Next-Generation Biomaterials for Wound Healing: Development and Evaluation of Collagen Scaffolds Functionalized with a Heparan Sulfate Mimic and Fibroblast Growth Factor 2 by Merel Gansevoort, Sabine Wentholt, Gaia Li Vecchi, Marjolein de Vries, Elly M. M. Versteeg, Bouke K. H. L. Boekema, Agnes Choppin, Denis Barritault, Franck Chiappini, Toin H. van Kuppevelt, Willeke F. Daamen

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Exosome may be the next generation of promising cell-free vaccines by Zelan Dai, Ruiru Cai, Hong Zeng, Hailian Zhu, Youwei Dou, Shibo Sun

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Editorial: Empowering suicide prevention efforts with generative AI technology by Inbar Levkovich, Zohar Elyoseph, Sean Lauderdale, Gunther Meinlschmidt, Gunther Meinlschmidt, Bénédicte Nobile, Bénédicte Nobile, Dorit Hadar Shoval, Yossi Levi-Belz, Shiri Shinan-Altman, J. P. Grodniewicz

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Emberger Syndrome – A Family History Over 3 Generations by Laura Rüegsegger, Urs Schanz, Katja Seipel, Thomas Pabst, Jürg Schwegler, Elisabeth Schmidt, Adrian Schmidt

“…# Introduction Haploinsufficiency of _GATA2_ leads to impaired genesis and function of hematopoietic stem and progenitor cells, resulting in impairment of all subsequent blood cell lineages. …”
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E-cigarettes: An Emerging Threat to the Respiratory Health of Our Next Generation by Caitlin Hon Ning Yeung

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Next-generation carbon nanotube electrochemical sensors for liquid biopsy applications by Samuel Rantataro, Eero Gustafsson, Ilkka Varjos

“…Additionally, the SWCNT sensors are manufactured at mass manufacturing scale, making this platform suitable for point-of-care applications.…”
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Assessment of the Economic Efficiency of Long-Term Care System in the Stavropol Territory by I. I. Deren, K. A. Samofatova

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Next-Generation Cancer Treatment: Photoimmunotherapy’s Promise for Unresectable Head and Neck Cancers by Laura Marinela Ailioaie, Constantin Ailioaie, Gerhard Litscher

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Generation of Spatial Structure of Urban Parks Based on Spatial Analysis of Agent-Based Models by Huizi KONG, Tianming LIU, Jiajie LIAO, Liu CUI

“…The ABM simulation of slime mold growth behavior can effectively reflect the infiltration of surrounding functional information into the designed site, forming a spatial function zoning map with path texture. …”
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consHLA: a next generation sequencing consensus-based HLA typing workflow by Rachel Bowen-James, Weilin Wu, Marie Wong-Erasmus, Julian M. W. Quinn, Chelsea Mayoh, Mark J. Cowley

“…Abstract Background Human Leukocyte Antigens (HLA) play central roles in histocompatibility and immune system functions, including antigen presentation. Accurate typing of Class I and II HLA genes is crucial for transplant tissue matching, characterising autoimmune diseases and informing cancer immunotherapy. …”
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Summarizing Online Patient Conversations Using Generative Language Models: Experimental and Comparative Study by Rakhi Asokkumar Subjagouri Nair, Matthias Hartung, Philipp Heinisch, Janik Jaskolski, Cornelius Starke-Knäusel, Susana Veríssimo, David Maria Schmidt, Philipp Cimiano

“…ConclusionsTaken together, our results suggest that state-of-the-art pretrained language models are a valuable tool to provide qualitative insights about the patient experience to better understand unmet needs, patient priorities, and how a disease impacts daily functioning and quality of life to inform processes aimed at improving health care delivery and ensure that drug development focuses more on the actual priorities and unmet needs of patients. …”
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STAGER checklist: Standardized testing and assessment guidelines for evaluating generative artificial intelligence reliability by Jinghong Chen, Lingxuan Zhu, Weiming Mou, Anqi Lin, Dongqiang Zeng, Chang Qi, Zaoqu Liu, Aimin Jiang, Bufu Tang, Wenjie Shi, Ulf D. Kahlert, Jianguo Zhou, Shipeng Guo, Xiaofan Lu, Xu Sun, Trunghieu Ngo, Zhongji Pu, Baolei Jia, Che Ok Jeon, Yongbin He, Haiyang Wu, Shuqin Gu, Wisit Cheungpasitporn, Haojie Huang, Weipu Mao, Shixiang Wang, Xin Chen, Loïc Cabannes, Gerald Sng Gui Ren, Iain S. Whitaker, Stephen Ali, Quan Cheng, Kai Miao, Shuofeng Yuan, Peng Luo

