High-Power, High-Repetition Short-Pulse Laser Driver Using Direct-Drive D-Mode GaN HEMT by Ching-Yao Liu, Chun-Hsiung Lin, Hao-Chung Kuo, Yu-Heng Hong, Edward-Yi Chang, Wei-Hua Chieng

“…In this work, an in-house D-mode GaN HEMT with a blocking voltage of 200 V and on-resistance of 18 mΩ is used in a short-pulse laser driver for the optical phased array (OPA) applications. …”
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Oxidative stress leads to the formation of esterified erythro- and threo-dihydroxy-fatty acids in HepG2 cells by Lilli Scholz, Luca M. Wende, Michel A. Chromik, Nadja Kampschulte, Nils Helge Schebb

“…Thus, the highest concentrations were found of erythro-5,6-DiHETrE and erythro-4,5-DiHDPE, which allowed a more sensitive detection of oxidative stress compared to 5-iPF2α-VI levels. …”
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Biomimetic Computing for Efficient Spoken Language Identification by Gaurav Kumar, Saurabh Bhardwaj

“…Multilingual countries utilize the SLID method to facilitate speech detection. This is accomplished by determining the language of the spoken parts using language recognizers. …”
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Securing IoT Against Slow-Rate DDoS Attacks: Implementation With Tofino P4 ASIC Hardware by Erick D. Ramirez-Martinez, Jesus A. Perez-Diaz, Noe M. Yungaicela-Naula, Sergio Armando Gutierrez, Christian Garzon

“…A decision tree model is deployed within a programmable switch (P4) to detect the attacks. Furthermore, an SDN controller is responsible for generating mitigation policies and deploying them to the programmable switches, effectively blocking malicious flows. …”
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ВЛИЯНИЕ ФУНКЦИ ПЕЧЕНИ НА ФАРМАКОКИНЕТИКУ β-БЛОКАТОРОВ У БОЛЬНЫХ С ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА И СОЧЕТАННОЙ ПАТОЛОГИЕЙ... by Л. С. Литвинова, С. В. Бабак, Е. В. Кириенкова, А. А. Корженков, Н. И. Самаров, О. Л. Носарева, Т. С. Прохоренко, Е. В. Коновалова, В. Д. Якушина, А. И. Дмитриева, Ю. В. Колобовникова, В. А. Серебрякова, С. П. Чумакова, А. Е. Неймарк, Н. Л. Карабицкая, А. Л. Хохлов, А. Е. Мирошников, Д. П. Комаров

“…The aim of our study is detection of the possible correlation between the degree of inflammation, fibrosis of the liver and the level plasma concentration of metoprolol in the treatment of chronic heart disease. …”
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Pseudoneutralizing test for preclinical studies of vaccines against SARS-CoV-2 by B. S. Cherepovich, A. M. Kudryashova, N. P. Kartashova, A. V. Gracheva, V. A. Manuilov, I. A. Leneva, O. V. Borisova, O. A. Svitich

“…In this study, 3 techniques were used for detection of antibodies to SARS-CoV-2 virus, as follows: 1) a pseudo-neutralizing test (PNT) to detect antibodies that block interaction between RBD and ACE-2; 2) neutralization test (RN) to detect virus-neutralizing antibodies, and 3) enzyme-linked immunosorbent assay to detect class G antibodies to RBD SARS-CoV-2. …”
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Performance and comparison of FLCCheck: a novel serum free light chain assay for the Auxiliary Diagnosis of Multiple Myeloma by Jinghao Cao, Xi Chen, Yu Zhou, Yajuan Lu, Aoli Deng, Sainan Li, Yuhan Chen, Jing Du, Jun Xia

“…Results The FLCCheck assay demonstrated a validated linear range, high precision, and strong resistance to interference for both κ and λ light chain detection. By incorporating blocking peptides to reduce cross-reactivity, we improved the reliability of the diluted recovery by more than twofold. …”
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Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus by Carlos Enrique Torres-Méndez, Sharmilee Nandi, Klara Martinovic, Patrizia Kühne, Yifan Liu, Sam Taylor, Maria Lysandrou, Maria Ines Berrojo Romeyro Mascarenhas, Viktoria Langwallner, Javier Enrique Sebastián Alonso, Ivana Jovanovic, Maike Lüftner, Georgia-Vasiliki Gkountana, David Bern, Abdul-Raouf Atif, Ehsan Manouchehri Doulabi, Gemma Mestres, Masood Kamali-Moghaddam

“…An electrochemical biosensor based on modified carbon screen-printed electrodes was developed for the detection of hemagglutinin of influenza A H1N1 virus (H1). …”
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Breadth and function of antibody response to acute SARS-CoV-2 infection in humans. by Kuan-Ying A Huang, Tiong Kit Tan, Ting-Hua Chen, Chung-Guei Huang, Ruth Harvey, Saira Hussain, Cheng-Pin Chen, Adam Harding, Javier Gilbert-Jaramillo, Xu Liu, Michael Knight, Lisa Schimanski, Shin-Ru Shih, Yi-Chun Lin, Chien-Yu Cheng, Shu-Hsing Cheng, Yhu-Chering Huang, Tzou-Yien Lin, Jia-Tsrong Jan, Che Ma, William James, Rodney S Daniels, John W McCauley, Pramila Rijal, Alain R Townsend

