NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells by Fani Ziouti, Regina Ebert, Maximilian Rummler, Melanie Krug, Sigrid Müller-Deubert, Martin Lüdemann, Franz Jakob, Bettina M. Willie, Franziska Jundt

“…We further applied mechanical strain through cyclic stretching in human bone marrow-derived mesenchymal stromal cells (BMSCs) in vitro by using a bioreactor system and detected upregulation of NOTCH target gene expression. …”
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Synthesis and biological evaluation of new tri-heterocyclic derivatives as anti-colorectal cancer agents by Benjamin Victoir, Océane Pertegaz, Elfi Ducrocq, Marion Polomski, Maxime Guéguinou, William Raoul, Cécile Croix, Gildas Prié

“…Colorectal cancer is a major health problem, with a poor prognosis if not detected at early stage. It is the third most common cancer worldwide and the second most deadly. …”
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The Effects of Potato Golden Cyst Nematode Pathotype 2/3 On Plant Development in Clones and Varieties by Gülten Kaçar Avcı, Halil Toktay, Mustafa İmren, G.Badel Akyol, Ramazan Canhilal

“…The study was arranged in a randomized block design in the Alay district of Niğde province in 2021. …”
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Monitoring biological degradation of historical stone using hyperspectral imaging by Eva Matoušková, Kateřina Kovářová, Michal Cihla, Jindřich Hodač

“…Within our research, a historical sandstone block was analysed during time to monitor biological changes on the surface. …”
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Inoculation and co-inoculation of lettuce and arugula hydroponically influence nitrogen metabolism, plant growth, nutrient acquisition and photosynthesis by Carlos Eduardo da Silva Oliveira, Thaissa Julyanne Soares Sena Oliveira, Arshad Jalal, Guilherme Carlos Fernandes, Andréa de Castro Bastos, Andréa de Castro Bastos, Marcelo Rinaldi da Silva, Gabriela Rodrigues Sant’Ana, Jailson Vieira Aguilar, Liliane Santos de Camargos, Tiago Zoz, Marcelo Carvalho Minhoto Teixeira Filho

“…Greater nitrate reductase activity was detected in leaves, and lower nitrate accumulation was detected in lettuce and arugula under inoculations with A. brasilense, P. fluorescens and B. subtilis + P. fluorescens. …”
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Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway by Honghong Liu, Jiao Wang, Guanru Yue, Jixiong Xu

“…Moreover, downregulation of SIRT1 expression blocked the P-MSC-mediated enhancement of podocyte autophagy and improvement of podocyte injury. …”
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Leptin induces altered differentiation of keratinocytes by inducing insulin resistance: implications for metabolic syndrome-induced resistance of psoriatic therapy by Rui Wang, Chongli Yu, Zijie Tang, Jie Sun, Youlin Wang, Zhenkai Zhao, Biwen Lin, Chengxin Li

“…Leptin treatment up-regulated the mRNA and protein expression of SOCS3. Knockdown of SOCS3 blocked the effect of leptin-induced insulin resistance. …”
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Discovering leaf and stripe rust resistance in soft red winter wheat through genome‐wide association studies by John W. Bagwell, Mohamed Mergoum, Madhav Subedi, Suraj Sapkota, Bikash Ghimire, Benjamin Lopez, James W. Buck, Bochra A. Bahri

“…Using the Chinese Spring Reference Genome Version 1.0, we detected 16 candidate genes, and four known R genes and QTL overlapped two major QTL. …”
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Cathepsin B is up-regulated and mediates extracellular matrix degradation in trabecular meshwork cells following phagocytic challenge. by Kristine Porter, Yizhi Lin, Paloma B Liton

“…Higher levels of membrane-bound and secreted CTSB were also detected. Moreover, in vivo zymography showed the intralysosomal degradation of ECM components associated with active CTSB, as well as an overall increased gelatinolytic activity in phagocytically challenged TM cells. …”
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Approaches to vaccination of adults against pneumococcal disease in different countries of the world by A. S. Korovkin, Yu. I. Obukhov, E. N. Syatchikhina

