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Showing 41 - 60 results of 2,442 for search 'binding integration', query time: 0.13s Refine Results
  1. 41

    RNA binding proteins (RBPs) on genetic stability and diseases by Abdullahi Tunde Aborode, Ohilebo Abdulateef Abass, Shaibu Nasiru, Mary Ugunnushe Eigbobo, Sumana Nefishatu, Abdullahi Idowu, Zainab Tiamiyu, Aeshah A. Awaji, Nike Idowu, Babawale Roqeeb Busayo, Qasim Mehmood, Isreal Ayobami Onifade, Sodiq Fakorede, Ashraf Akintayo Akintola

    Published 2025-03-01
    “…RNA-binding proteins (RBPs) are integral components of cellular machinery, playing crucial roles in the regulation of gene expression and maintaining genetic stability. …”
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    Article
  2. 42

    Deep Learning for Predicting Biomolecular Binding Sites of Proteins by Minjie Mou, Zhichao Zhang, Ziqi Pan, Feng Zhu

    Published 2025-01-01
    “…The rapid evolution of deep learning has markedly enhanced protein–biomolecule binding site prediction, offering insights essential for drug discovery, mutation analysis, and molecular biology. …”
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    Article
  3. 43

    DNA–Protein Binding is Dominated by Short Anchoring Elements by Hong Chen, Yongping Xu, Hao Ge, Xiao‐Dong Su

    Published 2025-05-01
    “…This method allows for the direct identification of the dominant role of AEs from experimental data. Moreover, when integrated with genomic data, it reveals an energetic funnel around transcription factor binding sites (TFBSs), which is directly correlated with the density of AEs (AED). …”
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    Article
  4. 44

    The next generation of transcription factor binding site prediction. by Anthony Mathelier, Wyeth W Wasserman

    Published 2013-01-01
    “…Moreover, using available TF-DNA affinity measurements for the Max TF, we demonstrate that TFFMs constructed from ChIP-seq data correlate with published experimentally measured DNA-binding affinities. Finally, TFFMs allow for the straightforward computation of an integrated TF occupancy score across a sequence. …”
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    Article
  5. 45
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  7. 47

    Global analysis of small molecule binding to related protein targets. by Felix A Kruger, John P Overington

    Published 2012-01-01
    “…We report on the integration of pharmacological data and homology information for a large scale analysis of small molecule binding to related targets. …”
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    Article
  8. 48

    Selective Enrichment of Hypermethylated DNA by a Multivalent Binding Platform by Ruben W. Kolkman, Loes I. Segerink, Jurriaan Huskens

    Published 2022-12-01
    “…In the here proposed method, a methyl binding domain (MBD) protein immobilized at a surface is used as a receptor for (hyper)methylated DNA. …”
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    Article
  9. 49
  10. 50

    Allosteric binding sites in Rab11 for potential drug candidates. by Ammu Prasanna Kumar, Suryani Lukman

    Published 2018-01-01
    “…Although they are medically important, no previous study has found Rab11 allosteric binding sites where potential drug candidates can bind to. …”
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    Article
  11. 51

    Proteome-wide determinants of co-translational chaperone binding in bacteria by Carla Verónica Galmozzi, Frank Tippmann, Florian Wruck, Josef Johannes Auburger, Ilia Kats, Manuel Guennigmann, Katharina Till, Edward P. O´Brien, Sander J. Tans, Günter Kramer, Bernd Bukau

    Published 2025-05-01
    “…Here, by integrating genome-wide selective ribosome profiling, single-molecule tools, and computational predictions using AlphaFold we show that the binding of the main E. coli chaperones involved in co-translational folding, Trigger Factor (TF) and DnaK correlates with “unsatisfied residues” exposed on nascent partial folds – residues that have begun to form tertiary structure but cannot yet form all native contacts due to ongoing translation. …”
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    Article
  12. 52

    Competitive dCas9 binding as a mechanism for transcriptional control by Daniel A Anderson, Christopher A Voigt

    Published 2021-11-01
    “…Natural promoters use overlapping binding sites as a mechanism for signal integration, where the binding of one can block, displace, or augment the activity of the other. …”
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    Article
  13. 53

    Odors drive feeding through gustatory receptor neurons in Drosophila by Hongping Wei, Thomas Ka Chung Lam, Hokto Kazama

    Published 2025-08-01
    Subjects: “…odor-taste multisensory integration…”
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    Article
  14. 54
  15. 55

    Model of Organizational Structure for University Institutes Binding with the Venezuelan Socioeconomic Reality by Rafael Pertuz Belloso

    Published 2014-01-01
    “…The present study is aimed at proposing a model of organizational structure for university institutes binding with the Venezuelan socioeconomic reality. …”
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    Article
  16. 56

    Intra‐ and inter‐chromosomal interactions correlate with CTCF binding genome wide by Marco Botta, Syed Haider, Ian X Y Leung, Pietro Lio, Julien Mozziconacci

    Published 2010-11-01
    “…In this report, we use chromatin immunoprecipitation (ChIP) data that map protein‐binding sites on the genome, and Hi‐C data that map interactions between DNA fragments in the genome in an integrative approach. …”
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    Article
  17. 57
  18. 58

    Identification of druggable binding sites and small molecules as modulators of TMC1 by Pedro De-la-Torre, Claudia Martínez-García, Paul Gratias, Matthew Mun, Paula Santana, Nurunisa Akyuz, Wendy González, Artur A. Indzhykulian, David Ramírez

    Published 2025-05-01
    “…Our pipeline successfully identified three potential drug-binding sites within the TMC1 pore, phospholipids, and key amino acids involved in the binding of several compounds, as well as FDA-approved drugs that reduced dye uptake in cultured cochlear explants. …”
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    Article
  19. 59

    A Beautiful Bind: Phage Display and the Search for Cell-Selective Peptides by Babak Bakhshinejad, Saeedeh Ghiasvand

    Published 2025-07-01
    “…Phage display has advanced the discovery of peptides that selectively bind to a wide variety of cell surface molecules, offering new modalities to modulate disease-related protein–protein interactions (PPIs). …”
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    Article
  20. 60

    POT1 stability and binding measured by fluorescence thermal shift assays. by Lynn W DeLeeuw, Robert C Monsen, Vytautas Petrauskas, Robert D Gray, Lina Baranauskiene, Daumantas Matulis, John O Trent, Jonathan B Chaires

    Published 2021-01-01
    “…The results from these assays provide thermodynamics details of POT1 folding, the sequence selectivity of its DNA binding and the thermodynamic profile for its binding to its preferred DNA binding sequence. …”
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    Article