Prevalence and determinants of incomplete or not at all vaccination among children aged 12–36 months in Dabat and Gondar districts, northwest of Ethiopia: findings from the primary... by Tadesse Awoke Ayele, Kassahun Alemu, Haileab Fekadu Wolde, Destaw Fetene Teshome, Asmamaw Atnafu, Gashaw Andargie, Mezgebu Yitayal, Getu Debalkie Demissie, Endalkachew Dellie, Telake Azale, Bisrat Misganaw Geremew, Adane Kebede, Tsegaye Gebremedhin, Terefe Derso

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Developing an electronic surprise question to predict end-of-life prognosis in a prospective cohort study of acute hospital admissions by Baldev Singh, Nisha Kumari-Dewat, Adam Ryder, Vijay Klaire, Hannah Jennens, Kamran Ahmed, Mona Sidhu, Ananth Viswanath, Emma Parry

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Less than one in five teenage women in Ethiopia know about emergency contraception by Tesfahun Zemene Tafere, Getachew Teshale, Melak Jejaw, Kaleb Assegid Demissie, Lemlem Daniel Baffa, Demiss Mulatu Geberu, Misganaw Guadie Tiruneh, Asebe Hagos

“…A total weighted sample of 3,381 teenage reproductive women were included. …”
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Relationship between peripheral blood miR-146b-5p levels and lymphocyte subsets in patients with sepsis and its predictive value for prognosis: a single-center study by Sha Cheng, Jiaojiao Wang, Pengfei Wang, Xianli Long, Huiling Liu, Xueyin Li, Xiaowei Zhang, Xuemei Zhao, Hang Sun, Chuanxin Wu

“…Survival curves for miR-146b-5p indicated that lower levels of miR-146b-5p (<0.272) were associated with a higher mortality rate (HR 3.063). The absolute counts of lymphocytes (Lym), CD3+ T cells, CD4+ T cells, and CD8+ T cells were significantly lower in the sepsis group compared to the HD group. …”
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Double “acct”: A Distinct Double-peaked Supernova Matching Pulsational Pair Instability Models by C. R. Angus, S. E. Woosley, R. J. Foley, M. Nicholl, V. A. Villar, K. Taggart, M. Pursiainen, P. Ramsden, S. Srivastav, H. F. Stevance, T. Moore, K. Auchettl, W. B. Hoogendam, N. Khetan, S. K. Yadavalli, G. Dimitriadis, A. Gagliano, M. R. Siebert, A. Aamer, T. de Boer, K. C. Chambers, A. Clocchiatti, D. A. Coulter, M. R. Drout, D. Farias, M. D. Fulton, C. Gall, H. Gao, L. Izzo, D. O. Jones, C.-C. Lin, E. A. Magnier, G. Narayan, E. Ramirez-Ruiz, C. L. Ransome, A. Rest, S. J. Smartt, K. W. Smith

“…We measure the rate of SN 2020acct–like events to be <3.3 × 10 ^−8 Mpc ^−3 yr ^−1 at z = 0.07, or <0.1% of the total core-collapse SN rate.…”
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Nonlinear associations of depression and sleep duration with cognitive impairment in older adults with hypertension: findings from a national survey by Hui-Ying Fan, Hui-Ying Fan, Hui-Ying Fan, He-Li Sun, He-Li Sun, Yuan Feng, Qinge Zhang, Hua-Qing Xing, Hua-Qing Xing, Qian-Hua Huang, Qian-Hua Huang, Zhaohui Su, Teris Cheung, Chee H. Ng, Yu-Tao Xiang, Yu-Tao Xiang, Gang Wang

“…Depression and cognitive function were measured using the 10-item Center for Epidemiological Studies Short Depression Scale and Mini Mental State Examination, respectively. Univariate, binary logistic regression, and restricted cubic spline regression analyses were used to examine the associations between depression, sleep duration and cognitive impairment.ResultsA total of 3,989 older adults with hypertension were included. …”
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COVID-19 severity and vaccine effectiveness in Malawi: A test-negative case-control study by Clara Sambani, Victor Chikwapulo, Regina Mankhamba, Tonny Muwonge, Mavuto Thomas, Baxter Salatiel, Edna Mandala, Leah Mbabazi, Suzan Nakasendwa, Rodgers R. Ayebare, Collins Mitambo, Matthew Kagoli, Mabvuto Chiwaula, Dzinkambani Kambalame, Triza Chirwa, Liness Chinyamunyamu, Tamrat Shaweno, Nebiyu Dereje, Tajudeen Raji, Francis Kakooza, Mosoka P. Fallah, Evelyn C. Banda, Abigail Kazembe, Mitch Matoga

