Cardiovascular-kidney-metabolic syndrome definition and its role in the prevention, risk staging, and treatment. An opportunity for the Nephrology by Aleix Cases, Jose Jesus Broseta, Maria Marqués, Secundino Cigarrán, Juan Carlos Julián, Roberto Alcázar, Alberto Ortiz

“…Three publications offer the rational basis of a conceptual decalogue and action plan and a new cardiovascular risk stratification equation since the age of 30 that includes measures of renal function/damage, among others, to promote effective cardiovascular, renal, and metabolic prevention. …”
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The implications and requirements of transcatheter aortic valve replacement in low-risk patients by Emin Murat Tuzcu, Ahmad Edris

“…The use of TAVR in low-risk patients has important implications and requires a multifaceted approach that includes a highly functional multidisciplinary heart team for careful patient selection; a need to understand and help mitigate certain key complications, such as stroke, paravalvular regurgitation, and conduction disturbances; careful data collection for continual outcome assessment and improvement; and the necessary expertize and procedural volume to maintain excellent outcomes and ensure optimal clinical care pathways.…”
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Quantitative Relationships Between Basalt Geochemistry, Shear Wave Velocity, and Asthenospheric Temperature Beneath Western North America by M. Klöcking, N. J. White, J. Maclennan, D. McKenzie, J. G. Fitton

“…Forward and inverse modeling of carefully selected major, trace, and rare earth elements were used to determine melt fraction as a function of depth. …”
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Neoadjuvant chemotherapy in oral cancers: Selecting the right patients by S Vishak, Bharath Rangarajan, Vikram D Kekatpure

“…In a select subset of patients with locally very advanced and unresectable OSCC, neoadjuvant chemotherapy has been shown to cause tumor shrinkage and improve resectability. These hypothesis generating findings of reduction in distant metastasis, improved resectability and functional outcome, however need further validation. …”
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Autonomous and sustainable machine learning: pursuing new horizons of intelligent systems by Witold Pedrycz

“…Those manifest evidently when Machine Learning constructs have to function autonomously and any decisions being rendered entail far reaching implications. …”
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Validation of a Clinical Scale for Early Detection of Infections at the Exit Site of Central Venous Catheters for Hemodialysis by José Luis Cobo-Sánchez, Ian Blanco-Mavillard, Raquel Pelayo-Alonso, Noelia Mancebo-Salas, Ismael Fernández-Fernández, Irene Larrañeta-Inda, Ana Ulzurrun-García, Isidro Sánchez-Villar, Fernando González-García, Julia Hernando-García, Ma Jesús Rollán-de la Sota, Luís Miguel Vieira-Barbosa Lopes, Ma del Rosario Prieto-Rebollo, Carolina Sesmero-Ramos, Catalina Jaume-Riutort, Rafael Casas-Cuesta, Mateo Alcántara-Crespo, Joan Ernest de Pedro-Gómez

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Lifestyle factors and health outcomes associated with infertility in women: A case-control study using National Health Insurance Database by Boyoung Jeon, Taeuk Kang, Sung Wook Choi

“…Employing a case–control study design, lifestyle factors (drinking, smoking, and physical activity) and health checkup outcomes (underweight, overweight, hypertension, diabetes, kidney function, anemia, and menstrual disorders) were assessed in this study. …”
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Vascular Access for Home Hemodialysis: A Perspective on Tunneled Central Venous Catheters at Home by Michael Alexander Aragon, Osama El Shamy, Sijie Zheng, Glenn M. Chertow, Joel Glickman, Eric Weinhandl, Paul Komenda, Stephan Dunning, Frank Liu, Charmaine Lok

“…One such barrier is vascular access for HHD; although tunneled hemodialysis central venous catheters (CVCs) have been used for decades, physicians still hesitate to send patients home without a mature, functional arteriovenous access. An expert panel of clinicians was convened by Outset Medical, a manufacturer of hemodialysis systems, to review the literature and generate consensus recommendations regarding the use of CVCs for HHD. …”
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Silver(I)-induced anisotropy in the plasmon-driven growth of nanoscale gold by Asher L. Siegel, Arren J. Mallott, Devanshi N. Patel, Luis Polo-Parada, Gary A. Baker

“…The strategy also relies on L-pyroglutamic acid, a natural amino acid metabolite, as a photochemical relay aiding in the transport and localization of plasmon-generated hot electrons. By carefully adjusting reagent concentrations, the morphologies of the resulting nanoparticles can be facilely tuned from spheres to nanostars and nanoflowers. …”
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Systematic Review of Total Hip Arthroplasty Outcomes in Cerebral Palsy Patients and a Comparative Analysis with Rheumatoid Arthritis by Christos Costa, Foteini Moniati, Michalis Chatzimatthaiou, Christos Papaioannou, Sapfo Athanasakopoulou, Marios Chatzimatthaiou

