Role and prognostic value of growth differentiation factor 15 in patient of heart failure with preserved ejection fraction: insights from the PURSUIT-HFpEF registry by Tetsuhisa Kitamura, Shungo Hikoso, Takahisa Yamada, Yoshio Yasumura, Akito Nakagawa, Toshihiro Takeda, Hirota Kida, Akihiro Sunaga, Tomoharu Dohi, Katsuki Okada, Daisaku Nakatani, Yasushi Matsumura, Yasushi Sakata, Shunsuke Tamaki, Takaharu Hayashi, Yoshiharu Higuchi, Masaharu Masuda, Mitsutoshi Asai, Toshiaki Mano, Hisakazu Fuji, Daisaku Masuda, Shizuya Yamashita, Masami Sairyo, Yusuke Nakagawa, Haruhiko Abe, Yasunori Ueda, Kunihiko Nagai, Masamichi Yano, Masami Nishino, Jun Tanouchi, Yoh Arita, Shinji Hasegawa, Takamaru Ishizu, Minoru Ichikawa, Yuzuru Takano, Eisai Rin, Tetsuya Watanabe, Shiro Hoshida, Masahiro Izumi, Hiroyoshi Yamamoto, Hiroyasu Kato, Kazuhiro Nakatani, Mayu Nishio, Keiji Hirooka, Takahiro Yoshimura, Akihiro Tani, Yasushi Okumoto, Yasunaka Makino, Katsuomi Iwakura, Yoshiyuki Kijima, Takashi Kitao, Masashi Fujita, Koichiro Harada, Masahiro Kumada, Osamu Nakagawa, Ryo Araki, Takayuki Yamada, Fusako Sera, Kei Nakamoto, Hidetaka Kioka, Tomohito Ohtani, Nobuyuki Ogasawara, Yukinori Shinoda, Koichi Tachibana, Yohei Sotomi, Taiki Sato, Yuji Yasuga, Toshinari Onishi, Kazunori Kashiwase, Ryu Shutta, Masahiro Seo, Yuki Matsuoka, Yasuhiro Akazawa, Daisuke Sakamoto

“…Background Growth differentiation factor 15 (GDF15) is a cytokine responding to oxidative stress and inflammation, and it regulates appetite and energy balance. …”
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Patient-reported Outcome Measures and Decision Regret After Prostate-specific Membrane Antigen–targeted Radioguided Surgery for Oligorecurrent Prostate Cancer by Fabian Falkenbach, Giovanni Mazzucato, Zhe Tian, Pierre I. Karakiewicz, Markus Graefen, Thomas Steuber, Derya Tilki, Daniel Koehler, Burkhard Beyer, Pierre Tennstedt, Sophie Knipper, Lars Budäus, Tobias Maurer

“…Data on patient-reported outcome measures (PROMs) are lacking. Methods: A retrospective assessment of validated PROMs (12-item Short Form Health Survey [SF-12], 26-item Expanded Prostate Index Composite, and Decision Regret Scale [DRS]) was performed before and after PSMA-RGS for oligorecurrent PCa. …”
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Antibodies against integrin αvβ6 have high diagnostic accuracy for ulcerative colitis by Patrick Bez, Martina Scapolan, Davide Giuseppe Ribaldone, Gian Paolo Caviglia, Silvia Zago, Cristina Trucco, Simone Frara, Antonino Caruso, Marta Ascolani, Michele Campigotto, Stefano Benvenuti, Stefano Martelossi, Lara De Lucchi, Marta Favero, Francesco Cinetto, Francesco Cinetto, Elisabetta Faggin, Laura Ventura, Marcello Rattazzi, Marcello Rattazzi, Tilde Manetta, Giulio Mengozzi, Antonio Antico, Carla Felice, Carla Felice

“…BackgroundAnti-integrin αvβ6 IgG autoantibodies showed good sensitivity and optimal specificity in ulcerative colitis (UC) compared to controls. …”
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Clinical Features and Outcomes of Pediatric MYH7‐Related Dilated Cardiomyopathy by Fernando de Frutos, Juan Pablo Ochoa, Gregory Webster, Mark Jansen, Paloma Remior, Torsten B. Rasmussen, Maria Sabater‐Molina, Roberto Barriales‐Villa, Francesca Girolami, Sergi Cesar, M. Eugenia Fuentes‐Cañamero, Reyes Alvarez García‐Rovés, Karim Wahbi, Javier Limeres, Milos Kubanek, Martijn G. Slieker, Georgia Sarquella‐Brugada, Dominic J. Abrams, Dennis Dooijes, Fernando Domínguez, Pablo Garcia‐Pavia

