Genomic Comparisons Revealed the Key Genotypes of <i>Streptomyces</i> sp. CB03234-GS26 to Optimize Its Growth and Relevant Production of Tiancimycins by Huiming Liu, Jing Lin, Yong Huang, Yanwen Duan, Xiangcheng Zhu

“…Four target genes were selected for further bioinformatic analyses and genetic validations. …”
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Effect of ondansetron for preventing of ovarian hyperstimulation syndrome: in an experimental rat model by Şükrü Bakırcı, Nevin Sağsöz, Tuba Devrim, Yaşar Şahin, Murat Bulanık, Hilal Gözüyukarı

“…Serotonin is said to have similar effects to VEGF . Ondansetron is Selective Serotonin (5-HT3) Receptor Antagonist . It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. …”
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Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver. by Yuqing Wang, Ayrea Hurley, Marco De Giorgi, Mark R Tanner, Rong-Chi Hu, Michael W Pennington, William R Lagor, Christine Beeton

“…Several of its analogs are some of the most potent and selective blockers of this channel. However, like most biologics, ShK and its analogs require injections for their delivery, and repeated injections reduce patient compliance during the treatment of chronic diseases. …”
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Mobile Robot Positioning with Wireless Fidelity Fingerprinting and Explainable Artificial Intelligence by Hüseyin Abacı, Ahmet Çağdaş Seçkin

“…As a result, even when positioning was conducted with only seven selected Wi-Fi access points, the MAE value was found to be 0.811 for the <i>x</i>-axis, 0.492 for the <i>y</i>-axis, and 0.134 for the Z-axis, respectively.…”
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Early pulmonary rehabilitation of COVID-19 patients in an isolation ward and intensive care unit by Chou-Chin Lan, Po-Chun Hsieh, Mei-Chen Yang, Wen-Lin Su, Chih-Wei Wu, Hsiang-Yu Huang, Yao-Kuang Wu

“…In order to achieve safe training, criteria for selecting stable patients and training termination are important. …”
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Questvertising as a new format of interactive advertising by Dariusz Dolinski, Tomasz Grzyb

“…Ad avoidance is one of the most persistent challenges in online advertising, with users increasingly employing ad-blocking software or developing habitual strategies to ignore marketing content. …”
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Optimal filter assignment policy against link flooding attack by Rajorshi Biswas, Jie Wu, Wei Chang, Pouya Ostovari

“…In this paper, we formulate two optimization problems for blocking the least number of PCLs so that the legitimate traffic goes through a non-congested path. …”
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Adaptation of the REINVENT neural network architecture to generate potential HIV-1 entry inhibitors by D. A. Varabyeu, A. D. Karpenko, A. V. Tuzikov, A. M. Andrianov

“…Of the 52,000 compounds selected, about 34,000 molecules satisfy the restrictions imposed on a potential drug to ensure its bioavailability when taken orally.Conclusion. …”
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Open bibliographic databases: in search of an alternative to Scopus and the Web of Science by I. D. Turgel, O. A. Chernova

“…A comparative analysis is conducted on selected open databases to assess their suitability for different stages of scientific knowledge production. …”
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Inconsistency-driven approach for human-in-the-loop entity matching by Hiroyoshi Ito, Takahiro Koizumi, Ryuji Yoshimoto, Yukihiro Fukushima, Takashi Harada, Atsuyuki Morishima

“…The result showed that the inconsistency-based sampling selects very different entity pairs compared to other sampling strategies and that a simple hybrid strategy performs well in many practical situations. …”
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PNH TREATMENT: TREATMENTS OF TODAY AND TOMORROW by Zeynep Tuğba Güven

“…Pegcetacoplan is a C3 inhibitor that is administered subcutaneously, twice weekly, and is capable of blocking both intravascular and extravascular hemolysis.5Iptacopan, an oral inhibitor of factor B (a component of the alternative complement pathway) was approved by the FDA in 2023. …”
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Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3. by Jeffrey A Alten, Ana Moran, Anna I Tsimelzon, Mary-Ann A Mastrangelo, Susan G Hilsenbeck, Valeria Poli, David J Tweardy

