Fecal carriage of multidrug-resistant organisms increases the risk of hepatic encephalopathy in patients with cirrhosis: insights from gut microbiota and metabolite features by Pei-Shan Wu, Pei-Chang Lee, Tien-En Chang, Yun-Cheng Hsieh, Chi-Wei Huang, Chao-Hsiung Lin, Yi-Long Huang, Yi-Tsung Lin, Teh-Ia Huo, Bernd Schnabl, Kuei-Chuan Lee, Ming-Chih Hou

“…Methods Eighty-eight patients with cirrhosis and 22 healthy volunteers were analyzed for plasma metabolites, fecal MDROs, and microbiota composition. …”
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HDL proteome and apolipoproteins concentrations in severe ICU COVID-19 patients by Floran Begue, Bryan Veeren, Philippe Rondeau, Aline-Marie Florence, Simon Jamard, Philippe Montravers, Sébastien Tanaka, Olivier Meilhac, on behalf of French COVID Study Group

“…Abstract Background SARS-CoV-2 infection affects both lipid metabolism and lung function. …”
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Chemical, optical, and morphological properties of TPU and PET-G samples after aging in artificial saliva: an in vitro study by Edoardo Staderini, Giuseppe Chiusolo, Massimiliano Papi, Mario Palone, Luca Lombardo, Massimo Cordaro

“…Abstract Background Thermoplastic materials, such as glycol-modified polyethylene terephthalate (PET-G) and thermoplastic polyurethane (TPU), undergo alterations due to environmental factors in the oral cavity, which can affect their composition and surface properties over time. …”
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The Single Nucleotide Polymorphism PPARG2 Pro12Ala Affects Body Mass Index, Fat Mass, and Blood Pressure in Severely Obese Patients by Ana Paula dos Santos Rodrigues, Lorena Pereira Souza Rosa, Hugo Delleon da Silva, Elisângela de Paula Silveira-Lacerda, Erika Aparecida Silveira

“…Background. The PPARG2 Pro12Ala (rs1801282) and IL6 -174G >C (rs1800795) have important function in body weight regulation and a potential role in obesity risk. …”
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Delites™ supplementation prevents metabolic syndrome onset and modulates gut microbiome in male Sprague Dawley rats fed on cholesterol- and fat-enriched diet: a randomized preclini... by Juan Leonardo, Robby Hertanto, Reggie Surya, Rony Abdi Syahputra, Wardina Humayrah, Nindy Sabrina, Nurpudji Astuti Taslim, Trina Ekawati Tallei, Raymond Rubianto Tjandrawinata, Fahrul Nurkolis, Fahrul Nurkolis, Fahrul Nurkolis

“…Delites™, a supplement inspired by Traditional Chinese Medicine, has shown potential in modulating gut microbiota and mitigating MetS.ObjectivesThis study aimed to evaluate the effects of Delites™ supplementation on metabolic health and gut microbiota composition in male Sprague Dawley rats fed a cholesterol- and fat-enriched diet (CFED).MethodsA randomized preclinical trial was conducted on 32 rats divided into four groups: control-normal, CFED, CFED+low-dose Delites™ (54 mg/kg), and CFED+high-dose Delites™ (108 mg/kg). …”
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Molecular endotypes in sepsis: integration of multicohort transcriptomics based on RNA sequencing by Kengo Mekata, Michihito Kyo, Modong Tan, Nobuaki Shime, Nobuyuki Hirohashi

“…Abstract Background The heterogeneity of host responses in sepsis has hindered efforts to develop targeted therapies for this large patient population. …”
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Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice by Shiyue Sun, Tongtong Yu, Joo Young Huh, Yujie Cai, Somy Yoon, Hafiz Muhammad Ahmad Javaid

“…Abstract Background Duchenne muscular dystrophy (DMD) is a prevalent, fatal degenerative muscle disease with no effective treatments. …”
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Lipophilic Extracts of <i>Portulaca oleracea</i> L.: Analysis of Bioactive Fatty Acids Targeting Microbial and Cancer Pathways by Dejan Stojković, Jelena Živković, Stefani Bolevich, Gokhan Zengin, Mehmet Veysi Cetiz, Sergey Bolevich, Marina Soković

“…<b>Methods:</b> Chemical analysis was conducted to determine the fatty acid composition of the extracts. …”
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Cytotoxic effect of different Uncaria tomentosa (cat’s claw) extracts, fractions on normal and cancer cells: a systematic review by Adriana A. Lopes, Juliana da Silva Coppede, Pedro de Pádua G. Amatto, Davi Casale Aragon, Suzelei de Castro França, Fabio Carmona, Ana Maria S. Pereira, Ana Maria S. Pereira

“…The observed cytotoxic effects vary considerably depending on the extraction method and chemical composition, underscoring the need for standardization in future studies. …”
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Antibacterial effect of femtosecond laser against Enterococcus faecalis and Fusobacterium nucleatum biofilms on dentin: an in vitro study by Pei Liu, Runze Liu, Yi Luo, Wei Fan, Bing Fan

