Investigation of the pharmacological activity of the tetrapeptide HAEЕ, zinc, and human serum albumin in a transgenic mouse model with tau protein overexpression (P301S) by Veronika S. Shmigerova, Yulia V. Stepenko, Alexandra A. Kurbatova, Nikita S. Zhunusov, Nikita S. Lyapkalov, Maria S. Sviridova, Tatyana V. Avtina, Arkadiy V. Nesterov, Alexander A. Popov, Natalia I. Nesterova, Mariia Iu. Goltsova, Tatiana G. Pokrovskaya

“…Materials and Methods: The experiment was performed on 60 homozygous mice of both sexes from a transgenic line with the overexpression of human mutant tau protein (P301S) and on 20 mice from a wild-type C57Bl/6J background line. …”
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Is lean mass quantity or quality the determinant of maximal fat oxidation capacity? The potential mediating role of cardiorespiratory fitness by Edgardo Opazo-Díaz, Juan Corral-Pérez, Alejandro Pérez-Bey, Alberto Marín-Galindo, Adrián Montes-de-Oca-García, María Rebollo-Ramos, Daniel Velázquez-Díaz, Cristina Casals, Jesús-Gustavo Ponce-González

“…The aim is to analyze the associations of lean-mass, muscle strength and quality with fat oxidation parameters in young adults, considering the mediating role of VO2max.Methods A cross-sectional observational study. Eighty-one adults (50 males, 31 females; age 22.8 ± 4.4, BMI 25.70 ± 5.75, lean-mass 54.19 ± 8.78, fat-mass 18.66 ± 11.32) Body composition assessment by bioimpedance determine fat and lean-mass. …”
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Development of a quality by design based eco-friendly RP-HPLC method for Ticagrelor and Aspirin by Shivani Jani, Ujashkumar Shah, Jayvadan Patel, Monika Dua

“…Objective: To design and validate a green, QbD-based RP-HPLC technique for simultaneous estimation of TICA and ASP in drug products. Methods: A 3-factor factorial design based on Response Surface Methodology (RSM) optimized important parameters: organic solvent composition, flow rate, and column temperature. …”
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Development and validation of a stability-indicating RP-HPLC method for tizanidine hydrochloride using DOE by Prasad Gunjal, Janki Patel

“…A full factorial design was implemented, optimizing mobile phase composition and flow rate as key method variables. Chromatographic separation was achieved using an Agilent Zorbax Bonus RP column (250 × 4.6 mm, 5 µm) with a mobile phase of 0.1% trifluoroacetic acid (TFA) and acetonitrile (65:35 v/v) at a 0.5 mL/min flow rate. …”
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Beyond BMI: a comprehensive approach to pediatric obesity assessment by Norma Cipatli Ayuzo Del Valle, Norma Cipatli Ayuzo Del Valle, Perla Pérez-Treviño, Ana Carla Cepeda Lopez, Ana Carla Cepeda Lopez, Regina M. Murillo-Torres, Elena Cristina Castillo, Diego Gutierrez-Cantu, Oscar Tamez-Rivera, Oscar Tamez-Rivera, Mayela Paez Flores, Isabella Flores-Ayuzo, Luis Alberto Luévano-Martinez, Sergio Javier Fernandez Ortiz, Sergio Javier Fernandez Ortiz, Noemí García, Leonardo Mancillas-Adame

“…The 2025 Obesity Classification Framework proposed by The Lancet Diabetes & Endocrinology Commission integrates body fat distribution and metabolic biomarkers, aiming to enhance diagnostic accuracy in pediatric obesity.MethodsWe evaluated 111 physically active children (aged 5–11 years) from the Monterrey Football League in Mexico using both the traditional BMI-based classification and the new 2025 Obesity Classification Framework, which incorporates body composition (measured by bioelectrical impedance analysis), waist-to-height ratio, and metabolic biomarkers. …”
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Hypercaloric 16:8 time-restricted eating during 8 weeks of resistance exercise in well-trained men and women by Daniel T. Blake, Cody Hamane, Chelscie Pacheco, Menno Henselmans, Grant M. Tinsley, Pablo Costa, Jared W. Coburn, Thomas Campidell, Andrew J. Galpin

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Survey on the current practice of research ethics committees in the Czech academic environment: a mixed-methods study by Renata Veselska, Jan Sirucek, Josef Kure

“…Abstract Background The primary objective of this study was to conduct a comprehensive questionnaire survey on the practices of research ethics committees reviewing academic research projects in Czechia. …”
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Research and Development in the Field of Creating Materials, Technologies and Safety Equipment by V. A. Bogush, L. V. Lynkou, N. V. Nasonova, S. L. Prischepa, E. S. Belousova, O. V. Boiprav, H. V. Davydau, V. A. Papou, A. V. Patapovich, H. A. Pukhir

“…Technologies for the manufacture of microwave electromagnetic shields based on powdered carbon, foil and composite multilayer materials are presented. Technological methods for their manufacture and shielding properties are described, and the main mechanisms leading to increased shielding properties are considered depending on the manufacturing technology, composition and alternation of composite layers. …”
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Microbiome matters: how transplantation methods and donor origins shape the successful restoration of the seagrass Posidonia oceanica by Arnaud Boulenger, Tânia Aires, Aschwin H. Engelen, Gerard Muyzer, Michel Marengo, Sylvie Gobert

