Precision medicine in rheumatoid arthritis: Evaluation of a new approach to predict clinical response to methotrexate in patients with early rheumatoid arthritis. by Alejandro Escudero, Mercedes Alperi, Ana Isabel Turrion, Rosario Lopez, Tatiana Yebra, Gema Cordero, Teresa Diez, Isabel Portero, Francisco J Blanco

“…Monocyte metabolic activity (Monocytes Test) and reactive oxygen species (ROS Test) in peripheral blood were measured in vitro before treatment, and response to MTX and remission was measured at 6 months. …”
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ACTOPROTECTIVE ACTIVITY OF THE COMPLEX PLANT REMEDY by B. A. Muruev, A. G. Mondodoev, I. E. Matkhanov, A. A. Toropova, L. N. Shantanova, O. G. Dimitrov, O. V. Yundunova, I. S. Butukhanova

“…The content of ATP, lactic acid and pyruvic acid were determined in the skeletal  muscle homogenate; glycogen was determined in the liver  homogenate; in the blood serum there was estimated concentration  of malonic dialdehyde, the activity of catalase; the concentration of  reduced glutathione was determined in the whole blood and the  activity of superoxide dismutase was estimated in erythrocytes.Conclusion. …”
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Sudden and Unexpected Seizure during Emergency Cesarean Section in a Nonhypertensive Hypothyroid Primigravida by J Kausik, D Divya, S Parthasarathy

“…The patient was given oxygen, 2 mg of intravenous midazolam, and magnesium sulfate by the Pritchard regimen. …”
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Effect of tocilizumab on pulmonary gas exchange function in patients with severe COVID-19 by D. A. Lebedev, Yu. Kh. Dolya, G. E. Savkov, M. A. Godkov, E. V. Klychnikova, А. P. Shakotko, D. A. Kosolapov, S. N. Kuznetsov, A. M. Kvasnikov, Yu. N. Vrabiy, K. V. Kiselev, V. B. Poluektova, S. S. Petrikov, K. A. Popugaev

“…The study included 26 patients in whom gas exchange parameters (PaO2, PaCO2, P/f ratio), blood oxygen saturation (saturation), respiration rate, duration and parameters of high-flow oxygen therapy and noninvasive mechanical ventilation, length of stay in intensive care unit and total hospital length of stay were assessed.Results. …”
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Cardiopulmonary factors associated with atrial fibrillation in patients with chronic obstructive pulmonary disease by E. I. Leonova, G. G. Shechyan, V. S. Zadionchenko, T. V. Adasheva, A. D. Deev, I. V. Fedorova

“…According to the results of multiple correlation analysis, the frequency of AF paroxysms correlated with forced expiratory volume in 1 sec (FEV1) (R=-0.348; p=0.013), minimum oxygen saturation of the blood (min%SpO2) (R=-0.356; p=0.011), CRP level (R=0.442; p=0.001), the sizes of both atria (p<0.001), isovolumic relaxation time (IVRT) of left ventricle (LV) (R=0.350; p=0.022), the right ventricle (RV) size (R=0.478; p<0.001), systolic blood pressure level in the pulmonary artery (PASP) (р<0.001), vascular stiffness - pulse wave velocity in aorta (PWao) (p=0.001). …”
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Cardiopulmonary factors associated with atrial fibrillation in patients with chronic obstructive pulmonary disease by E. I. Leonova, G. G. Shechyan, V. S. Zadionchenko, T. V. Adasheva, A. D. Deev, I. V. Fedorova

“…According to the results of multiple correlation analysis, the frequency of AF paroxysms correlated with forced expiratory volume in 1 sec (FEV1) (R=-0.348; p=0.013), minimum oxygen saturation of the blood (min%SpO2) (R=-0.356; p=0.011), CRP level (R=0.442; p=0.001), the sizes of both atria (p<0.001), isovolumic relaxation time (IVRT) of left ventricle (LV) (R=0.350; p=0.022), the right ventricle (RV) size (R=0.478; p<0.001), systolic blood pressure level in the pulmonary artery (PASP) (р<0.001), vascular stiffness - pulse wave velocity in aorta (PWao) (p=0.001). …”
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Transcriptomics reveals the underlying mechanism of Prostaglandin E1 in improving severe pneumonia by Wentong Ma, Jingxin Zhou, Ying Qian, Su Zhang, Chuanlu Han, Jing Su, Haijun Sun