“…Pre-treatment of rats with a selective inhibitor of Stat3, T40214, reduced the IL-6-mediated increase in cardiac Stat3 activity, blocked successful resuscitation by IL-6 and reversed IL-6-mediated protection from cardiac apoptosis. …”
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In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis. by Michael A Colman, Haibo Ni, Bo Liang, Nicole Schmitt, Henggui Zhang

“…In addition, as IKur is an atrial-specific channel and a number of IKur-selective blockers have been developed as anti-AF agents, this study also helps to understand some contradictory results on both pro- and anti-arrhythmic effects of blocking IKur.…”
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Finger Vein Recognition Using Optimal Partitioning Uniform Rotation Invariant LBP Descriptor by Bang Chao Liu, Shan Juan Xie, Dong Sun Park

“…In this paper, we proposed two block selection methods which are based on the estimate of the amount of information in each block and the contribution of block location by looking at recognition rate of each block position to reduce feature extraction time and matching time. …”
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Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy by James Dooley, Bart Neyns, Elizabeth Allen, Frank Tacke, Louis Boon, Damya Laoui, Julia Katharina Schwarze, Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Madeleine Rachel Bardet, Gillian Blancke, Maude Jans, Evangelia Bolli, Maria Solange Martins, Yvon Elkrim, Kiavash Movahedi, Niels Vandamme, Sebahat Ocak, Isabelle Scheyltjens, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, Jo Agnes Van Ginderachter

“…These Nbs were formulated as tetravalent Nb-Fc fusion proteins for optimal CCR8 binding and blocking, containing either an antibody-dependent cell-mediated cytotoxicity (ADCC)-deficient or an ADCC-prone Fc region. …”
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Design of an Automatic Defect Identification Method Based ECPT for Pneumatic Pressure Equipment by Bo Zhang, YuHua Cheng, Chun Yin, Xuegang Huang, Sara Dadras, Hadi Malek

“…The data block selection and variable step search are integrated to decrease the redundant computations in the automatic defect identification. …”
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BiVO₄-Based Photoelectrochemical Sensors for the Detection of Diclofenac: The Role of Doping, Electrolytes and Applied Potentials by Milda Petruleviciene, Irena Savickaja, Jelena Kovger-Jarosevic, Monika Skruodiene, Jurga Juodkazyte, Simonas Ramanavicius, Arunas Ramanavicius

“…However, at higher concentrations, saturation of diclofenac was observed at the photoelectrode/electrolyte interface. The results of selectivity experiments demonstrated that the nature of the electrolyte has a significant impact on the selectivity of designed photoelectrochemical sensors.…”
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Variability in total antioxidant capacity, antioxidant leaf pigments and foliage yield of vegetable amaranth by Umakanta Sarker, Md Tofazzal Islam, Md Golam Rabbani, Shinya Oba

“…Twenty vegetable amaranth genotypes were evaluated for total antioxidant capacity, antioxidant leaf pigments, vitamins, and selection of suitable genotypes for extraction of juice in a randomized complete block design (RCBD) with three replications. …”
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Targeted mutagenesis on PDGFRα-Fc identifies amino acid modifications that allow efficient inhibition of HCMV infection while abolishing PDGF sequestration. by Svenja Feldmann, Immanuel Grimm, Dagmar Stöhr, Chiara Antonini, Peter Lischka, Christian Sinzger, Cora Stegmann

“…PDGFRα-Fc with this mutation was fully effective at blocking HCMV entry and had a drastically reduced affinity for PDGF-BB. …”
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Characteristics of Plasmodium vivax apicomplexan amino acid transporter 8 (PvApiAT8) in the cationic amino acid transport by Wang-Jong Lee, Ernest Mazigo, Jin-Hee Han, Seok Ho Cha

“…A promising new treatment aimed at targeting P. vivax involves blocking cationic amino acid uptake, which is a biological source of nutrients for the parasite. …”
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