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  1. 741
  2. 742

    Principles of Medical Biochemistry / by Meisenberg, Gerhard

    Published 2017
    Table of Contents: “…Introduction to biomolecules -- Introduction to protein structure -- Oxygen-binding proteins : hemoglobin and myoglobin -- Enzymatic reactions -- Coenzymes -- DNA, RNA, and protein synthesis -- The human genome -- Protein targeting and proteostasis -- Introduction to genetic diseases -- Viruses -- DNA technology -- Biological membranes -- The cytoskeleton -- The extracellular matrix -- Extracellular messengers -- Intracellular messengers -- Plasma proteins -- Defense mechanisms -- Cellular growth control and cancer -- Digestive enzymes -- Introduction to metabolic pathways -- Glycolysis, tricarboxylic acid cycle, and oxidative phosphorylation -- Oxygen deficiency and oxygen toxicity -- Carbohydrate metabolism -- The metabolism of fatty acids and triglycerides -- The metabolism of membrane lipids -- Lipid transport -- Amino acid metabolism -- Metabolism of iron and heme -- The metabolism of purines and pyrimidines -- Micronutrients -- Integration of metabolism.…”
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  3. 743

    Sensing the Stiffness: Cellular Mechano-Sensing at the Implant Interface by Patricia S. Pardo, Delia Danila, Raja Devesh Kumar Misra, Aladin M. Boriek

    Published 2025-07-01
    “…In this perspective, we highlight the relevance of the FA-Hippo signaling pathway and its regulation of the Yes-associated protein (YAP) and the transcriptional coactivator with a PDZ-binding domain (TAZ) as main players in the process of implants integration. …”
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    Article
  4. 744

    Altered sense of agency in schizophrenia: the aberrant effect of cardiac interoceptive signals by Akihiro Koreki, Akihiro Koreki, Akihiro Koreki, Yuri Terasawa, Atsuo Nuruki, Hiroki Oi, Hugo Critchley, Mahinda Yogarajah, Mitsumoto Onaya

    Published 2024-09-01
    “…The effect of cardiac interoceptive signals on SoA was measured by the difference in intentional binding effect during systole and diastole. This measure was standardized based on the overall intentional binding effect to control for non-cardiac factors, and then compared between SZ and HC.ResultsOur study revealed a significant difference between SZ and HC groups, with opposite effects of cardiac systole on SoA. …”
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  5. 745
  6. 746

    Bispecific antibodies: unleashing a new era in oncology treatment by Lin Shui, Dan Wu, Kaixuan Yang, Chuntang Sun, Qingli Li, Rutie Yin

    Published 2025-08-01
    “…Compared with the combination of two monoclonal antibodies, BsAbs represent the physical integration of dual specificities, demonstrating superior binding efficacy, reducing the risk of drug resistance, and enabling unique biological functions such as bridging tumor cells and T cells to achieve precise cytotoxicity. …”
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    Article
  7. 747

    Biomathematical enzyme kinetics model of prebiotic autocatalytic RNA networks: degenerating parasite-specific hyperparasite catalysts confer parasite resistance and herald the birt... by Magnus Pirovino, Christian Iseli, Joseph A Curran, Bernard Conrad

    Published 2025-01-01
    “…While molecular parasites have traditionally been viewed as a nuisance, our model argues for their integration into the host habitat rather than their separation. …”
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    Article
  8. 748

    Structural and functional characterization of the recombinant death domain from death-associated protein kinase. by Evangelos Dioletis, Andrew J Dingley, Paul C Driscoll

    Published 2013-01-01
    “…CD analysis revealed that binding of DAPk-DD to ERK2 is not accompanied by a significant change in secondary structure. …”
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    Article
  9. 749

    StreaMD: the toolkit for high-throughput molecular dynamics simulations by Aleksandra Ivanova, Olena Mokshyna, Pavel Polishchuk

    Published 2024-11-01
    “…Other features of StreaMD are seamless integration with calculation of MM-GBSA/PBSA binding free energies and protein-ligand interaction fingerprints, and running of simulations within distributed environments. …”
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    Article
  10. 750

    The Application of Molecularly Imprinted Polymers in Forensic Toxicology: Issues and Perspectives by Susan Mohamed, Simone Santelli, Arianna Giorgetti, Guido Pelletti, Filippo Pirani, Paolo Fais, Jennifer P. Pascali

