Evaluation of a Myoelectrical Arm for Transradial Amputation in Functional Activities by Michael Tobias, Oluwasola Okhuoya, Jamelia Ancel, Michelle Intintoli, Lara A. Thompson, Ji Chen

“…One outcome measure that showed improvement across most tasks was the task completion time, which, on average, for the targeted Box and Block Test (tBBT) task was reduced by 24.0 s, box lifting by 1.6 s, bottle pouring by 9.0 s, and the pulley task by 8.4 s. …”
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Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance by Amanda L. Waterbury, Jonatan Caroli, Olivia Zhang, Paloma R. Tuttle, Chao Liu, Jiaming Li, Ji Sung Park, Samuel M. Hoenig, Marco Barone, Airi Furui, Andrea Mattevi, Brian B. Liau

“…Recently, next-generation precision LSD1 covalent inhibitors have been developed, which selectively block LSD1 enzyme activity by forming a compact N-formyl flavin adenine dinucleotide (FAD) adduct that spares the GFI1B interaction. …”
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PI3K-dependent GAB1/Erk phosphorylation renders head and neck squamous cell carcinoma sensitive to PI3Kα inhibitors by Xu Zhang, Jiao Xu, Xuan Wang, Lan Xu, Xi Zhang, Yi Wang, Shujuan Jiang, Yixiang Zhang, Jian Ding, Chen Qing, Linghua Meng

“…CYH33 is a novel PI3Kα-selective inhibitor discovered by our group, which is currently undergoing a phase I clinical trial (NCT03544905) for the treatment of advanced solid tumors including HNSCC. …”
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Assessment of Field Performance and Nutritional Quality of Mung Bean (Vigna radiata L.) for Food Diversification by Qudrah Oloyede-Kamiyo, Paul Ukachukwu, Mayowa Oladipo, Oyeyoyin Olanipekun, Adedotun Adewumi

“…The experiment was established according to randomized complete block design with three replications. Agronomic and yield data were collected. …”
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Evaluation of reservoir environment by chemical properties of reservoir water‒A case study of Chang 6 reservoir in Ansai oilfield, Ordos Basin, China by Zhi-bo Zhang, Ying Xu, Di-fei Zhao, Hao-ming Liu, Wei-cheng Jiang, Dan-ling Chen, Teng-rui Jin

“…The authors tested and analyzed the chemical characteristics of water samples selected from 30 wells in the Chang 6 reservoir of Ansai Oilfield in the Ordos Basin. …”
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Evaluation of multiple SAR speckling filter techniques performance in irrigated rice areas by A. D. B. Garcia, A. D. B. Garcia, A. D. B. Garcia, J. Jr. Celeste, I. Cheng, I. Cheng, V. H. R. Prudente, I. D. Sanches, I. D. Sanches

“…These findings highlight the importance of selecting appropriate filtering techniques for accurate agricultural monitoring using SAR data.…”
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Physiological and Biochemical Responses of Almond (<i>Prunus dulcis</i>) Cultivars to Drought Stress in Semi-Arid Conditions in Iran by Esmaeil Safavi Bakhtiari, Asghar Mousavi, Mehrab Yadegari, Bijan Haghighati, Pedro José Martínez-García

“…Identifying and selecting almond cultivars with drought tolerance traits is crucial for developing more resilient cultivars, especially in regions prone to water scarcity or facing changing climate conditions. …”
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Effects of Rhythmic and Simple Auditory Stimulations on Learning the Timing of Sequential Motor Task in Children With DCD by Ahmad Dehnavi, Alireza Saberi Kakhaki, Hamidreza Taheri Torbati, Mohammadreza Shahabi Kaeb

“…Next, the training protocol was presented in 10 blocks of 5 attempts and the acquisition test was performed. …”
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Oral microbiota-regulating and inflammation-targeted polymersome-hydrogels for RNAi therapy of ulcerative colitis by Huan He, Xinyi Dong, Li Cao, Yongjie Sha, Yinping Sun, Songsong Zhao, Fenghua Meng, Zhiyuan Zhong

“…Remarkably, GA-siTNFα-PS/SHE-Gel not only effectively blocks the progression of inflammation but also maintains the homeostasis of gut microbiota in the ulcerative colitis model. …”
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Stability of anthocyanin, carotenoid and root yield of 10 sweet potato genotypes by Aninbon Chorkaew, Surach Noppadol, Phungam Nittaya, Janket Anon, Bunphan Darika, Charirak Punyisa, Ruttanaprasert Ruttanachira

“…Information on the levels and variability of phytochemicals in sweet potato enables breeders to select sweet potato genotypes with high and stable phytochemicals for sweet potato breeding.…”
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FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines by Ke Su, Ping Zeng, Wei Liang, Zhengyu Luo, Yiman Wang, Xifeng Lv, Qi Han, Miao Yan, Cheng Chen

“…FTY720 is a synthetic S1P analog which can block S1P evoking physiological effects. Recently studies show that S1P was participating in activated inflammation cells induced renal injury. …”
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Assessing phenotypic variability and environmental interactions in wheat (Triticum aestivum) using the Eberhart and Russell Model by PARAS, MOHINDER SINGH DALAL, YOGENDER KUMAR, V S MOR, SUMAN DEVI, SONU LANGAYA, MUKESH KUMAR POONIA, HARSH CHAURASIA