“…All ACE2-blocking anti-RBD antibodies were isolated from two recovered patients with prolonged fever, which is compatible with substantial ACE2-blocking response in their sera. …”
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Piezo1 Promotes Odontogenic Differentiation of Dental Pulp Stem Cells Under Stress Conditions by Xiaxia Wang, Shaojie Dong, Qianqian Dong, Xuefei Sun

“…The mechanotransduction of Piezo1 ion channels in DPSCs was determined by fluid shear stress (FSS) detection of calcium fluorescence intensity and whole-cell patch clamp detection. …”
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Imaging Monitoring Technology of Fractures Around Horizontal Wells with Multi-Stage Fracturing in Water Injection Development by ZHENG Gang, ZHU Hongzheng, LI Dajian, WANG Xu, TANG Xiangdong, SU Zubo

“…This technology employs a crawler to deploy a 3D far-field sonic imaging logging tool, allowing for the detection and recognition of fracture development around multi-stage fractured horizontal wells under waterflooding conditions. …”
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The role of SFRP1 in human dermal papilla cell growth and its potential molecular mechanisms as a target in regenerative therapy by Chaofan Wang, Yimei Du, Changpei Lu, Lingbo Bi, Yunbu Ding, Weixin Fan

“…Methods: In this study, DNA plasmids and siRNAs were constructed against the SFRP1 gene and transfected into DPCs cultured in vitro. We detected the viability, proliferation, and migration of DPCs by Calcein/PI fluorescence, CCK-8, trans-well, or cell scratch experiments, and the expression of potential target genes was also determined through quantitative detection of RNA and protein. …”
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MCP-1-CCR2-M2 macrophages axis contributes to diffuse large B-cell lymphoma progression and inhibits antitumor immune response by Zhao-Feng Wen, Qi-Tang Huang, Yang-Yang Wang, Feng-Ya Nan, Zhi-Min Zhai, Yan-Li Li

“…BALB/C mice subcutaneous tumors were evaluated and detected after blocking MCP-1/CCR2 axis with CCR2 antagonist. …”
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Suppressing Dark Counts of Multimode-Fiber-Coupled Superconducting Nanowire Single-Photon Detector by Chengjun Zhang, Weijun Zhang, Lixing You, Jia Huang, Hao Li, Xingqu Sun, Heqing Wang, Chaolin Lv, Hui Zhou, Xiaoyu Liu, Zhen Wang, Xiaoming Xie

“…The filter bench, which consists of lenses and optical filters, can provide a high transmittance of about 80% at the central wavelength of the passband (1550 ± 12.5 nm) and a wide blocking range from 500 nm to over 6000 nm at 40 K. …”
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A novel NKG2A alpaca nanobody targeting immune checkpoint blockade for the treatment of malignant melanoma by Xiang Guo, Xiang Guo, Xiang Guo, Congfang Guo, Dongxiao Li, Yuting Bai, Mureed Abbas, Mureed Abbas, Ruiwen Fan, Yiyan Zhao, Yiyan Zhao

“…This NKG2A-targeting nanobody demonstrates the potential for application in both the detection and treatment of MM.…”
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Orthoflavivirus circulation in South-East Queensland, Australia, before and during the 2021–2022 incursion of Japanese encephalitis virus assessed through sero-epidemiological surv... by Nicholas K.Y. Yuen, Jessica J. Harrison, Althea S.W. Wang, Isabella E. McMahon, Gervais Habarugira, Mitchell P. Coyle, Helle Bielefeldt-Ohmann

“…There was speculation that JEV may have been circulating in Australia unknowingly prior to the detection. In this study, we determined sero-prevalence and transmission of West Nile virus (WNV), Murray Valley encephalitis virus (MVEV) and JEV, prior to and post JEV incursion in a sentinel equine population in south-east Queensland (SEQ), Australia, using blocking ELISAs (screening test) and virus neutralisation test (confirmatory). …”
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Natural killer T cell immunotherapy combined with IL-15-expressing oncolytic virotherapy and PD-1 blockade mediates pancreatic tumor regression by Simon Gebremeskel, Adam Nelson, Brent Johnston, Brian D Lichty

“…This results from late detection, high rates of metastasis, and resistance to standard chemotherapies. …”
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From neglect to necessity: the role of innate immunity in cutaneous squamous cell carcinoma therapy by Yong He, Ting Tian, Yuancheng Li, Yong Zeng, Yong Zeng, Yong Zeng, Xiaoke Wang, Leqi Qian, Tian Tian, Mingjun Jiang, Liming Li, Liming Li

“…Cemiplimab, along with other immune checkpoint inhibitors, enhances T cell activation by blocking the PD-1 pathway, resulting in notable improvements in clinical outcomes. …”
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Impacts of coal fracture roughness and aperture on the seepage of injected water: An experimental study by Gang WANG, Xuechang CHEN, Hao CHEN, Qingming LONG, Yixin LIU

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Clinical characteristics and genetic profile of complement system in renal thrombotic microangiopathy in patients with severe forms of arterial hypertension by Mariam I. Akaeva, Natalia L. Kozlovskaya, Larisa A. Bobrova, Olga A. Vorobyeva, Ekaterina S. Stoliarevich, Petr A. Shatalov, Tatiana V. Smirnova, Anastasiia O. Anan'eva

“…Results. GD of CS were detected in a quarter of patients. Rare genetic variants classified as “likely pathogenic” including defects in CFI, C3, CD46, CFHR4, CFHR5 genes were detected in five cases. …”
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