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Facilitation of Tumor Stroma-Targeted Therapy: Model Difficulty and Co-Culture Organoid Method
Published 2025-01-01“…This review aims to analyze the challenges of stroma mimicry models, and highlight advanced personalized co-culture approaches for recapitulating tumor stroma using patient-derived tumor organoids (PDTOs). <b>Methods:</b> This review synthesizes findings from recent studies on tumor stroma composition, stromal remodeling, and the spatiotemporal heterogeneities of the TME. …”
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Relationship between composite dietary antioxidants index and growth indicators in children aged 3–12 years: results from two observational studies
Published 2025-03-01“…This study aimed to investigate the relationship between the Composite Dietary Antioxidant Index (CDAI) and child growth indicators in two cohorts.MethodsThis study utilized data from 1,064 participants in the Children's Cohort Study on Micronutrient Deficits and Malnutrition (CCSMDM) 2023 database and 2,404 participants from the National Health and Nutrition Examination Survey (NHANES) 2003–2020 database for cross-sectional analyses, with participants aged 3–12 years. …”
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826
IL-17A-producing γδ T cells and classical monocytes are associated with a rapid alloimmune response following vascularized composite allotransplantation in mice
Published 2025-06-01“…BackgroundVascularized Composite Allotransplantation (VCA) is an important therapeutic option for patients that incur debilitating injuries to the face or limbs. …”
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827
Investigating the Effect of Staining Beverages on the Structural and Mechanical Integrity of Dental Composites Using Raman, Fourier Transform Infrared (FTIR) Spectroscopy, and Micr...
Published 2025-03-01“…<i>Background and Objectives</i>: Resin composites are widely used in restorative dentistry due to their favorable mechanical properties and aesthetics. …”
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Changes in microbiome composition after fecal microbiota transplantation via oral gavage and magnetic navigation technology-assisted proximal colon/cecum enema in antibiotic knock-...
Published 2025-05-01“…Abstract Background Fecal microbiota transplantation (FMT) transfers fecal matter from a donor into the gastrointestinal tract of a recipient to induce changes to the gut microbiota for therapeutic benefit; however, differences in the composition of gut microbiota after FMT via different donor material delivery routes are poorly understood. …”
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Antioxidant Activity of Culinary-Processed Food
Published 2024-02-01“…Background: Exogenous compounds with antioxidant activity mainly include plant compounds such as polyphenols, β-carotene, lycopene, vitamin C and vitamin E. …”
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830
Dietary supplementation with citrus peel extract in transition period improves rumen microbial composition and ameliorates energy metabolism and lactation performance of dairy cows
Published 2024-11-01“…Abstract Background During the transition period, excessive negative energy balance (NEB) lead to metabolic disorders and reduced milk yield. …”
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Therapeutic effects of composite probiotics derived from fermented camel milk on metabolic dysregulation and intestinal barrier integrity in type 2 diabetes rats
Published 2025-01-01“…This study evaluates the effects of composite probiotics derived from fermented camel milk (CPCM) on metabolic disturbances in a rat model of Type 2 diabetes (T2DM).MethodsT2DM was induced in Wistar rats using streptozotocin. …”
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832
The influence of a vegan diet on body composition, performance and the menstrual cycle in young, recreationally trained women– a 12-week controlled trial
Published 2024-12-01“…Therefore, this study aimed to investigate the influence of a vegan dietary transition and its effects on body composition, physical performance, and menstrual cycle in young, recreationally trained women.Methods Ten young healthy women (23.8 ± 2.0 years, 173.0 ± 5.8 cm) were recruited to participate in this 12-week controlled study (4-week omnivorous phase, 8-week vegan intervention). …”
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QbD enabled optimization study of the variable concentration of phospholipid and stabilizer in the development of liposomal pastilles of solid dispersion polymeric composite of ant...
Published 2025-06-01“…Background: The study aimed to develop and optimize liposomes of the antihypertensive drug Felodipine (FH) using the Quality by Design (QbD) approach with a 3² Central Composite Design (CCD) in Design Expert software, followed by the development of pastilles. …”
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Deep learning-based body composition analysis from whole-body magnetic resonance imaging to predict all-cause mortality in a large western populationResearch in context
Published 2024-12-01“…Summary: Background: Manually extracted imaging-based body composition measures from a single-slice area (A) have shown associations with clinical outcomes in patients with cardiometabolic disease and cancer. …”
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Game method to increase students' motivation to engage in elective disciplines in physical culture and sports
Published 2021-06-01“…Background and Study Aim. A serious problem when using the play method in training sessions is the regulation of physical activity. …”
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AI-based volumetric six-tissue body composition quantification from CT cardiac attenuation scans for mortality prediction: a multicentre study
Published 2025-05-01“…Summary: Background: CT attenuation correction (CTAC) scans are routinely obtained during cardiac perfusion imaging, but currently only used for attenuation correction and visual calcium estimation. …”
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A generalized equation for predicting peak oxygen consumption during treadmill exercise testing: mitigating the bias from total body mass scaling
Published 2024-12-01“…BackgroundIndexing peak oxygen uptake (VO2peak) to total body mass can underestimate cardiorespiratory fitness (CRF) in women, older adults, and individuals with obesity. …”
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COPING MANUFACTURED TECHNIQUE OF SPINELL SLIP CAST ALL CERAMIC BY CONVENTIONAL METHODS AND CAD/CAM
Published 2019-07-01“…Those steps all can be performed only by scanning, design, and milling by CAD/CAM methods. Besides that, coping result produced by CAD/ CAM methods has good accuracy due to spinell block utilization which has better homogenous composition.…”
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Deep Reinforcement Learning-Based Distribution Network Planning Method Considering Renewable Energy
Published 2025-03-01“…Distribution networks are an indispensable component of modern economic societies. Against the background of building new power systems, the rapid growth of distributed renewable energy sources, such as photovoltaic and wind power, has introduced many challenges for distribution network planning (DNP), including different source-load compositions, complex network topologies, and varied application scenarios. …”
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