“…The trial was conducted in randomized complete block design (RCBD). Significant genotype-by-environment (G × E) interactions were observed, underscoring the importance of selecting stable, high-yielding genotypes. …”
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A ROS‐Responsive Dual‐Targeting Drug Nanocarrier Serving as a GSI Synergist and Ferroptosis Sensitizer for T‐Cell Acute Lymphoblastic Leukemia by Ruinan Jia, Yang Liu, Jilong Xiao, Yuan Xia, Xin Zhao, Huixian Ma, Jingjing Ye, Zhiyue Zhang, Tao Sun, Chunyan Ji

“…Although γ‐secretase inhibitors (GSIs) can block Notch1 activation, their clinical application is limited by side effects and reduced sensitivity. …”
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Experimental Study on the Effective Utilization of Reserves in Tight Sandstone Gas Reservoirs and Their Applications by Jie Zhang, Feifei Fang, Weijun Shen, Huaxun Liu, Shusheng Gao, Liyou Ye

“…For this purpose, long cores on the Su 6 block of Sulige tight sandstone gas field in China were selected, and a multipoint embedded measurement system was established to study the characteristics of effective reserve utilization. …”
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Dynamic Heart Rate Variability Vector and Premature Ventricular Contractions Patterns in Adult Hemodialysis Patients: A 48 h Risk Exploration by Gabriel Vega-Martínez, Francisco José Ramos-Becerril, Josefina Gutiérrez-Martínez, Arturo Vera-Hernández, Carlos Alvarado-Serrano, Lorenzo Leija-Salas

“…The hour with the highest PVCs occurrence was identified and used to assess HRV fluctuations and segmented into 5 min blocks with a 0.77 min overlap, yielding a dynamic HRV vector, one for each of seven HRV indices selected to evaluate autonomic nervous system balance. …”
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Biocatalytic production of 3-hydroxypropionic acid precursors using a regioselective Baeyer-Villiger monooxygenase by Melissa De Angelis, Danilo Correddu, Fabio Bucciol, Silvia Tabasso, Gianluca Catucci, Giancarlo Cravotto, Carlo Roggero, Gianfranco Gilardi, Sheila J. Sadeghi

“…Some BVMOs can convert cellulose-derived alkyl levulinates to 3-acetoxypropionates (3-APs), which are key intermediates in the production of 3-hydroxypropionic acid (3-HP), a versatile building block chemical. In this study, a BVMO from Acinetobacter radioresistens (Ar-BVMO) was tested as a biocatalyst for the conversion of three marketed alkyl levulinates: methyl, ethyl and butyl levulinate. …”
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FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis by Hamza M Al‐Tamari, Swati Dabral, Anja Schmall, Pouya Sarvari, Clemens Ruppert, Jihye Paik, Ronald A DePinho, Friedrich Grimminger, Oliver Eickelberg, Andreas Guenther, Werner Seeger, Rajkumar Savai, Soni S Pullamsetti

“…Activation of FoxO3 with UCN‐01, a staurosporine derivative currently investigated in clinical cancer trials, reverted the IPF myofibroblast phenotype in vitro and blocked the bleomycin‐induced lung fibrosis in vivo. …”
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Fabrication of an In Situ pH-Responsive Raloxifene-Loaded Invasome Hydrogel for Breast Cancer Management: In Vitro and In Vivo Evaluation by Hanan O. Farouk, Marwa M. Nagib, Amr Gamal Fouad, Demiana M. Naguib, Sherif Faysal Abdelfattah Khalil, Amany Belal, Samar F. Miski, Nisreen Khalid Aref Albezrah, Shatha Hallal Al-Ziyadi, Gi-Hui Kim, Ahmed H. E. Hassan, Kyung-Tae Lee, Doaa S. Hamad

“…Background/Objectives: Raloxifene (RLF) is a therapeutic option for invasive breast cancer because it blocks estrogen receptors selectively. Low solubility, limited targeting, first-pass action, and poor absorption are some of the challenges that make RLF in oral form less effective. …”
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Betacoronaviruses SARS-CoV-2 and HCoV-OC43 infections in IGROV-1 cell line require aryl hydrocarbon receptor by Meisam Yousefi, Wai Suet Lee, Wharton O. Y. Chan, Wei He, Marcus G. Mah, Cythia Lingli Yong, Joshua M. Deerain, Lijin Wang, Camille Arcinas, Biaoguo Yan, Dewei Tan, Wan Rong Sia, Akshamal M. Gamage, Jinxuan Yang, Alan Chen-Yu Hsu, Shang Li, Martin Linster, Xinglou Yang, Sujoy Ghosh, Danielle E. Anderson, Gavin J. D. Smith, Chee Wah Tan, Lin-Fa Wang, Yaw Shin Ooi

“…Using DiMNF, a small molecule inhibitor of AHR, we observed that the drug selectively inhibits HCoV-OC43 infection but not SARS-CoV-2. …”
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Geological and reservoir modelling of coalbed methane in Karadon Region of Zonguldak Basin (Türkiye): A case study by Demet Banu Koralay, Turhan Ayyildiz, Mehmet Sıddık Kızıl, Sofiane Belhocine, Muhammed Emin Bulguroğlu

“…As aresult, a 5-wells configuration also known as the “5 spot wells” layout is selected. Five wells will be in the same well pad but deviated 600 meters distance in target zones. …”
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