“…Background Although genetic variants in MYH7 are the most frequent cause of pediatric genetic dilated cardiomyopathy (DCM), there are no studies available describing this entity. …”
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The SmartNTx-study: a prospective, randomized controlled trial to investigate additional interventional telemedical management versus standard aftercare in kidney transplant recipi... by Mario Schiffer, Lars Pape, Julia K. Wolff, Julia K. Wolff, Raoul Gertges, Vanessa Visconti, Karen Reichert, Anja Pfau, Anne Dieterle, Katja Sauerstein, Andreas Kribben, Kristina Boss, Sinem Karaterzi, Felix Nensa, Philipp Winneckens, Mario Cypko, Mario Cypko, Wiebke Duettmann, Bianca Zukunft, Eva Schrezenmeier, Marcel G. Naik, Fabian Halleck, Roland Roller, Sebastian Möller, Sebastian Möller, Oliver Amft, Oliver Amft, Klemens Budde

“…BackgroundRegular follow-up care after kidney transplantation is performed in transplant centers together with local nephrologist practices in Germany. …”
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Indobufen versus aspirin after percutaneous coronary intervention in elderly patients with acute coronary syndrome by Wenbo Dai, Guanyu Mu, Jiayi Ren, Sutao Hu, Rongxin Guo, Tian-shu Gu, Jingjin Che, Xianghong Ma, Tong Liu, Xue Wu, Jing-Kun Zhang, Gary Tse, Yajie Wang, Jian-Mei Zhou, Seung-Woon Rha, Kangyin Chen

“…Abstract Background Antiplatelet therapy is pivotal in managing elderly patients with Acute Coronary Syndrome (ACS) following Percutaneous Coronary Intervention (PCI). …”
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Perceived technology usefulness for caregiving among unpaid caregivers: a National Cross-Sectional Study by Matthew Lee Smith, Matthew Lee Smith, Shinduk Lee, Malinee Neelamegam, Deborah Vollmer Dahlke, Deborah Vollmer Dahlke, Deborah Vollmer Dahlke, Jodi L. Southerland, Zachary G. Baker, Kris Pui Kwan Ma, Darina V. Petrovsky, Zahra Rahemi, Justine S. Sefcik, Juanita-Dawne R. Bacsu, Chung Lin Kew, Chung Lin Kew, Marcia G. Ory, Marcia G. Ory

“…BackgroundTechnological advancements have the potential to improve caregiving quality and alleviate caregiver burden by providing tools for real-time communication, monitoring, and care coordination. …”
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Unraveling the Oncogenic Characteristics of the Cytolinker, Plectin, in Esophageal Squamous Cell CarcinomaSummary by Lili Qiao, Yuanyuan Hu, Lei Xu, Guodong Deng, Xiaohong Yu, Wei Zheng, Yanan Yang, Hui Yuan, Wei Jiang, Xiying Yu

“…Background & Aims: Tissue mechanics involved in carcinogenesis by regulating cell morphology and structure, cell-cell, and cell-extracellular matrix (ECM) interactions are not fully understood. …”
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Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung ade... by Yi-Feng Ren, Qiong Ma, Xiao Zeng, Chun-Xia Huang, Jia-Li Ren, Fang Li, Jia-Jing Tong, Jia-Wei He, Yang Zhong, Shi-Yan Tan, Hua Jiang, Long-Fei Zhang, Heng-Zhou Lai, Ping Xiao, Xiang Zhuang, Peng Wu, Li-Ting You, Wei Shi, Xi Fu, Chuan Zheng, Feng-Ming You

“…Abstract Background Radiographically, ground-glass nodules (GGN) and part-solid nodules (PSN) in lung adenocarcinoma (LUAD) have significant heterogeneity in their clinical manifestations, biological characteristics, and prognosis. …”
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Efficacy and safety of venetoclax and azacitidine for acute myeloid leukemia in China: a real-world single-center study by Jie-Fei Bai, Ting Wang, Jiang-Tao Li, Chun-Li Zhang, Long Qian, Ya-Zi Yang, Xiao-Ya Yun, Jing-Jing Yin, Fei Zhao, Wei-Dong Ding, Bao-Li Xing, Shang-Yong Ning, Lei Pei, Xiao-Dong Xu, Hui Liu, Ru Feng

“…Abstract Background Venetoclax (VEN) and azacitidine (AZA) are used to treat patients with newly diagnosed acute myeloid leukaemia (AML) who are unfit for intensive chemotherapy and those with relapsed or refractory AML. …”
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Metabolic Status and Atrioventricular Block Risk: The Role of Physical Activity by Ho-Gi Chung, Pil-Sung Yang, Eunsun Jang, Daeun Joung, Daehoon Kim, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung

“…Background: The relationship between metabolic status as a possible risk factor and predictor of response to moderate-to-vigorous physical activity (MVPA) in atrioventricular block (AVB) remains unclear. …”
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Effect of obesity on myocardial tissue characteristics in patients with hypertrophic cardiomyopathy: a cardiovascular magnetic resonance-based study by Jie Wang, Lutong Pu, Jinquan Zhang, Ruihao Xu, Yang Li, Mengdi Yu, Yangjie Li, Jiajun Guo, Yuanwei Xu, Yu Kang, Yuchi Han, Yucheng Chen

