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    Candida spp. colonization: a genotype source found in blood cultures that can become widespread by Aina Mesquida, Aina Mesquida, Pablo Martín-Rabadán, Pablo Martín-Rabadán, Luis Alcalá, Luis Alcalá, Almudena Burillo, Almudena Burillo, Elena Reigadas, Elena Reigadas, Patricia Muñoz, Patricia Muñoz, Patricia Muñoz, Patricia Muñoz, Jesús Guinea, Jesús Guinea, Jesús Guinea, Jesús Guinea, Pilar Escribano, Pilar Escribano, Pilar Escribano

    Published 2024-11-01
    “…The genotypes found were then compared with our in-house database containing 587 blood genotypes from patients admitted to the Gregorio Marañón Hospital (2007-2023) to assess the proportion of genotypes found in colonized samples that were also found in blood cultures. Moreover, since some of our in-house database genotypes had been tagged as widespread genotypes, we compared the proportions of widespread genotypes as well as the proportions of matches, clusters, and patients involved in clusters found among exclusively colonizing genotypes, exclusively blood culture genotypes, and both colonizing and blood culture genotypes using a standard binomial method.ResultsIntra-patient analysis was conducted exclusively on those patients (n=225; 69.7%) who had ≥2 isolates from a given species; the proportion of patients with matches was lower in exclusively colonized patients than in patients with candidemia and colonizing genotypes (87.3% vs. 94.1%; p = 0.126). …”
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