“…Abstract Background Posidonia oceanica forms extensive seagrass meadows in the Mediterranean Sea, providing key ecosystem services. …”
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The unresolved struggle of 16S rRNA amplicon sequencing: a benchmarking analysis of clustering and denoising methods by Mohamed Fares, Engy K. Tharwat, Ilse Cleenwerck, Pieter Monsieurs, Rob Van Houdt, Peter Vandamme, Mohamed El-Hadidi, Mohamed Mysara

“…Abstract Background Although 16S rRNA gene amplicon sequencing has become an indispensable method for microbiome studies, this analysis is not error-free, and remains prone to several biases and errors. …”
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Group-wise normalization in differential abundance analysis of microbiome samples by Dylan Clark-Boucher, Brent A. Coull, Harrison T. Reeder, Fenglei Wang, Qi Sun, Jacqueline R. Starr, Kyu Ha Lee

“…Abstract Background A key challenge in differential abundance analysis (DAA) of microbial sequencing data is that the counts for each sample are compositional, resulting in potentially biased comparisons of the absolute abundance across study groups. …”
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Comparative Evaluation of Surface Roughness of Different Composite Restorative Materials after Thermocycling and Prolonged Immersion in Common Beverages Using Atomic Force Microsco... by Akanksha Malik, Anjali K. Kothari, Riya Dave, Vinay V. Rao, Kaushal Vyas, Deep P. Agrawal, Kishan Patel

“…Background: Direct composite restorations face abrupt temperature changes, varying pH, and surface deterioration in the oral environment. …”
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Effect of vitamin D supplementation on body composition, lipid profile, and glycemic indices in patients with obesity-associated metabolic syndrome: a systematic review and meta-an... by Lili Ge, Shi Gao, Najaf Kia, Yanzhong Wang, Liqun Hua

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The influence of thermal tempering on the fracture resistance, surface microstructure, elemental surface composition, and phase analysis of four heat-pressed lithia-based glass cer... by Khaled Nasser, Amr EL-Etreby, Soha Osama Nabih

“…Abstract Background This in-vitro study aimed to evaluate the impact of thermal tempering and ceramic type on the fracture resistance, surface microstructure, elemental surface composition and phase analysis of four heat-pressed glass ceramics. …”
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Neutrophil-to-lymphocyte ratio as a novel predictor of sarcopenia in maintenance hemodialysis patients: a cross-sectional study exploring associations across body composition categ... by Yogesh M., Parth Anilbhai Parmar, Soumya Sharma, Jay Pareshbhai Kakadiya, Dhruv Lakkad

“…Abstract Background Sarcopenia is prevalent among hemodialysis patients and is associated with poor outcomes. …”
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Association of lipid composition with diabetic foot ulcer size and depth: a cross-sectional study on plant versus animal oils, cholesterol, and omega fatty acids by Faezeh Geravand, Ensieh Nasli-Esfahani, Mohsen Montazer, Moharam Jalalzadeh, Leila Azadbakht

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Validity and reliability of anthropometric equations versus Dual X-ray Absorptiometry to estimate body composition in athletes with unilateral lower-limb amputation: A pilot study. by Laura Victoria Rivera-Amézquita, Ximena Saavedra-Bernal, Sofia Diaz-Moreno, Alejandra Tordecilla-Sanders, Diana Carolina Escorcia-Gomez, Diana Marcela Ramos-Caballero, Zdenek Svoboda

“…<h4>Background</h4>Accurate assessment of body composition is essential for monitoring health and performance in high-performance athletes. …”
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Effects of Liupao Tea with Different Years of Aging on Glycolipid Metabolism, Body Composition, and Gut Microbiota in Adults with Obesity or Overweight: A Randomized, Double-Blind... by Yuyang Wang, Qiang Hu, Botian Chen, Defu Ma

“…Background: Liupao tea (LPT) is a traditionally fermented dark tea from Guangxi, China and the effects of different aging periods of LPT on metabolic health remain inadequately explored. …”
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Efficacy and safety of moderate-intensity rosuvastatin plus ezetimibe versus high-intensity rosuvastatin monotherapy in the treatment of composite cardiovascular events with hyperc... by Lingyan Liu, Yongkun Deng, Lei Li, Xingbiao Yang, Zhaoheng Yin, Yong Lai

“…<h4>Objective</h4>To systematically review the efficacy and safety of Moderate-intensity Rosuvastatin Plus Ezetimibe compared with High-intensity Rosuvastatin in treating Composite Cardiovascular Events.<h4>Methods</h4>PubMed, Embase, Cochrane Library, CINAHL, Web of Science, China Knowledge Network, China Biological Literature Database, Wan Fang Database, and Weipu Database were searched to retrieve randomized controlled trials assessing the safety and efficacy of the two therapies from the time of construction to December 2023. …”
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Effect of physical activity and multi-micronutrient supplementation on body composition among Tanzanian schoolchildren: secondary outcomes from the KaziAfya cluster-randomized cont... by Elihaika G. Minja, Emmanuel C. Mrimi, Winfrida P. Mponzi, Johanna Beckmann, Marceline F. Finda, Fredros O. Okumu, Christin Lang, Markus Gerber, Jürg Utzinger, Kurt Z. Long

“…Abstract Background Childhood overweight and obesity are increasing in low- and middle-income countries, including Tanzania, due to changing lifestyles and diets. …”
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