The Pharmacological Evidences for the Involvement of AhR and GPR35 Receptors in Kynurenic Acid-Mediated Cytokine and Chemokine Secretion by THP-1-Derived Macrophages by Katarzyna Sawa-Wejksza, Jolanta Parada-Turska, Waldemar Turski

“…In the present study, the effects of KYNA on the secretion of selected cytokines and chemokines by macrophages derived from the human THP-1 cell line are investigated. …”
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Effects of Three Different Fibrates on Intrahepatic Cholestasis Experimentally Induced in Rats by Alaa El-Sisi, Sahar Hegazy, Eman El-Khateeb

“…In groups which received GW6471, these effects were completely abolished with fenofibrate and partially blocked with bezafibrate and gemfibrozil. Conclusion. …”
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Rebalancing agents in hemophilia: knowns, unknowns, and uncertainties by Quentin Van Thillo, Cédric Hermans

“…Other promising rebalancing agents are concizumab and marstacimab, which selectively bind to the K2 domain of the tissue factor pathway inhibitor, thus restoring thrombin generation. …”
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Activation of Brainstem Pro-opiomelanocortin Neurons Produces Opioidergic Analgesia, Bradycardia and Bradypnoea. by Serena Cerritelli, Stefan Hirschberg, Rob Hill, Nina Balthasar, Anthony E Pickering

“…All effects of NTSPOMC activation were blocked by systemic naloxone (opioid antagonist) but not by SHU9119 (melanocortin receptor antagonist). …”
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UCSwin‐UNet model for medical image segmentation based on cardiac haemangioma by Jian‐Ting Shi, Gui‐Xu Qu, Zhi‐Jun Li

“…We incorporated a U‐shaped convolutional neural network block into the original jump connection of Swin‐UNet. …”
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Application status and development direction of optimal injection allocation method for water injection wells by LUO Xianbo,CHANG Huijiang,LEI Yuan,ZHAI Shangqi,SUN Guangyi

“…This new idea emphasizes that for the optimal injection allocation of the water injection wells, the optimal injection parameter calculation method should be selected according to different geological reservoir characteristics, oilfield development stages, injection accuracy and other factors, so that to make the oilfield optimized water injection effect best. …”
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The release of nitric oxide from S-nitrosothiols promotes angiogenesis. by Bahjat Al-Ani, Peter W Hewett, Suborna Ahmed, Melissa Cudmore, Takeshi Fujisawa, Shakil Ahmad, Asif Ahmed

“…Surprisingly, DTT maintained endothelial tube networks for up to one month under serum-free conditions, and selective inhibitors of guanylyl cyclase (ODQ) and PKG (KT-5823) blocked this, demonstrating the requirement of cyclic GMP and PKG in this process.…”
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“Financial Stability”: A Nightmare for Retired Healthcare Professionals in Southwestern Nigeria: An Interpretative Phenomenology by Aderonke Julienne Adetunji MSc, BNSc, RPHN, RNE, RM, RN, Emelda Zandile Gumede PhD, Mcur, RNE, RM, RN

“…Retirees opted for alternative means of income, like petty trading, Tuck shops, molding blocks, livestock-rearing goats, and working in private institutions. …”
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Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. by Vera J E van Vliet, Nhan Huynh, Judith Palà, Ankoor Patel, Alex Singer, Cole Slater, Jacky Chung, Mariska van Huizen, Joan Teyra, Shane Miersch, Gia-Khanh Luu, Wei Ye, Nitin Sharma, Safder S Ganaie, Raquel Russell, Chao Chen, Mindy Maynard, Gaya K Amarasinghe, Brian L Mark, Marjolein Kikkert, Sachdev S Sidhu

“…Here we demonstrate that ubiquitin variants (UbVs) can be selected from a phage-displayed library and used to specifically and potently block SARS-CoV-2 PLpro activity. …”
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A reduced-dimensionality approach to uncovering dyadic modes of body motion in conversations. by Guy Gaziv, Lior Noy, Yuvalal Liron, Uri Alon

“…We find evidence of dyad individuality in the use of motion modes. For a randomly selected subset of 5 dyads, this individuality was maintained for at least 6 months. …”
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Performance of Garden Pea Progenies for their Growth and Yield Characteristics in Mid Hills of Himachal Pradesh by Sandeep Kumar, Viveka Katoch, Akanksha Bharti

“…Observations were recorded for pod yield and related horticultural traits on ten randomly selected plants. On the basis of mean performance, cross line 17×Palam Triloki showed significantly best results for early traits viz., first flowering and days to 50% flowering. …”
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Production of HMF-derivatives from wine residues using Saccharomyces cerevisiae as whole-cell biocatalyst by Joana T. Cunha, Aloia Romaní, Lucília Domingues

