Comparison of the effectiveness of recombinant human growth hormone therapy in preterm and full-term children with short stature born small for gestational age by Dohyung Kim, Ji-Hee Yoon, Soojin Hwang, Ja Hye Kim, Han-Wook Yoo, Jin-Ho Choi

“…Serum insulin-like growth factor 1 and insulin-like growth factor binding protein 3 levels significantly increased after the start of rhGH therapy (P<0.001). …”
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Cinnamaldehyde ameliorates obesity-induced nephropathy in C57BL/6 mice via modulation of AMPK/ACC and NF-kB pathways by Himani Gupta, Uma Bhandari

“…In preclinical study, 4-week-old C57BL/6 mice (18–20 gm) were fed a conventional diet or HFD for 12 weeks After the fifth week of HFD intervention, mice were divided into six groups (n=10): vehicle group; HFD group; HFD+CA (20 mg/kg); HFD+CA (40 mg/kg); HFD+Orlistat (10 mg/kg); and CA Perse (40 mg/kg) treated orally for 49 days. …”
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Transmembrane Protein ANTXR1 Regulates γ-Globin Expression by Targeting the Wnt/β-Catenin Signaling Pathway by Tingting Jin, Zhaojun Zhang, Yuanyuan Han, Di Li, Juan Liu, Minmin Jiang, Junwei Zhu, Ryo Kurita, Yukio Nakamura, Fangfang Hu, Yongjie Xu, Xiangdong Fang, Shengwen Huang, Zhaolin Sun

“…Our findings may provide a new intervention target for the treatment of β-hemoglobinopathies.…”
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Quantification of the initial levels of calciprotein particles as a screening marker of mineral homeostasis in patients with cardiovascular disease and in patients with chronic kid... by D. K. Shishkova, V. G. Matveeva, V. E. Markova, O. N. Khryachkova, E. V. Indukaeva, А. R. Shabaev, A. V. Frolov, A. G. Kutikhin

“…In combination with elevated ionized calcium and reduced albumin, this suggests the depletion of calcium binding buffers in the serum of patients with cardiovascular and renal diseases.…”
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Modulation of hormonal, metabolic, inflammatory and oxidative stress biomarkers in women with polycystic ovary syndrome following combined (resistant and endurance) training: a ran... by Masoud Nasiri, Amirabbas Monazzami, Solmaz Alavimilani, Zatollah Asemi

“…At the baseline and end-of-intervention, metabolic profiles including fasting plasma glucose, insulin, homeostatic model assessment for insulin resistance (HOMA-IR), quantitative insulin sensitivity check index (QUICKI), lipid profiles, testosterone, free androgen index (FAI), sex hormone binding globulin, anti-Müllerian hormone, malondialdehyde, total antioxidant capacity, and high Sensitive-C reactive protein were evaluated. …”
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Somatic mutations and DNA methylation identify a subgroup of poor prognosis within lower‐risk myelodysplastic syndromes by David Rombaut, Sarah Sandmann, Tobias Tekath, Simon Crouch, Aniek O. deGraaf, Alexandra Smith, Daniel Painter, Olivier Kosmider, Magnus Tobiasson, Andreas Lennartsson, Bert A. van derReijden, Sophie Park, Maud D'Aveni, Borhane Slama, Emmanuelle Clappier, Pierre Fenaux, Lionel Adès, Arjan van deLoosdrecht, Saskia Langemeijer, Argiris Symeonidis, Jaroslav Čermák, Claude Preudhomme, Aleksandar Savic, Ulrich Germing, Reinhard Stauder, David Bowen, Corine vanMarrewijk, Elsa Bernard, Theo deWitte, Julian Varghese, Eva Hellström‐Lindberg, Martin Dugas, Joost Martens, Luca Malcovati, Joop H. Jansen, Michaela Fontenay, MDS‐RIGHT consortium

“…All clusters shared hypermethylated enhancers enriched in binding motifs for ETS and bZIP (C/EBP) transcription factor families, involved in the regulation of myeloid cell differentiation. …”
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Cytokines and autologic bone marrow mononuclears in postmyocardial infarction regeneration by V. V. Ryabov, V. A. Markov, Yu. S. Poponina, T. E. Suslova, A. L. Krylov, S. V. Popov, R. S. Karpov

“…This open, randomized, controlled study included 44 AMI patients: 22 in intervention group (I) and 22 in control group (II). …”
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Baicalein Alleviates Lithium-Pilocarpine-Induced Status Epilepticus by Regulating DNMT1/GABRD Pathway in Rats by Zhenggang Wu, Jing Liu, Deju Yin, Jing Huang, Yujing Huang, Pengfei Wang

“…The rats were divided into control group, epileptic SE group and baicalein intervention group. Morris water maze (MWM) test, Nissl staining, immunofluorescence and enzyme-linked immunosorbent assay (ELISA) were used to detect cognitive functions and neuronal damage. …”
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Price discovery and market efficiency of cardamom in India by A.N. Vijayakumar

“…Hence, suggests policy intervention for implementing an online Forward Market mechanism for Indian cardamom to ensure market efficiency and manage price risk.…”
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Neurovascular Restoration by Treadmill Exercise Attenuates Age-Related Cognitive Decline in Mice by Jae Min Lee, Da-Eun Sung, You Jung Choi, Seung Geun Yeo, Youn-Jung Kim

