Ultra-Performance Liquid Chromatography-Quadrupole-Time-of-Flight-Mass Spectrometry-Based Analysis of Facial Physiological Parameters and Lipid Composition of Between Sensitive Ski... by Yu Li, Rong Tang, Lizhi Yue, Congfen He

“…Methods: We used UPLC-Q-TOF-MS technology to study the changes in lipid composition in the sensitive skin of woman aged 36–42 and 43–49 years, using a multi-probe adapter system with different types of skin-testing probes to test physiological parameters. …”
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A composite 18F-FDG PET/CT and HER2 tissue-based biomarker to predict response to neoadjuvant pertuzumab and trastuzumab in HER2-positive breast cancer (TBCRC026)Key Points: by Maeve A. Hennessy, Ashley Cimino-Mathews, Jodi M. Carter, Jennifer M. Kachergus, Yaohua Ma, Jeffrey P. Leal, Lilja B. Solnes, Vandana G. Abramson, Lisa A. Carey, Mothaffar Rimawi, Jennifer Specht, Anna Maria Storniolo, Christos Vaklavas, Ian Krop, Eric Winer, Rita Denbow, Vincente Valero, Antonio C. Wolff, Richard L. Wahl, Chiung-Yu Huang, Vered Stearns, E. Aubrey Thompson, Roisin M. Connolly

“…Background: Early metabolic change on PET/CT was predictive of response to neoadjuvant trastuzumab/pertuzumab (HP) in TBCRC026. …”
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Association between the nutritional inflammation index and mortality among patients with sepsis: insights from traditional methods and machine learning-based mortality prediction by Yuanshuo Ge, Ding Hu, Zhe Wang, Cheng Zhang

“…Abstract Background Sepsis is a life-threatening condition characterized by dysregulated immune responses and metabolic disturbances. …”
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Better Assessment of Progress of SDG 8 by Satyendra Chakrabartty

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Management of large tympanic membrane perforations – A comparative study by Saaketh Boddupalli, Sreenivas Gouripeddi

“…Background: This study aimed to compare the results of tympanoplasty with temporalis fascia graft alone and with composite graft in cases of inactive mucosal-type chronic suppurative otitis media with subtotal and total perforations in graft uptake and hearing improvement. …”
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Regularized win ratio regression for variable selection and risk prediction, with an application to a cardiovascular trial by Lu Mao

“…Abstract Background The win ratio has been widely used in the analysis of hierarchical composite endpoints, which prioritize critical outcomes such as mortality over nonfatal, secondary events. …”
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Effect of thermomechanical aging on marginal fit of three CAD-CAM restorative materials: An in vitro study by Reda Eid Attia, Hussein Ramadan Mohammed, Khaled Mohamed Haggag

“…Background. The present study assessed the impact of thermomechanical aging on the marginal fit of hybrid ceramic, reinforced composite resin, and lithium disilicate ceramic. …”
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Characteristics and Pattern of Calcified Nodule and/or Nodular Calcification Detected by Intravascular Ultrasound on the Device-Oriented Composite Endpoint (DoCE) in Patients with... by Ploy Pengchata, Rungtiwa Pongakasira, Namthip Wongsawangkit, Asa Phichaphop, Nattawut Wongpraparut

“…Background. The characteristics and pattern of a CN and/or NC on clinical outcome remain unknown. …”
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New Composite Indexes through Factor Analysis Simplifying the Interpretation of Health-Related Quality of Life Outcomes of Surgical Adolescent Idiopathic Scoliosis Patients Complet... by Wai-Wang Chau, Bobby Kin-Wah Ng

“…In view of a total of 14 (9 + 5) major domain scores from both questionnaires, this study attempted to develop new composite indexes using factor analysis. Materials and Methods: All operated AIS patients within the years 2014 and 2016 were recruited. …”
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mPEG-PCL Nanoparticles to Improve Oral Bioavailability of Acalabrutinib: Effect of Polymer Lipophilicity and Hydrophilicity on Physicochemical Properties and In Vivo Performance in... by Swagata Sinha, Punna Rao Ravi, Sahadevan Rajesh Rashmi, Łukasz Szeleszczuk

“…The ACP-loaded PLHNs (ACP-PLHNs) were optimized using a circumscribed central composite design. The in vivo studies were performed in Wistar rats. …”
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Clinical evaluation of SonicFill bulk resin technique in the restoration of proximal deep caries of primary molars: a two-year randomized controlled trial by Yingting Yang, Haihua Lei, Yang Liu, Bin Xia

