Continuous requirement for the Clr4 complex but not RNAi for centromeric heterochromatin assembly in fission yeast harboring a disrupted RITS complex. by Sreenath Shanker, Godwin Job, Olivia L George, Kevin M Creamer, Alaa Shaban, Janet F Partridge

“…The RITS complex physically links Ago1 and the H3-K9me binding protein Chp1. Here we exploit an assay for heterochromatin assembly in which loss of silencing by deletion of RNAi or Clr-C components can be reversed by re-introduction of the deleted gene. …”
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Whole genome sequencing of an African American family highlights toll like receptor 6 variants in Kawasaki disease susceptibility. by Jihoon Kim, Chisato Shimizu, Stephen F Kingsmore, Stephen F Kingsmore, Narayanan Veeraraghavan, Eric Levy, Andre M Ribeiro Dos Santos, Hai Yang, Jay Flatley, Long Truong Hoang, Martin L Hibberd, Adriana H Tremoulet, Olivier Harismendy, Lucila Ohno-Machado, Jane C Burns

“…TLR6 plays an important role in pathogen-associated molecular pattern recognition, and sequence variations may affect binding affinities that in turn influence KD susceptibility. …”
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Genome-Wide Identification of Cucumber <i>Lhc</i> Genes’ Family and Their Expression Analysis by Yongmei Miao, Kaijing Zhang

“…Light-harvesting chlorophyll a/b-binding (Lhc) proteins are integral membrane proteins that bind to pigment molecules, playing a critical role in photosynthetic processes, including light energy harvesting and transfer. …”
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The diagnostic and therapeutic potential of miR-3149 in osteoporotic fractures through SMAD4 by Guanwei Xu, Zhichao Yang, Sibao Zeng, Yongqi Dong, Lina Huang

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Beyond Stress Granules: G3BP1 and G3BP2 Redundantly Suppress SARS-CoV-2 Infection by Duo Xu, Mahamaya Biswal, Quanqing Zhang, Christine Light, Yijie Wu, Chenjin Ye, Luis Martínez-Sobrido, Jikui Song, Rong Hai

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Genome-wide uH2A localization analysis highlights Bmi1-dependent deposition of the mark at repressed genes. by Eric M Kallin, Ru Cao, Raja Jothi, Kai Xia, Kairong Cui, Keji Zhao, Yi Zhang

“…Although recent studies have revealed the genome-wide binding patterns of some of the PRC1 and PRC2 components, as well as the H3K27me3 mark, there have been no reports describing genome-wide localization of uH2A. …”
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Development of an encapsulation process for toxic waste and hazardous chemicals in a fluidized bed by Yu. A. Eleev, Yu. S. Bogoyavlenskaya, E. N. Glukhan, V. F. Golovkov, V. V. Afanasiev

“…The results demonstrate that the mechanism for granule formation is a mixed mechanism. The binding of the seed material is carried out by both the pitch and salting out. …”
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By modulating miR‐525‐5p/Bax axis, LINC00659 promotes vascular endothelial cell apoptosis by Xizheng Zhu, Beijia Chen, Hui Xu

“…Endothelial cells play a crucial role in the processes vasoconstriction, platelet activation, and blood coagulation and are an integral part of the vascular response to injury resulting in thrombus formation. …”
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Exploring the association between osteoporosis and kidney stones: a clinical to mechanistic translational study based on big data and bioinformatics by Di Luo, Linguo Xie, Jingdong Zhang, Chunyu Liu

“…Gene expression data from the Gene Expression Omnibus (GEO) microarray database were integrated with machine learning techniques to identify key genes involved in both osteoporosis and kidney stones. …”
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ISLR as a Cuproptosis-Related Predictor and Therapeutic Target in Heart Failure: A Multi-Omics and Bioinformatics Approach by Huang K, Ding S, Xu X, Wang C, Han L

“…CTD database and molecular docking were applied to seek for the chemicals binding to the selected gene.Results: In the study, it was found that a total of 21 CRGs exhibited dysregulated expression in individuals with heart failure (HF). …”
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Neurovascular Restoration by Treadmill Exercise Attenuates Age-Related Cognitive Decline in Mice by Jae Min Lee, Da-Eun Sung, You Jung Choi, Seung Geun Yeo, Youn-Jung Kim