“…For vaccine effectiveness (VE), conditional logistic regression modelling was used, while disease severity and management were analysed using binary logistic regression. Results: The unvaccinated were at 53.3%, and 35.8% were fully vaccinated and/or received a booster. …”
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Decreased Insulin Sensitivity and Impaired Fibrinolytic Activity in Type 2 Diabetes Patients and Nondiabetics with Ischemic Stroke by Aleksandra Jotic, Tanja Milicic, Nadezda Covickovic Sternic, Vladimir S. Kostic, Katarina Lalic, Veljko Jeremic, Milija Mijajlovic, Ljiljana Lukic, Natasa Rajkovic, Milorad Civcic, Marija Macesic, Jelena P. Seferovic, Jelena Stanarcic, Sandra Aleksic, Nebojsa M. Lalic

“…Si was lower in A versus B (1.18±0.67 versus 2.82±0.61 min−1/mU/L × 104; P<0.001) and in C versus D (3.18±0.93 versus 6.13±1.69 min−1/mU/L × 104; P<0.001). …”
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Heat shock protein 90α may serve as a biomarker for mild cognitive impairment in type 2 diabetes mellitus patients without diabetic nephropathy by Hui Zhang, Meiyan Chi, Meiyan Chi, Songtao Feng, Wenwen Zhu, Hongxiao Wang, Wan Zhou, Bing Song, Wei Wang, Wei Wang, Haoqiang Zhang

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THE ACHIEVABILITY OF TARGET CONVECTION VOLUMES IN ON-LINE HEMODIAFILTRATION by A. B. Sabodash, G. A. Zemchenkov, N. S. Kazantseva, K. A. Salikhova, O. V. Makarova, Y. Y. Proletov, A. Y. Zemchenkov

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Human-centred design bolsters vaccine confidence in the Philippines: results of a randomised controlled trial by Till Bärnighausen, Rachel P Chase, Mark Donald C Reñosa, Shannon A McMahon, Jonas Wachinger, Kate Bärnighausen, Jhoys Landicho-Guevarra, Vivienne Endoma, Jeniffer Landicho, Thea Andrea Bravo, Maria Paz Demonteverde, Jerric Rhazel Guevarra, Mila F Aligato, Carol Malacad, Catherine Silvestre

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Analysis of risk characteristics related to ICU and death in children with severe HFMD in Guangxi by LAN Qiyuan, JU Yu, PAN Peijiang, ZHENG Zhigang, LU Zhenwei, FENG Juntan, PENG Yuanjun, LIAO Yanyan, WANG Hailong, ZHOU Lijuan, LIANG Hao, CHEN Minmei, YE Li

“…Bloody foaming sputum, shallow shortness of breath, pale complexion, cyanosis of lips and vomiting were the risk symptoms of death (OR=19.045, 5.438, 3.175, 3.031, 2.621, respectively). Conclusion Children with severe HFMD who have symptoms such as ataxia, delirium, and cyanosis of lips have a higher probability of further developing into critical illness and receiving intensive care. …”
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Hypoperfusion Intensity Ratio as an Indirect Imaging Surrogate in Patients With Anterior Circulation Large‐Vessel Occlusion and Association of Baseline Characteristics With Poor Co... by Omar Hamam, Julie Gudenkauf, Rawan Moustafa, Andrew Cho, Daniel Montes, Muhannad Sharara, Abdallah Moustafa, Mahla Radmard, Mehreen Nabi, Kevin Chen, Sadra Sepehri, Christopher Shin, Ishan Mazumdar, Minsoo Kim, Alireza Mohseni, Ajay Malhotra, Javier Romero, Vivek Yedavalli

“…Multivariable logistic regression showed that patients with AIS caused by cardioembolic and cryptogenic causes (adjusted odds ratio [OR], 2.67; 95% CI, 1.20–5.97; P=0.016), those who presented with admission National Institutes of Health Stroke Scale score ≥12 (adjusted OR, 3.12; 95% CI, 1.61–6.04; P=0.001), and male patients (adjusted OR, 2.06; 95% CI, 1.13–3.77; P=0.018) were associated with poor CS. …”
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Knowledge, practice, and factors affecting peripheral intravenous catheters among nurses working in Dessie City public hospitals by Belachew Tegegne, Dawit Checkole, Mekuriaw Wuhib Shumye, Leul Mekonnen Zeru, Zemen Mengesha Yalew, Sewunet Ademe, Metadel Tegegne Shiferaw, Afework Edmealem

