Study of the Level of Pro- and Antiangiogenic Growth Factors in Vitreous Fluid in Neovascular Age-Related Macular Degeneration on the Background of Treatment by M. M. Arkhipova, V. G. Likhvantseva, A. S. Gevorgyan, S. I. Rychkova, S. A. Selkov

“…In both groups of patients, antiangiogenic factors IFN-γ and TGF-β were practically not detected, but the concentration of IFN-α was significantly higher (6.4 ± 1.7 versus 4.4 ± 0.4, p < 0.01). …”
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Harnessing conversion bridge strategy by organic semiconductor in polymer matrix memristors for high‐performance multi‐modal neuromorphic signal processing by Weijia Dong, Xuan Ji, Chuanbin An, Chenhui Xu, Xuwen Zhang, Bin Zhao, Yuqian Liu, Shiyu Wang, Xi Yu, Xinjun Liu, Yang Han, Yanhou Geng

“…In this study, we introduce an efficient distribution of conversion bridges (EDCB) strategy by dispersing organic semiconductor (poly[2,5‐bis(3‐tetradecylthiophen‐2‐yl)thieno[3,2‐b]thiophene], PBTTT) in elastomer (polystyrene‐block‐poly(ethylene‐ran‐butylene)‐block‐polystyrene, SEBS). …”
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Determination of Favipiravir in Human Blood Plasma by HPLC-MS/MS by T. N. Komarov, P. A. Karpova, O. A. Archakova, D. S. Shchelgacheva, P. K. Karnakova, N. S. Bagaeva, K. Ya. Zaslavskaya, P. A. Bely, I. E. Shohin

“…Due to its structure, favipiravir is embedded in the RNA of the virus and blocks its further replication in the cell of the human body. …”
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Clinical characteristics, time course, treatment and outcomes of patients with immune checkpoint inhibitor-associated myocarditis by Edward J Spangenthal, Igor Puzanov, Marc S Ernstoff, Pankit Vachhani, Fumito Ito, Ankita Kapoor, Benjamin Switzer, Poornima Subramanian, Yan V Yatsynovich, David M Jacobs, Maya R Chilbert, Umesh C Sharma, Steven G Feuerstein, Filip Stefanovic, Mark D Hicar, Anne B Curtis, Grace K Dy, Brian J Page, Nikhil Agrawal, Arjun Khunger, Alexander Hattoum, Jerome J Schentag

“…Higher troponin I (p=0.016), CK (p=0.013), and CK-MB (p=0.034) levels were associated with increased mortality, while the presence of advanced atrioventricular block on presentation (p=0.088) trended toward increased mortality. …”
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Cardiovascular toxicities in cancer patients treated with immune checkpoint inhibitors: multicenter study using natural language processing on Belgian hospital data by D. Delombaerde, C.L. Oeste, V. Geldhof, L. Croes, I. Bassez, A. Verbiest, L. Tack, D. Hens, C. Franssen, P.R. Debruyne, H. Prenen, M. Peeters, J. De Sutter, C. Vulsteke

“…The CV AEs detected were heart failure (5.3%), atrial fibrillation (4.6%), myocardial infarction (2.0%), atrioventricular block (1.9%), myocarditis (1.2%), vasculitis (0.8%), pericarditis (0.4%), and Takotsubo cardiomyopathy (<0.3%). …”
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Survival and transfer of Escherichia coli to fresh produce from organically managed soils amended with poultry litter by Petrina McKenzie-Reynolds, Petrina McKenzie-Reynolds, Patricia Millner, Fawzy Hashem, Lurline Marsh, Brett Smith, Annette Kenney, Arthur Allen, Salina Parveen, Amy S. Collick

“…No other pathogens (Salmonella, Listeria monocytogenes, Staphylococcus aureus) were detected at 0 or 90 dpi in plot soils. Generic Ecrif-R was detected on four of 16 cantaloupes, four of 16 cucumbers from APL plots; four of 20 radish bulbs from till incorporated and four from subsurface-applied APL tested positive for gEcrif-R at 90 dpi. …”
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Assessing genetic diversity and heritability of effective traits on the yield of chickpea (Cicer arietinum L.) under rainfed condition by sayyed Saeed Moosavi, Mohammad Reza Abdollahi, Farzad Kian-ersi, Davood Ahmadi-Dehrashid