“…Taking into account the spectrum of detected pneumococcal serotypes and molecular epidemiology data available in our country, the use of PCV20 can be considered justified.…”
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Measurement of Anti-Debugging Techniques on the Windows and Linux Operating Systems for the Intel x86_64 Architecture by Austin Norby, Bhaskar P. Rimal, Bramwell Brizendine

“…Malware authors also use these techniques to prevent their software from being analyzed, detected, or blocked. While anti-debugging techniques are not novel, there is minimal research on their performance. …”
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The Slx4-Rad1-Rad10 nuclease differentially regulates deletions and duplications induced by a replication fork barrier. by Marina K Triplett, Iffat Ahmed, Swathi Shekharan, Lorraine S Symington

“…Here, we established a direct repeat genetic reporter in Saccharomyces cerevisiae to detect recombination events that result in either a duplication or a deletion. …”
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Poly-β-hydroxybutyrate (PHB) Depolymerase from Fusarium solani Thom by Srividya Shivakumar

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Formation of a comprehensive rehabilitation program for patients considering the clinical and diagnostic features of the course of vertebral thoracic pain due to degenerative-dystr... by Ye. I. Maramukha

“…All patients had a functional block of the 2nd degree in the thoracic spine. They were divided into two groups. …”
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Analysis and Tracking of Intra-Needle Ultrasound Pleural Signals for Improved Anesthetic Procedures in the Thoracic Region by Fu-Wei Su, Chia-Wei Yang, Ching-Fang Yang, Yi-En Tsai, Wei-Nung Teng, Huihua Kenny Chiang

“…Glossary of Terms: intra-needle ultrasound (INUS); radio frequency (RF); short-time Fourier transform (STFT); intercostal nerve block (ICNB); paravertebral block (PVB); pulse repetition frequency (PRF).…”
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EXPERIMENTAL AND THEORETICAL MODELING OF DIAMONDIFEROUS PLUMES by A. G. Kirdyashkin, A. A. Kirdyashkin, V. Е. Distanov, I. N. Gladkov

“…While the thickness of the block above the plume roof decreases to a critical value xкр, the shear stress on its cylindrical surface reaches a critical value (strength limit) τкр.Rock fails in the vicinity of the cylindrical block and, as a consequence, the eruption conduit is formed. …”
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MiR-145-5p arrests the cell cycle by modulating SMAD5/cyclin D1 to inhibit gastric cancer progression by Li Wang, Li Wang, Jianghong Guo, Caixia Lv, Luke Kong, Luke Kong, Jing Cui, Zhongshuai Wang, Yuanyuan Guo, Ruirui Jia, Tao Guan, Tao Guan, Baofeng Yu, Feng Li

“…Immunohistochemistry was used to detect the expression of SMAD5 in GC tissues. Western blot was used to detect cell cycle-related proteins that were regulated by siRNA SMAD5.ResultsThe expression of miR-145-5p was lower in GC tissues and cells compared with adjacent tissues and GES-1, and was related to the poor prognosis of patients with GC. …”
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Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the Activity of α1,3-Fucosyltransferase by Yue Sun, Yun Guo, Jing Zhang, Lihua Chang, Haiyan Zhao, Xiaofei Wang

“…We also performed in vitro experiments with Sparstolonin B and detected changes in 1,3-fucosyltransferase activity by ELISA. …”
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Plastome and transcriptome analysis reveals a degenerated photosynthesis-related pathway in the mycoheterotrophic vanilloid orchid Cyrtosia lindleyana by Shiou Yih Lee, Peishan Zou, Zhihui Chen, Kenji Suetsugu, Wenbo Liao

“…Relative to Vanilla pompona, three genes, rpl23, rps14, and rps19, had undergone positive selection (Ka/Ks > 1), and gene-block inversions were detected in both the large and small single-copy regions. …”
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Comparative analysis of endoscopic submucosal dissection and surgical resection for early colorectal cancer by A. N. Sidorova, V. N. Klimenko, O. B. Tkachenko, M. V. Grinkevich, Yu. V. Petrik, O. V. Iaikova

“…In the endoscopic group, all tumors were removed in a single block. Radical removal was recognized in 80.7% of cases. …”
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