RBM14 enhances transcriptional activity of p23 regulating CXCL1 expression to induce lung cancer metastasis by Wen Zhang, Yulin Peng, Meirong Zhou, Lei Qian, Yilin Che, Junlin Chen, Wenhao Zhang, Chengjian He, Minghang Qi, Xiaohong Shu, Manman Tian, Xiangge Tian, Yan Tian, Sa Deng, Yan Wang, Xiaokui Huo, Zhenlong Yu, Xiaochi Ma

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p52-ZER6/DAZAP1 axis promotes ferroptosis resistance and colorectal cancer progression via regulating SLC7A11 mRNA stabilization by Li Qiu, Wenfang Li, Lei Zhang, Xia Zhang, Hezhao Zhao, Makoto Miyagishi, Shourong Wu, Vivi Kasim

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Neon dimers in momentum and configuration spaces by R. Ahnouch, M. R. Hadizadeh

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ARNT-dependent HIF-2α signaling protects cardiac microvascular barrier integrity and heart function post-myocardial infarction by Karim Ullah, Lizhuo Ai, Yan Li, Lifeng Liu, Qin Zhang, Kaichao Pan, Zainab Humayun, Lin Piao, Albert Sitikov, Qiong Zhao, Qiaozhu Su, Willard Sharp, Yun Fang, David Wu, James K. Liao, Rongxue Wu

“…Interestingly, ARNT, but not HIF2α, directly binds the IL-6 promoter to suppress its expression. …”
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Early Detection Tool for Bladder Cancer Based on Quantum Dots Fluorescence Integrated with Fuzzy Logic Classification Application Programming Interface by Krisna Seiya Ekiawan, Evan Manuel Tan, Levina Nasywa Faustin, Verousson Ahmad, Ajeng Lintang Kinasih Suroso, Taufiq Nur Budaya, Nurussa’adah Nurussa’adah

“…This tool is analyzed using fluorescence resonance energy transfer, integrated application programming interface, and fuzzy logic classification, which can work non-invasively.…”
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Isolation of phytochemicals and exploration the mechanism of Dolichandrone spathacea in the treatment of chronic bronchitis by integrating network pharmacology, molecular docking,... by Dang-Khoa Nguyen, Ta-Wei Liu, Man-Hsiu Chu, Quoc-Dung Tran Huynh, Truc-Ly Thi Duong, Thuy-Tien Thi Phan, Duyen Thi My Huynh, Yun-Han Wang, Shu-Mei Wang, Su-Jung Hsu, Ching-Kuo Lee

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Examining Prenylated Xanthones as Potential Inhibitors Against Ketohexokinase C Isoform for the Treatment of Fructose-Driven Metabolic Disorders: An Integrated Computational Approa... by Tilal Elsaman, Magdi Awadalla Mohamed

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Integrative Machine Learning, Virtual Screening, and Molecular Modeling for BacA-Targeted Anti-Biofilm Drug Discovery Against Staphylococcal Infections by Ahmad Almatroudi

“…Active compounds were retrieved from BindingDB while the decoy was generated from DUDE. …”
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Dietary copper improves intestinal structural integrity in juvenile grass carp (Ctenopharyngodon idella) probably related to its increased intestinal antioxidant capacity and apica... by Rui Ma, Lin Feng, Pei Wu, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Shu-Wei Li, Ling Tang, Xiao-Qiu Zhou, Wei-Dan Jiang

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Repurposing antiviral drugs targeting the PARP-1 and HER2 pathways with multifaceted impacts through integrated network analysis and molecular mechanics by Uma Maheshwari Mugundan, Praveen Sekar, Rajanandh Muhasaparur Ganesan

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Understanding mechanisms of Polygonatum sibiricum-derived exosome-like nanoparticles against breast cancer through an integrated metabolomics and network pharmacology analysis by Tingwen Ming, Yang Yang, Bing Shang, Zhihao Li, Fangling Ren, Lun Wu, Shuya Zhang, Jun Zhu, Qinhua Chen, Jingjian Liu