“…Conclusion Identifying and detection of the traits with high correlation with the traits of grain yield is a suitable strategy for indirect selection of grain yield. …”
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Evaluation of circulating cytokine concentrations and ex vivo indicators of the inflammatory response in transition dairy cows fed pre- and postpartum diets differing in metaboliza... by Trent A. Westhoff, Anja S. Sipka, Thomas R. Overton, Suzanne Klaessig, Sabine Mann

“…Serum concentrations of TNF were below the lower limit of detection (≤12 pg/mL) in 282 (75.4%) samples. Serum concentrations of IL-10 and IFN-γ were greatest at −6 d relative to calving. …”
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Discordance of 3rd and 4th generation QuantiFERON-TB Gold assays by pregnancy stages in India by Vandana Kulkarni, Mallika Alexander, Ramesh Bhosale, Divyashri Jain, Prasad Deshpande, Emily Shira Gitlin, Arthi Vaidyanathan, Andrea Chalem, Shilpa Naik, Nikhil Gupte, Neelu Nawani, Amita Gupta, Jyoti Mathad

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The oncolytic avian reovirus p17 protein suppresses invadopodia formation via disruption of TKs5 complexes and oncogenic signaling pathways by Chao-Yu Hsu, Jyun-Yi Li, Jyun-Yi Li, Wei-Ru Huang, Wei-Ru Huang, Tsai-Ling Liao, Tsai-Ling Liao, Hsiao-Wei Wen, Chi-Young Wang, Chi-Young Wang, Lon-Fye Lye, Brent L. Nielsen, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu

“…Furthermore, invadopodia detection, gelatin degradation assay, and Fluorescence imaging was performed to visualize invadopodia structures and assess extracellular matrix degradation. …”
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Preclinical Study of a Dual-Target Molecular Probe Labeled with ⁶⁸Ga Targeting SSTR2 and FAP by Huanhuan Liu, Xiaojun Zhang, Yue Pan, Jingfeng Zhang, Hui Wen, Cong Zhang, Xiaodan Xu, Guangyu Ma, Ruimin Wang, Jinming Zhang

“…It is an effective probe for non-invasive detection of tumors expressing FAP and SSTR2, and it is worth further studying its application in the expression of sstr2 and FAP-related tumors.…”
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Single intravenous administration of oncolytic adenovirus TILT-123 results in systemic tumor transduction and immune response in patients with advanced solid tumors by Elise Jirovec, Dafne C. A. Quixabeira, James H. A. Clubb, Santeri A. Pakola, Tatiana Kudling, Victor Arias, Lyna Haybout, Katriina Jalkanen, Tuomo Alanko, Tine Monberg, Amir Khammari, Brigitte Dreno, Inge Marie Svane, Matthew S. Block, Daniel A. Adamo, Johanna Mäenpää, Claudia Kistler, Suvi Sorsa, Otto Hemminki, Anna Kanerva, João M. Santos, Victor Cervera-Carrascon, Akseli Hemminki

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Modelling of circumferential surface topography of grinding wheel with random distribution of circular truncated cone abrasive grains by Xiaodong CHEN, Dexiang WANG, Feng GUO, Xinming LI, Jingliang JIANG

“…The model has high similarity to the distribution characteristics of real grinding wheel topography, and the grinding wheel surface forms irregular block-shaped and narrow strip-shaped gap areas. Therefore, this modeling method is suitable for the establishment of a corundum grinding wheel circumferential surface topography model. …”
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Review of observations on the boundary of the Martian induced magnetosphere by Jing Wang

“…The solar wind flow was blocked several hundred kilometers above the Martian ionosphere, forming a boundary known as the protonopause. …”
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ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels by Xuexue Liu, Xuexue Liu, Hongmei Deng, Zijuan Zhao, Shan Wen, Shan Wen, Kailong Ma, Xinyu Wang, Yanfei Du, Chang Li, Jun Li, Guangqin Zhang, Xiaobo Zhou, Tuck Wah Soong, Ziqi Yuan, Jian Feng, Guang Li