“…The current literature suggests that THA is a beneficial procedure for patients with CP through pain reduction and functional improvement. However, the increased rates of potential complications compared to the general population require careful consideration. …”
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Designing A Blockchain-Empowered Telehealth Artifact for Decentralized Identity Management and Trustworthy Communication: Interdisciplinary Approach by Xueping Liang, Nabid Alam, Tahmina Sultana, Eranga Bandara, Sachin Shetty

“… BackgroundTelehealth played a critical role during the COVID-19 pandemic and continues to function as an essential component of health care. …”
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Association of the blood urea nitrogen to serum albumin ratio and all-cause mortality in critical ill acute ischemic stroke patients: a retrospective cohort study of MIMIC-IV datab... by Yongwei Huang, Zongping Li, Jianjun Wang, Jianjun Wang, Decai Wang, Decai Wang, Xiaoshuang Yin

“…PurposeWe aim to ascertain the extent to which the blood urea nitrogen (BUN) to serum albumin (ALB) ratio (BAR) could be implemented to anticipate the short- and long-term prognosis of acute ischemic stroke (AIS) patients in intensive care units (ICUs).MethodsThe data was derived from the Marketplace for Intensive Care Medical Information-IV (MIMIC-IV v3.0) database, primarily pertaining to AIS patients as categorized by the International Classification of Diseases (ICD)-9 and ICD-10. …”
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Multi-omics integration reveals Vha68-3 as a testicular aging-specific factor that coordinates spermatid elongation through mitochondrial metabolic homeostasis by Jun Yu, Qiuru Huang, Yangbo Fu, Lei He, Cong Shen, Xia Chen, Zhiran Li, Jiaxin Li, Chenyu Wang, Xinda Wang, Binbin Yang, Ziwen Lin, Chen Qiao, Xiaofang Tan, Xiaoqing Yang, Hao Chen, Ying Zheng, Bo Zheng, Fei Sun

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Development and validation of a machine-learning-based model for identification of genes associated with sepsis-associated acute kidney injury by Chen Lin, Meng Zheng, Wensi Wu, Zhishan Wang, Guofeng Lu, Shaodan Feng, Xinlan Zhang

“…Despite therapeutic options such as antibiotics and supportive care, early diagnosis and treatment remain a challenge. …”
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Combined metabolomic and transcriptomic analysis reveals the key genes for triterpenoid biosynthesis in Cyclocarya paliurus by Duo Chen, Xupeng Chen, Xuehai Zheng, Jinmao Zhu, Ting Xue

“…Abstract Background Cyclocarya paliurus is a high-value tree, and it contains a variety of bioactive secondary metabolites which have broad application prospects in medicine, food and health care. Triterpenoids can improve the bioactive function of C. paliurus health tea and also improve the efficacy of health care tea. …”
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Study protocol using informatics to identify and recruit a cohort of older adults in Florida to develop teleneuropsychological norms by Glenn Smith, Ambar Perez-Lao, Gelan Ying, Ellie Mitova, Amanda Morales, David Marra, Franchesca Arias, Shellie-Anne Levy

“…They will also complete questionnaires related to sociodemographic information, depression, functionality and social determinants of health. Participants will undergo a teleneuropsychological battery examination via remote assessment. …”
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Fixed Regimen Treatment in Unselected Naïve Patients Cohort with Neovascular Age-Related Macular Degeneration by Ricardo P. Casaroli-Marano, Carolina Bernal-Morales, Lillian Chamorro-López, Marina Dotti-Boada, Juan P. Figueroa-Vercellino, Socorro Alforja

“…The current treatment of neovascular age-related macular degeneration (nAMD) generates an excessive care pressure in the public health system. …”
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Stereotactic body radiotherapy: a new non-invasive way to conduct pulmonary artery denervation by Manzhen Liao, Manzhen Liao, Taoyue Yao, Yonghui Xie, Shelby Kutty, Jinqiao Liu, Wei Peng, Wei Peng, Ting Huang, Huaiyang Chen, Huaiyang Chen, Haoqin Fan, Zhenghui Xiao, Qiming Liu, Yunbin Xiao

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Deletion of Tfap2a in hepatocytes and macrophages promotes the progression of hepatocellular carcinoma by regulating SREBP1/FASN/ACC pathway and anti-inflammatory effect of IL10 by Zhiwei Li, Chun Zhang, Guixiang Huang, Zixin Zhang, Qinghao Wang, Xiran Liu, Yanling Qin, Hao Zhou, Anyi Hou, Jun He, Limin Li, Xiang Hu, Xiaofeng Ding

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A Digital Mental Health Solution to Improve Social, Emotional, and Learning Skills for Youth: Protocol for an Efficacy and Usability Study by Kayla V Taylor, Laurent Garchitorena, Carolina Scaramutti-Gladfelter, Mykayla Wyrick, Katherine B Grill, Azizi A Seixas

“…ConclusionsThe STEMSEL study plays a crucial role in assessing the feasibility and adoption of digital mental health interventions within the school-aged youth population in the United States. The findings generated from this study have the potential to dismantle obstacles to accessing mental health assistance and broaden the availability of care through evidence-based strategies. …”
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