    Published 2024-12-01
    “…Molecularly imprinted polymers (MIPs) are synthetic receptors designed to selectively bind specific molecules, mimicking natural antibody–antigen interactions. …”
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    Article
  11. 751

    JUND plays a genome-wide role in the quiescent to contractile switch in the pregnant human myometrium. by Nawrah Khader, Anna Dorogin, Oksana Shynlova, Jennifer A Mitchell

    Published 2025-06-01
    “…Total RNA-sequencing reveals a global increase in primary transcript levels at TL, with AP-1/JUND binding motifs overrepresented in the promoters of upregulated transcripts. …”
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  12. 752

    Androgen receptor profiling predicts prostate cancer outcome by Suzan Stelloo, Ekaterina Nevedomskaya, Henk G van der Poel, Jeroen de Jong, Geert JLH van Leenders, Guido Jenster, Lodewyk FA Wessels, Andries M Bergman, Wilbert Zwart

    Published 2015-09-01
    “…Based on this, we assessed genomewide androgen receptor/chromatin binding and identified a distinct androgen receptor/chromatin binding profile between primary prostate cancers and tumors with an acquired resistance to therapy. …”
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  13. 753

    Characterization of the Antibiotic and Copper Resistance of Emergent Species of Onion-Pathogenic <i>Burkholderia</i> Through Genome Sequence Analysis and High-Throughput Sequencing... by Jonas J. Padilla, Marco A. S. da Gama, Inderjit Barphagha, Jong Hyun Ham

    Published 2025-02-01
    “…In the same analysis, genes related to penicillin binding, the TCA cycle, and FAD binding were found to hinder bacterial adaptation to copper toxicity. …”
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  14. 754

    Structure of associative heterarchical memory by R. V. Dushkin, V. A. Lelekova, V. Y. Stepankov, S. Fadeeva

    Published 2022-10-01
    “…Here, abstract symbol binding was performed using multi-serial integration, eventually converting the primary symbols produced by the program into integrated abstract symbols. …”
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  15. 755

    MODELING AS A METHOD FOR SCIENTIFIC COGNITION OF COMPLEX MEAT SYSTEMS by Marina A. Nikitina, Aleksandr N. Zakharov, Victoria V. Nasonova, Andrey B. Lisitsyn

    Published 2017-10-01
    “…The paper examines the issues associated with the integration of knowledge in meat product technology + computers + mathematical methods. …”
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  16. 756

    In Silico Network Toxicology, Molecular Docking, and Multi‐Level Bioinformatics Reveal Methyl Eugenol‐Induced Hepatocellular Carcinoma Mechanisms in Humans by Fuat Karakuş, Zübeyde Tanrıverdi, Burak Kuzu

    Published 2025-05-01
    “…Molecular docking studies demonstrated weak binding affinities of ME to these targets compared to their specific inhibitors. …”
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  17. 757

    The role of HPV16 regulatory region methylation in viral oncogenes E6 and E7 eхpression in primary cervical cancer lesions by P. M. Abramov, A. N. Katargin, M. D. Fedorova, N. P. Kisseljova, L. S. Pavlova, S. V. Vinokurova

    Published 2019-01-01
    “…These data suggest that methylation of E2 binding sites in HPV16 regulatory region blocking E2 protein binding represents an important mechanism ensuring high level of the viral E6 and E7 oncogenes expression.…”
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  18. 758
  19. 759

    Antioxidant and Anticancer Mechanisms of Unique Polyphenols in <i>Camellia ptilophylla</i>: Focus on Gallocatechin-3,5-di-O-gallate and 1,2,4,6-Tetra-O-galloyl-β-D-glucopyranose by Langhua Zhou, Sen Lu, Xiong Gao, Zhongzheng Chen, Yuanyuan Zhang, Weixia Zhong, Fuming Zhu, Bin Li, Xiaorong Lin

    Published 2025-04-01
    “…This study employs an integrated approach combining chromatographic separation, bioinformatic analysis, and cellular assays to systematically investigate the antioxidant and anticancer properties of <i>C. ptilophylla</i> and elucidate its underlying molecular mechanisms. …”
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  20. 760

    Execution of Judgments and Advisory Opinions of the Court of the Eurasian Economic Union by P. P. Myslivskiy

    Published 2021-10-01
    “…The similarities and differences of judicial acts of the EAEU Court – binding decisions and non-binding advisory opinions – are considered. …”
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    Article