Staphylococcus aureus cell wall structure and dynamics during host-pathogen interaction. by Joshua A F Sutton, Oliver T Carnell, Lucia Lafage, Joe Gray, Jacob Biboy, Josie F Gibson, Eric J G Pollitt, Simone C Tazoll, William Turnbull, Natalia H Hajdamowicz, Bartłomiej Salamaga, Grace R Pidwill, Alison M Condliffe, Stephen A Renshaw, Waldemar Vollmer, Simon J Foster

“…Peptidoglycan is the major structural component of the Staphylococcus aureus cell wall, in which it maintains cellular integrity, is the interface with the host, and its synthesis is targeted by some of the most crucial antibiotics developed. …”
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Synthesis, characterization and bio-evaluation of novel series of pyrazoline derivatives as potential antifungal agents by Chandra Shekhar Yadav, Atul Krishna, Suriya Pratap Singh, Jai Kishan, Sidharth Chopra, Kajal Srivastava, Rajdeep Guha, Minaxi B. Lohani, Varish Ahmad, Anwar A. Alghamdi, Abdul Rahman Khan, Iqbal Azad

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Vitamin C exerts anti-cadmium induced fracture functions/targets: bioinformatic and biostructural findings by Rong Li, Songzuo Yu, Xiao Liang, Yu Li, Keng Po Lai

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Asxl1 regulates optic cup development through interaction with Lhx2 and epigenetic modulation of Wnt signaling by Seungtae Moon, Nackhyuong Kim, A-Reum Kim, Kyeong Hwan Moon, Jin Woo Kim, Soo-Jong Um

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Pyrroloquinoline Quinone Improved Boar Sperm Quality via Maintaining Mitochondrial Function During Cryopreservation by Shanpeng Wang, Qi Wang, Lingjiang Min, Hailiang Cao, Adedeji O. Adetunji, Kaifeng Zhou, Zhendong Zhu

“…After freezing–thawing, the sperm motility, viability, acrosome integrity, mitochondrial activity, adenosine triphosphate (ATP) levels, DNA integrity, malondialdehyde (MDA) levels, reactive oxygen species (ROS) levels, superoxide dismutase (SOD) activity, mitochondrial transcription proteins levels, and fertilization capacity were assessed. …”
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Redundant microtubule crosslinkers prevent meiotic spindle bending to ensure diploid offspring in C. elegans. by Wenzhe Li, Helena A Crellin, Dhanya Cheerambathur, Francis J McNally

“…Depletion of ZYG-8, a doublecortin-related microtubule binding protein, led to slower anaphase B spindle elongation. …”
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Nephroprotective effects of Rhodomyrtus tomentosa in 7,12-Dimethylbenz[a]anthracene (DMBA)-Induced Nephrotoxicity: Computational and physiological analysis of cytokine expression by Putri Cahaya Situmorang, Syahputra Wibowo, Reka Mustika Sari, Alexander Patera Nugraha, Alek Ibrahim, Alfia Fitrianita, Naufal Abiyyu, Syafruddin Ilyas, Rony Abdi Syahputra

“…This study uniquely integrates in silico and in vivo approaches to evaluate the nephroprotective potential of Rhodomyrtus tomentosa (haramonting), addressing a critical gap in current literature. …”
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Molecular Characterization of Propolis-Resistant <i>Saccharomyces cerevisiae</i> Obtained by Evolutionary Engineering by Filiz Demir-Yılmaz, Mevlüt Arslan, Can Holyavkin, Alican Topaloğlu, Halil İbrahim Kısakesen, Yusuf Sürmeli, Zeynep Petek Çakar

“…Moreover, it had significantly lower reactive oxygen species levels and higher cell wall integrity than the reference strain. Comparative transcriptomic analysis results revealed that the genes involved in oxidoreductase activity, transmembrane transporter activity, unfolded protein binding and pleiotropic drug resistance were upregulated in FD11. …”
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Current-Volt Biosensing “Cystatin C” on Carbon Nanowired Interdigitated Electrode Surface: A Clinical Marker Analysis for Bulged Aorta by Xi Chen, Jie Kang, Qiu Sun, Cheng Liu, Hongling Wang, Chen Wang, Subash C. B. Gopinath

