas Rondot, Songyuan Yan, Dario Mager, Lawrence Kulinsky

“…The resulting DEPDisc platform solves the challenge that existing printed circuit board electrodes are reliant on expensive high-voltage function generators by boosting the voltage using resonant inductive power transfer. …”
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Metal oxides on the frontlines: Antimicrobial activity in plant-derived biometallic nanoparticles by Krishnan Anbarasu, Sathishkumar Kuppusamy, Devi Okram Ricky, Agrawal Smita, Debnath Abhijit, Arasu Mariadhas Valan, Sundaram Thanigaivel, Subramanian Kumaran, Karunakaran Rohini

“…One of the main themes involves antioxidant activity, as the biometallic nanoparticles made from plants have the natural capacity to scavenge free radicals, which enhances their antimicrobial effectiveness. The work carefully evaluates the processes behind this dual function, providing insight into the complex interactions between metal oxides and chemicals originating from plants. …”
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Large-scale genomic analysis reveals significant role of insertion sequences in antimicrobial resistance of Acinetobacter baumannii by Fei Xie, Lifeng Wang, Song Li, Long Hu, Yanhua Wen, Xuming Li, Kun Ye, Zhimei Duan, Qi Wang, Yuanlin Guan, Ye Zhang, Qiqi Shi, Jiyong Yang, Han Xia, Lixin Xie

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Advancing the Integration of Digital Health Technologies in the Drug Development Ecosystem by Sakshi Sardar, Cheryl D Coon, Scottie Kern, Huong Huynh, Diane Stephenson, Joshua Rubin Abrams, Grace V Lee, Cecile Ollivier, Joseph A Hedrick, Martijn LTM Müller, Luc J W Evers, Lada Leyens, Collin Hovinga, Shu Chin Ma, Klaus Romero

“…We propose the development of various standardized consensus frameworks to clearly lay out processes for various stakeholders and facilitate the seamless integration of the next generation of health care–sensing technologies into drug development.…”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
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A novel variant in the ALDH3A2 gene causative of Sjögren–Larsson syndrome evaluated in silico aids in proper genetic counseling and planning management by Ishwarya Chandrashekar Thirugnanam, Vigneshwaran Gurunadan, Srikanth Jilla, Sreelatha Komandur, Qurratulain Hasan

“…Management strategies focus on symptomatic relief through topical moisturizers and dietary modifications, emphasizing a multidisciplinary approach to patient care, especially in low-resource settings where gene therapy is not yet an option. …”
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