“…Results PGE1 can alleviate lung histopathological injury in mice with severe pneumonia, decrease W/D ratio, attenuate interleukin- 1β (IL-1β), interleukin- 6 (IL-6), and tumor necrosis factor-α (TNF-α) levels, increase interleukin- 10 (IL-10) levels in mouse BALF and lung tissues, and reduce the number of WBCs and PMNs; it can increase the arterial blood partial pressure of oxygen (PaO2) and decrease the arterial blood partial pressure of carbon dioxide (PaCO2), and up-regulate the proportion of Treg cells, decrease RORγt expression, and increase Foxp3 expression. …”
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THE MODERN VIEW OF THE ADDITIONAL THERAPY, CORRECTING METABOLIC PARAMETERS IN PATIENTS WITH PULMONARY HYPERTENSION: TRIMETAZIDINE IN FOCUS by E. G. Valeeva, T. V. Martyniuk, K. P. Ivanov, V. B. Sergienko, S. N. Nakonechnikov, I. Ye. Chazova

“…Currently, the cause of this symptoms can be as coronary heart disease, compression of the coronary arteries (usually the left main coronary artery) dilated pulmonary artery, coronary insufficiency due to low cardiac output is relatively weak development of coronary collaterals in the hypertrophy RV wall or a reflex constriction of the coronary arteries due to distension of the pulmonary artery, to the reduction of blood oxygen saturation in the late stages of the disease. …”
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The utility of monitoring end-tidal carbon dioxide in emergency department to predict inhospital mortality of patients presenting with nontraumatic shock: A prospective observation... by R Abhiraj, Meera Ekka, Aravind Sreekumar, Praveen Aggarwal, Nayer Jamshed, Sanjeev Kumar Bhoi, Maroof Ahmed Khan

“…EtCO2 measurement was done using mainstream capnography in both intubated and nonintubated patients at presentation and at 120 min of resuscitation. Heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure (MAP), respiratory rate, oxygen saturation, and laboratory parameters (lactate, base deficit [BD], and partial pressure of carbon dioxide) were measured at the same time points. …”
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Xenon as a Component of Anesthetic Maintenance for Early Activation of Patients after Myocardial Revascularization by Ye. V. Dzybinskaya, O. V. Stepanova, I. A. Kozlov

“…Lower Pa02 after initiation of xenon inhalation and, accordingly, decreased Fi02 were not associated with worse Pa02/Fi02 and increased intrapulmonary blood shunting; there were no changes in blood oxygen-transport function. …”
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FEATURES OF CHEMILUMINESCENT ACTIVITY OF NEUTROPHILIC GRANULOCYTES IN PATIENTS WITH CHRONIC GASTRITIS, CHRONIC ATROPHIC GASTRITIS AND GASTRIC CANCER by O. V. Smirnova, V. V. Tsukanov, A. A. Sinyakov

“…Chemiluminescent activity of NG is increased in the group of CAG patients, and, considering similar changes in activation time and area under the curve, NG also produce greater amount of reactive oxygen species. Thus, for all H.pylori-associated diseases, the blood NG take longer time to activate, whereas their functional activity is not disturbed in CG, enhanced in CAG patients, and reduced in gastric cancer.…”
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ERYTHROPOIESIS REACTION TO TUMOR GROWTH IN LUNG CANCER PATIENTS by Y. A. Ragulin, O. S. Izmestieva, V. V. Vapnyar, N. V. Severskaya, M. V. Poluektova, S. E. Glebova, I. L. Ershova, V. N. Derbugov, L. P. Zhavoronkov