“…Papain was immobilized through the covalent integration of amine group on papain and the carboxyl group with carbon nanowire. …”
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Structural stability of Calmodulin-target peptide complex at different temperatures based on molecular dynamics simulation by Jiayi Ding, Zhaoyang Ju, Tengfei Fu, Liyong Ding, Xinyi Yan, Bing Zhou, Mengting Yu, Chengsheng Ge

“…Abstract Calmodulin (CaM) is a multifunctional protein commonly found in various eukaryotic cells that can bind Ca2+, making it highly valuable for research in agriculture, medicine, the environment, and other fields. …”
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Targeting Trefoil Factor Family 3 in Obstructive Airway Diseases: A Computational Approach to Novel Therapeutics by Alireza Shahriary, Mohsen Sisakht, Masoud Arabfard, Esmaeil Behmard, Ali Najafi

“…Gene expression analysis utilized Z-scores from the Library of Integrated Network-Based Cellular Signatures (LINCS) database to identify compounds altering TFF3 expression. …”
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Identification of bioactive compounds and molecular targets of Fuke Huahuang formulation to treat vaginitis by Huiyu Liu, Jie Mo, Cheng Liang, Qingting Chen, Bin Yang, Jiaqi Liu

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Evaluation of performance and matrix compatibility of mixed mode C18-SCX SPME fibers for compounds with different physicochemical properties by Marcos Tascon, Ezel Boyaci, Nathaly Reyes-Garcés, Janusz Pawliszyn

“…Fiber reusability was validated over three consecutive extractions (RSD ≤ 10 %), and morphological integrity was preserved post-extraction, even in challenging matrices like whole blood. …”
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Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing. by Jeong-Hyeon Choi, Yajun Li, Juyuan Guo, Lirong Pei, Tibor A Rauch, Robin S Kramer, Simone L Macmil, Graham B Wiley, Lynda B Bennett, Jennifer L Schnabel, Kristen H Taylor, Sun Kim, Dong Xu, Arun Sreekumar, Gerd P Pfeifer, Bruce A Roe, Charles W Caldwell, Kapil N Bhalla, Huidong Shi

“…The methylated DNA fragments were enriched with methyl-binding proteins, treated with bisulfite, and sequenced using the Roche-454 GS FLX sequencer. …”
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Methionine cycle in C. elegans serotonergic neurons regulates diet-dependent behaviour and longevity through neuron-gut signaling by Sabnam Sahin Rahman, Shreya Bhattacharjee, Simran Motwani, Govind Prakash, Rajat Ujjainiya, Shivani Chitkara, Tripti Nair, Rachamadugu Sai Keerthana, Shantanu Sengupta, Arnab Mukhopadhyay

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Coordinated cpSRP43 and cpSRP54 Abundance Is Essential for Tetrapyrrole Biosynthesis While cpSRP43 Is Independent of Retrograde Signaling by Shuiling Ji, Huijiao Yao, Bernhard Grimm

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Unraveling the SOX11-IGF2 signaling axis in early lung development: implications for lung disease by Jing Zhang, Xiaoyue Sun, Jingyi Lai, Liyan Wang, Feifei Li, Chunwei Cao

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MRDDA: a multi-relational graph neural network for drug–disease association prediction by Congzhou Chen, Yaozheng Zhou, Yinghong Li, Jin Xu, Demin Li, Lingfeng Wang

“…Additionally, molecular docking experiments reinforced our results by confirming the binding affinities and interactions between selected drugs and their target diseases, suggesting a solid basis for further experimental studies. …”
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Cultural interplay in end-of-life care decisions: comparing advance directive beliefs and preferences among adults in the U.S. and Taiwan by Duan-Rung Chen, Yuchi Young, Ashley Shayya, Taylor Perre, Thomas O’Grady

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Effect of carboxymethyl cellulose and/or wheat gluten on the pasting, rheological and quality properties of wheat starch-based batter for deep-fried products by Ying Xu, Ruishu Zhang, Kangyu Wang, Prince Chisoro, Feng Huang, Jing Wang, Chunhui Zhang

“…The microstructure suggested that the addition of WG-CMC increased the density and integrity of the gel network. Overall, CMC competed for the binding sites of WG on WS, reducing the increase in viscoelasticity caused by the interaction between WG and WS. …”
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