Fungal virulence and development is regulated by alternative pre-mRNA 3'end processing in Magnaporthe oryzae. by Marina Franceschetti, Emilio Bueno, Richard A Wilson, Sara L Tucker, Concepción Gómez-Mena, Grant Calder, Ane Sesma

“…RNA-binding proteins play a central role in post-transcriptional mechanisms that control gene expression. …”
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A functional screen uncovers circular RNAs regulating excitatory synaptogenesis in hippocampal neurons by Darren Kelly, Silvia Bicker, Jochen Winterer, Prakruti Nanda, Pierre-Luc Germain, Christoph Dieterich, Gerhard Schratt

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Using Cholesterol-Loaded Cyclodextrin to Improve Cryo-Survivability and Reduce Capacitation-Like Changes in Gender-Ablated Jersey Semen by Ahmed S. Aly, Kevin J. Rozeboom, John J. Parrish

“…In conclusion, CLC addition significantly improved gender-ablated post-thaw sperm viability, acrosome integrity, and fertilizing ability while preserving motility, capacitation progress, and binding ability to oviduct cells.…”
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Flow cytometry for the analysis of α-dystroglycan glycosylation in fibroblasts from patients with dystroglycanopathies. by Elizabeth Stevens, Silvia Torelli, Lucy Feng, Rahul Phadke, Maggie C Walter, Peter Schneiderat, Ayad Eddaoudi, Caroline A Sewry, Francesco Muntoni

“…α-dystroglycan (α-DG) is a peripheral membrane protein that is an integral component of the dystrophin-glycoprotein complex. …”
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m6A RNA methylation-mediated control of global APC expression is required for local translation of β-actin and axon development by Loic Broix, Rohini Roy, Belal Shohayeb, Ikumi Oomoto, Hiroki Umeshima, Dan Ohtan Wang

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Computational identification of novel natural inhibitors against triple mutant DNA gyrase A in fluoroquinolone-resistant Salmonella Typhimurium by Sree Haryini, George Priya Doss C

“…The structural stability and integrity of the modeled protein were ensured through rigorous validation. …”
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Cohesin stabilization at promoters and enhancers by common transcription factors and chromatin regulators by Audra F. Bryan, Megan Justice, Alexis V. Stutzman, Daniel J. McKay, Jill M. Dowen

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Structure based in silico screening of natural Vitamin D analogs for targeted and safer treatment of resistant multiple sclerosis by Mohtashim Lohani, Nizar Ahmad Khamjan, Sajad Ahmad Dar, Farrukh Aqil, Saif Khan, Arshad Jawed, Saba Beigh, Taru Singh, Iffat Zareen Ahmad

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Targeting necroptosis in MCF-7 breast cancer cells: In Silico insights into 8,12-dimethoxysanguinarine from Eomecon Chionantha through molecular docking, dynamics, DFT, and MEP stu... by Maram B Alhawarri, Mohammad G Al-Thiabat, Amit Dubey, Aisha Tufail, Katreen Banisalman, Ghazi A Al Jabal, Eman Alkasasbeh, Esra'a Ibrahim Al-Trad, Bilal Harieth Alrimawi

“…MM-PBSA revealed the enhanced binding efficacy of SG-A, with a significant binding free energy of -31.03 ± 0.16 kcal/mol against MLKL, surpassing that of the control (23.96 ± 0.11 kcal/mol). …”
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MHCI trafficking signal‐based mRNA vaccines strengthening immune protection against RNA viruses by Yupei Zhang, Songhui Zhai, Shugang Qin, Yuting Chen, Kepan Chen, Zhiying Huang, Xing Lan, Yaoyao Luo, Guohong Li, Hao Li, Xi He, Meiwan Chen, Zhongwei Zhang, Xingchen Peng, Xin Jiang, Hai Huang, Xiangrong Song

“…This approach involved the integration of MITD into the mRNA sequence encoding the virus antigen. …”
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Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology by Isaac Karimi, Layth Jasim Mohammad, A. Suvitha, Zohreh Haidari, Helgi B. Schiöth

