HE4 as a Prognostic Biomarker of Major Adverse Cardiovascular Events in Patients with Abdominal Aortic Aneurysm: A Canadian Prospective Observational Study by Hamzah Khan, Abdelrahman Zamzam, Farah Shaikh, Muhammad Mamdani, Gustavo Saposnik, Mohammad Qadura

“…<b>Background:</b> Abdominal aortic aneurysm (AAA) is a chronic inflammatory disease characterized by the proteolytic breakdown of the extracellular matrix. …”
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Behavioral determinants of dental and facial esthetic self-perception among an academic population: a cross-sectional study by Ana Cristina Mafla, Mauricio Herrera-López, Juliana Estefanía Salas-Burbano, Camilo Andrés Guerrero-Dávila, Diana Paola Insuasty-Fuertes, Juan Sebastián Bustos-López, Falk Schwendicke

“…Abstract Background Facial attractiveness is a relevant feature in many societies, and self-perceived attraction has been shown to affect a wide range of aspects in human lives, including quality of life. …”
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Low Maternal Iodine Status in Early Pregnancy Is Associated with Cognitive and Language Delays at 24 Months in Non-Users of Nutritional Supplements by Áine Hennessy, Lisa Kelliher, Yvonne O’Callaghan, Jillian Brown, Deirdre Murray, Mairead Kiely

“…Background: Severe maternal iodine deficiency has profound consequences for the developing brain; however, the impact of mild to moderate deficiency is less clear, and findings from observational studies have been mixed. …”
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The predictive value of the serum creatinine-to-albumin ratio (sCAR) and lactate dehydrogenase-to-albumin ratio (LAR) in sepsis-related persistent severe acute kidney injury by Xiaoxiao Luo, Dongyang Liu, Cuicui Li, Jia Liao, Wuyang Lv, Yuchen Wang, Ruxue Diao, Yingyu Jin

“…Abstract Background/objectives Sepsis-related acute kidney injury (SA-AKI) is a severe condition characterized by high mortality rates. …”
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Remnant cholesterol inflammatory index, calculated from residual cholesterol to C-reactive protein ratio, and stroke outcomes: a retrospective study using the National institutes o... by Yanmei Yu, Yiming Zhang, Chunyan Zhu, Tingting Duan, Zichen Rao

“…Abstract Background Globally, acute ischemic stroke (AIS) persists as a significant driver of both mortality and prolonged disability. …”
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Infections and antibiotic resistance in Malawian children 6-59 months old hospitalized with severe acute malnutrition by Dr Bryan Vonasek, Ms. Mwawi Nyirongo, Mr. Alexander Kondwani, Dr. Anthony Garcia-Prats, Ms. Tiwonge Kamvaunamwali, Ms. Doris Ng'oma, Mr. James Kaphatika, Mr. Amazing-Grace Tepeka, Dr. Mercy Kumwenda, Dr. Emily Ciccone, Dr. Tisungane Mvalo

“…Background: Severe acute malnutrition (SAM) is strongly associated with mortality in young children, and infections are thought to be a major driver of that mortality. …”
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Profiling of gastric cancer cell-surface markers to achieve tumour–normal discrimination by Henry Yang, Khek Yu Ho, Judith Toh, Michal Marek Hoppe, Teena Thakur, Kar Tong Tan, Brendan Pang, Sharmaine Ho, Rony Roy, Khay Guan Yeoh, Raghav Sundar, Anand Jeyasekharan

“…However, a systematic analysis of cell-surface markers and development of a composite panel involving multiple candidates to differentiate tumour from normal has not been previously reported.Methods Whole transcriptome sequencing (WTS) of GC and matched normal samples from the Singapore Gastric Cancer Consortium (SGCC) was used as a discovery cohort to identify upregulated putative cell-surface proteins. …”
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Treatment responses to Azithromycin and Ciprofloxacin in uncomplicated Salmonella Typhi infection: A comparison of Clinical and Microbiological Data from a Controlled Human Infecti... by Celina Jin, Malick M Gibani, Shaun H Pennington, Xinxue Liu, Alison Ardrey, Ghaith Aljayyoussi, Maria Moore, Brian Angus, Christopher M Parry, Giancarlo A Biagini, Nicholas A Feasey, Andrew J Pollard

“…<h4>Background</h4>The treatment of enteric fever is complicated by the emergence of antimicrobial resistant Salmonella Typhi. …”
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Ultrasound Evaluation of Therapeutic Response to Tofacitinib and Upadacitinib in Patients with Rheumatoid Arthritis—Real-Life Clinical Data by Vladimira Boyadzhieva, Konstantin Tachkov, Soner Emin, Zhaklin Apostolova, Rumen Stoilov, Guenka Petrova, Nikolay Stoilov

“…<b>Background</b>: In recent years, musculoskeletal ultrasonography (MSUS) has established itself as a reliable method for evaluating disease activity in combination with clinical examination and laboratory tests. …”
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Potential Harms of Feedback After Web-Based Depression Screening: Secondary Analysis of Negative Effects in the Randomized Controlled DISCOVER Trial by Franziska Sikorski, Bernd Löwe, Anne Daubmann, Sebastian Kohlmann

