Integrated assessment and prediction of transcription factor binding. by Andreas Beyer, Christopher Workman, Jens Hollunder, Dörte Radke, Ulrich Möller, Thomas Wilhelm, Trey Ideker

“…However, measurement of chromatin binding does not necessarily imply regulation, and binding may be difficult to detect if it is condition or cofactor dependent. …”
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Integrated analysis of the functions and prognostic values of RNA-binding proteins in neuroblastoma. by Jun Yang, Jiaying Zhou, Cuili Li, Shaohua Wang

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Transcription factor binding sites are genetic determinants of retroviral integration in the human genome. by Barbara Felice, Claudia Cattoglio, Davide Cittaro, Anna Testa, Annarita Miccio, Giuliana Ferrari, Lucilla Luzi, Alessandra Recchia, Fulvio Mavilio

“…We report a bioinformatic analysis of the distribution of transcription factor binding sites (TFBSs) flanking >4,000 integrated proviruses in human hematopoietic and non-hematopoietic cells. …”
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Exploring Visuo-Tactile Temporal Binding Window Plasticity in Obsessive-Compulsive Disorder by Francesca Rastelli, Davide Fausto Borrelli, Francesca Ferroni, Anna Di Donna, Laura Dell’Uva, Maurizio Cavazza, Matteo Tonna, Martina Ardizzi

“…Among these, the temporal binding window (TBW) specifically refers to the temporal range within which stimuli are perceived as simultaneous and integrated. …”
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Controlled Functionalization Strategy of Proteins Preserves their Structural Integrity While Binding to Nanocarriers by Ana Mateos‐Maroto, Meiyu Gai, Maximilian Brückner, Volker Mailänder, Svenja Morsbach, Katharina Landfester

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Gammaretroviruses tether to mitotic chromatin by directly binding nucleosomal histone proteins by Madushi Wanaguru, Kate N. Bishop

“…Alterations to the CTD of MLV p12 prevented the viral pre-integration complex (PIC) tethering to host chromatin in mitosis, and this could be partially rescued by addition of a heterologous chromatin binding motif. …”
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GS-DTA: integrating graph and sequence models for predicting drug-target binding affinity by Junwei Luo, Ziguang Zhu, Zhenhan Xu, Chuanle Xiao, Jingjing Wei, Jiquan Shen

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Integrated Information Theory and the Phenomenal Binding Problem: Challenges and Solutions in a Dynamic Framework by Chris Percy, Andrés Gómez-Emilsson

Subjects: “…integrated information theory…”
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Binding and bonding of commercialization and collaboration by KPIs: An integrated approach for sustainable agriculture research performance management by Prabath Chaminda Abeysiriwardana, Udith Krishantha Jayasinghe-Mudalige

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Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration by Zachary Ingram, Christopher Kline, Alexandra K. Hughson, Parmit K. Singh, Hannah L. Fischer, Rajalingham Radhakrishnan, Gregory A. Sowd, Nayara F. B. Dos Santos, Barbie K. Ganser-Pornillos, Simon C. Watkins, Melissa Kane, Alan N. Engelman, Zandrea Ambrose

“…However, disruption of CypA binding to the mutant capsid restored nuclear entry, integration, and infection in a CPSF6-dependent manner. …”
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An integrated model of multiple-condition ChIP-Seq data reveals predeterminants of Cdx2 binding. by Shaun Mahony, Matthew D Edwards, Esteban O Mazzoni, Richard I Sherwood, Akshay Kakumanu, Carolyn A Morrison, Hynek Wichterle, David K Gifford

“…To reliably characterize such condition-specific regulatory binding we introduce MultiGPS, an integrated machine learning approach for the analysis of multiple related ChIP-seq experiments. …”
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Integrated experimental and computational analysis reveals amoxicillin binding dynamics to PBP1a in Staphylococcus aureus by Seifeldin Elabed, Mariam Ali, Shrouk Hanafy, Sohila Mostafa, Momen Mamdouh, Ayman Meselhi

“…In vitro antibacterial assays against S. aureus ATCC 43,300 (MRSA) revealed that Amox-MNPs exhibited a mean inhibition zone diameter of 26.0 ± 0.82 mm, approximately double that of free amoxicillin (13.5 ± 1.12 mm) at equivalent concentrations (p < 0.05), indicating significantly enhanced antibacterial efficacy. Integrated computational modeling, including molecular docking and dynamics simulations, elucidated the favorable binding (−8.64 kcal/mol docking score;−32.65 kcal/mol MM-PBSA energy) and stable interaction dynamics between amoxicillin and PBP1a, identifying key stabilizing residues. …”
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An integrated pipeline for the genome-wide analysis of transcription factor binding sites from ChIP-Seq. by Eloi Mercier, Arnaud Droit, Leping Li, Gordon Robertson, Xuekui Zhang, Raphael Gottardo

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Beyond awareness: the binding of reflexive mechanisms with the conscious mind: a perspective from default space theory by Ravinder Jerath, Connor Beveridge

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An integrated machine learning approach delineates an entropic expansion mechanism for the binding of a small molecule to α-synuclein by Sneha Menon, Subinoy Adhikari, Jagannath Mondal

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Dual modality feature fused neural network integrating binding site information for drug target affinity prediction by Haohuai He, Guanxing Chen, Zhenchao Tang, Calvin Yu-Chian Chen

“…The model introduces a binding site-focused graph construction approach to extract binding information, enabling more balanced and efficient modeling of drug-target interactions. …”
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Evolutionary origins of synchronization for integrating information in neurons by Takashi Shibata, Takashi Shibata, Noriaki Hattori, Hisao Nishijo, Tsutomu Takahashi, Tsutomu Takahashi, Yuko Higuchi, Yuko Higuchi, Satoshi Kuroda, Kaoru Takakusaki

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Integrated Multi-Omics Profiling Identifies PDZ-Binding Kinase (PBK) as a Novel Prognostic Biomarker in Hepatocellular Carcinoma by Zhang J, Xu Y, Ni X, Mao Z, Xiao H, Chen M, Lin Y, Pan J, Zhang B, Zhang L, Zheng X, Song G, Ge N

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Antioxidant, Protein-Binding, and Copper(II) Ion Sensing Activities of Rhus alata Phytochemicals: An Integrated Experimental and Computational Study by Mehtab Parveen, Uzma, Azmat Ali Khan, Wan Nor Dalila Wan Fauzi, Nurul Huda Abd Kadir, Masooma Siddiqui, Mahboob Alam

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RMDNet: RNA-aware dung beetle optimization-based multi-branch integration network for RNA–protein binding sites prediction by Jiangbo Zhang, Yunhui Peng, Feifei Cui, Zilong Zhang, Shankai Yan, Qingchen Zhang

“…Abstract RNA-binding proteins (RBPs) play crucial roles in gene regulation. …”
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