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Mapping the Interactome of KRAS and Its G12C/D/V Mutants by Integrating TurboID Proximity Labeling with Quantitative Proteomics by Jiangwei Song, Busong Wang, Mingjie Zou, Haiyuan Zhou, Yibing Ding, Wei Ren, Lei Fang, Jingzi Zhang

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Multi-omics integration reveals Vha68-3 as a testicular aging-specific factor that coordinates spermatid elongation through mitochondrial metabolic homeostasis by Jun Yu, Qiuru Huang, Yangbo Fu, Lei He, Cong Shen, Xia Chen, Zhiran Li, Jiaxin Li, Chenyu Wang, Xinda Wang, Binbin Yang, Ziwen Lin, Chen Qiao, Xiaofang Tan, Xiaoqing Yang, Hao Chen, Ying Zheng, Bo Zheng, Fei Sun

“…Multi-omics study was mainly conducted through single-cell RNA sequencing and transcriptome–metabolomics association analysis. Vha68-3 binding proteins were identified via liquid chromatography–tandem mass spectrometry. …”
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The engineering toolbox of Parageobacillus thermoglucosidasius by Marie Millgaard, Belinda Escher, Ivan Pogrebnyakov, Alex Toftgaard Nielsen

“…Here, vectors were categorised either as replicative vectors intended for gene expression, or integrative vectors intended for genomic engineering. …”
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Discovery of compound 1105486 as a selective inhibitor of B4GALT1: potential for pancreatic cancer therapy by Xu Yunyun, Mou Yiping

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Integrated lncRNA and mRNA analysis reveals the immune modulatory mechanisms of antimicrobial peptide BSN-37 in mouse peritoneal macrophages by Huihui Zhang, Yanhe Lv, Jingjing Li, Bingze Jiao, Jiahui Fu, Xujie Zhao, Likun Cheng, Yilin Bai, Lei Wang, Yanwei Li, Bolin Hang, Xiaobing Wei, Mingcheng Liu, Zhanwei Teng, Meinan Chang, Chengshui Liao, Yueyu Bai, Xiaojing Xia, Ke Ding, Jianhe Hu

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Proteome-wide identification of druggable targets and inhibitors for multidrug-resistant Pseudomonas aeruginosa using an integrative subtractive proteomics and virtual screening ap... by Divya Vemula, Vasundhra Bhandari

“…Following this, inverse virtual screening of 464,867 compounds from the VITAS-M library, performed using Schrödinger's Glide module, initially pinpointed 15 potent hits with favorable binding affinities and pharmacokinetic profiles as confirmed by QikProp analysis. …”
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Rad3 decorates critical chromosomal domains with gammaH2A to protect genome integrity during S-Phase in fission yeast. by Sophie Rozenzhak, Eva Mejía-Ramírez, Jessica S Williams, Lana Schaffer, Jennifer A Hammond, Steven R Head, Paul Russell

“…Schizosaccharomyces pombe Rad3 checkpoint kinase and its human ortholog ATR are essential for maintaining genome integrity in cells treated with genotoxins that damage DNA or arrest replication forks. …”
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Profiling of Potential Anti-Diabetic Active Compounds in White Tea: An Integrated Study of Polyphenol-Targeted Metabolomics, Network Pharmacology, and Computer Simulation by Weiwei Wu, Zhiqiang Zheng, Zhihui Wang, Chenxi Gao, Yilin Liang, Wen Zeng, Weijiang Sun

“…These compounds were found to exert their effects by interacting with core molecular targets, namely cathepsin V (CTSV) and nucleotide-binding oligomerization domain-containing protein 1 (NOD1), and engaging in pathways related to signal transduction, apoptosis, and immune responses. …”
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Unveiling the impact of bisphenol a exposure on gene expression and immune response in diabetic nephropathy through integrative toxicogenomics and molecular dynamics approaches by Yan Zhang, Shan Lu, Yijun Dong, Jin Shang

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