“…Age 30–39 years (AOR = 0.23, 95% CI: 0.09, 0.58, P = 0.002), Diploma (AOR = 4.85, 95% CI: 1.96, 11.98, P = 0.01), experience (AOR = 0.48, 95% CI: 0.25–0.9, P = 0.023), pediatric ward (AOR = 2.79, 95% CI: 1.07, 7.27, P = 0.036), workload (AOR = 2.24, 95% CI: 1.17, 4.3, P = 0.016), frequency of handling PIVC (AOR = 3.83, 95% CI: 1.15, 12.68, P = 0.028), and good knowledge (AOR = 4.97, 95% CI: 3.06, 8.06, P = 0.0001) were factors of practice. …”
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Spectral CT imaging for assessment of metastases in melanoma patients: multi-reader evaluation by Christian Nelles, Philip Rauen, Franziska Meyer, Anja Dobrostal, Pia Lena Niederau, Hasan Zaytoun, Mathilda Weisthoff, Pascale Bernard, Carola Heneweer, Thomas Dratsch, David Maintz, Jonathan Kottlors, Nicole Kreuzberg, Nils Große Hokamp, David Zopfs, Thorsten Persigehl, Simon Lennartz

“…Conventional images (CI), color-coded iodine overlays (IO) and virtual monoenergetic images at 40 keV (VMI40keV) were reconstructed. 6 radiologists (3 experienced with 6 to 9 years and 3 less experienced with 2 to 4 years of experience) read all cases in a CI-based session, and a session based on a combination of CI, IO and VMI40keV. …”
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Nurses’ nutritional care practice and associated factors for hospitalized surgical patients; the case of referral hospitals in Bahir Dar City, Ethiopia by Alamirew Enyew Belay, Mulusew Andualem Asemahagn, Kibret Enyew Belay, Aynamaw Embiale Tesega, Gebrehiwot Berie Mekonnen, Yeshimebet Tamir Tsehay, Sosina Tamre Mamo, Mengistu Abebe Messelu, Tiruye Azene Demile, Henok Biresaw Netsere, Wubet Tazeb Wondie, Gebremeskel Kibret Abebe, Ousman Adal, Sileshi Mulatu, Asnake Gashaw Belayneh

“…Female nurses (AOR = 2.69, 95% CI, 1.62, 4.44), nutrition guidelines (AOR = 2.59, 95% CI, 1.52, 4.39), physician order (AOR = 1.82 95% CI, 1.11, 3.00), experience sharing with peers (AOR = 1.74, 95%CI 1.05, 2.87) nurse to patient ratio < 1:5 (AOR = 1.75, 95%CI, 1.01, 3.02), were positively associated with their practice. …”
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Spatial distribution and factors associated with HIV testing among adolescent girls and young women in Sierra Leone by Augustus Osborne, Camilla Bangura, Samuel Maxwell Tom Williams, Alusine H. Koroma, Lovel Fornah, Regina M. Yillah, Bright Opoku Ahinkorah

“…The likelihood of HIV testing was higher among adolescent girls and young women who had sex below 18 [aOR = 4.54, 95% CI = 3.25, 6.34] and those who had sex at 18+ [aOR = 5.70, 95% CI = 3.84, 8.45] compared to those who had never had sex. …”
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Comparing cervical cerclage, pessary and vaginal progesterone for prevention of preterm birth in women with a short cervix (SuPPoRT): A multicentre randomised controlled trial. by Natasha L Hezelgrave, Natalie Suff, Paul Seed, Vicky Robinson, Jenny Carter, Helena Watson, Alexandra Ridout, Anna L David, Susana Pereira, Fatemeh Hoveyda, Joanna Girling, Latha Vinayakarao, Rachel M Tribe, Andrew H Shennan, SuPPoRT Collaborating Team

“…<h4>Methods and findings</h4>SuPPoRT was a multicentre, open label 3-arm randomised controlled trial designed to demonstrate equivalence (equivalence margin 20%) conducted from 1 July 2015 to 1 July 2021 in 19 obstetric units in the United Kingdom. …”
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Influencing factors of intraoperative blood transfusion and prognosis in lung transplant patients by YANG Huaying, QIANG Xinchen, SUN Lingling, SHAO Junliang

“…The non-transfusion group had lower levels of preoperative pCO2(mmHg)[41.4(37.4, 45.8)vs 45.3(40, 52.48)], postoperative TBIL (μmol/L)[25.45(17.68, 33.95)vs 30.8(21.55, 43.05)], postoperative pH (7.41±0.09 vs 7.45±0.10), bilateral lung transplantation [27(38.6%) vs 157(63.1%)], surgical duration (h) [5(4, 7)vs 6.5(5, 8)], use of ECMO [52(74.3%) vs 232(93.2%)], and intraoperative blood loss (mL)[600(500, 800)vs 1 000(800, 1 500)] compared to the transfusion group (all P<0.05). …”
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Endo-Periodontal Lesions in Endodontically Treated Teeth with Periapical Pathology by Mihaela Sălceanu, Anca Melian, Cristina Dascălu, Cristian Giuroiu, Corina Concita, Claudiu Topoliceanu, Diana Melian, Andreea Frumuzache, Sorina Mihaela Solomon, Maria-Alexandra Mârţu

“…To evaluate the combined effect of the identified risk factors, a binary logistic regression model was constructed using the Enter method. …”
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