“…Activation of microglia and astrocytes was determined by analyzing the expression of ionized calcium-binding adapter molecule 1 and glial fibrillary acidic protein through immunohistochemistry and immunofluorescence. …”
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YAP as a potential therapeutic target for myofibroblast formation in asthma by Yanrong Guo, Yuran Zhou, Rui Wang, Yujing Lin, Huimin Lan, Yang Li, De-Yun Wang, Jinrui Dong, Kefeng Li, Yan Yan, Yongkang Qiao

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NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing by Nan Meng, Lingjun Li, Xueqin Yang, Hui Tang, Jizhong Wang, Songbai Zhang, Zongbao Xia, Jia Yao, Qi Zhang, Changrong Hu, Chunjie Su, Rui Duan

“…In conclusion, NXF1 suppresses ECa tumorigenicity and progression through an SRSF3-mediated SP4 alternative splicing mechanism, and could serve as a novel prognostic biomarker for clinical intervention in ECa.…”
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Deciphering the pharmacological mechanism of Radix astragali for allergic rhinitis through network pharmacology and experimental validation by Yiwei Hua, Xi Tan, Jingwen Zhang, Ningcong Xu, Ruien Chen, Shiqing Zhou, Shaoqing Liu, Kai Li, Wenyong Chen, Qiulan Luo, Yunying Li

“…Molecular docking and dynamics simulations confirmed the strong binding affinity and stability of RA’s phytochemicals to these targets. …”
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Comparison of antigen-specific B cell responses reveals disparity in immunogenicity and memory B cell formation across COVID-19 vaccine platforms by Chang Guo, Xin Chai, Maidaiti Baerlike, Yingping Liu, Yao Wang, Fei Shao, Qingrui Huang, Weiguo Zhang, Shan Cen, Yijie Dong, Yunlong Cao, Jinghua Yan, Xuyu Zhou, Zhaolin Hua, Baidong Hou

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Optimization of the formula for the compound ointment of Polygonatum sibiricum and lotus leaf and its modulation on hepatic lipid metabolism of high-fat diet rats(黄精荷叶复合膏配方优化及对高脂膳食... by 严晓雪(YAN Xiaoxue), 田湘珺(TIAN Xiangjun), 周溯(ZHOU Su), 郑跃妍(ZHENG Yueyan), 蒋益虹(JIANG Yihong)

“…Moreover, a high dose of the compound ointment significantly reduced the mRNA levels of sterol-regulatory element binding protein-1c gene (SREBP-1c) and acetyl-CoA carboxylase α gene (ACC-α) and increased the mRNA level of carnitine palmitoyl transferase-1 gene (CPT-1). …”
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<i>Bacillus</i><i> thuringiensis</i> Exopolysaccharide BPS-2 Ameliorates Ulcerative Colitis in a Murine Model Through Modulation of Gut Microbiota and Suppression of the NF-κB Casc... by Zexin Gao, Huan Li, Jungang Wen, Wenping Ding, Jie Yu, Yue Zhang, Xiaojuan Song, Jianrong Wu

“…These findings establish BPS-2 as a natural food additive that modulates the microbiota-barrier–inflammation axis through dietary intervention, offering a novel strategy to alleviate UC.…”
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Baicalin targets YTHDC2 and alleviates male reproductive toxicity caused by co-exposure to nanoplastics and manganese through m6A-dependent pathway by Yi Wen, Tingwei Pan, Lu Liu, Jinning Wang, Kexin Yang, Zhushan Fu, Wenhao Li, XinMiao Wang, Zhiru Shen, Yan Li, Yinke Du, Yu Deng

“…Mechanistically, PS-NPs and Mn collaboratively suppress the RNA-binding protein YTHDC2, which in turn impairs Mdm2 transcription and translation in an m6A-dependent manner. …”
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Periorbital Oedema as a Crucial Diagnostic Clue for Systemic Lupus Erythematosus in a Young Woman: A Case Report by Madhulika L Mahashabde, Jugal Sriram, Gaurav Choudhary, Sai Krishna Reddy Paidi, Rishikesh Sunilsingh Chauhan

“…Prompt recognition and early diagnosis, along with timely intervention, can improve outcomes for patients with this complex autoimmune disease. …”
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Plant Compounds Inhibit the Growth of W12 Cervical Precancer Cells Containing Episomal or Integrant HPV DNA; Tanshinone IIA Synergizes with Curcumin in Cervical Cancer Cells by Linda Saxe Einbond, Jing Zhou, Kunhui Huang, Mario R. Castellanos, Emeka Mbazor, Michael Balick, Hongbao Ma, James A. DeVoti, Stephen Redenti, Hsan-au Wu

“…Molecular docking studies suggested tanshinone IIA and curcumin bind to the Na⁺/K⁺-ATPase ion channel, with curcumin binding with higher affinity. …”
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The impact of aberrant lipid metabolism on the immune microenvironment of gastric cancer: a mini review by Shuangyu Chen, Wenqian Chen, Tinghui Xu, Jiayang Li, Jianghao Yu, Yibo He, Shengliang Qiu

“…Integrating metabolic intervention with immunotherapy holds potential to overcome current treatment limitations and improve clinical outcomes. …”
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