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Generative AI for Industry 5.0: Analyzing the Impact of ChatGPT, DALLE, and Other Models by Siva Sai, Revant Sai, Vinay Chamola

“…The paper scrutinizes the multifaceted use-cases of GAI, emphasizing its instrumental function in amplifying operational efficiency, minimizing downtime, and fostering economic savings through predictive maintenance and acute real-time data analytics. …”
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T cell-specific non-viral DNA delivery and in vivo CAR-T generation using targeted lipid nanoparticles by Jacek Lubelski, Eline van Diest, Ator Ashoti, Christina Zotou, Hanneke Rijssemus, Raymond Schiffelers, Zhiyong Lei, Maurits Geerlings, Jaime Fernández Bimbo, Daniel E Murphy, Martijn J W Evers, Suneel A Narayanavari, Diana Pereira Vaz, Nadine Saber, Peter Mayrhofer

“…However, treatment accessibility is hindered by high costs, long manufacturing times, and the need for specialized centers and inpatient care. Strategies to generate CAR-T cells in vivo have emerged as a promising alternative that could bypass CAR-T manufacturing bottlenecks. …”
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Versatile Standing Wave Generation Between Arbitrarily Oriented Surfaces Using Acoustic Metasurface Deflectors and Retroreflectors by Chadi Ellouzi, Farhood Aghdasi, Ali Zabihi, Amir K. Miri, Chen Shen

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Arteriovenous cerebral high-flow shunts: genetic analysis of patients from a pediatric tertiary care center by Ferruccio Romano, Patrizia De Marco, Giulia Amico, Marisa Mallamaci, Marco Pavanello, Gianluca Piatelli, Marcello Scala, Federico Zara, Federico Zara, Federico Zara, Federico Zara, Federico Zara, Francesca Faravelli, Mariasavina Severino, Mariasavina Severino, Domenico Tortora, Domenico Tortora, Francesco Pasetti, Lucio Castellan, Silvia Buratti, Silvia Buratti, Silvia Buratti, Valeria Capra

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Improving the core functions of primary care in a Ugandan rural district by Innocent K. Besigye, Robert J. Mash

“…Community dialogues as form of community engagement were selected as an intervention to improve the core primary care functions. Conclusion: The PCAT can generate findings to guide the development of interventions at the facility and district level to potentially improve the core functions of primary care. …”
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The Evolving Role of Alkylating Agents in Multiple Myeloma: From the Past and Present to Next-Generation Peptide Drug Conjugates by Yuxin Liu, Shahrier Hossain, Omar Nadeem, Shonali Midha, Monique Hartley-Brown, Taya Salman, Pedro Vianna, Adam S. Sperling, Giada Bianchi, Clifton Mo, Jacob Laubach, Paul G. Richardson

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Multimodal Metaverse Healthcare: A Collaborative Representation and Adaptive Fusion Approach for Generative Artificial-Intelligence-Driven Diagnosis by Jianhui Lv, Adam Slowik, Shalli Rani, Byung-Gyu Kim, Chien-Ming Chen, Saru Kumari, Keqin Li, Xiaohong Lyu, Huamao Jiang

“…The metaverse enables immersive virtual healthcare environments, presenting opportunities for enhanced care delivery. A key challenge lies in effectively combining multimodal healthcare data and generative artificial intelligence abilities within metaverse-based healthcare applications, which is a problem that needs to be addressed. …”
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Current progress and remaining challenges of peptide–drug conjugates (PDCs): next generation of antibody-drug conjugates (ADCs)? by Dongyuan Wang, Feng Yin, Zigang Li, Yu Zhang, Chen Shi

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