“…Background: Obesity is associated with cardiac steatosis in healthy adults and is independently associated with increased left ventricular (LV) mass and could contribute to the progression of heart failure-related composite events in patients with hypertrophic cardiomyopathy (HCM). …”
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Efficacy and safety of dapagliflozin in patients hospitalized with COVID-19 with and without type 2 diabetes: a prespecified analysis of the DARE-19 randomized trial by Mohammad Abdel Jawad, Remo H. M. Furtado, Russell Esterline, Jan Oscarsson, Samvel B. Gasparyan, Gary G. Koch, Felipe Martinez, Omar Mukhtar, Subodh Verma, Anna Maria Langkilde, Philip Ambery, Shachi Patel, Kensey Gosch, Sheryl L. Windsor, Ronaldo V. P. Soares, Diogo D. F. Moia, Matthew Aboudara, Ali Javaheri, J. F. Kerr Saraiva, Lilia Nigro Maia, Otavio Berwanger, Andrew J. Sauer, Mikhail N. Kosiborod

“…Abstract Background Although several previous studies tested SGLT2 inhibitors in the setting of an acute, non-cardiovascular illness, detailed information on their efficacy and safety among participants with and without type 2 diabetes (T2D) from double-blind randomized trials is lacking. …”
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Numerical Simulation Study on Stability Control Technology of Large-Area Wall Caving Area (LAWCA) in Large-Inclined Face by Xun Liu, Shihao Tu, Hongsheng Tu, Long Tang, Jieyang Ma, Yan Li, Wenlong Li, Kaijun Miao, Hao Tian

“…After mining, the caving rock mass rolls to the lower part of the working face due to gravity, and the caving compaction characteristics of the working face are different from those of the flat and gently inclined working face, taking Huainan Xinji No. 2 Mine 211112 high-angle composite roof working face large-area gang roof fall area as the engineering background. …”
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A feasibility study on beef tallow conversion to some esters for biodiesel production by Mohamad Ali Ghazavi, Majid Fallahipanah, Hamed Shahmirzae Jeshvaghani

“…The quality of the produced biodiesel is evaluated using Fourier transform infrared spectroscopy (FTIR) method. Results: FTIR analysis showed that the final product contains ester compositions which can be used as biodiesel fuel in diesel engines. …”
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Developing the IDCaRe team: an integrated and culturally-affirming approach to improving health engagement for HIV-positive veterans by James Michael Brennan, Madison B. Bailey, William Hua

“…Background Veterans Health Administration (VHA) has been at the forefront of offering integrated and patient-centered care to address the complex needs of more than 30,000 Veterans with HIV in the United States of America. …”
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Chimeric Free Fibula Osteocutaneus Flap and Massive Allograft for Refractory Post-traumatic Osteomyelitis Femur Defect: A Case Report by Lam HY, Halim AS, Wan-Sulaiman WA

“…The burden of this chronic disease invariably results in composite bony and soft tissue defects that can interfere with bony stability. …”
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A retrospective assessment of COVID-19 vulnerability index indicators and mortality rates pre-COVID-19 (2018–2020) and during COVID-19 (2020–2022) in a health and demographic surve... by Takwanisa Machemedze, Chodziwadziwa Whiteson Kabudula, Jean Juste Harrisson Bashingwa, Beth A. Tippett Barr, Nellie Myburgh, Sana Mahtab, Cleopas Hwinya, Stephen Tollman, Ziyaad Dangor, Shabir A. Madhi

“…Abstract Background Before COVID-19, knowledge on pandemic vulnerability and mortality in South Africa was largely limited to the context of HIV/AIDS. …”
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Cardiac arrest while using the toilet: not uncommon and associated with adverse resuscitation profile by Elizabeth D. Paratz, Carl Johann Hansen, Andre La Gerche, Dion Stub, Ziad Nehme, Ashanti Dantanarayana, Kelila Freedman, Andreas Pflaumer, Jodie Ingles, Bo Gregers Winkel, Jacob Tfelt-Hansen

“…Background: Out-of-hospital cardiac arrest (OHCA) on the toilet has been reported to be common and possibly driven by straining or vagal stimulus. …”
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Artificial intelligence-enhanced comprehensive assessment of the aortic valve stenosis continuum in echocardiographyResearch in context by Jiesuck Park, Jiyeon Kim, Jaeik Jeon, Yeonyee E. Yoon, Yeonggul Jang, Hyunseok Jeong, Youngtaek Hong, Seung-Ah Lee, Hong-Mi Choi, In-Chang Hwang, Goo-Yeong Cho, Hyuk-Jae Chang

“…Summary: Background: Transthoracic echocardiography (TTE) is the primary modality for diagnosing aortic stenosis (AS), yet it requires skilled operators and can be resource-intensive. …”
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