Overview of Inflammatory Bowel Disease Pathogenesis by C Fiocchi

“…While most immune abnormalities detected in patients with established disease are likely to represent secondary events, these are no less important, as they probably contribute to the perpetuation of gut inflammation and tissue damage. …”
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ZIP7 contributes to the pathogenesis of diabetic cardiomyopathy by suppressing mitophagy in mouse hearts by Ningzhi Yang, Rui Zhang, Hualu Zhang, Yonghao Yu, Zhelong Xu

“…Mitophagy was assessed by detecting mito-LC3II, mitoKeima, and mitoQC. Reactive oxygen species (ROS) were detected with DHE and mitoB. …”
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Dust Aerosol Classification in Northwest China Using CALIPSO Data and an Enhanced 1D U-Net Network by Xin Gong, Delong Xiu, Xiaoling Sun, Ruizhao Zhang, Jiandong Mao, Hu Zhao, Zhimin Rao

“…Dust aerosols were predominantly detected between 0.44 and 4 km, consistent with observations from CALIPSO. …”
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The obstetrical management of HIV-positive pregnancy by Mihai George Loghin, Petre Gabriel Gorescki, Romina Marina Sima, Liana Pleș, Daniela Gabriela Balan, Ioana Paunica, Oana Denisa Bălălău

“…Due to the antiretroviral treatment, the progression of the disease is blocked during the period of asymptomatic infection, and the risk of neonatal transmission is very low. …”
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Metformin inhibits migration and invasion of renal carcinoma cell line 786-O by regulating acetylation of histone by HE De-jiao, YANG Ding-ping, LIU Hong-yan, LI Hao-yong

“…Objective To investigate the mechanism of metformin inhibition of migration and invasion of renal carcinoma cell line 786-O.Methods Transwell migration and Matrigel invasion assays were used to examine the role of metformin at 10 mM and 20 mM on migration and invasion of the cell line 786-O.Expression of E-cadherin,vimentin,MMP-2 and MMP-9 as well as acetylation of histone H3 K9,H4 K12 and H4 K16 were detected by western blotting after metformin treatment.When combining the histone acetyltransferase inhibitor C646 with metformin,effect of metformin regulation of histone acetylation on migration of the cell line 786-O was observed through Transwell assay.Results Both 10 mM and 20 mM metformin remarkably inhibited migration and invasion of 786-O cells(P<0.05).The expression of E-cadherin was upregulated while expression of vimentin,MMP-2 and MMP-9 was downregulated after exposure to metformin(P<0.05).What’s more,the acetylation levels of histone H3 K9、H4 K12 and H4 K16 were significantly upregulated by metformin treatment(P<0.05).Combination of metformin with C646 could blocked inhibition of migration resulting from metformin treatment alone(P<0.05).Conclusions Metformin inhibits migration and invasion of renal carcinoma cell line 786-O through upregulation of histone acetylation.…”
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FONDUE—Fine-Tuned Optimization: Nurturing Data Usability & Efficiency by Valerie Restat, Indra Diestelkämper, Meike Klettke, Uta Störl

“…The choice of different optimization goals enables further flexibility, e.g. for environments with limited resources. As a first building block of FONDUE, we present CheDDaR, which is used to detect errors and measure data quality. …”
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Overexpression of Bruton Tyrosine Kinase Inhibits the Proliferation, Migration, and Invasion of Non-Small Cell Lung Cancer Cells by Wenjia Ren, Cheng Yue, Linjun Liu, Licheng Du, Ke Xu, Yubai Zhou

“…To further verify the above results, we detected the expression of the BTK gene in NSCLC cell lines A549, H1299, and H1650 at the RNA and protein levels by real-time fluorescent quantitative polymerase chain reaction and Western Blot analysis, respectively. …”
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Alzheimer's disease recognition via long-range state space model using multi-modal brain images by Ziyin Ren, Meng Zhou, Sadia Shakil, Raymond Kai-Yu Tong

“…Moreover, a feature fusion block is employed to consolidate features of different levels extracted by each encoder to generate fused feature maps. …”
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Conserving biogeographical units of endemic amphibians in the megadiverse Atlantic Forest by BRUNA E. BOLOCHIO, MARCELA BRASIL-GODINHO, CRISTIANO DE C. NOGUEIRA, RICARDO J. SAWAYA

“…Abstract The initial step in many biogeography approaches involves identifying biogeographical units, which serve as fundamental building blocks for understanding biodiversity patterns and guiding conservation efforts. …”
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Identification of the hemodynamic correlates of basic emotional states with a mobile functional near infrared spectroscopy system by Sinem Burcu Erdoğan

“…Each stimulus condition induced a distinct cortical activation pattern that could be identified with fNIRS.Conclusion: Our findings support the notion that different basic emotions have distinct localization and separable hemodynamic correlates in the prefrontal cortex region, which can be detected with a mobile fNIRS system. The distinct cortical hemodynamic activity patterns associated with each emotional state show the potential of fNIRS technology for decoding and differentiating basic emotions objectively and real time for future clinical and daily life applications.…”
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Phytochemical Investigation and Antioxidant Activity of Onopordum acanthium L. in Different Regions of Western Iraq Using GC-MS Analysis by Saba kamil thamer Ali