“…Furthermore, treadmill exercise preserved BBB integrity by maintaining the expression of tight junction proteins and PDGFRβ, counteracting age-related declines. …”
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CzcR-dependent reduction of catalase gene expression and induction of catalase activity in Pseudomonas aeruginosa during zinc excess by Ting Li, Zhifeng Mo, Yuying Zhao, Huiluo Cao, Shuo Sheng, Zeling Xu

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Effect of the TLR9 signaling pathway on acyclovir infection with herpes simplex virus type 2 in HaCaT cells by Jialing Shi, Lin Kuang, Li Qi, Ruoyu Li, Yangfan Wu

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Tip optofluidic immunoassay: Evaluating COVID-19 antibody protection with 1 μL fingertip blood by Xiaotian Tan, Yujuan Chai, Ruihan Li, Binmao Zhang, Hao Li, Jie Zhang, Tianen Zhu, Weishu Wu, Lixiang An, Shi Hu, Bin Yang, Li Wang, Zhenqiu Cao, Hongjiu Zhang, Peng Wang, Lingling Yu, Shan Yin, Xingyu Li, Fei Shao, Jianheng Huang, Jinze Li, Fan Yang, Chao Zhao, Jiajia Guo, Lin Zeng, Dong Liang, Zhengting Zou, Hairong Zheng, Xudong Fan, Liangzhi Xie, Yunlong Cao, Hui Yang

“…This study presents a custom-developed tip optofluidic immunoassay (TOI) platform that enables rapid, multiplexed antibody profiling using only 1 μL of fingertip blood. The system integrates batch-fabricated microfluidic immunoreactors with a portable chemiluminescent imaging station, completing both binding and neutralization capability assessments within 40 min. …”
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Effect of Ca2+ on the structure of collagen fibers in sea cucumber (Apostichopus japonicus) under low-temperature tenderization condition by Chen Zhang, Wei Wang, Hongyan Li, Hongxia Che, Wancui Xie, Wenming Ju, Hang Qi, Xiufang Dong

“…FTIR, XRD, DSC, TGA and SEM analyses revealed that low concentrations of Ca2+ (2.5 and 5 mM) increased the intermolecular binding of CFs, enhanced stability of triple helix structure, maintained the structural integrity of CFs, and inhibited the degradation of CFs. …”
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Portable 3D-Printed Paper Microfluidic System with a Smartphone Reader for Fast and Reliable Copper Ion Monitoring by Jingzhen Cao, Nan Cheng, Zhengyang Liu, Qian Lu, Lei Li, Yuehe Lin, Xian Zhang, Dan Du

“…In this study, we develop a sensitive multi-channel paper microfluidic device integrated with a 3D-printed smartphone-based colorimetric reader for the rapid detection of Cu²⁺. …”
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Regulatory culture and architectural project by Mario Losasso

“…Hence, it oscillates between binding prescription and non-binding information levels or recommendations. …”
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NXT2 is a key component of the RNA nuclear export factor complex in the human testis and essential for spermatogenesis by Ann-Kristin Dicke, Ammar Ahmedani, Lin Ma, Leonie Herrmann, Godfried W. van der Heijden, Sophie A. Koser, Claudia Krallmann, Oguzhan Kalyon, Miguel J. Xavier, Joris A. Veltman, Sabine Kliesch, Nina Neuhaus, Noora Kotaja, Frank Tüttelmann, Birgit Stallmeyer

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Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide by Zhi-Xue Xu, Qiang Zhang, Gong-Li Ma, Cong-Heng Chen, Yan-Ming He, Li-Hui Xu, Yuan Zhang, Guang-Rong Zhou, Zhen-Hua Li, Hong-Jie Yang, Ping Zhou

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Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease by Tuukka Helin, Mari Palviainen, Marja Lemponen, Katariina Maaninka, Pia Siljander, Lotta Joutsi-Korhonen

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