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Integrable deformations of dimensionally reduced gravity
Published 2025-06-01“…The Auxiliary Field Deformation, in particular, preserves the rich algebraic structure underlying the undeformed model and, leaving the canonical structure of the Lax connection’s spatial components essentially unchanged, allows us to prove its integrability also in the Hamiltonian sense.…”
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42
A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis.
Published 2011-03-01“…Typically, the recruitment of a fluorescent protein-tagged endocytic protein was referenced to the disappearance of spot-like clathrin-coated structure (CCS), but the precision of spot-like CCS disappearance as a marker for canonical CME remained unknown. …”
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43
Bioinformatic Analysis of WNT Family Proteins
Published 2025-07-01“…Their diverse biological functions are mediated through multiple signaling pathways, including both canonical β-catenin-dependent and several non-canonical mechanisms. …”
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Molecular mechanism of Activin receptor inhibition by DLK1
Published 2025-07-01“…Here, we show that DLK1 does not bind to Notch receptors or affect ligand-mediated Notch activation, but instead engages the TGF-β superfamily member Activin receptor type 2B (ACVR2B). The crystal structure of the DLK1-ACVR2B complex reveals that DLK1 mimics the binding mode of canonical TGF-β ligands to compete for access to ACVR2B. …”
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Insulin resistance contribution to pathogenesis of cardiac remodeling in patients with hypertension in combination with obesity and type 2 diabetes
Published 2020-05-01“…We performed a clinical examination, assessed cardiac structure, insulin levels and insulin resistance indices. …”
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47
Investigating Natural Product Inhibitors of IKKα: Insights from Integrative In Silico and Experimental Validation
Published 2025-05-01“…The inhibitory κB kinases (IKKs), particularly IKKα, are central to modulating NF-κB activity, with distinct roles in the canonical and non-canonical signaling pathways. This study investigates the potential of selectively targeting IKKα to develop novel therapeutic strategies. …”
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48
Classical and quantum cosmology of f(R) gravity’s rainbow in Schutz’s formalism
Published 2025-06-01“…In the classical regime, we derive and solve the equations of motion, obtaining both analytical and numerical solutions. Through canonical quantisation, we formulate the Schrödinger–Wheeler–DeWitt (SWD) equation for the quantum model. …”
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49
Distinctive biochemical properties of the μ-opioid receptor-corticotropin- releasing factor CRF1 receptor heterotetramer
Published 2025-09-01“…Heteromerization of Gs with Gi protein-coupled receptors has been suggested to be necessary to sustain the canonical Gi-Gs antagonistic interaction at adenylyl cyclase (AC). …”
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50
Aux/IAAs: specificity and redundancy
Published 2025-12-01“…This review summarizes the structural features of Aux/IAA proteins, the functional diversity of non-canonical members, the phenotypic effects of their mutants, and their expression patterns. …”
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51
CYK4 promotes antiparallel microtubule bundling by optimizing MKLP1 neck conformation.
Published 2015-04-01“…Our work provides insights into the microtubule bundling during cytokinesis and into the working mechanisms of the kinesins with non-canonical neck structures.…”
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52
Inhibitory basal ganglia nuclei differentially innervate pedunculopontine nucleus subpopulations and evoke differential motor and valence behaviors
Published 2025-08-01“…The canonical basal ganglia model predicts that the substantia nigra pars reticulata (SNr) will inhibit locomotion and the globus pallidus externa (GPe) will enhance it. …”
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53
Mirtrons in Human Cancers
Published 2025-02-01“…What sets mirtrons apart from canonical miRNAs is their unique mode of biogenesis and structural attributes, which reveal alternative regulatory mechanisms that could be exploited in cancer biology. …”
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Resistance mutations impair benzimidazole efficacy against Ascaridia galli by altering β-tubulin interactions
Published 2025-08-01“…., F167Y, E198A, and F200Y) that occur in the β-tubulin genes of helminths thereby affecting the structure of the expressed protein. This research aims to determine the effects of these canonical resistance-associated mutations on the in silico binding of A. galli β-tubulin and benzimidazole drug ligands. …”
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Improvement of Calculation Technique for Flexible Orthotropic Plates on Elastic Base. Part 2. Calculation Results
Published 2022-08-01“…Zhemochkin. A mixed method of structural mechanics has been used to determine the coefficients of canonical equations and free terms. …”
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Enhanced conformal BMS3 symmetries
Published 2025-04-01“…It is shown to emerge from the asymptotic structure of an extension of conformal gravity in 3D by Pope and Townsend that consistently accommodates an additional spin-2 field, once it is endowed with a suitable set of boundary conditions. …”
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Neosemantization of Word NISHCHEBROD in Modern Russian Speech
Published 2019-11-01“…Special attention is paid to the development of semantic differentiation of canonical and actual for modern times meanings of the noun nishchebrod . …”
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Rephasing invariants of CP violation for heavy and light Majorana neutrinos
Published 2025-09-01“…In the canonical seesaw mechanism, the strengths of charged-current interactions for light and heavy Majorana neutrinos are described respectively by the 3×3 matrices U and R that are correlated with each other via the exact seesaw relation and the unitarity condition. …”
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59
On a lower-dimensional Killing vector origin of irreducible Killing tensors
Published 2025-07-01“…It gives rise to a tower of growing rank Killing tensors determined by the structure constants of the corresponding Lie algebra. …”
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SEMANTICS OF ARCHAIC IMAGERY IN NORTH CAUCASIAN LITERATURE
Published 2019-09-01“…This article is supposed to consider the symbolic forms of reproduction of the ethnic picture of the world through mythological consciousness, fixed ideas of a person about the structure of the habitual living space, mechanisms of self-identification of the ethnic group. …”
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