“…Transitioning to a bio-based economy requires prioritizing chemical production processes that utilize renewable resources, ensuring sustainability and environmental responsibility. 5-Hydroxymethylfurfural (HMF) and its derivatives are promising building blocks, ranked among the top 12 bio-based molecules derived from biomass. …”
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Targeting hyperlipidemia: A polarity-driven ternary extraction of Apium graveolens bioactives—A coupled in-vivo, in-vitro and in-silico investigation by Nargis Sultana Chowdhury, Tasnuva Sharmin Zaman, Rifah Noor Chowdhury, Md Abdur Rahman, Sheikh Rakibul Alam, Romana Akter, Md. Nazmus Samdani, Syeda Sadia Afrin, Md. Rafat Tahsin, Fahima Aktar, Ishrat Jahan, Nasiba Binte Bahar, Salehuddin Ayubee, Umme Habiba Ria, Md Zakir Sultan, Mohammad Borhan Uddin, Jakir Ahmed Chowdhury, Md. Selim Reza, Abu Asad Chowdhury, Shaila Kabir, Md. Shah Amran

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Multi-Source Attention U-Net: A Novel Deep Learning Framework for the Land Use and Soil Salinization Classification of Keriya Oasis in China with RADARSAT-2 and Landsat-8 Data by Yang Xiang, Ilyas Nurmemet, Xiaobo Lv, Xinru Yu, Aoxiang Gu, Aihepa Aihaiti, Shiqin Li

“…A salinized soil classification dataset was developed by combining spectral indices obtained from Landsat-8 Operational Land Imager (OLI) data and polarimetric scattering features extracted from RADARSAT-2 data using polarization target decomposition. To select optimal features, the Boruta algorithm was employed to rank features, selecting the top eight features to construct a multispectral (MS) dataset, a synthetic aperture radar (SAR) dataset, and an MS + SAR dataset. …”
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SUMO2/3 modification of transcription-associated proteins controls cell viability in response to oxygen and glucose deprivation-mediated stress by Francisco Gallardo-Chamizo, Román González-Prieto, Vahid Jafari, Noelia Luna-Peláez, Alfred C. O. Vertegaal, Mario García-Domínguez

“…Conversely, sumoylation of the pluripotency factor OCT4, which is sumoylated under OGD, and is a target of the SUMO protease SENP7 for desumoylation after ROG, seems to block its cell survival-promoting capacity. Thus, better outcomes in cell protection would rely on the appropriate combination of sumoylated and non-sumoylated forms of selected factors.…”
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Effect of Mobile-based Breastfeeding Education on Breastfeeding Experience of Mothers: A Quasi-Experimental Study by Mona Aram, Sedighe Rezaie-Chamani, Zahra Bostani Khalesi, Saman Maroufizadeh

“…Materials and Methods: This quasi-experimental study included 81 nursing mothers selected using a multi-stage cluster random sampling method from selected comprehensive health centers in Rasht, Iran. …”
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Activation of cannabinoid CB1 receptors suppresses HCN channels function in dorsal root ganglion neurons of rats by Xiaolu Lei, Meiyun Chen, Xingfeng Liu, Yan Yan, Xupeng Li, Fei Gong, Deqian Yu, Xiaohong Liu

“…In this study, we investigated the effect of ACEA, a selective agonist for CB1R, on HCN channel expression and function in the DRG of rats with chronic constriction injury (CCI) of the sciatic nerve. …”
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Static pressure prediction method for CO2 flooding oil reservoirs based on time series partitioning Transformer model by LI Chunlei, YANG Heshan, ZHANG Hongxia, CAO Yumin, JIANG Xingxing, JIN Caixia

“…Model parameters were selected based on correlation analysis， and iterative interpolation was used to fill in samples to construct a static pressure prediction sample set. …”
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Factors and applications of carbon dioxide huff-and-puff technology in small toothbrush-shaped oil reservoirs by Jinyong Li, Hongyu Gong, Qin Qin, Rui Wu

“…However, its application in complex, small-block reservoirs presents significant challenges owing to their limited size and intricate oil–water systems. …”
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Morphological characterization and biostimulation of growth, production, and quality of ‘chiltepín’ (Capsicum annuum var. glabriusculum) using an agroecological approach by Karina Crisalyn IBARRA-LEGARDA, Loreto ROBLES-HERNÁNDEZ, Rocío INFANTE-RAMÍREZ, Ana Cecilia GONZALEZ-FRANCO, María Carmen E. DELGADO-GARDEA, Jared HERNÁNDEZ-HUERTA

“…The study was conducted using a completely randomized block design with four treatments (T1-BF, T2-RT, T3-RB, and T4-Ctrl), four replications, and five plants per experimental unit. …”
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