“…In addition to the transport of oxygen in tissues, erythrocytes participate in maintaining homeostasis therefore their qualitative and quantitative characterization may reflect a number of changes occurring in the body. …”
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PERSONALIZED PHARMACOLOGICAL CORRECTION OF IMMUNE SYSTEMS, METABOLIC AND NEUROPSYCHIC PARAMETERS IN CHRONIC BRAIN ISCHEMIA OF STAGE I AND II ON THE BACKGROUND OF HYPERTENSION DISEA... by A. I. Konoplya, A. A. Shulginova, N. A. Bystrova, V. P. Gavrilyuk, G. N. Ryzhikova

“…The sorption capacity of erythrocytes and the sorption capacity of the glycocalyx (SEG), the activity of lipid peroxidation processes, the state of the antioxidant system were determined in blood plasma and erythrocytes, the level of stable metabolites of nitric oxide (SMNO), neopterin, C-reactive protein, cytokines (TNFα, IL-1β, IL-8, IFNγ, IL-18, G-CSF, IL-4, IL-10), immunoglobulins (IgM, IgG, IgA), complement system components (C3, C4, C5, C5A), phagocytic and oxygen-dependent activity of polymorphonuclear blood leukocytes. …”
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From vulnerability to resilience: unraveling the role of oxidative stress in preterm brain injury by Qianqian Jiang, Jialin Wen, Yingxue Ding, Hong Cui

“…In preterm infants, OS is particularly detrimental due to their underdeveloped antioxidant systems, high brain metabolic demands, immature blood-brain barrier (BBB), and increased vulnerability to inflammation and hypoxia. …”
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Acute coronary syndrome in COVID-19 patients by M. G. Chashchin, A. Yu. Gorshkov, O. M. Drapkina

“…Acute coronary syndrome (ACS) is caused by an acute mismatch between myocardial oxygen demand and its supply. This mechanism is largely associated with the progression of coronary atherosclerosis in combination with an inflammatory response, hypoxemia, and blood procoagulation. …”
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An Analysis of Proposed Etiological Factors for Sudden Spike in Mucormycosis Infection During COVID-19 Pandemic at a Tertiary Hospital of North India by Akhil Pratap Singh, Prabhat Agrawal, Vikas Kumar

“…Of the total 88 patients, 42 (47%) were on oxygen therapy, 72 (81%) had history of blood transfusion, and 48 (54%) were given steroids. …”
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Advancing shock prediction: leveraging prior knowledge and self-controlled data for enhanced model accuracy and generalizability by Cheng-Yu Tsai, Xiu-Rong Huang, Po-Tsun Kuo, Tzu-Tao Chen, Yun-Kai Yeh, Kuan-Yuan Chen, Arnab Majumdar, Chien-Hua Tseng

“…A total of 299 features were derived: 90 from arterial blood pressure (ABP), 89 from electrocardiogram (ECG), 112 from respiratory waveforms (RESP), and 8 from blood oxygen saturation (SpO2). …”
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Case Report: A case series of using ultrasound-guided continuous parasacral ischial plane blocks to promote ulcer healing and pain relief in people with diabetic foot ulcers by Peng Ye, Peng Ye, Xuan Pan, Jing Zhuang, Hanliang Fan, Xiaochun Zheng, Xiaochun Zheng, Ting Zheng

“…Chronic non-healing DFU often result from peripheral neuropathy, microvascular issues, and infection, with poor blood and oxygen supply being critical factors in delayed healing. …”
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Risk Factors for Postoperative Encephalopathies in Cardiac Surgery by A. N. Shepelyuk, T. V. Klypa, Yu. V. Nikiforov

“…In this group, cerebral oxygenation (CO) was significantly lower (64±1.41 and 69.9±0.38%). …”
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The effect of four weeks of polarized training on aerobic fitness and performance of professional rowers by Tahereh Hozouri, Mohammad Fashi, Hamidollah Hassanlouie

“…Before and after the training period, maximal oxygen consumption, respiratory exchange ratio, blood lactate, time of 2000 and 1000 meters were evaluated. …”
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