“…The outcomes showed a region-inducing, high variability in the chemical profile of this plant with active compounds in the range of 18 to 29, which is the highest number in Hit and Al-Karmah, indicating the richer biodiversity or favorable environmental conditions of the area. Compounds detected in all the regions included neovitadiene and hexadecanoic acid methyl ester, which are critical building blocks of the plant's metabolic framework for survival at different scales. …”
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The mystery of the missing P waves: a case report by Yuanguo Chen, Haibo Zhang, Changli Han, Peng Bai

“…Radiofrequency ablation achieved bidirectional isthmus block, restoring sinus rhythm (heart rate, 59 beats per minute) without pacemaker requirement. …”
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Masques et mascarades dans Romola par George Eliot : la traversée des apparences by Stéphanie Richet

“…What is at stake is not just the mask, easily detectable because codified, of social conventions. …”
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Efficacy of an oral narrative language intervention program on children with hearing impairment: a randomized controlled trial by Sara Ibrahim, Ossama Sobhy, Riham El-Maghraby, Nesrine Hamouda

“…The subjects were randomly divided by block randomization into two groups: group A (cases) which received training with the ONLIP and group B (control) which received conventional intervention for 3 months. …”
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Late Antique and Byzantine Doorframes of Ottoman Buildings in Bursa by Ayşın Özügül

“…This study aimed to document the jambs, lintels and lintel crowns in the aforementioned buildings, to evaluate them in detail, especially in terms of moulding profiles, and to offer date suggestions.Twelve moulding profiles, which distinguish from each other with small distinctions were detected in the doorframes, some of them belonging to the 5th and 6th centuries, while others to the Middle and Late Byzantine age. …”
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Chlorophyll a fluorescence in saccharine sorghum irrigated with saline water by Danilo R. Monteiro, Hidelblandi F. de Melo, Cintia M. T. Lins, Pablo R. M. Dourado, Hugo R. B. Santos, Edivan R. de Souza

“…Thus, estimating the damage to the photosynthetic apparatus caused by saline water is an important tool to detect abiotic stresses. For this purpose, sorghum plants were cultivated in a greenhouse and irrigated with two water sources (NaCl and salt mixture) with six levels of electrical conductivity (EC) (0, 2.5, 5, 7.5, 10, and 12.5 dS m-1), forming a 6 × 2 factorial in randomized blocks with four repetitions. …”
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Attention-fused residual transformer CNN for robust lower limb movement recognition by A. Anitha, D. Jeraldin Auxillia

“…Detecting lower limb movements from surface electromyography (sEMG) signals has received more attention, because of its importance in prosthetic control, robotic applications and medical rehabilitation. sEMG signals offer a non-invasive and accurate method to recognize movement intent. …”
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RELT Is Upregulated in Breast Cancer and Induces Death in Breast Cancer Cells by Maryann Batiste, Bethany Joy, Cara K. Yee, Luke Cho, Ashley Christensen, Ihab Abed, Kailey Nguyen, Anusri Yanumula, Hannah Chang, Evan D. Cho, Wenjia Wang, Emily Chou, Esther H. Chang, Yennie L. Shyu, Alyssa Abram, Jessa Alcaide, James Zhou, Brittany Gillespie, Michelle Senderovich, Gianne Almeida Cusick, Ai-Vy Le, Frank Hoang, Yihui Shi, Eslam Mohamed, John K. Cusick

“…RELT localization was detected through immunofluorescence and western blotting, and co-immunoprecipitation was used to test whether a mutated RELT interacts with the OXSR1 kinase. …”
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Prevalence of Rocahepevirus ratti (rat hepatitis E virus) in humans and rats in China by Xiuji Cui, Jianwen Situ, Ting Tang, Zhiyu Li, Dongzhui Chen, Stanley Siu-Fung Ho, Hiu-Laam Chung, Tsz-Chung Wong, Yonghao Liang, Chaowen Deng, Yongxian Su, Huijun Cai, Simon Kam-Fai Lo, Shiyao Huang, Sheng Zeng, Liyuan Zhang, Yunchun Chen, Shusheng Wu, Estie Hon-Kiu Shun, Nicholas Foo-Siong Chew, James Yiu-Hung Tsoi, Kelvin Hon-Yin Lo, Fanfan Xing, Vincent Chi-Chung Cheng, Kwok-Yung Yuen, Feifei Yin, Jasper Fuk-Woo Chan, Siddharth Sridhar

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Effect of a single prostaglandin F2α presynchrony 3 to 4 days prior to treatment of anestrous dairy cows with a novel intravaginal progesterone-releasing device and Ovsynch by S. McDougall, R.R. Munn, R. Castle

“…Cows (n = 1,557) not detected in estrus by 12 or 13 d before the start of the seasonal breeding program (d 0) and calved >13 d, were blocked within herd by lactation (i.e., primiparous vs. multiparous) and randomly assigned to treatment with Ulti-mate or CIDR devices, and presynchrony or not, in a 2 × 2 factorial design. …”
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