“…Low volume distributions of all CPAs except glucose indicate high water solubility or high protein binding because higher amounts of the CPAs remain in the seminal plasma.ConclusionADMET information of the CPAs and extenders in the bipartite compartments of seminal plasma and intracellular spaces of spermatozoa are very important for systematic definition and integration because the nature of the extenders and seminal plasma could alter the physiology of cryopreserved spermatozoa.…”
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A compilation pipeline for wildlife tracking datasets collected from ground-based and satellite-based telemetry transmission devices by Gregory T. Wann, Ashley L. Whipple, Michael S. O'Donnell, Cameron L. Aldridge

“…Wildlife conservation planning increasingly requires collaboration and integration of research from discrete studies spanning large geographic areas. …”
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Genetics and clinical implications of SPINK1 in the pancreatitis continuum and pancreatic cancer by Qi-Wen Wang, Wen-Bin Zou, Emmanuelle Masson, Claude Férec, Zhuan Liao, Jian-Min Chen

“…We emphasize the integration of a full-length gene splicing assay (FLGSA) with SpliceAI’s predictive capabilities, establishing SPINK1 the first disease gene for which the splicing impact of all possible coding variants was prospectively determined. …”
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S100A11 as an immune-related exosomal driver of colorectal cancer progression: a novel diagnostic biomarker by Haibo Wang, Rongchao He, Deng Liu, Jun He, Zhong Shen

“…The integration of bioinformatics, machine learning, and experimental validation underscores the potential of exosome-derived markers for immunotherapy and precision oncology. …”
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Closed-Loop Valorization of Annatto Seed Waste into Biochar: A Sustainable Platform for Phosphorus Adsorption and Safe Nutrient Recycling in Agro-Industries by Diana Guaya, Camilo Piedra, Inmaculada Carmona

“…Although the material showed limited reusability, it holds potential for integration into nutrient recycling strategies as a slow-release fertilizer. …”
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Maternal PRDM10 activates essential genes for oocyte-to-embryo transition by Michelle K. Y. Seah, Brenda Y. Han, Yan Huang, Louise J. H. Rasmussen, Andrina J. Stäubli, Judith Bello-Rodríguez, Andrew Chi-Ho Chan, Maxime Gasnier, Heike Wollmann, Ernesto Guccione, Daniel M. Messerschmidt

“…Transcriptomic analysis and integration of genome-wide chromatin-binding data reveals new and essential PRDM10 targets, including the cytoskeletal protein encoding gene Septin11. …”
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Price discovery and market efficiency of cardamom in India by A.N. Vijayakumar

“…Design/methodology/approach – This study used Johansen co-integration, vector error correction model, Granger causality and regression with dummy variables to understand a day of the week effect in high-value agri-commodity of cardamom e-auction prices. …”
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Delta-catenin is required for cell proliferation in virus-positive Merkel cell carcinoma cell lines but not in human fibroblasts by Joselyn Landazuri Vinueza, Nicholas J. H. Salisbury, Kristine N. Dye, Ann Roman, Denise A. Galloway

“…ABSTRACT Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer often driven by the integration of Merkel cell polyomavirus (MCPyV) into the host genome and the persistent expression of its viral oncoproteins, small tumor (ST) antigen, and truncated large tumor (t-LT) antigen. …”
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Proximity‐dependent biotinylation reveals an interaction between ubiquitin‐specific peptidase 46 and centrosome‐related proteins by Kazuma Yoshioka, Reiko Nakagawa, Chi Lieu Kim Nguyen, Hayate Suzuki, Kiyohiro Ishigaki, Seiya Mizuno, Tsukasa Okiyoneda, Shizufumi Ebihara, Kazuya Murata

“…Using homology‐independent targeted integration (HITI), a genome editing technique, we established knockin cell lines that stably express USP46 wildtype‐ or ΔK92‐biotin ligase fusion protein. …”
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Nanoparticle-mediated gene delivery techniques in plant systems by Kuber Shivashakarappa, Sureshbabu Marriboina, Korsi Dumenyo, Ali Taheri, Zeinab Yadegari

“…Nanoparticles are well recognized for its flexible size, shape, and cargo-binding properties, which enable them to surpass defensive primary cell wall barrier and it can be a promising candidate for plant gene delivery applications. …”
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