“…These changes not only prolonged PR-interval and blocked A-V conduction that triggered cardiac arrhythmia, but also led to a diminished calcium transient, which contributed to heart failure. …”
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Assessment of <i>ERBB2</i> and HER2 expression in metastatic breast cancer using the nCounter® system and a 100-gene scale by R.  M.  Paltuev, O.  A.  Volynshchikova, Sh.  R.  Abdullaeva, S.  N.  Aleksakhina, A.  S.  Artemyeva, E.  A.  Baychorov, S.  Yu.  Bakharev, Yu.  A.  Belaya, A.  A.  Bozhok, V.  A.  Vasin, V.  I.  Vladimirov, A.  Yu.  Vorontsov, E.  A.  Gaysina, A.  A.  Gofman, V.  N.  Dmitriev, E.  N.  Imyanitov, V.  V.  Klimenko, A.  V.  Komyakhov, M.  M.  Konstantinova, M. V.  Kopp, A.  G.  Kudaybergenova, I.  A.  Lalak, D.  L.  Matevosyan, N.  M.  Mudzhiri, O.  V.  Poltareva, O.  I.  Sevryukova, V.  F.  Semiglazov, T.  Yu.  Semiglazova, M.  M.  Urezkova, A.  S.  Chichkanova, L.  A.  Churilova, M.  V.  Shomova

“…We used the nCounter technology based on direct digital target detection using color-coded molecular barcodes. We analyzed the expression of 28 genes with a high predictive value for breast cancer.Results. …”
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Long-term effect of berberine in preventing recurrence of colorectal adenomas and neoplasms after endoscopic resection: 6-year-follow-up in a randomized, placebo-controlled, multic... by Yongjie Tan, Jingyuan Fang, Tianhui Zou, Ke Yu, Jian-Qiu Sheng, Peng Jin, Ming-Jie Zhang, Xiao-Ping Zou, Xiao-Tan Dou, Si-De Liu, Shao-Hui Huang, Jian-Lin Ren, Xiao-Ning Yang, Zhan-Ju Liu, Xiao-Min Sun, Bang-Mao Wang, Hai-Long Cao, Qin-Yan Gao, Hui-Min Chen, Yun Cui, Ying-Xuan Chen

“…Almost 90% of CRC cases develop from precursor adenomatous polyps, through a series of genetic changes known as adenoma-carcinoma sequence during at least 10 years. Detection and removal of colorectal adenoma (CRA) could reduce CRC mortality risk by colonoscopy, but the recurrence rate is high. …”
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Cloning and identification of human colipase-like 3 and its homologous cDNAs by LU Yan, XUE Yong-chang, YU Peng, WANG Ping-zhang

“…During our previous genome-wide analysis of single-block EST sequences with polyadenylation sites, we found a lot of ESTs that represented potentially novel un-identified genes or splice variants. …”
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AutoLDP: An accurate and efficient artificial intelligence-based tool for automatic labeling of digital pathology by Yingnan Zhao, Huifen Ye, Jing Yang, Su Yao, Maohua Lv, Zhihong Chen, Yunrui Ye, Qingru Hu, Cheng Lu, Zaiyi Liu, Ke Zhao, Zhihua Chen

“…We compared the proposed model with several commonly used text detection and recognition models including ABinet, CRNN, TRBA, and Vitstr. …”
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Jinxinkang granule alleviates chronic heart failure by enhancing GPER/AMPK/PCG-1α-mediated fatty acid oxidation by Haixiang Zhong, Liu He, Wanru Zhong, Lili Wang, Jianmin Luo, Qi Chen, Rong Li, Rong Zhang, Zhongqiu Liu, Yuanyuan Cheng

“…Cardiac function and morphology assessment using M-mode echocardiography, H&E/Masson/WGA staining, western blotting analysis, real-time PCR detection, ATP and cAMP assays were used to explore the mechanism of JXK against CHF. …”
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