“…This study investigated the antibacterial effect of femtosecond laser (fs-laser) against Enterococcus faecalis (E. faecalis) and Fusobacterium nucleatum (F. nucleatum) biofilms on dentin. Methods The chemical composition of dentin slices from extracted human teeth was analyzed using FTIR and Raman probes. …”
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Side-by-Side Comparison of Culture Media Uncovers Phenotypic and Functional Differences in Primary Mouse Aortic Mural Cells by Iman Ghasemi, Rajinikanth Gogiraju, Sana’a Khraisat, Sven Pagel, Claudine Graf, Moritz Brandt, Thati Madhusudhan, Philip Wenzel, Guillermo Luxán, Philipp Lurz, Magdalena L. Bochenek, Katrin Schäfer

“…Whether and how cultivation conditions affect their phenotype and function is often overlooked. (2) Methods: Here, we systematically studied how the cultivation of primary mural cells isolated from the aorta of adult wild-type mice in either basal medium (DMEM) or special media formulated for the cultivation of fibroblasts or pericytes affects their phenotype and function. (3) Results: Medium composition did not alter cell viability, but the mRNA levels of differentiated smooth muscle cell markers were highest in vascular mural cells expanded in DMEM. …”
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In vitro and in vivo investigations of selected varieties of Areca catechu L - Phytochemical analysis, antiulcer, and wound healing activity by R. Deveswaran, D.J. Madhu Kumar, V. Madhavan, Soma Chaki, Misbah Khan, Govind R. Kadambi, B.V. Basavaraj, J. Anbu

“…Background: This study investigated the phytochemical composition and potential medicinal properties of arecanut grown in various regions of Karnataka. …”
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Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial by Sunan Gao, Hongyu Dai, Qian Hao, Jiale Song, Kang Ji, Hongwei Xu, Gang Chen, Jian Lu

“…Abstract Background Postoperative cognitive dysfunction (POCD) may last for days, months or even years, leading to prolonged hospitalization and increased costs, increased mortality, and poor quality of life. …”
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Effects of maternal Echinococcus multilocularis infection on colitis susceptibility and gut microbiota of offspring by Yihui Liu, Yang Xu, Yang Zou, Yingying Ding, Jiayun Zhang, Ying Zhang, Quanhai Pang, Shuai Wang

“…However, it remains unclear whether these effects can be transferred between maternal mice and their offspring during tissue-dwelling helminth infections. Methods In this study, we investigated the effect of maternal infection with Echinococcus multilocularis (Emu) on offspring susceptibility to colitis and gut microbiota composition using a dextran sulfate sodium (DSS)-induced colitis model. …”
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Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study. by H Raza Ali, Leon Chlon, Paul D P Pharoah, Florian Markowetz, Carlos Caldas

“…<h4>Background</h4>Immune infiltration of breast tumours is associated with clinical outcome. …”
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Associations of MIND and DI-GM dietary scores with depression, anxiety, and gut microbiota in patients with colon cancer: a cross-sectional study by Yaqin Meng, Jing Tian, Xiu Xiu Li, Zhou Xu

“…BackgroundDietary patterns influence psychological health, systemic inflammation, and gut microbiota composition in colon cancer patients. …”
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Effects of a 6-Week Concurrent Training Program Combining Resistance and Various Modalities of Aerobic Exercise in Obese Women with Prehypertension: A Randomized Controlled Trial by Jinhyuk Yu, Eunjoo Lee, Jae-Ho Choi, Yerin Sun, Seungyeon Woo, Sohyang Cho, Deunsol Hwang, Sung-Woo Kim, Jisu Kim, Kiwon Lim, Hun-Young Park

“…<b>Background/Objectives</b>: Our study aimed to verify the effects of 6 weeks of concurrent training composed of resistance training (RT) and different modalities of aerobic exercise (moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT)) on body composition, blood pressure, vascular function, autonomic nervous system (ANS) function, blood lipid levels, cardiometabolic index (CMI), and health-related fitness in obese middle-aged women with prehypertension. …”
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Tongue-coating microbiota as a predictive biomarker of washed microbiota transplantation efficacy in pediatric autism: integration with clinical features by Hao-Jie Zhong, Zhao-Yu Pan, Yao-Fei Wei, Qian Yu, Lei Wu, Hong Wei, Xing-Xiang He

“…Abstract Background Alterations in both oral and gut microbiota have been identified in children with autism spectrum disorder (ASD), but the interaction between these microbiota and their potential to predict outcomes of fecal microbiota transplantation (FMT) remain poorly understood. …”
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NT2-derived astrocyte–neuron co-culture reflects physiological relevance and offers research validity by Sylwia Kedracka-Krok, Ewelina Fic, Zuzanna Cepil, Piotr Rybczyński, Agata Szlaga, Radosław Cacała, Sławomir Lasota, Anna Blasiak, Marta Dziedzicka-Wasylewska

“…Ntera-2 cells and NT2 cells are used interchangeably in this publication. Methods Using an advanced proteomic approach, we assessed the protein composition and abundance of neuron and astrocyte co-cultures and discovered that the astrocytic protein profile in co-culture with neurons was more representative compared with that in pure astrocyte cultures. …”
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Integrating gut microbiome and neuroplasticity genomics in alcohol use disorder therapy by Ilias Koutromanos, Evangelia Legaki, Nikolas Dovrolis, Efthimios Vassilopoulos, Arthur Stem, Vasilis Vasiliou, Elias Tzavellas, Maria Gazouli

“…Abstract Background Alcohol Use Disorder (AUD) is a chronic neuropsychiatric condition with substantial public health impact. …”
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