“…Abstract Background/purpose Traditional restorative composites require time-consuming incremental layering techniques which poses challenges in pediatric dentistry. …”
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Chronic non-bacterial osteomyelitis in children- five-year standardized follow-up of a prospective observational cohort in the pre-biological era by Christine Hofmann, Annette Holl-Wieden, Christiane Reiser, Meinrad Beer, Peter Raab, Henner Morbach, Hermann J. Girschick

“…Methods Patients were assessed at baseline and at 1 (without MRI), 3, 6, 12, 18, 24, 36, 48, 60 months. …”
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Are ethnic and gender specific equations needed to derive fat free mass from bioelectrical impedance in children of South asian, black african-Caribbean and white European origin?... by Claire M Nightingale, Claire M Nightingale, Alicja R Rudnicka, Christopher G Owen, Angela S Donin, Sian L Newton, Cheryl A Furness, Emma L Howard, Rachel D Gillings, Jonathan C K Wells, Derek G Cook, Peter H Whincup

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A protocol for estimating health burden posed by early life exposure to ambient fine particulate matter and its heavy metal composition: a mother–child birth (ELitE) cohort from Ce... by Tanwi Trushna, Vikas Yadav, Vikas Yadav, Uday Kumar Mandal, Vishal Diwan, Vishal Diwan, Rajnarayan R. Tiwari, Rajnarayan R. Tiwari, Rajesh Ahirwar, Rajesh Ahirwar, Dharma Raj, Sindhuprava Rana, Sindhuprava Rana, Suchitra Vishwambhar Surve, Sagnik Dey, Sagnik Dey, Yogesh Damodar Sabde, Yogesh Damodar Sabde

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Correlations between serum BDNF levels and neurodevelopmental outcomes in infants of mothers with gestational diabetes by Chung-Hao Su, Ta-Yu Liu, I.-Ting Chen, Mei-Chen Ou-Yang, Li-Tong Huang, Ching-Chang Tsai, Chih-Cheng Chen

“…Background: Diabetes during pregnancy is associated with an increased risk of foetal and neonatal complications and long-term complications in the offspring. …”
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Physical activity and factors associated with the costs of low back pain among adults after 18 months of follow-up: a cohort study by Everton Alex Carvalho Zanuto, Valter Penna, Cristiano Rocha da Silva, Enio Ricardo Vaz Ronque, Ruben de Faria Negrão Filho, Robson Chacon Castoldi, Jamile Sanches Codogno, Rômulo Araújo Fernandes

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Evaluating and enhancing the service capacity of secondary public hospitals in urban China: a multi-method empirical analysis based on Guangzhou (2019–2023) by Baoling Wu, Baoling Wu, Wenbo Wu, Xi Wang, Weizhang Huang, Zhenni Luo, Jifeng Li

“…This study aims to systematically evaluate the evolution and spatial dynamics of service capacity among secondary general public hospitals in Guangzhou, offering empirical evidence to support capacity improvement and policy optimization.MethodsA composite evaluation framework was constructed across three dimensions: medical quality, operational efficiency, and sustainability. …”
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Assessing healthcare status and challenges in border regions: insights from Tak and Mae Hong Son provinces, Thailand – a mixed-method approach by Seo Ah Hong, Mathuros Tipayamongkholgul, Chit Su Tinn, Bang-on Thepthien

“…Abstract Background Thailand’s Tak and Mae Hong Son (MHS) provinces, bordering Myanmar, are critical entry points for individuals seeking employment or healthcare. …”
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Reduction of Salt and Sugar Contents in Canteen Foods and Intakes By Students and Staff at a Malaysian Higher Education Institution: Protocol for a Mixed Methods Study by Yook Chin Chia, Yee-How Say, Maong Hui Cheng, Felicia Fei Lei Chung, Tze Pheng Lau, Pei Boon Ooi

“… BackgroundUniversity students and staff members, especially those who frequently eat out and spend considerable time on campus, form a crucial demographic facing challenges related to high salt and sugar intake in out-of-home food. …”
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Efficiency evaluation of phospholipid fatty acid method based on lipid standards: methanol failed to recover a majority of phospholipids yet eluted unexpected glycolipid by Shanshan Zhang, Shanshan Zhang, Xinyu Jiao, Hongzhang Kang, Wenjuan Yu, Wenjuan Yu

“…Overall, incomplete separation among lipid types caused loss of phospholipids and introduction of glycolipid interferences in the methanol fraction, leading to biased estimation of soil microbial biomass and composition. Chloroform elution of phospholipids challenges the principle of “like dissolves like” in solid-phase chromatography, although we cannot rule out the uncertainty caused by background PLFAs and future experiments are needed to provide more evidence. …”
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