“… BackgroundWeb-based depression screening followed by automated feedback of results is frequently used and promoted by mental health care providers. …”
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Translation, Cross-Cultural Adaptation, and Psychometric Validation of the Health Information Technology Usability Evaluation Scale in China: Instrument Validation Study by Rongrong Guo, Ziling Zheng, Fangyu Yang, Ying Wu

“… BackgroundThe dramatic growth of digital health apps highlights an urgent need for rigorous usability evaluation tools. …”
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A short-term predictive model for disease progression in acute-on-chronic liver failure: integrating spectral CT extracellular liver volume and clinical characteristics by Yuan Xu, Fukai Li, Bo Liu, Tiezhu Ren, Jiachen Sun, Yufeng Li, Hong Liu, Jianli Liu, Junlin Zhou

“…Abstract Background Acute-on-chronic liver failure (ACLF) is a life-threatening hepatic syndrome. …”
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Compliance with smoke-free laws in hospitality venues in Ethiopia: A cross-sectional observational study in 10 cities. by Wakgari Deressa, Selamawit Hirpa, Terefe Gelibo Argefa, Yifokire Tefera, Selam Abraham Kassa, Rachel Kitonyo-Devotsu, Winnie Awuor, Baharu Zewdie, Noreen Dadirai Mdege

“…<h4>Background</h4>The 2019 Ethiopia's comprehensive tobacco control proclamation mandates 100% smoke-free public places and workplaces. …”
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Modulation of Gut Microbiota through Nutritional Interventions in Behçet’s Syndrome Patients: Preliminary Results from the MAMBA Study by Giuditta Pagliai, Silvia Turroni, Federica D’Amico, Irene Mattioli, Marta Tristan Asensi, Giacomo Emmi, Francesco Sofi

“…Background. Recent evidence suggests that the gut microbiota (GM) in Behçet’s syndrome patients (BS) has low diversity and a peculiar layout. …”
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Comparative effectiveness of lactulose and sennosides for the prevention of peritoneal dialysis-related peritonitis: an open-label, randomized, active-controlled trial by Kajohnsak Noppakun, Tichanun Narongchai, Romanee Chaiwarith, Uraiwan Wongsawad, Surachet Vongsanim, Chidchanok Ruengorn, Surapon Nochaiwong

“…Background To the best of our knowledge, the effectiveness and safety of lactulose in comparison to sennosides, for the prevention of peritoneal dialysis (PD)-related peritonitis, has never been tested in a randomized study.Methods We conducted an open-label, randomized, active-controlled trial in a PD-center in Northern Thailand. …”
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Increasing risk of postlung transplant hospitalizations for infection: An analysis of recent trends by Shi Nan Feng, BSPH, Armaan F. Akbar, BS, Alice L. Zhou, MS, Andrew Kalra, BS, Sean Agbor-Enoh, MD, PhD, Christian A. Merlo, MD, MPH, Errol L. Bush, MD

“…Background: Despite advancements in lung transplantation (LT), infection remains a major cause of morbidity and mortality following LT. …”
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Efficacy of tenofovir on clinical outcomes of COVID-19 patients: a systematic review by Thaís Lorenna Souza Sales, Daniella Nunes Pereira, Virginia Mara Reis Gomes, Gabriel Gouveia de Aguiar, Milena Soriano Marcolino

“…Abstract Background Pharmacological treatments for COVID-19 remain limited, particularly for severe outcomes. …”
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Risk factors, management, and outcomes of amniotic fluid embolism: A multicountry, population-based cohort and nested case-control study. by Kathryn E Fitzpatrick, Thomas van den Akker, Kitty W M Bloemenkamp, Catherine Deneux-Tharaux, Alexandra Kristufkova, Zhuoyang Li, Timme P Schaap, Elizabeth A Sullivan, Derek Tuffnell, Marian Knight

“…<h4>Background</h4>Amniotic fluid embolism (AFE) remains one of the principal reported causes of direct maternal mortality in high-income countries. …”
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Thin Strut CoCr Biodegradable Polymer Biolimus A9-Eluting Stents versus Thicker Strut Stainless Steel Biodegradable Polymer Biolimus A9-Eluting Stents: Two-Year Clinical Outcomes by Ian B. A. Menown, Mamas A. Mamas, James M. Cotton, David Hildick-Smith, Franz R. Eberli, Gregor Leibundgut, Damras Tresukosol, Carlos Macaya, Samuel Copt, Sara Sadozai Slama, Keith G. Oldroyd

“…Background. While thinner struts are associated with improved clinical outcomes in bare-metal stents (BMS), reducing strut thickness may affect drug delivery from drug-eluting stents (DES) and there are limited data comparing otherwise similar thin and thick strut DES. …”
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Variation in Venous Thromboembolism Outcomes Based on Primary Cancer Site by Javier Trujillo-Santos, MD, PhD, Cihan Ay, MD, PhD, Behnood Bikdeli, MD, MS, David Jiménez, MD, PhD, Aurora Villalobos, MD, PhD, Luciano López-Jiménez, MD, Montserrat Pérez-Pinar, MD, Javier Pagán-Escribano, MD, PhD, Maurizio Ciammaichella, MD, Manuel Monreal, MD, PhD

“…Background: Patients with cancer-associated venous thromboembolism (VTE) are at increased risk of both recurrent VTE and bleeding. …”
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